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Caroline Duwaerts, PhD

Title(s)Associate Researcher, Medicine
SchoolSchool of Medicine
EmailCaroline.Duwaerts@ucsf.edu
ORCID ORCID Icon0000-0002-2086-5197 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Loyola University Chicago, Chicago, ILB.S.05/2008Biology & Minor in Chemistry
    Brown University, Providence, RIPh.D.01/2013Medical Sciences: Pathobiology
    University of California, San Francisco, San Francisco, CAPost-Doctoral Fellowship05/2016Hepatology
    Collapse Awards and Honors
    Loyola University Chicago2008  - 2008Excellence in Biological Research Award
    Brown University2009  - 2009Poole Gorham Philanthropy Fellow

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Role of ER Stress in NAFLD Development and Progression
    American Association for the Study of Liver Disease Foundation AASLD Pinnacle Research AwardJul 1, 2019 - Jun 30, 2022
    Role: Principal Investigator
    The Role of Regulated IRE1 Dependent Decay (RIDD) in Endoplasmic Reticulum Stress-Induced Liver Cell Death
    NIH/NIDDK UCSF Liver Center Pilot/Feasibility AwardJun 1, 2018 - May 31, 2019
    Role: Principal Investigator
    Graduate Women in Science - Sigma Delta Epsilon Fellowship Pre-Doctoral FellowshipJun 1, 2012 - May 31, 2013
    Role: Principal Investigator
    NRSA Hepatology Training Grant
    NIH/NIDDK T32DK060414Dec 1, 2001 - Jun 30, 2022
    Role: Trainee 05/06/2013 - 05/05/2016

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sarkar M, Terrault N, Chan W, Cedars MI, Huddleston HG, Duwaerts CC, Balitzer D, Gill RM. Polycystic ovary syndrome (PCOS) is associated with NASH severity and advanced fibrosis. Liver Int. 2019 Oct 18. PMID: 31627243.
      View in: PubMed
    2. Duwaerts CC, Maher JJ. Macronutrients and the Adipose-Liver Axis in Obesity and Fatty Liver. Cell Mol Gastroenterol Hepatol. 2019; 7(4):749-761. PMID: 30763771.
      View in: PubMed
    3. Sarkar M, Terrault N, Duwaerts CC, Tien P, Cedars MI, Huddleston H. The Association of Hispanic Ethnicity with Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome. Curr Opin Gynecol Obstet. 2018 02 20; 1(1):24-33. PMID: 30112518.
      View in: PubMed
    4. Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017; 12(9):e0183912. PMID: 28873429.
      View in: PubMed
    5. Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol. 2017 Sep; 4(2):223-236. PMID: 28649594.
      View in: PubMed
    6. Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury. J Nutr Biochem. 2016 Mar; 29:12-20. PMID: 26895660.
      View in: PubMed
    7. Duwaerts CC, Maher JJ. Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis. Curr Hepatol Rep. 2014 Jun 01; 13(2):119-129. PMID: 25045618.
      View in: PubMed
    8. Duwaerts CC, Sun EP, Cheng CW, van Rooijen N, Gregory SH. Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction. PLoS One. 2013; 8(11):e79702. PMID: 24260285.
      View in: PubMed
    9. Duwaerts CC, Gehring S, Cheng CW, van Rooijen N, Gregory SH. Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury. Liver Int. 2013 Feb; 33(2):255-65. PMID: 23240869.
      View in: PubMed
    10. Lucas LR, Dragisic T, Duwaerts CC, Swiatkowski M, Suzuki H. Effects of recovery from immobilization stress on striatal preprodynorphin- and kappa opioid receptor-mRNA levels of the male rat. Physiol Behav. 2011 Oct 24; 104(5):972-80. PMID: 21723305.
      View in: PubMed
    11. Duwaerts CC, Gregory SH. Targeting the diverse immunological functions expressed by hepatic NKT cells. Expert Opin Ther Targets. 2011 Aug; 15(8):973-88. PMID: 21564001.
      View in: PubMed
    12. Cheng CW, Duwaerts CC, Rooijen Nv, Wintermeyer P, Mott S, Gregory SH. NK cells suppress experimental cholestatic liver injury by an interleukin-6-mediated, Kupffer cell-dependent mechanism. J Hepatol. 2011 Apr; 54(4):746-52. PMID: 21129806.
      View in: PubMed
    13. Aher CV, Duwaerts CC, Akama KT, Lucas LR. Effects of acute diuresis stress on egr-1 (zif268) mRNA levels in brain regions associated with motivated behavior. Brain Res Bull. 2010 Jan 15; 81(1):114-9. PMID: 19835936.
      View in: PubMed
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