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Christopher Hess, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentRadiology
Address505 Parnassus Avenue
San Francisco CA 94143
Phone415-476-1573
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2008Neuroradiology
    University of California, San FranciscoResidency2007Radiology
    University of IllinoisM.D.2002School of Medicine
    University of IllinoisPh.D.1999Electrical Engineering
    Collapse Awards and Honors
    University of California, San Francisco2007Elmer Ng Award for Outstanding Resident in Radiology
    American Society of Neuroradiology2006Best Paper Award in Functional Neuroradiology
    American Society of Neuroradiology2005Berlex Best Paper Award, General Neuroradiology
    Alpha Chapter, University of Illinois2000Alpha Omega Alpha
    1990Eta Kappa Nu

    Collapse Overview 
    Collapse Overview
    Christopher Hess, MD, PhD, is the Alexander R. Margulis Distinguished Professor and Chair of the Department of Radiology and Biomedical Imaging at UCSF.

    Dr. Hess completed his PhD in Electrical Engineering and his MD at the University of Illinois in 1998 and 2002, respectively. He was in the first class of NIH T32 radiology research program at UCSF in 2005-2006. He served as chief resident in Radiology from 2006-2007 and was the recipient of the RSNA's Roentgen Award in 2006 and the department's Elmer Ng Award for outstanding resident in 2007. After completing residency in 2007, he remained at UCSF and went on to complete his fellowship training in Neuroradiology the following year. He joined the UCSF faculty in the same year. After serving as Chief of Neuroradiology at the San Francisco VA, Fellowship Director for Neuroradiology at UCSF, and Chief of Neuroradiology at UCSF, he become the Chair of the Department of Radiology and Biomedical Imaging in 2018.

    Dr. Hess’s research interests lie in the translational application of MR imaging techniques to vascular disease, brain development and degeneration, and epilepsy, especially using diffusion imaging and ultra-high-field MRI. He is a fellow of the American Institute for Medical and Biological Engineering, and serves on the editorial board of Radiology and the American Journal of Neuroradiology.

    Expertise: Neuroradiology

    Specialty: Neurodegenerative disorders, epilepsy, vascular disease

    Professional Interests: Neurodegenerative disorders, epilepsy, vascular disease, image-guided spine interventions, diffusion MRI and fiber tractography, ultra-high field brain MRI, quantitative MRI

    Education and Training:
    • Medical School: University of Illinois, Urbana, IL, MD (1998-2002)
    • Internship: California Pacific Medical Center, San Francisco - Internal Medicine (2002-2003)
    • Residency: University of California, San Francisco - Radiology (2003-2007)
    • Chief Residency: University of California, San Francisco - Chief Resident, Radiology (2006-2007)
    • Fellowship: University of California, San Francisco - Neuroradiology (2007-2008)
    • Board Certifications: Medical Licensure, California (2004)
    • Board Certifications: American Board of Radiology (2007)
    • Fluoroscopy Supervisor and Operator, California Department of Public Health (2007)
    • Subspecialty Certification, Neuroradiology, American Board of Radiology (2009)


    Collapse Research 
    Collapse Research Activities and Funding
    IMPROVED MONITORING OF PREMANIFEST AND EARLY HUNTINGTONS USING 7T MULTIMODAL MRI
    NIH/NINDS R01NS099564Jul 1, 2017 - Jun 30, 2022
    Role: Co-Principal Investigator
    Towards Baby Brain Connectome: a Study of Newborn Brain Networks
    NIH/NICHD R01HD072074Jan 4, 2013 - Nov 30, 2017
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Wintermark M, Lee Y, Kerr A, Hess C, Dillon WP, Mukherji SK, Norbash A, Seidenwurm D, Law M. Impact of Neuroradiology Staffing on Academic Hospital Level Quality and Cost Measures for the Neuroscience Service Line. J Am Coll Radiol. 2018 Jul 26. PMID: 30057242.
      View in: PubMed
    2. Zhu C, Wang X, Degnan AJ, Shi Z, Tian B, Liu Q, Hess C, Saloner D, Lu J. Wall enhancement of intracranial unruptured aneurysm is associated with increased rupture risk and traditional risk factors. Eur Radiol. 2018 Jun 05. PMID: 29872913.
      View in: PubMed
    3. Wu CX, Ma L, Chen XZ, Chen XL, Chen Y, Zhao YL, Hess C, Kim H, Jin HW, Ma J. Evaluation of Angioarchitectural Features of Unruptured Brain Arteriovenous Malformation by Susceptibility Weighted Image (SWI). World Neurosurg. 2018 May 30. PMID: 29859363.
