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Chengcheng Zhu, PhD

Title(s)Assistant Researcher, Radiology
SchoolSchool of Medicine
Phone415-221-4810 ext. 3818
ORCID ORCID Icon0000-0001-6898-549X Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Cambridge, United KingdomPh.D.2013Radiology
    University of Cambridge, United KingdomMPhil2010Radiology
    Peking University, Beijing, ChinaB.Sc.2009Electronics
    Collapse Awards and Honors
    Department of Radiology and Biomedical Imaging, UCSF2019Margaret Hart Surbeck Travel Award
    Society for Cardiovascular MR2019Regional Travel Award
    Department of Radiology and Biomedical Imaging, UCSF2018Bruce Hasegawa Award
    International Society for Magnetic Resonance in Medicine2018Magna Cum Laude Merit Award
    National Heart, Lung, and Blood Institute2017Career Development Award (K99/R00)
    International Society for Magnetic Resonance in Medicine2017Junior Fellow
    International Society for Magnetic Resonance in Medicine2016  - 2017Summa Cum Laude Merit Awards (five times)
    Society of Magnetic Resonance Anigography2014  - 2019Travel Award (three times)
    Journal of Magnetic Resonance Imaging 2016Distinguished Reviewer
    International Society for Magnetic Resonance in Medicine2011  - 2014Trainee Stipend (three times)
    Great Britain-China Educational Trust2011Outstanding Scholar Award

    Collapse Overview 
    Collapse Overview
    Chengcheng Zhu, PhD, is an Assistant Professional Researcher in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He obtained his BS in Electronics from Peking University in China in 2009, followed by his MPhil and PhD in Radiology from University of Cambridge in 2010 and 2013. In January 2014, Dr. Zhu joined UCSF’s Cardiovascular Imaging Research Interest Group at VA Medical Center.

    Collapse Research 
    Collapse Research Activities and Funding
    Characterization of intracranial vessel wall morphology and inflammation using 3D high resolution MRI
    NIH/NHLBI K99HL136883May 1, 2017 - Apr 30, 2019
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Rutland JW, Delman BN, Gill CM, Zhu C, Shrivastava RK, Balchandani P. Emerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future Directions. AJNR Am J Neuroradiol. 2019 Dec 26. PMID: 31879330.
      View in: PubMed
    2. Ran Y, Wang Y, Zhu M, Wu X, Malhotra A, Lei X, Zhang F, Wang X, Xie S, Zhou J, Zhu J, Cheng J, Zhu C. Higher Plaque Burden of Middle Cerebral Artery Is Associated With Recurrent Ischemic Stroke: A Quantitative Magnetic Resonance Imaging Study. Stroke. 2019 Dec 20; STROKEAHA119028405. PMID: 31856694.
      View in: PubMed
    3. Zhu C, Cao L, Wen Z, Ahn S, Raithel E, Forman C, Hope M, Saloner D. Surveillance of abdominal aortic aneurysm using accelerated 3D non-contrast black-blood cardiovascular magnetic resonance with compressed sensing (CS-DANTE-SPACE). J Cardiovasc Magn Reson. 2019 Oct 28; 21(1):66. PMID: 31660983.
      View in: PubMed
    4. Leach J, Kao E, Zhu C, Saloner D, Hope MD. On the relative impact of intraluminal thrombus heterogeneity on abdominal aortic aneurysm mechanics. J Biomech Eng. 2019 Jun 29. PMID: 31253989.
      View in: PubMed
    5. Wang Y, Liu X, Wu X, Degnan AJ, Malhotra A, Zhu C. Culprit intracranial plaque without substantial stenosis in acute ischemic stroke on vessel wall MRI: A systematic review. Atherosclerosis. 2019 Aug; 287:112-121. PMID: 31254918.
      View in: PubMed
    6. Liu X, Zhang Z, Zhu C, Feng J, Liu P, Kong Q, Zhang X, Zhang Q, Jin H, Ge H, Jiang Y, Saloner D, Li Y. Wall enhancement of intracranial saccular and fusiform aneurysms may differ in intensity and extension: a pilot study using 7-T high-resolution black-blood MRI. Eur Radiol. 2020 Jan; 30(1):301-307. PMID: 31218429.
