Daniel Bikle, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #210
San Francisco CA 94143
Phone415-750-2089
ORCID ORCID Icon0000-0002-1040-475x Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    HarvardAB1965Harvard
    University of PennsylvaniaMD1969School of Medicine
    University of PennsylvaniaPhD1974Graduate School of Arts and Sciences
    Collapse Awards and Honors
    Harvard1965Henderson Memorial Prize in Biochemistry
    Harvard1965Magna Cum Laude
    University of Pennsylvania1966Baldwin Lucke Memorial Prize
    University of Pennsylvania1968alpha omega alpha
    University of Pennsylvania1969Horatio C Wood Prize in Pharmacology
    University of Pennsylvania1969Borden Research Award
    University of Pennsylvania1969Spencer Morris Prize
    American College of Physicians1982Fellow, American College of Physicians
    American Society of Clinical Investigation1985member American Society of Clinical Investigation
    Association of American Physicians1995member Association of American Physicians
    ASBMR2007Boy Frame Award for Clinical Excellence in Bone and Mineral Research
    International Workshop for Vitamin D2009Career Award in Vitamin D research
    ASBMR2016Louis V Avioli Founders Award
    ASBMR2019Fellowship, ASBMR

    Collapse Overview 
    Collapse Overview
    I am Professor of Medicine and Dermatology emeritus on call back at UCSF and staff Endocrinologist at SFVAMC. I continue both my clinical activities and direct a well funded laboratory investigating hormonal regulation of fracture healing and vitamin D and calcium regulation of both skin cancer and wound response.

    Collapse Research 
    Collapse Research Activities and Funding
    BCCMA: Foundational Research to Act Upon and Resist Conditions Unfavorable to bone (FRACTURECURB): Role of abaloparatide for fracture healing
    VA 1I01 BX005854Oct 1, 2022 - Sep 30, 2026
    Role: PI
    Description: This project will examine the molecular and cellular mechanisms by which abaloparatide enhances fracture repair
    Biomechanical computed tomography facilitates the diagnosis of osteoporosis and fracture prediction in patients with high risk prostate cancer
    DOD PC210172Jun 1, 2022 - May 31, 2026
    Role: PI
    Description: This project will use biomechanical computed tomography to determine the risk of osteoporosis and fracture in individuals being reated with high risk prostate cancer
    Maladaptive Plasticity in Spinal Cord Injury: Cellular Mechanisms
    NIH R01NS122888Jul 15, 2021 - Jun 3, 2026
    Role: PI of subcontract
    Description: To explore the spinal cellular mechanisms engaged by concomitant peripheral injuries and limb disuse in SCI, and to test their contribution to spasticity/hyper-reflexia and chronic spinal recovery impairments
    Vitamin D and Calcium signaling in epidermal stem cell maintenance, activation, and function
    NIH I01BX003814Jan 1, 2018 - Dec 31, 2021
    Role: Principal Investigator
    Role of IGF-I/integrin signaling in the periosteal response to load
    NIH R01AR055924Apr 1, 2008 - Jan 31, 2021
    Role: Principal Investigator
    Vitamin D Receptor Coactivators in Keratinocytes
    NIH R01AR050023Jul 1, 2003 - May 31, 2016
    Role: Principal Investigator
    IGF-1 Mediates the Anabolic Effects of PTH on Bone
    NIH R01DK054793Feb 15, 2001 - Aug 31, 2015
    Role: Principal Investigator
    ESTROGEN/CALCITRIOL IN THE ETIOLOGY OF BREAST CANCER
    NIH R03CA070572Sep 30, 1995 - Mar 31, 1999
    Role: Principal Investigator
    Relationship of Keratinocyte Function to Differentiation
    NIH P01AR039448Jul 15, 1988 - Jul 31, 2010
    Role: Principal Investigator
    VITAMIN D AND THE DIFFERENTIATION OF KERATINOCYTES
    NIH R01AR038386May 1, 1987 - Mar 31, 2005
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    REGULATION OF INTESTINAL CALCIUM TRANSPORT BY VITAMIN D
    NIH R01DK028116Apr 1, 1981 - Jun 30, 2004
    Role: Principal Investigator
    VITAMIN D STIMULATED INTESTINAL CALCIUM TRANSPORT
    NIH R01AM028116Apr 1, 1981 - Mar 31, 1987