      View in: PubMed
    4. Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess C, Sugrue LP, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS. CXCR4 involvement in neurodegenerative diseases. Transl Psychiatry. 2018 Apr 11; 8(1):73. PMID: 29636460.
      View in: PubMed
    5. Karch CM, Wen N, Fan CC, Yokoyama JS, Kouri N, Ross OA, Höglinger G, Müller U, Ferrari R, Hardy J, Schellenberg GD, Sleiman PM, Momeni P, Hess C, Miller BL, Sharma M, Van Deerlin V, Smeland OB, Andreassen OA, Dale AM, Desikan RS. Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum. JAMA Neurol. 2018 Apr 09. PMID: 29630712.
      View in: PubMed
    6. Nordstrom M, Felton E, Sear K, Tamrazi B, Torkildson J, Gauvain K, Haas-Kogan DA, Chen J, Buono BD, Banerjee A, Samuel D, Saloner D, Tian B, Roddy E, Hess C, Fullerton H, Mueller S. Large Vessel Arteriopathy After Cranial Radiation Therapy in Pediatric Brain Tumor Survivors. J Child Neurol. 2018 Apr; 33(5):359-366. PMID: 29575995.
      View in: PubMed
    7. Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess C, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagic A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E. Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. Epilepsia. 2018 Mar 30. PMID: 29600809.
      View in: PubMed
    8. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 Jan; 15(1):e1002504. PMID: 29377952.
      View in: PubMed
    9. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 01; 15(1):e1002487. PMID: 29315334.
      View in: PubMed
    10. Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess C, Rosen HJ, Geschwind MD. Neuroimaging in Dementia. Semin Neurol. 2017 Oct; 37(5):510-537. PMID: 29207412.
      View in: PubMed
    11. Zhu C, Tian B, Chen L, Eisenmenger L, Raithel E, Forman C, Ahn S, Laub G, Liu Q, Lu J, Liu J, Hess C, Saloner D. Accelerated whole brain intracranial vessel wall imaging using black blood fast spin echo with compressed sensing (CS-SPACE). MAGMA. 2017 Dec 05. PMID: 29209856.
      View in: PubMed
    12. Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess C, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 Jan; 135(1):85-93. PMID: 29177679.
      View in: PubMed
    13. Steiner JE, McCoy GN, Hess C, Dobyns WB, Metry DW, Drolet BA, Maheshwari M, Siegel DH. Structural malformations of the brain, eye, and pituitary gland in PHACE syndrome. Am J Med Genet A. 2018 Jan; 176(1):48-55. PMID: 29171184.
      View in: PubMed
    14. Kim H, Kim JH, Possin KL, Winer J, Geschwind MD, Xu D, Hess C. Surface-based morphometry reveals caudate subnuclear structural damage in patients with premotor Huntington disease. Brain Imaging Behav. 2017 Oct; 11(5):1365-1372. PMID: 27730480.
      View in: PubMed
    15. Tan CH, Hyman BT, Tan JJX, Hess C, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Polygenic hazard scores in preclinical Alzheimer disease. Ann Neurol. 2017 Sep; 82(3):484-488. PMID: 28940650.
      View in: PubMed
    16. Chen X, Cooke DL, Saloner D, Nelson J, Su H, Lawton MT, Hess C, Tihan T, Zhao Y, Kim H. Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages. Stroke. 2017 10; 48(10):2881-2884. PMID: 28855391.
      View in: PubMed
    17. Wahl M, Anwar M, Hess C, Chang SM, Lupo JM. Relationship between radiation dose and microbleed formation in patients with malignant glioma. Radiat Oncol. 2017 Aug 10; 12(1):126. PMID: 28797254.
      View in: PubMed
    18. Mamlouk MD, Nicholson AD, Cooke DL, Hess C. Diffusion-weighted imaging for cutaneous vascular anomalies. Clin Imaging. 2017 Nov - Dec; 46:121-122. PMID: 28768597.
      View in: PubMed
    19. Mamlouk MD, Maheshwari M, Burrows PE, Siegel DH, Frieden IJ, Drolet BA, Hess C. PHACE syndrome and cerebral cavernous malformations: association or simply microhemorrhages? Childs Nerv Syst. 2017 Sep; 33(9):1421-1422. PMID: 28623519.
      View in: PubMed
    20. Mamlouk MD, Nicholson AD, Cooke DL, Hess C. Tips and tricks to optimize MRI protocols for cutaneous vascular anomalies. Clin Imaging. 2017 Sep - Oct; 45:71-80. PMID: 28622551.