      View in: PubMed
    7. Zhu C, Wang X, Eisenmenger L, Tian B, Liu Q, Degnan AJ, Hess C, Saloner D, Lu J. Surveillance of Unruptured Intracranial Saccular Aneurysms Using Noncontrast 3D-Black-Blood MRI: Comparison of 3D-TOF and Contrast-Enhanced MRA with 3D-DSA. AJNR Am J Neuroradiol. 2019 Jun; 40(6):960-966. PMID: 31122914.
      View in: PubMed
    8. JOSEPH R. LEACH, CHENGCHENG ZHU, DAVID SALONER, MICHAEL D. HOPE. COMPARISON OF TWO METHODS FOR ESTIMATING THE UNLOADED STATE FOR ABDOMINAL AORTIC ANEURYSM STRESS CALCULATIONS. Journal of Mechanics in Medicine and Biology. 2019 May 1; 19(03):1950015.
      View in: Publisher Site
    9. Zhu C, Leach JR, Tian B, Cao L, Wen Z, Wang Y, Liu X, Liu Q, Lu J, Saloner D, Hope MD. Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI. J Magn Reson Imaging. 2019 Sep; 50(3):994-1001. PMID: 30694008.
      View in: PubMed
    10. Zhu C, Tian X, Degnan AJ, Lu J, Liu Q. Reply. AJNR Am J Neuroradiol. 2019 01; 40(1):E2. PMID: 30442701.
      View in: PubMed
    11. Tian B, Toossi S, Eisenmenger L, Faraji F, Ballweber MK, Josephson SA, Haraldsson H, Zhu C, Ahn S, Laub G, Hess C, Saloner D. Visualizing wall enhancement over time in unruptured intracranial aneurysms using 3D vessel wall imaging. J Magn Reson Imaging. 2019 Jul; 50(1):193-200. PMID: 30390363.
      View in: PubMed
    12. Tian B, Liu Q, Wang X, Chen S, Xu B, Zhu C, Lu J. Chronic intracranial artery stenosis: Comparison of whole-brain arterial spin labeling with CT perfusion. Clin Imaging. 2018 Nov - Dec; 52:252-259. PMID: 30170275.
      View in: PubMed
    13. Wang X, Zhu C, Li J, Degnan AJ, Jiang T, Lu J. Knowledge-based iterative model reconstruction: Comparative image quality with low tube voltage cerebral CT angiography. Medicine (Baltimore). 2018 Jul; 97(30):e11514. PMID: 30045274.
      View in: PubMed
    14. Wang X, Zhu C, Leng Y, Degnan AJ, Lu J. Intracranial Aneurysm Wall Enhancement Associated with Aneurysm Rupture: A Systematic Review and Meta-analysis. Acad Radiol. 2019 May; 26(5):664-673. PMID: 29908979.
      View in: PubMed
    15. Zhu C, Wang X, Degnan AJ, Shi Z, Tian B, Liu Q, Hess C, Saloner D, Lu J. Wall enhancement of intracranial unruptured aneurysm is associated with increased rupture risk and traditional risk factors. Eur Radiol. 2018 Dec; 28(12):5019-5026. PMID: 29872913.
      View in: PubMed
    16. Zhu C, Tian X, Degnan AJ, Shi Z, Zhang X, Chen L, Teng Z, Saloner D, Lu J, Liu Q. Clinical Significance of Intraplaque Hemorrhage in Low- and High-Grade Basilar Artery Stenosis on High-Resolution MRI. AJNR Am J Neuroradiol. 2018 07; 39(7):1286-1292. PMID: 29794236.
      View in: PubMed
    17. Shi Z, Zhu C, Degnan AJ, Tian X, Li J, Chen L, Zhang X, Peng W, Chen C, Lu J, Jiang T, Saloner D, Liu Q. Identification of high-risk plaque features in intracranial atherosclerosis: initial experience using a radiomic approach. Eur Radiol. 2018 Sep; 28(9):3912-3921. PMID: 29633002.
      View in: PubMed
    18. Zhu C, Kallianos K, Henry T, Hope MD. Ferumoxtyol-enhanced MR Angiography for Transcatheter Aortic Valve Replacement Planning in Patients with Renal Failure. Radiology. 2018 04; 287(1):362-363. PMID: 29558308.
