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Brandon Leonard, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentOtolaryngology
Address1450 Third St
San Francisco CA 94158
Phone415-514-8084
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    Collapse Biography 
    Collapse Education and Training
    University of Minnesota - Twin CitiesPh.D. 2015Microbology, Immunology and Cancer Biology
    University of California - San DiegoB.S.2008Molecular Biology
    Collapse Awards and Honors
    University of Minnesota - Twin Cities2013  - 2015T32 - Cancer Biology Training Grant

    Collapse Research 
    Collapse Research Activities and Funding
    Exploiting procaspase-8 mutations for therapeutic benefit in HNSCC
    NIH/NIDCR F32DE026949Jul 1, 2017 - Jun 30, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Leonard B, McCann JL, Starrett GJ, Kosyakovsky L, Luengas E, Molan AM, Burns MB, McDougle RM, Parker PJ, Brown WL, Harris RS. The PKC/NF-?B signaling pathway induces APOBEC3B expression in multiple human cancers. Cancer Res. 2015 Nov 01; 75(21):4538-47. PMID: 26420215; PMCID: PMC4631676.
    2. Burns MB, Leonard B, Harris RS. APOBEC3B: pathological consequences of an innate immune DNA mutator. Biomed J. 2015 Mar-Apr; 38(2):102-10. PMID: 25566802.
      View in: PubMed
    3. Vieira VC, Leonard B, White EA, Starrett GJ, Temiz NA, Lorenz LD, Lee D, Soares MA, Lambert PF, Howley PM, Harris RS. Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B. MBio. 2014 Dec 23; 5(6). PMID: 25538195; PMCID: PMC4278539.
    4. Leonard B, Hart SN, Burns MB, Carpenter MA, Temiz NA, Rathore A, Vogel RI, Nikas JB, Law EK, Brown WL, Li Y, Zhang Y, Maurer MJ, Oberg AL, Cunningham JM, Shridhar V, Bell DA, April C, Bentley D, Bibikova M, Cheetham RK, Fan JB, Grocock R, Humphray S, Kingsbury Z, Peden J, Chien J, Swisher EM, Hartmann LC, Kalli KR, Goode EL, Sicotte H, Kaufmann SH, Harris RS. APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. Cancer Res. 2013 Dec 15; 73(24):7222-31. PMID: 24154874; PMCID: PMC3867573.
    5. Burns MB, Lackey L, Carpenter MA, Rathore A, Land AM, Leonard B, Refsland EW, Kotandeniya D, Tretyakova N, Nikas JB, Yee D, Temiz NA, Donohue DE, McDougle RM, Brown WL, Law EK, Harris RS. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature. 2013 Feb 21; 494(7437):366-70. PMID: 23389445; PMCID: PMC3907282.
    6. Carpenter MA, Li M, Rathore A, Lackey L, Law EK, Land AM, Leonard B, Shandilya SM, Bohn MF, Schiffer CA, Brown WL, Harris RS. Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A. J Biol Chem. 2012 Oct 05; 287(41):34801-8. PMID: 22896697; PMCID: PMC3464582.
    7. Leonard B, Sharma V, Smider V. Co-expression of antibody fab heavy and light chain genes from separate evolved compatible replicons in E. coli. J Immunol Methods. 2006 Dec 20; 317(1-2):56-63. PMID: 17049550.
      View in: PubMed
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