      View in: PubMed
    21. Zou X, Hart BL, Mabray M, Bartlett MR, Bian W, Nelson J, Morrison LA, McCulloch CE, Hess C, Lupo JM, Kim H. Automated algorithm for counting microbleeds in patients with familial cerebral cavernous malformations. Neuroradiology. 2017 Jul; 59(7):685-690. PMID: 28534135.
      View in: PubMed
    22. Possin KL, Kim H, Geschwind MD, Moskowitz T, Johnson ET, Sha SJ, Apple A, Xu D, Miller BL, Finkbeiner S, Hess C, Kramer JH. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 2017 Jul 01; 101:57-64. PMID: 28427989.
      View in: PubMed
    23. Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess C, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 Mar; 14(3):e1002258. PMID: 28323831.
      View in: PubMed
    24. Patterson A, Okun MS, Hess C. High-voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy. Tremor Other Hyperkinet Mov (N Y). 2017; 7:449. PMID: 28373925.
      View in: PubMed
    25. Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J. Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol. 2017 May; 133(5):825-837. PMID: 28271184.
      View in: PubMed
    26. Whitman IR, Gladstone RA, Badhwar N, Hsia HH, Lee BK, Josephson SA, Meisel KM, Dillon WP, Hess C, Gerstenfeld EP, Marcus GM. Brain Emboli After Left Ventricular Endocardial Ablation. Circulation. 2017 Feb 28; 135(9):867-877. PMID: 28119381.
      View in: PubMed
    27. Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):152-164. PMID: 27899424.
      View in: PubMed
    28. Ziu M, Dunn IF, Hess C, Fleseriu M, Bodach ME, Tumialan LM, Oyesiku NM, Patel KS, Wang R, Carter BS, Chen JY, Chen CC, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Posttreatment Follow-up Evaluation of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 10; 79(4):E541-3. PMID: 27635964.
      View in: PubMed
    29. Chen CC, Carter BS, Wang R, Patel KS, Hess C, Bodach ME, Tumialan LM, Oyesiku NM, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Preoperative Imaging Assessment of Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 10; 79(4):E524-6. PMID: 27635958.
      View in: PubMed
    30. Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess C, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA. PHACE Syndrome: Consensus-Derived Diagnosis and Care Recommendations. J Pediatr. 2016 Nov; 178:24-33.e2. PMID: 27659028.
      View in: PubMed
    31. Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess C, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Age-dependent effects of APOE e4 in preclinical Alzheimer's disease. Ann Clin Transl Neurol. 2016 Sep; 3(9):668-77. PMID: 27648456.
      View in: PubMed
    32. Garcia MA, Lazar A, Duriseti S, Raleigh DR, Hess C, Fogh SE, Barani IJ, Nakamura JL, Larson DA, Theodosopoulos P, McDermott M, Sneed PK, Braunstein S. Discovery of additional brain metastases on the day of stereotactic radiosurgery: risk factors and outcomes. J Neurosurg. 2017 Jun; 126(6):1756-1763. PMID: 27367235.
      View in: PubMed
    33. Mamlouk MD, Hess C. Arterial spin-labeled perfusion for vascular anomalies in the pediatric head and neck. Clin Imaging. 2016 Sep-Oct; 40(5):1040-6. PMID: 27372212.
      View in: PubMed
    34. Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess C, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 Jun 01; 73(6):691-7. PMID: 27088644.
      View in: PubMed
    35. Kansagra AP, Mabray MC, Ferriero DM, Barkovich AJ, Xu D, Hess C. Microstructural maturation of white matter tracts in encephalopathic neonates. Clin Imaging. 2016 Sep-Oct; 40(5):1009-13. PMID: 27314214; PMCID: PMC5010966 [Available on 09/01/17].
    36. Kim H, Lepage C, Maheshwary R, Jeon S, Evans AC, Hess C, Barkovich AJ, Xu D. NEOCIVET: Towards accurate morphometry of neonatal gyrification and clinical applications in preterm newborns. Neuroimage. 2016 Sep; 138:28-42. PMID: 27184202; PMCID: PMC4982765 [Available on 09/01/17].
    37. Pekmezci M, Nelson J, Su H, Hess C, Lawton MT, Sonmez M, Young WL, Kim H, Tihan T. Morphometric characterization of brain arteriovenous malformations for clinical and radiological studies to identify silent intralesional microhemorrhages. Clin Neuropathol. 2016 May-Jun; 35(3):114-21. PMID: 27049066; PMCID: PMC4910647.
    38. Oza VS, Feigenbaum DF, Jacquot C, Hess C, Siegel D, Frieden IJ. Fetal Alcohol Exposure and PHACE Syndrome: A Case and Autopsy Report. Pediatr Dermatol. 2016 May; 33(3):e179-e183. PMID: 27040890.