      View in: PubMed
    19. Zhu C, Saloner D, Hope MD. Letter by Zhu et al Regarding Article, "Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair". Circulation. 2018 03 20; 137(12):1293-1294. PMID: 29555713.
      View in: PubMed
    20. Zhu C, Tian B, Chen L, Eisenmenger L, Raithel E, Forman C, Ahn S, Laub G, Liu Q, Lu J, Liu J, Hess C, Saloner D. Accelerated whole brain intracranial vessel wall imaging using black blood fast spin echo with compressed sensing (CS-SPACE). MAGMA. 2018 Jun; 31(3):457-467. PMID: 29209856.
      View in: PubMed
    21. Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2018 Mar; 34(3):475-483. PMID: 28905233.
      View in: PubMed
    22. Liu J, Koskas L, Faraji F, Kao E, Wang Y, Haraldsson H, Kefayati S, Zhu C, Ahn S, Laub G, Saloner D. Highly accelerated intracranial 4D flow MRI: evaluation of healthy volunteers and patients with intracranial aneurysms. MAGMA. 2018 Apr; 31(2):295-307. PMID: 28785850.
      View in: PubMed
    23. Jiang Y, Peng W, Tian B, Zhu C, Chen L, Wang X, Liu Q, Wang Y, Xiang Z, Degnan AJ, Teng Z, Saloner D, Lu J. Identification and Quantitative Assessment of Different Components of Intracranial Atherosclerotic Plaque by Ex Vivo 3T High-Resolution Multicontrast MRI. AJNR Am J Neuroradiol. 2017 Sep; 38(9):1716-1722. PMID: 28684455.
      View in: PubMed
    24. Wang Y, Seguro F, Kao E, Zhang Y, Faraji F, Zhu C, Haraldsson H, Hope M, Saloner D, Liu J. Segmentation of lumen and outer wall of abdominal aortic aneurysms from 3D black-blood MRI with a registration based geodesic active contour model. Med Image Anal. 2017 Aug; 40:1-10. PMID: 28549310.
      View in: PubMed
    25. Ma C, Guo X, Liu L, Zhan Q, Li J, Zhu C, Wang L, Zhang J, Fang X, Qu J, Chen S, Shao C, Lu JP. Effect of region of interest size on ADC measurements in pancreatic adenocarcinoma. Cancer Imaging. 2017 May 02; 17(1):13. PMID: 28464866.
      View in: PubMed
    26. Lin JM, Patterson AJ, Chao TC, Zhu C, Chang HC, Mendes J, Chung HW, Gillard JH, Graves MJ. Free-breathing black-blood CINE fast-spin echo imaging for measuring abdominal aortic wall distensibility: a feasibility study. Phys Med Biol. 2017 05 21; 62(10):N204-N218. PMID: 28327475.
      View in: PubMed
    27. Liu J, Feng L, Shen HW, Zhu C, Wang Y, Mukai K, Brooks GC, Ordovas K, Saloner D. Highly-accelerated self-gated free-breathing 3D cardiac cine MRI: validation in assessment of left ventricular function. MAGMA. 2017 Aug; 30(4):337-346. PMID: 28120280.
      View in: PubMed
    28. Zhu C, Tian B, Leach JR, Liu Q, Lu J, Chen L, Saloner D, Hope MD. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography. Eur Radiol. 2017 May; 27(5):1787-1794. PMID: 27553926.
      View in: PubMed
    29. Jiang Y, Zhu C, Peng W, Degnan AJ, Chen L, Wang X, Liu Q, Wang Y, Xiang Z, Teng Z, Saloner D, Lu J. Ex-vivo imaging and plaque type classification of intracranial atherosclerotic plaque using high resolution MRI. Atherosclerosis. 2016 06; 249:10-6. PMID: 27062404.
      View in: PubMed
    30. Zhu C, Haraldsson H, Tian B, Meisel K, Ko N, Lawton M, Grinstead J, Ahn S, Laub G, Hess C, Saloner D. High resolution imaging of the intracranial vessel wall at 3 and 7 T using 3D fast spin echo MRI. MAGMA. 2016 Jun; 29(3):559-70. PMID: 26946509.