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows. Endocr Rev. 2024 Sep 12; 45(5):625-654. Giustina A, Bilezikian JP, Adler RA, Banfi G, Bikle DD, Binkley NC, Bollerslev J, Bouillon R, Brandi ML, Casanueva FF, di Filippo L, Donini LM, Ebeling PR, Fuleihan GE, Fassio A, Frara S, Jones G, Marcocci C, Martineau AR, Minisola S, Napoli N, Procopio M, Rizzoli R, Schafer AL, Sempos CT, Ulivieri FM, Virtanen JK. PMID: 38676447; PMCID: PMC11405507.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    2. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2024 Jul 12; 109(8):1907-1947. Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh JME, McCartney CR. PMID: 38828931.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    3. Vitamin D and Long COVID: Is There a Role in Prevention or Treatment? J Clin Endocrinol Metab. 2023 Dec 21; 109(1):e430-e431. Bikle DD. PMID: 37279939.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Validation of Biomechanical Computed Tomography for Fracture Risk Classification in Metastatic Hormone-sensitive Prostate Cancer. Eur Urol Oncol. 2024 Aug; 7(4):794-803. Lin JK, Hearn CM, Getzen E, Long Q, Lee DC, Keaveny TM, Jayadevappa R, Robinson KW, Wong YN, Maxwell KN, Narayan V, Haas NB, Takvorian SU, Bikle DD, Chiang JM, Khan AN, Rajapakse CS, Morgans AK, Parikh RB. PMID: 37926618; PMCID: PMC11268319.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics. Commun Biol. 2023 07 21; 6(1):766. Thaler R, Yoshizaki K, Nguyen T, Fukumoto S, Den Besten P, Bikle DD, Oda Y. PMID: 37479880; PMCID: PMC10362024.
      View in: PubMed   Mentions: 2  Translation:AnimalsCells
    6. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate. J Steroid Biochem Mol Biol. 2023 09; 232:106352. Oda Y, Wong CT, Oh DH, Meyer MB, Pike JW, Bikle DD. PMID: 37330071.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship? Rev Endocr Metab Disord. 2023 04; 24(2):121-138. Giustina A, di Filippo L, Allora A, Bikle DD, Cavestro GM, Feldman D, Latella G, Minisola S, Napoli N, Trasciatti S, Uygur M, Bilezikian JP. PMID: 36813995; PMCID: PMC9946876.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    8. Highlights from the 24th workshop on vitamin D in Austin, September 2022. J Steroid Biochem Mol Biol. 2023 04; 228:106247. Meyer MB, Bernal-Mizrachi C, Bikle DD, Biyani M, Campbell MJ, Chaudhari SN, Christakos S, Ingles SA, Knuth MM, Lee SM, Lisse TS, Liu ES, Piec I, Plum LA, Rao SD, Reynolds CJ, Thacher TD, White JH, Cantorna MT. PMID: 36639037; PMCID: PMC10006320.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Prevalence of osteoporosis in older male veterans receiving hip-containing computed tomography scans: opportunistic use of biomechanical computed tomography analysis (BCT). Osteoporos Int. 2023 Mar; 34(3):551-561. Teng PF, Chiang JM, Schafer AL, Sukerkar PA, Keaveny TM, Bikle D. PMID: 36580097; PMCID: PMC9908633.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Skin and bone crosstalk during aging. Nat Aging. 2022 10; 2(10):874-875. Mauro T, Bikle D. PMID: 37118286.
      View in: PubMed   Mentions:    Fields:    
    11. Role of vitamin D and calcium signaling in epidermal wound healing. J Endocrinol Invest. 2023 Feb; 46(2):205-212. Bikle DD. PMID: 35963983; PMCID: PMC9859773.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    12. Response to Letters to the Editor RE: Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality. J Gen Intern Med. 2022 10; 37(13):3494. Seal KH, Bertenthal D, Bikle DD. PMID: 35727478; PMCID: PMC9209827.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Vitamin D Regulation of Immune Function. Curr Osteoporos Rep. 2022 06; 20(3):186-193. Bikle DD. PMID: 35507293; PMCID: PMC9065668.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    14. Vitamin D regulation of immune function during covid-19. Rev Endocr Metab Disord. 2022 04; 23(2):279-285. Bikle DD. PMID: 35091881; PMCID: PMC8799423.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    15. Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality. J Gen Intern Med. 2022 03; 37(4):853-861. Seal KH, Bertenthal D, Carey E, Grunfeld C, Bikle DD, Lu CM. PMID: 34981368; PMCID: PMC8723909.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    16. Ligand-Independent Actions of the Vitamin D Receptor: More Questions Than Answers. JBMR Plus. 2021 Dec; 5(12):e10578. Bikle DD. PMID: 34950833; PMCID: PMC8674770.