      View in: PubMed
    39. Zhu C, Haraldsson H, Tian B, Meisel K, Ko N, Lawton M, Grinstead J, Ahn S, Laub G, Hess C, Saloner D. High resolution imaging of the intracranial vessel wall at 3 and 7 T using 3D fast spin echo MRI. MAGMA. 2016 Jun; 29(3):559-70. PMID: 26946509.
      View in: PubMed
    40. Oza VS, Mamlouk MD, Hess C, Mathes EF, Frieden IJ. Role of Sirolimus in Advanced Kaposiform Hemangioendothelioma. Pediatr Dermatol. 2016 Mar-Apr; 33(2):e88-92. PMID: 26864138.
      View in: PubMed
    41. Talbott JF, Nout-Lomas YS, Wendland MF, Mukherjee P, Huie JR, Hess C, Mabray MC, Bresnahan JC, Beattie MS. Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma. 2016 05 15; 33(10):929-42. PMID: 26483094; PMCID: PMC4876499 [Available on 05/15/17].
    42. Frey KA, Lodge MA, Meltzer CC, Peller PJ, Wong TZ, Hess C, Petrella JR, Sair HI, Subramaniam RM. ACR-ASNR Practice Parameter for Brain PET/CT Imaging Dementia. Clin Nucl Med. 2016 Feb; 41(2):118-25. PMID: 26646994.
      View in: PubMed
    43. Schmied L, Terszowski G, Gonzalez A, Schmitter K, Hirsch HH, Garzoni C, van Delden C, Boggian K, Mueller NJ, Berger C, Villard J, Manuel O, Meylan P, Hess C, Stern M. Protection From Varicella Zoster in Solid Organ Transplant Recipients Carrying Killer Cell Immunoglobulin-Like Receptor B Haplotypes. Transplantation. 2015 Dec; 99(12):2651-5. PMID: 26050016.
      View in: PubMed
    44. Kim H, Gano D, Ho ML, Guo XM, Unzueta A, Hess C, Ferriero DM, Xu D, Barkovich AJ. Hindbrain regional growth in preterm newborns and its impairment in relation to brain injury. Hum Brain Mapp. 2016 Feb; 37(2):678-88. PMID: 26589992.
      View in: PubMed
    45. Antonov NK, Spence-Shishido A, Marathe KS, Tlougan B, Kazim M, Sultan S, Hess C, Morel KD, Frieden IJ, Garzon MC. Orbital Hemangioma with Intracranial Vascular Anomalies and Hemangiomas: A New Presentation of PHACE Syndrome? Pediatr Dermatol. 2015 Nov-Dec; 32(6):e267-72. PMID: 26446288.
      View in: PubMed
    46. Wen Q, Kelley DA, Banerjee S, Lupo JM, Chang SM, Xu D, Hess C, Nelson SJ. Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T. Neuroimage Clin. 2015; 9:291-9. PMID: 26509116; PMCID: PMC4579286.
    47. Gardner RC, Possin KL, Hess C, Huang EJ, Grinberg LT, Nolan AL, Cohn-Sheehy BI, Ghosh PM, Lanata S, Merrilees J, Kramer JH, Berger MS, Miller BL, Yaffe K, Rabinovici GD. Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series. Neurol Clin Pract. 2015 Aug; 5(4):285-295. PMID: 26336629.
      View in: PubMed
    48. Gardner RC, Hess C, Brus-Ramer M, Possin KL, Cohn-Sheehy BI, Kramer JH, Berger MS, Yaffe K, Miller B, Rabinovici GD. Cavum Septum Pellucidum in Retired American Pro-Football Players. J Neurotrauma. 2016 Jan 01; 33(1):157-61. PMID: 25970145; PMCID: PMC4696427 [Available on 01/01/17].
    49. Koo KS, Dowd CF, Mathes EF, Rosbe KW, Hoffman WY, Frieden IJ, Hess C. MRI phenotypes of localized intravascular coagulopathy in venous malformations. Pediatr Radiol. 2015 Oct; 45(11):1690-5. PMID: 26143286.
      View in: PubMed
    50. Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess C, Berger MS, Chang EF. Transient aphasias after left hemisphere resective surgery. J Neurosurg. 2015 Sep; 123(3):581-93. PMID: 26115463; PMCID: PMC4558229.
    51. Abla AA, Nelson J, Kim H, Hess C, Tihan T, Lawton MT. Silent arteriovenous malformation hemorrhage and the recognition of "unruptured" arteriovenous malformation patients who benefit from surgical intervention. Neurosurgery. 2015 May; 76(5):592-600; discussion 600. PMID: 25714514; PMCID: PMC4425306.