      View in: PubMed
    31. Zhu C, Graves MJ, Sadat U, Young VE, Gillard JH, Patterson AJ. Comparison of Gated and Ungated Black-Blood Fast Spin-echo MRI of Carotid Vessel Wall at 3T. Magn Reson Med Sci. 2016 Jul 11; 15(3):266-72. PMID: 26549163.
      View in: PubMed
    32. Zhu C, Haraldsson H, Faraji F, Owens C, Gasper W, Ahn S, Liu J, Laub G, Hope MD, Saloner D. Isotropic 3D black blood MRI of abdominal aortic aneurysm wall and intraluminal thrombus. Magn Reson Imaging. 2016 Jan; 34(1):18-25. PMID: 26471514.
      View in: PubMed
    33. Zhang X, Zhu C, Peng W, Tian B, Chen L, Teng Z, Lu J, Sadat U, Saloner D, Liu Q. Scan-Rescan Reproducibility of High Resolution Magnetic Resonance Imaging of Atherosclerotic Plaque in the Middle Cerebral Artery. PLoS One. 2015; 10(8):e0134913. PMID: 26247869.
      View in: PubMed
    34. Hope MD, Hope TA, Zhu C, Faraji F, Haraldsson H, Ordovas KG, Saloner D. Vascular Imaging With Ferumoxytol as a Contrast Agent. AJR Am J Roentgenol. 2015 Sep; 205(3):W366-73. PMID: 26102308.
      View in: PubMed
    35. Graves MJ, Zhu C.. 3D Imaging Technologies in Atherosclerosis. (Editors: Trivedi R., Saba L., Suri J.). Basic Principles of Magnetic Resonance Imaging. 2015.
      View Publication
    36. Zhu C, Graves MJ, Yuan J, Sadat U, Gillard JH, Patterson AJ. Optimization of improved motion-sensitized driven-equilibrium (iMSDE) blood suppression for carotid artery wall imaging. J Cardiovasc Magn Reson. 2014 Aug 09; 16:61. PMID: 25160911.
      View in: PubMed
    37. Zhu C, Sadat U, Patterson AJ, Teng Z, Gillard JH, Graves MJ. 3D high-resolution contrast enhanced MRI of carotid atheroma--a technical update. Magn Reson Imaging. 2014 Jun; 32(5):594-7. PMID: 24630443.
      View in: PubMed
    38. Zhu C, Wood NB, Xu XY, Gillard JH.Quantification of Shear Stress and Geometric Risk Factors in Carotid Atherosclerosis: Review and Clinical Evidence. Recent Patents on Medical Imaging. 2013; 3(1):27-43.
    39. Zhu C, Patterson AJ, Thomas OM, Sadat U, Graves MJ, Gillard JH. Carotid stenosis assessment with multi-detector CT angiography: comparison between manual and automatic segmentation methods. Int J Cardiovasc Imaging. 2013 Apr; 29(4):899-905. PMID: 23135615.
      View in: PubMed
    40. Teng Z, Sadat U, Ji G, Zhu C, Young VE, Graves MJ, Gillard JH. Lumen irregularity dominates the relationship between mechanical stress condition, fibrous-cap thickness, and lumen curvature in carotid atherosclerotic plaque. J Biomech Eng. 2011 Mar; 133(3):034501. PMID: 21303186.
      View in: PubMed
    41. Zhu C, Teng Z, Sadat U, Young VE, Graves MJ, Li ZY, Gillard JH. Normalized wall index specific and MRI-based stress analysis of atherosclerotic carotid plaques: a study comparing acutely symptomatic and asymptomatic patients. Circ J. 2010 Nov; 74(11):2360-4. PMID: 20834184.
      View in: PubMed
    42. Sadat U, Teng Z, Young VE, Zhu C, Tang TY, Graves MJ, Gillard JH. Impact of plaque haemorrhage and its age on structural stresses in atherosclerotic plaques of patients with carotid artery disease: an MR imaging-based finite element simulation study. Int J Cardiovasc Imaging. 2011 Mar; 27(3):397-402. PMID: 20700655.
      View in: PubMed
    43. Teng Z, Sadat U, Li Z, Huang X, Zhu C, Young VE, Graves MJ, Gillard JH. Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: an in vivo MRI-based 2D finite-element study. Ann Biomed Eng. 2010 Oct; 38(10):3096-101. PMID: 20499180.
      View in: PubMed
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