      View in: PubMed   Mentions: 6  
    17. Hypercalcemia in non-Hodgkin's lymphoma due to cosecretion of PTHrP and 1,25-dihydroxyvitamin D. Osteoporos Int. 2021 Dec; 32(12):2587-2592. Gonciulea AR, Wang Y, Bikle DD, Sellmeyer DE. PMID: 34230999.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Vitamin D regulation of and by long non coding RNAs. Mol Cell Endocrinol. 2021 07 15; 532:111317. Bikle DD. PMID: 34015414.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    19. Decreased Calcium-Sensing Receptor Expression Controls Calcium Signaling and Cell-To-Cell Adhesion Defects in Aged Skin. J Invest Dermatol. 2021 11; 141(11):2577-2586. Celli A, Tu CL, Lee E, Bikle DD, Mauro TM. PMID: 33862069; PMCID: PMC8526647.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    20. Introduction: Special Issue on Vitamin D Dedicated to the Memory of Anthony W Norman. JBMR Plus. 2021 Jan; 5(1):e10445. Bouillon R, Haussler M, Bikle D, Christakos S, Welsh J. PMID: 33553991; PMCID: PMC7839816.
      View in: PubMed   Mentions: 1  
    21. Ablation of Ephrin B2 in Col2 Expressing Cells Delays Fracture Repair. Endocrinology. 2020 12 01; 161(12). Wang Y, Ling L, Tian F, Won Kim SH, Ho S, Bikle DD. PMID: 32987403; PMCID: PMC7609132.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    22. Transcriptional Regulation of Dental Epithelial Cell Fate. Int J Mol Sci. 2020 Nov 25; 21(23). Yoshizaki K, Fukumoto S, Bikle DD, Oda Y. PMID: 33255698; PMCID: PMC7728066.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    23. The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status. JBMR Plus. 2021 Jan; 5(1):e10418. Bikle DD. PMID: 33553985; PMCID: PMC7839820.
      View in: PubMed   Mentions: 35  
    24. MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19. Eur J Endocrinol. 2020 Nov; 183(5):R133-R147. Bilezikian JP, Bikle D, Hewison M, Lazaretti-Castro M, Formenti AM, Gupta A, Madhavan MV, Nair N, Babalyan V, Hutchings N, Napoli N, Accili D, Binkley N, Landry DW, Giustina A. PMID: 32755992; PMCID: PMC9494342.
      View in: PubMed   Mentions: 189     Fields:    Translation:HumansCellsPHPublic Health
    25. Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration. PLoS One. 2020; 15(8):e0238076. Oda Y, Nguyen T, Hata A, Meyer MB, Pike JW, Bikle DD. PMID: 32857768; PMCID: PMC7455038.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    26. Vitamin D and calcium signaling in epidermal stem cells and their regeneration. World J Stem Cells. 2020 Jul 26; 12(7):604-611. Oda Y, Bikle DD. PMID: 32843916; PMCID: PMC7415249.
      View in: PubMed   Mentions: 6  
    27. p120-catenin suppresses proliferation and tumor growth of oral squamous cell carcinoma via inhibiting nuclear phospholipase C-γ1 signaling. J Cell Physiol. 2020 12; 235(12):9399-9413. Li L, Ji S, Shrestha C, Jiang Y, Liao L, Xu F, Liu Z, Bikle DD, Xie Z. PMID: 32356317; PMCID: PMC7529923.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    28. Editorial: Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions. Front Endocrinol (Lausanne). 2020; 11:40. Xie Z, Wang X, Bikle DD. PMID: 32117066; PMCID: PMC7026452.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. New aspects of vitamin D metabolism and action - addressing the skin as source and target. Nat Rev Endocrinol. 2020 04; 16(4):234-252. Bikle D, Christakos S. PMID: 32029884.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    30. Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level. J Endocr Soc. 2020 Feb 01; 4(2):bvz038. Bikle DD. PMID: 32051922; PMCID: PMC7007804.
      View in: PubMed   Mentions: 60  
    31. The Vitamin D Receptor as Tumor Suppressor in Skin. Adv Exp Med Biol. 2020; 1268:285-306. Bikle DD. PMID: 32918224.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    32. Vitamin D Metabolism Revised: Fall of Dogmas. J Bone Miner Res. 2019 11; 34(11):1985-1992. Bouillon R, Bikle D. PMID: 31589774; PMCID: PMC9000993.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    33. Myosin 1a Regulates Osteoblast Differentiation Independent of Intestinal Calcium Transport. J Endocr Soc. 2019 Nov 01; 3(11):1993-2011. Munson S, Wang Y, Chang W, Bikle DD. PMID: 31620669; PMCID: PMC6789431.