    52. Patel AS, Schulman JM, Ruben BS, Hoffman WY, Dowd CF, Frieden IJ, Hess C. Atypical MRI features in soft-tissue arteriovenous malformation: a novel imaging appearance with radiologic-pathologic correlation. Pediatr Radiol. 2015 Sep; 45(10):1515-21. PMID: 25916383; PMCID: PMC4553129.
    53. Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess C, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 09; 131(23):2061-2069. PMID: 25862742.
      View in: PubMed
    54. Mamlouk MD, Saket RR, Hess C, Dillon WP. Adding value in radiology: establishing a designated quality control radiologist in daily workflow. J Am Coll Radiol. 2015 Aug; 12(8):838-41. PMID: 25783992.
      View in: PubMed
    55. Chen Y, Tymofiyeva O, Hess C, Xu D. Effects of rejecting diffusion directions on tensor-derived parameters. Neuroimage. 2015 Apr 01; 109:160-70. PMID: 25585018; PMCID: PMC4339467.
    56. Bian W, Banerjee S, Kelly DA, Hess C, Larson PE, Chang SM, Nelson SJ, Lupo JM. Simultaneous imaging of radiation-induced cerebral microbleeds, arteries and veins, using a multiple gradient echo sequence at 7 Tesla. J Magn Reson Imaging. 2015 Aug; 42(2):269-79. PMID: 25471321; PMCID: PMC4876721.
    57. Osorio JA, Benet A, Hess C, McDermott MW, Abla AA. Primary vertebral artery reanastomosis during retrosigmoid skull base approach following iatrogenic near-transection with monopolar electrocautery. Neurosurgery. 2014 Dec; 10 Suppl 4:631-9. PMID: 25181436.
      View in: PubMed
    58. Alexandrescu S, Orengo JP, Toossi S, Perry A, Treseler P, Hess C, Margeta M. CNS intravascular large cell lymphoma in a patient with autoimmune hemolytic anemia. Neuropathology. 2015 Apr; 35(2):170-4. PMID: 25378202.
      View in: PubMed
    59. Caverzasi E, Mandelli ML, DeArmond SJ, Hess C, Vitali P, Papinutto N, Oehler A, Miller BL, Lobach IV, Bastianello S, Geschwind MD, Henry RG. White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54. PMID: 25367029; PMCID: PMC4240303.
    60. Gastelum E, Sear K, Hills N, Roddy E, Randazzo D, Chettout N, Hess C, Cotter J, Haas-Kogan DA, Fullerton H, Mueller S. Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients. J Child Neurol. 2015 Jun; 30(7):842-849. PMID: 25122111; PMCID: PMC4326593.
    61. Nguyen JT, Koerper MA, Hess C, Dowd CF, Hoffman WY, Dickman M, Frieden IJ. Aspirin therapy in venous malformation: a retrospective cohort study of benefits, side effects, and patient experiences. Pediatr Dermatol. 2014 Sep-Oct; 31(5):556-60. PMID: 25040175.
      View in: PubMed
    62. Tymofiyeva O, Ziv E, Barkovich AJ, Hess C, Xu D. Brain without anatomy: construction and comparison of fully network-driven structural MRI connectomes. PLoS One. 2014; 9(5):e96196. PMID: 24789312; PMCID: PMC4006896.
    63. Trattner S, Pearson GDN, Chin C, Cody DD, Gupta R, Hess C, Kalra MK, Kofler JM, Krishnam MS, Einstein AJ. Standardization and optimization of CT protocols to achieve low dose. J Am Coll Radiol. 2014 Mar; 11(3):271-278. PMID: 24589403; PMCID: PMC3969855.
    64. Graves J, Kraus V, Soares BP, Hess C, Waubant E. Longitudinally extensive optic neuritis in pediatric patients. J Child Neurol. 2015 Jan; 30(1):120-3. PMID: 24563470.
      View in: PubMed
    65. Desikan RS, Thompson WK, Holland D, Hess C, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. The role of clusterin in amyloid-ß-associated neurodegeneration. JAMA Neurol. 2014 Feb; 71(2):180-7. PMID: 24378367; PMCID: PMC4118752.
    66. Guo Y, Tihan T, Kim H, Hess C, Lawton MT, Young WL, Zhao Y, Su H. Distinctive distribution of lymphocytes in unruptured and previously untreated brain arteriovenous malformation. Neuroimmunol Neuroinflamm. 2014; 1(3):147-152. PMID: 25568888.
