Chengyu Deng, PhD

Title(s)Postdoctoral Scholar, Bioengineering
SchoolSchool of Pharmacy
Address1550 Fourth Street, #581
San Francisco CA 94158
Emailchengyu.deng@ucsf.edu
ORCID ORCID Icon0000-0003-3595-9935 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Virginia TechPhD12/2020Microfluidic Epigenomics
    South China University of TechnologyBS07/2015Chemical Engineering
    Collapse Awards and Honors
    UCSF2023  - 2025Weill Neurohub Fellowship Award
    SCUT2014  - 2015Dow Chemical Company Scholarship
    SCUT2012  - 2014National Scholarship
    SCUT2012  - 2014Excellent leaders of SCUT

    Collapse Overview 
    Collapse Overview
    I am an epigenomics researcher with expertise in functional genomics and molecular neuroscience. My research is focused on understanding how genomic, epigenomic, and environmental factors interact to influence neurodegeneration, inflammation, and aging.

    Collapse Research 
    Collapse Research Activities and Funding
    Functional characterization of differentially methylated regions in Alzheimer’s diseases.
    Weill Neurohub Fellowship Awards Sep 1, 2023 - Aug 31, 2025
    Description: This proposal aims to characterize the functional impact of AD-associated differential DNA methylation using MPRA and CRISPR screening in microglia, astrocytes and neurons. This fellowship includes support in the amount of $75,000 per year for two years.

    Collapse ORNG Applications 
    Collapse Featured Publications

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    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Massively parallel characterization of regulatory elements in the developing human cortex. Science. 2024 May 24; 384(6698):eadh0559. Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, PsychENCODE Consortium‡, Pollen AA, Nowakowski TJ, Ahituv N, Pollard KS, PsychENCODE Consortium. PMID: 38781390.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia. Elife. 2024 Apr 22; 12. Zhu B, Ainsworth RI, Wang Z, Liu Z, Sierra S, Deng C, Callado LF, Meana JJ, Wang W, Lu C, González-Maeso J. PMID: 38648100; PMCID: PMC11034945.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Epigenomic tomography for probing spatially defined chromatin state in the brain. Cell Rep Methods. 2024 Mar 25; 4(3):100738. Liu Z, Deng C, Zhou Z, Xiao Y, Jiang S, Zhu B, Naler LB, Jia X, Yao DD, Lu C. PMID: 38508188; PMCID: PMC10985265.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Three-dimensional genome rewiring in loci with human accelerated regions. Science. 2023 04 28; 380(6643):eabm1696. Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Zoonomia Consortium§, Nowakowski T, Ahituv N, Pollen A, Pollard KS. PMID: 37104607; PMCID: PMC10999243.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    5. Transcription factor binding site orientation and order are major drivers of gene regulatory activity. Nat Commun. 2023 04 22; 14(1):2333. Georgakopoulos-Soares I, Deng C, Agarwal V, Chan CSY, Zhao J, Inoue F, Ahituv N. PMID: 37087538; PMCID: PMC10122648.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    6. Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases. bioRxiv. 2023 Mar 02. Zeng B, Bendl J, Deng C, Lee D, Misir R, Reach SM, Kleopoulos SP, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE, Roussos P. PMID: 37090548; PMCID: PMC10120699.
      View in: PubMed   Mentions:
    7. Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex. bioRxiv. 2023 Feb 16. Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, Pollen A, Nowakowski TJ, Ahituv N, Pollard KS. PMID: 36824845; PMCID: PMC9949039.
      View in: PubMed   Mentions:
    8. nMOWChIP-seq: low-input genome-wide mapping of non-histone targets. NAR Genom Bioinform. 2022 Jun; 4(2):lqac030. Liu Z, Naler LB, Zhu Y, Deng C, Zhang Q, Zhu B, Zhou Z, Sarma M, Murray A, Xie H, Lu C. PMID: 35402909; PMCID: PMC8988714.
      View in: PubMed   Mentions: 2  
    9. Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. Nat Commun. 2022 03 21; 13(1):1504. Kreimer A, Ashuach T, Inoue F, Khodaverdian A, Deng C, Yosef N, Ahituv N. PMID: 35315433; PMCID: PMC8938438.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    10. Multiplexed and Ultralow-Input ChIP-seq Enabled by Tagmentation-Based Indexing and Facile Microfluidics. Anal Chem. 2020 10 20; 92(20):13661-13666. Deng C, Murphy TW, Zhang Q, Naler LB, Xu A, Lu C. PMID: 32957776; PMCID: PMC7578044.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Microfluidic epigenomic mapping technologies for precision medicine. Lab Chip. 2019 08 21; 19(16):2630-2650. Deng C, Naler LB, Lu C. PMID: 31338502; PMCID: PMC6697104.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    12. Effects of culture condition on epigenomic profiles of brain tumor cells. ACS Biomater Sci Eng. 2019 Mar 11; 5(3):1544-1552. Cox MC, Deng C, Naler LB, Lu C, Verbridge SS. PMID: 31799379; PMCID: PMC6886720.
      View in: PubMed   Mentions: 8     Fields:    
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