      View in: PubMed   Mentions: 3  
    34. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Endocr Rev. 2019 08 01; 40(4):1109-1151. Bouillon R, Marcocci C, Carmeliet G, Bikle D, White JH, Dawson-Hughes B, Lips P, Munns CF, Lazaretti-Castro M, Giustina A, Bilezikian J. PMID: 30321335; PMCID: PMC6626501.
      View in: PubMed   Mentions: 420     Fields:    Translation:HumansAnimalsCells
    35. Do sunscreens block vitamin D production? A critical review by an international panel of experts. Br J Dermatol. 2019 11; 181(5):884. Bikle DD. PMID: 31259384; PMCID: PMC9002342.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. New developments in our understanding of vitamin metabolism, action and treatment. Metabolism. 2019 09; 98:112-120. Christakos S, Li S, De La Cruz J, Bikle DD. PMID: 31226354; PMCID: PMC6814307.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    37. Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions. Front Endocrinol (Lausanne). 2019; 10:317. Bikle DD, Schwartz J. PMID: 31191450; PMCID: PMC6546814.
      View in: PubMed   Mentions: 155     Fields:    
    38. The Fracture Callus Is Formed by Progenitors of Different Skeletal Origins in a Site-Specific Manner. JBMR Plus. 2019 Sep; 3(9):e10193. Wang Y, Chen L, Kang M, Ling L, Tian F, Won-Kim SH, Ho S, Bikle DD. PMID: 31667451; PMCID: PMC6808225.
      View in: PubMed   Mentions: 2  
    39. Rapid onset of hypercalcemia from high-grade lymphoma in the setting of HIV-related immune reconstitution inflammatory syndrome. Bone Rep. 2019 Jun; 10:100194. Kim SJ, Peluso MJ, Wang Y, Bikle D, Shoback D, Kim S. PMID: 30627599; PMCID: PMC6319307.
      View in: PubMed   Mentions: 2  
    40. Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations. J Clin Endocrinol Metab. 2018 09 01; 103(9):3278-3288. Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D. PMID: 29955795; PMCID: PMC6126881.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    41. Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D. Br J Clin Pharmacol. 2018 10; 84(10):2194-2207. Sempos CT, Heijboer AC, Bikle DD, Bollerslev J, Bouillon R, Brannon PM, DeLuca HF, Jones G, Munns CF, Bilezikian JP, Giustina A, Binkley N. PMID: 29851137; PMCID: PMC6138489.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    42. Vitamin D and bone and beyond. Bone Rep. 2018 Dec; 9:120-121. Bikle DD, Bouillon R. PMID: 30591929; PMCID: PMC6303270.
      View in: PubMed   Mentions: 3  
    43. p120-catenin is required for regulating epidermal proliferation, differentiation, and barrier function. J Cell Physiol. 2018 01; 234(1):427-432. Xie Z, Tang Y, Man MQ, Shrestha C, Bikle DD. PMID: 29923340; PMCID: PMC9000995.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    44. Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair. J Invest Dermatol. 2018 11; 138(11):2423-2431. Oda Y, Hu L, Nguyen T, Fong C, Zhang J, Guo P, Bikle DD. PMID: 29787748; PMCID: PMC6903414.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    45. Vitamin D Assays. Front Horm Res. 2018; 50:14-30. Bikle DD. PMID: 29597233; PMCID: PMC9000996.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    46. Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review. Bone Rep. 2018 Jun; 8:255-267. Bikle DD, Patzek S, Wang Y. PMID: 29963603; PMCID: PMC6021194.