      View in: PubMed
    67. You SC, Geschwind MD, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess C, Kramer JH, Possin KL. Executive functions in premanifest Huntington's disease. Mov Disord. 2014 Mar; 29(3):405-9. PMID: 24375511; PMCID: PMC4029327.
    68. Hess C, Christine CW, Apple AC, Dillon WP, Aminoff MJ. Changes in the thalamus in atypical parkinsonism detected using shape analysis and diffusion tensor imaging. AJNR Am J Neuroradiol. 2014 May; 35(5):897-903. PMID: 24356677.
      View in: PubMed
    69. Bian W, Hess C, Chang SM, Nelson SJ, Lupo JM. Susceptibility-weighted MR imaging of radiation therapy-induced cerebral microbleeds in patients with glioma: a comparison between 3T and 7T. Neuroradiology. 2014 Feb; 56(2):91-6. PMID: 24281386; PMCID: PMC4940363.
    70. Ziv E, Tymofiyeva O, Ferriero DM, Barkovich AJ, Hess C, Xu D. A machine learning approach to automated structural network analysis: application to neonatal encephalopathy. PLoS One. 2013; 8(11):e78824. PMID: 24282501; PMCID: PMC3840059.
    71. Desikan RS, Thompson WK, Holland D, Hess C, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. Heart fatty acid binding protein and Aß-associated Alzheimer's neurodegeneration. Mol Neurodegener. 2013 Oct 02; 8:39. PMID: 24088526; PMCID: PMC3850652.
    72. Wu YW, Hess C, Singhal NS, Groden C, Toro C. Idiopathic basal ganglia calcifications: an atypical presentation of PKAN. Pediatr Neurol. 2013 Nov; 49(5):351-4. PMID: 23968566.
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    73. Vogel SA, Hess C, Dowd CF, Hoffman WY, Kane AJ, Rajaii R, Frieden IJ. Early versus later presentations of venous malformations: where and why? Pediatr Dermatol. 2013 Sep-Oct; 30(5):534-40. PMID: 23679583.
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    74. Tymofiyeva O, Hess C, Ziv E, Lee PN, Glass HC, Ferriero DM, Barkovich AJ, Xu D. A DTI-based template-free cortical connectome study of brain maturation. PLoS One. 2013; 8(5):e63310. PMID: 23675475; PMCID: PMC3652871.
    75. Bian W, Hess C, Chang SM, Nelson SJ, Lupo JM. Computer-aided detection of radiation-induced cerebral microbleeds on susceptibility-weighted MR images. Neuroimage Clin. 2013; 2:282-90. PMID: 24179783; PMCID: PMC3777794.
    76. Karampinos DC, Melkus G, Shepherd TM, Banerjee S, Saritas EU, Shankaranarayanan A, Hess C, Link TM, Dillon WP, Majumdar S. Diffusion tensor imaging and T2 relaxometry of bilateral lumbar nerve roots: feasibility of in-plane imaging. NMR Biomed. 2013 Jun; 26(6):630-7. PMID: 23208676; PMCID: PMC3634898.
    77. Hegde M, Santos-Sanchez C, Hess C, Kabir AA, Garcia PA. Seizure exacerbation in two patients with focal epilepsy following marijuana cessation. Epilepsy Behav. 2012 Dec; 25(4):563-6. PMID: 23159379.
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    78. Metry D, Frieden IJ, Hess C, Siegel D, Maheshwari M, Baselga E, Chamlin S, Garzon M, Mancini AJ, Powell J, Drolet BA. Propranolol use in PHACE syndrome with cervical and intracranial arterial anomalies: collective experience in 32 infants. Pediatr Dermatol. 2013 Jan-Feb; 30(1):71-89. PMID: 22994362; PMCID: PMC4995066.
    79. West TW, Hess C, Cree BA. Acute transverse myelitis: demyelinating, inflammatory, and infectious myelopathies. Semin Neurol. 2012 Apr; 32(2):97-113. PMID: 22961185.
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    80. Hess C, Dillon WP. Imaging the pituitary and parasellar region. Neurosurg Clin N Am. 2012 Oct; 23(4):529-42. PMID: 23040741.
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    81. Tangtiphaiboontana J, Hess C, Bayer M, Drolet BA, Nassif LM, Metry DW, Barkovich AJ, Frieden IJ, Fullerton HJ. Neurodevelopmental abnormalities in children with PHACE syndrome. J Child Neurol. 2013 May; 28(5):608-14. PMID: 22805249.
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    82. Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H, Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL. Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation. Transl Stroke Res. 2012 Jul; 3(Suppl 1):166-73. PMID: 23002401; PMCID: PMC3445332.
