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A transcriptional switch governs fibroblast activation in heart disease. Nature. 2021 Jul; 595(7867):438-443.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. PMID: 34163071.
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2 Fields:
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Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. Science. 2021 02 12; 371(6530).
Theodoris CV, Zhou P, Liu L, Zhang Y, Nishino T, Huang Y, Kostina A, Ranade SS, Gifford CA, Uspenskiy V, Malashicheva A, Ding S, Srivastava D. PMID: 33303684.
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8 Fields:
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HumansAnimalsCells
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Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. Nature. 2019 08; 572(7767):120-124.
de Soysa TY, Ranade SS, Okawa S, Ravichandran S, Huang Y, Salunga HT, Schricker A, Del Sol A, Gifford CA, Srivastava D. PMID: 31341279.
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37 Fields:
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Animals
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Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019 07 03; 25(1):87-102.e9.
Stone NR, Gifford CA, Thomas R, Pratt KJB, Samse-Knapp K, Mohamed TMA, Radzinsky EM, Schricker A, Ye L, Yu P, van Bemmel JG, Ivey KN, Pollard KS, Srivastava D. PMID: 31271750.
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20 Fields:
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AnimalsCells
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Oligogenic inheritance of a human heart disease involving a genetic modifier. Science. 2019 05 31; 364(6443):865-870.
Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D. PMID: 31147515.
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37 Fields:
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Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nat Genet. 2018 02; 50(2):250-258.
Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. PMID: 29358654.
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47 Fields:
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HumansCells
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Differentiation of V2a interneurons from human pluripotent stem cells. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):4969-4974.
Butts JC, McCreedy DA, Martinez-Vargas JA, Mendoza-Camacho FN, Hookway TA, Gifford CA, Taneja P, Noble-Haeusslein L, McDevitt TC. PMID: 28438991.
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16 Fields:
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HumansCells
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Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports. 2016 11 08; 7(5):983-997.
Aguilar CA, Pop R, Shcherbina A, Watts A, Matheny RW, Cacchiarelli D, Han WM, Shin E, Nakhai SA, Jang YC, Carrigan CT, Gifford CA, Kottke MA, Cesana M, Lee J, Urso ML, Meissner A. PMID: 27773702.
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13 Fields:
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AnimalsCells
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Heart disease modelling adds a Notch to its belt. Nat Cell Biol. 2016 Jan; 18(1):3-5.
Gifford CA, Srivastava D. PMID: 26693916.
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2 Fields:
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Humans
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A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells. Nat Biotechnol. 2015 Nov; 33(11):1182-92.
Tsankov AM, Akopian V, Pop R, Chetty S, Gifford CA, Daheron L, Tsankova NM, Meissner A. PMID: 26501952.
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46 Fields:
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In vivo Monitoring of Transcriptional Dynamics After Lower-Limb Muscle Injury Enables Quantitative Classification of Healing. Sci Rep. 2015 Sep 18; 5:13885.
Aguilar CA, Shcherbina A, Ricke DO, Pop R, Carrigan CT, Gifford CA, Urso ML, Kottke MA, Meissner A. PMID: 26381351.
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9 Fields:
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AnimalsCells
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Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency. Cell. 2015 Jul 16; 162(2):412-424.
Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, Mikkelsen TS. PMID: 26186193.
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82 Fields:
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Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet. 2015 May; 47(5):469-78.
Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A. PMID: 25822089.
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160 Fields:
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Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 2015 Feb 19; 518(7539):355-359.
Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cachiarelli D, Tsankov A, Epstein C, Rinn JR, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A. PMID: 25533951.
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80 Fields:
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Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell. 2013 May 23; 153(5):1149-63.
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A. PMID: 23664763.
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202 Fields:
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Epigenetic obstacles encountered by transcription factors: reprogramming against all odds. Curr Opin Genet Dev. 2012 Oct; 22(5):409-15.
Gifford CA, Meissner A. PMID: 22922161.
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15 Fields:
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HumansAnimals
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Epigenomics and chromatin dynamics. Genome Biol. 2012 Feb 24; 13(2):313.
Akopian V, Chan MM, Clement K, Galonska C, Gifford CA, Lehtola E, Liao J, Samavarchi-Tehrani P, Sindhu C, Smith ZD, Tsankov AM, Webster J, Zhang Y, Ziller MJ, Meissner A. PMID: 22364154.
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2 Fields:
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HumansAnimalsCells
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Epigenomics and chromatin dynamics. Genome Biology. 2012 Jan 1; 13(2):313.
Akopian AV, Chan CM, Clement CK, Galonska GC, Gifford GC, Lehtola LE, Liao LJ, Samavarchi-Tehrani SP, Sindhu SC, Smith SZ, Tsankov TA, Webster WJ, Zhang ZY, Ziller ZM, Meissner MA. .
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Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa. Nat Cell Biol. 2007 Jul; 9(7):797-803.
Mougous JD, Gifford CA, Ramsdell TL, Mekalanos JJ. PMID: 17558395.
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138 Fields:
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Cells
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A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Science. 2006 Jun 09; 312(5779):1526-30.
Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, Gifford CA, Goodman AL, Joachimiak G, Ordoñez CL, Lory S, Walz T, Joachimiak A, Mekalanos JJ. PMID: 16763151.
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455 Fields:
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HumansAnimalsCells