      View in: PubMed   Mentions: 49  
    47. Current Controversies: Are Free Vitamin Metabolite Levels a More Accurate Assessment of Vitamin D Status than Total Levels? Endocrinol Metab Clin North Am. 2017 12; 46(4):901-918. Bikle DD, Malmstroem S, Schwartz J. PMID: 29080642; PMCID: PMC5675107.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    48. IGF-1 signaling mediated cell-specific skeletal mechano-transduction. J Orthop Res. 2018 02; 36(2):576-583. Tian F, Wang Y, Bikle DD. PMID: 28980721; PMCID: PMC5839951.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    49. Vitamin D Prevents Sunburn: Tips for the Summer? J Invest Dermatol. 2017 10; 137(10):2045-2047. Bikle DD. PMID: 28941472; PMCID: PMC9004584.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. Vitamin D: Mechanisms of Action and Clinical Applications. Endocrinol Metab Clin North Am. 2017 12; 46(4):xvii-xviii. Gallagher JC, Bikle DD. PMID: 29080648.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene. J Biol Chem. 2017 08 18; 292(33):13531-13540. Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y. PMID: 28673966; PMCID: PMC5566513.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    52. Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization. Endocrinology. 2017 06 01; 158(6):1929-1938. Oda Y, Hu L, Nguyen T, Fong C, Tu CL, Bikle DD. PMID: 28368538; PMCID: PMC5460927.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    53. Current Assays to Determine Free 25-Hydroxyvitamin D in Serum. J AOAC Int. 2017 Sep 01; 100(5):1323-1327. Malmstroem S, Rejnmark L, Imboden JB, Shoback DM, Bikle DD. PMID: 28492133.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    54. VITAMIN D BINDING PROTEIN AND 25-HYDROXYVITAMIN D LEVELS: EMERGING CLINICAL APPLICATIONS. Endocr Pract. 2017 May; 23(5):605-613. Jassil NK, Sharma A, Bikle D, Wang X. PMID: 28095044; PMCID: PMC9000994.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    55. Vitamin D metabolites in captivity? Should we measure free or total 25(OH)D to assess vitamin D status? J Steroid Biochem Mol Biol. 2017 10; 173:105-116. Bikle D, Bouillon R, Thadhani R, Schoenmakers I. PMID: 28093353; PMCID: PMC9005158.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    56. p120-Catenin Is Required for Dietary Calcium Suppression of Oral Carcinogenesis in Mice. J Cell Physiol. 2017 Jun; 232(6):1360-1367. Xie Z, Yuan Y, Jiang Y, Shrestha C, Chen Y, Liao L, Ji S, Deng X, Liao E, Bikle DD. PMID: 27682597; PMCID: PMC9000997.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    57. Osteogenic Differentiation of Periosteal Cells During Fracture Healing. J Cell Physiol. 2017 05; 232(5):913-921. Wang T, Zhang X, Bikle DD. PMID: 27731505; PMCID: PMC5247290.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    58. The vitamin D hypothesis: Dead or alive?: Response to Dr. William Grant's "The UVB-vitamin D3-pigment hypothesis is alive and well-AJPA-2016-00237". Am J Phys Anthropol. 2016 12; 161(4):756-757. Elias PM, Williams ML, Bikle DD. PMID: 27634223; PMCID: PMC9000992.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. Front Physiol. 2016; 7:296. Bikle DD, Jiang Y, Nguyen T, Oda Y, Tu CL. PMID: 27462278; PMCID: PMC4940389.
      View in: PubMed   Mentions: 34  
    60. Extraskeletal actions of vitamin D. Ann N Y Acad Sci. 2016 07; 1376(1):29-52. Bikle DD. PMID: 27649525; PMCID: PMC5031366.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimals
    61. Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation. Biomed Res Int. 2016; 2016:3062765. Shrestha C, Tang Y, Fan H, Li L, Zeng Q, Pennypacker SD, Bikle DD, Xie Z. PMID: 27340655; PMCID: PMC4909930.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    62. The Endocrine Society Centennial: Extrarenal Production of 1,25 Dihyroxyvitamin D Is Now Proven. Endocrinology. 2016 05; 157(5):1717-8. Bikle DD. PMID: 27014941; PMCID: PMC6415900.