    83. Siegel DH, Tefft KA, Kelly T, Johnson C, Metry D, Burrows P, Pope E, Cordisco M, Holland KE, Maheshwari M, Keith P, Garzon M, Hess C, Frieden IJ, Fullerton HJ, Drolet BA. Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: a systematic review of the literature. Stroke. 2012 Jun; 43(6):1672-4. PMID: 22442177.
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    84. Tymofiyeva O, Hess C, Ziv E, Tian N, Bonifacio SL, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. Towards the "baby connectome": mapping the structural connectivity of the newborn brain. PLoS One. 2012; 7(2):e31029. PMID: 22347423; PMCID: PMC3274551.
    85. Guo Y, Saunders T, Su H, Kim H, Akkoc D, Saloner DA, Hetts SW, Hess C, Lawton MT, Bollen AW, Pourmohamad T, McCulloch CE, Tihan T, Young WL. Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture. Stroke. 2012 May; 43(5):1240-6. PMID: 22308253; PMCID: PMC3335931.
    86. Holbro A, Jauch A, Lardinois D, Tzankov A, Dirnhofer S, Hess C. High prevalence of infections and autoimmunity in patients with thymoma. Hum Immunol. 2012 Mar; 73(3):287-90. PMID: 22261388.
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    87. Lupo JM, Li Y, Hess C, Nelson SJ. Advances in ultra-high field MRI for the clinical management of patients with brain tumors. Curr Opin Neurol. 2011 Dec; 24(6):605-15. PMID: 22045220.
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    88. Lupo JM, Chuang CF, Chang SM, Barani IJ, Jimenez B, Hess C, Nelson SJ. 7-Tesla susceptibility-weighted imaging to assess the effects of radiotherapy on normal-appearing brain in patients with glioma. Int J Radiat Oncol Biol Phys. 2012 Mar 01; 82(3):e493-500. PMID: 22000750; PMCID: PMC3268881.
    89. Nabatian AS, Milgraum SS, Hess C, Mancini AJ, Krol A, Frieden IJ. PHACE without face? Infantile hemangiomas of the upper body region with minimal or absent facial hemangiomas and associated structural malformations. Pediatr Dermatol. 2011 May-Jun; 28(3):235-41. PMID: 21453307.
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    90. Brandon K, Burrows P, Hess C, Metry D. Arteriovenous malformation: a rare manifestation of PHACE syndrome. Pediatr Dermatol. 2011 Mar-Apr; 28(2):180-4. PMID: 21504447.
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    91. Hess C, Mukherjee P, Barbaro NM. Epileptic foci. J Neurosurg. 2011 Jun; 114(6):1691-2; discussion 1692. PMID: 21351830.
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    92. Hess C, Barkovich AJ. Seizures: emergency neuroimaging. Neuroimaging Clin N Am. 2010 Nov; 20(4):619-37. PMID: 20974379.
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    93. Rosbe KW, Hess C, Dowd CF, Frieden IJ. Masseteric venous malformations: diagnosis, treatment, and outcomes. Otolaryngol Head Neck Surg. 2010 Dec; 143(6):779-83. PMID: 21109077.
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    94. Desikan RS, Sabuncu MR, Schmansky NJ, Reuter M, Cabral HJ, Hess C, Weiner MW, Biffi A, Anderson CD, Rosand J, Salat DH, Kemper TL, Dale AM, Sperling RA, Fischl B. Selective disruption of the cerebral neocortex in Alzheimer's disease. PLoS One. 2010 Sep 23; 5(9):e12853. PMID: 20886094.
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    95. von Morze C, Kelley DA, Shepherd TM, Banerjee S, Xu D, Hess C. Reduced field-of-view diffusion-weighted imaging of the brain at 7 T. Magn Reson Imaging. 2010 Dec; 28(10):1541-5. PMID: 20850242; PMCID: PMC2988970.
    96. Koontz NA, Hess C. AJR teaching file: brain tumor in a patient with familial adenomatous polyposis. AJR Am J Roentgenol. 2010 Sep; 195(3 Suppl):S25-8. PMID: 20729408.
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    97. Burnett MM, Hess C, Roberts JP, Bass NM, Douglas VC, Josephson SA. Presentation of reversible posterior leukoencephalopathy syndrome in patients on calcineurin inhibitors. Clin Neurol Neurosurg. 2010 Dec; 112(10):886-91. PMID: 20800343.
