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Bruce Cree, MD, PhD

TitleAssociate Professor
SchoolUCSF School of Medicine
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-353-2069
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.D.1997 Medicine
    University of California, San FranciscoPh.D.1995 Graduate Division (Biochemistry)
    Collapse Awards and Honors
    UCSF2009Robert B. Layzer Award for Resident Teaching
    National Multiple Sclerosis Society, Northern California Chapter 2006Community Service Award

    Collapse Overview 
    Collapse Overview
    Bruce Cree, MD, PhD, MAS is an Associate Professor of Clinical Neurology in the Department of Neurology at the University of California San Francisco. Dr. Cree completed his MD and PhD in Biochemistry at UCSF. His neurology residency training was at Columbia University. He returned to UCSF for a Sylvia Lawry National Multiple Sclerosis Society fellowship and received a Masters in Advanced Studies in Clinical Research. He is the Clinical Research Director at the UCSF MS Center. He divides his time between patient care, clinical research and teaching. His research focuses on the genetic epidemiology of multiple sclerosis, understanding factors that contribute to disease progression and developing novel therapies for MS through clinical trials. In addition to multiple sclerosis, Dr. Cree specializes in research and care of patients with neuromyelitis optica and transverse myelitis.


    Collapse Research 
    Collapse Research Activities and Funding
    Correlating Multiple Sclerosis Phenotypes with Genotypes
    NIH K23NS048869Aug 19, 2005 - Nov 30, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cree B, Bennett JL, Sheehan M, Cohen J, Hartung HP, Aktas O, Kim HJ, Paul F, Pittock S, Weinshenker B, Wingerchuk D, Fujihara K, Cutter G, Patra K, Flor A, Barron G, Madani S, Ratchford JN, Katz E. Placebo-controlled study in neuromyelitis optica-Ethical and design considerations. Mult Scler. 2016 06; 22(7):862-72. PMID: 26666258.
      View in: PubMed
    2. Cree B. Placebo controlled trials in neuromyelitis optica are needed and ethical. Mult Scler Relat Disord. 2015 Nov; 4(6):536-45. PMID: 26590660.
      View in: PubMed
    3. Cree B. Multiple sclerosis genetics. Handb Clin Neurol. 2014; 122:193-209. PMID: 24507519.
      View in: PubMed
    4. Cree B. Genetics of primary progressive multiple sclerosis. Handb Clin Neurol. 2014; 122:211-30. PMID: 24507520.
      View in: PubMed
    5. Cree B. Acute inflammatory myelopathies. Handb Clin Neurol. 2014; 122:613-67. PMID: 24507538.
      View in: PubMed
    6. Cree B. Update on reproductive safety of current and emerging disease-modifying therapies for multiple sclerosis. Mult Scler. 2013 Jun; 19(7):835-43. PMID: 23319073.
      View in: PubMed
    7. Cree B, Stuart WH, Tornatore CS, Jeffery DR, Pace AL, Cha CH. Efficacy of natalizumab therapy in patients of African descent with relapsing multiple sclerosis: analysis of AFFIRM and SENTINEL data. Arch Neurol. 2011 Apr; 68(4):464-8. PMID: 21482925.
      View in: PubMed
    8. Cree B, Kornyeyeva E, Goodin DS. Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis. Ann Neurol. 2010 Aug; 68(2):145-50. PMID: 20695007.
      View in: PubMed
    9. Cree B, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. PLoS One. 2010 Jun 25; 5(6):e11296. PMID: 20593013.
      View in: PubMed
    10. Cree B, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR. Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. Arch Neurol. 2009 Feb; 66(2):226-33. PMID: 19204159; PMCID: PMC4334456.
      View in: PubMed, PubMed Central
    11. Cree B. Neuromyelitis optica: diagnosis, pathogenesis, and treatment. Curr Neurol Neurosci Rep. 2008 Sep; 8(5):427-33. PMID: 18713580.
      View in: PubMed
    12. Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree B, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24. PMID: 16905561.
      View in: PubMed
    13. Cree B, Bernardini GL, Hays AP, Lowe G. A fatal case of coxsackievirus B4 meningoencephalitis. Arch Neurol. 2003 Jan; 60(1):107-12. PMID: 12533096.
      View in: PubMed
    14. Stüve O, Cree B, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. Neurologist. 2002 Sep; 8(5):290-301. PMID: 12803676.
      View in: PubMed
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