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    98. Hess C, Fullerton HJ, Metry DW, Drolet BA, Siegel DH, Auguste KI, Gupta N, Haggstrom AN, Dowd CF, Frieden IJ, Barkovich AJ. Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR Am J Neuroradiol. 2010 Nov; 31(10):1980-6. PMID: 20705698.
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    99. Raj A, Hess C, Mukherjee P. Spatial HARDI: improved visualization of complex white matter architecture with Bayesian spatial regularization. Neuroimage. 2011 Jan 01; 54(1):396-409. PMID: 20670684; PMCID: PMC2962674.
    100. Desikan RS, Cabral HJ, Settecase F, Hess C, Dillon WP, Glastonbury CM, Weiner MW, Schmansky NJ, Salat DH, Fischl B. Automated MRI measures predict progression to Alzheimer's disease. Neurobiol Aging. 2010 Aug; 31(8):1364-74. PMID: 20570399; PMCID: PMC2902697.
    101. Toossi S, Hess C, Hills NK, Josephson SA. Neurovascular complications of cocaine use at a tertiary stroke center. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):273-8. PMID: 20444626.
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    102. Stern M, Opelz G, Döhler B, Hess C. Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma. Blood. 2010 May 13; 115(19):3960-5. PMID: 20207982.
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    103. Metry D, Heyer G, Hess C, Garzon M, Haggstrom A, Frommelt P, Adams D, Siegel D, Hall K, Powell J, Frieden I, Drolet B. Consensus Statement on Diagnostic Criteria for PHACE Syndrome. Pediatrics. 2009 Nov; 124(5):1447-56. PMID: 19858157.
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    104. Cantoni N, Meyer P, Katan M, Kappos L, Hess C, Daikeler T. A confusing patient's history: small or large vessel vasculitis? Rheumatol Int. 2010 Nov; 30(12):1681-3. PMID: 19774381.
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    105. Metry DW, Garzon MC, Drolet BA, Frommelt P, Haggstrom A, Hall J, Hess C, Heyer GL, Siegel D, Baselga E, Katowitz W, Levy ML, Mancini A, Maronn ML, Phung T, Pope E, Sun G, Frieden IJ. PHACE syndrome: current knowledge, future directions. Pediatr Dermatol. 2009 Jul-Aug; 26(4):381-98. PMID: 19689512.
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    106. Desikan RS, Cabral HJ, Hess C, Dillon WP, Glastonbury CM, Weiner MW, Schmansky NJ, Greve DN, Salat DH, Buckner RL, Fischl B. Automated MRI measures identify individuals with mild cognitive impairment and Alzheimer's disease. Brain. 2009 Aug; 132(Pt 8):2048-57. PMID: 19460794; PMCID: PMC2714061.
    107. Hess C. Update on diffusion tensor imaging in Alzheimer's disease. Magn Reson Imaging Clin N Am. 2009 May; 17(2):215-24. PMID: 19406355.
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    108. Hess C, Mukherjee P. Visualizing white matter pathways in the living human brain: diffusion tensor imaging and beyond. Neuroimaging Clin N Am. 2007 Nov; 17(4):407-26, vii. PMID: 17983960.
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    109. Purcell DD, Hess C, Durack JC, Breiman RS. Recording, editing, archiving, and distributing radiology lectures: a streamlined approach. Radiographics. 2007 Nov-Dec; 27(6):1839-44. PMID: 18025522.
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    110. von Morze C, Xu D, Purcell DD, Hess C, Mukherjee P, Saloner D, Kelley DA, Vigneron DB. Intracranial time-of-flight MR angiography at 7T with comparison to 3T. J Magn Reson Imaging. 2007 Oct; 26(4):900-4. PMID: 17896360.
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    111. Berman JI, Chung S, Mukherjee P, Hess C, Han ET, Henry RG. Probabilistic streamline q-ball tractography using the residual bootstrap. Neuroimage. 2008 Jan 01; 39(1):215-22. PMID: 17911030.
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    112. Mukherjee P, Hess C, Xu D, Han ET, Kelley DA, Vigneron DB. Development and initial evaluation of 7-T q-ball imaging of the human brain. Magn Reson Imaging. 2008 Feb; 26(2):171-80. PMID: 17692489; PMCID: PMC2997615.
    113. Gasser O, Bihl FK, Wolbers M, Loggi E, Steffen I, Hirsch HH, Günthard HF, Walker BD, Brander C, Battegay M, Hess C. HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts. PLoS Med. 2007 Mar 27; 4(3):e96. PMID: 17388662; PMCID: PMC1831733.
    114. Hess C, Mukherjee P, Han ET, Xu D, Vigneron DB. Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis. Magn Reson Med. 2006 Jul; 56(1):104-17. PMID: 16755539.
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