      View in: PubMed   Mentions: 5     Fields:    
    63. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle. J Invest Dermatol. 2016 07; 136(7):1337-1345. Mady LJ, Ajibade DV, Hsaio C, Teichert A, Fong C, Wang Y, Christakos S, Bikle DD. PMID: 26994969; PMCID: PMC9020884.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    64. Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway. J Biol Chem. 2016 Apr 08; 291(15):8140-9. Tahimic CG, Long RK, Kubota T, Sun MY, Elalieh H, Fong C, Menendez AT, Wang Y, Vilardaga JP, Bikle DD. PMID: 26865633; PMCID: PMC4825016.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    65. Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites. Eur J Med Chem. 2016 Feb 15; 109:238-46. Teske KA, Bogart JW, Sanchez LM, Yu OB, Preston JV, Cook JM, Silvaggi NR, Bikle DD, Arnold LA. PMID: 26774929; PMCID: PMC4737989.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    66. Response of Vitamin D Concentration to Vitamin D3 Administration in Older Adults without Sun Exposure: A Randomized Double-Blind Trial. J Am Geriatr Soc. 2016 Jan; 64(1):65-72. Schwartz JB, Kane L, Bikle D. PMID: 26782853; PMCID: PMC4724876.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    67. Role of IGF-I signaling in muscle bone interactions. Bone. 2015 Nov; 80:79-88. Bikle DD, Tahimic C, Chang W, Wang Y, Philippou A, Barton ER. PMID: 26453498; PMCID: PMC4600536.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    68. Antitumor Activity of 3-Indolylmethanamines 31B and PS121912. Anticancer Res. 2015 Nov; 35(11):6001-7. Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA. PMID: 26504023; PMCID: PMC4633305.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    69. Pregnane X receptor expression in skin: the good and the bad. Exp Dermatol. 2015 Nov; 24(11):829-30. Bikle DD. PMID: 26269123; PMCID: PMC9000991.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    70. Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing. J Bone Miner Res. 2015 Sep; 30(9):1572-84. Wang T, Wang Y, Menendez A, Fong C, Babey M, Tahimic CG, Cheng Z, Li A, Chang W, Bikle DD. PMID: 25801198; PMCID: PMC5690481.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    71. Vitamin D and calcium regulation of epidermal wound healing. J Steroid Biochem Mol Biol. 2016 11; 164:379-385. Oda Y, Tu CL, Menendez A, Nguyen T, Bikle DD. PMID: 26282157; PMCID: PMC4753150.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    72. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Calcif Tissue Int. 2015 Dec; 97(6):634-9. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. PMID: 26253396; PMCID: PMC4861400.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    73. IGF-I Signaling in Osterix-Expressing Cells Regulates Secondary Ossification Center Formation, Growth Plate Maturation, and Metaphyseal Formation During Postnatal Bone Development. J Bone Miner Res. 2015 Dec; 30(12):2239-48. Wang Y, Menendez A, Fong C, ElAlieh HZ, Kubota T, Long R, Bikle DD. PMID: 26011431; PMCID: PMC9042009.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    74. Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. J Clin Endocrinol Metab. 2015 Aug; 100(8):2832-6. Shah AD, Hsiao EC, O'Donnell B, Salmeen K, Nussbaum R, Krebs M, Baumgartner-Parzer S, Kaufmann M, Jones G, Bikle DD, Wang Y, Mathew AS, Shoback D, Block-Kurbisch I. PMID: 26097993; PMCID: PMC4524985.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    75. Gender-Specific Differences in the Skeletal Response to Continuous PTH in Mice Lacking the IGF1 Receptor in Mature Osteoblasts. J Bone Miner Res. 2015 Jun; 30(6):1064-76. Babey M, Wang Y, Kubota T, Fong C, Menendez A, ElAlieh HZ, Bikle DD. PMID: 25502173; PMCID: PMC9045460.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    76. Selective Hyaluronan-CD44 Signaling Promotes miRNA-21 Expression and Interacts with Vitamin D Function during Cutaneous Squamous Cell Carcinomas Progression Following UV Irradiation. Front Immunol. 2015; 6:224. Bourguignon LY, Bikle D. PMID: 26029210; PMCID: PMC4429634.
      View in: PubMed   Mentions: 11     Fields:    
    77. UVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo. Exp Dermatol. 2015 May; 24(5):370-6. Tiganescu A, Hupe M, Jiang YJ, Celli A, Uchida Y, Mauro TM, Bikle DD, Elias PM, Holleran WM. PMID: 25739654; PMCID: PMC6365099.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    78. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. Liver Int. 2015 Oct; 35(10):2294-300. Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB. PMID: 25757956; PMCID: PMC4567539.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    79. Highlights from the 17th workshop on vitamin D, Chicago, IL, June 17-21, 2014. J Steroid Biochem Mol Biol. 2015 Apr; 148:1-2. Welsh J, Bikle DD, Lips P. PMID: 25641118; PMCID: PMC6756164.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    80. Vitamin D receptor, a tumor suppressor in skin. Can J Physiol Pharmacol. 2015 May; 93(5):349-54. Bikle DD. PMID: 25559384; PMCID: PMC9000998.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    81. Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer. J Steroid Biochem Mol Biol. 2015 Apr; 148:47-51. Bikle DD, Oda Y, Tu CL, Jiang Y. PMID: 25445917; PMCID: PMC4361259.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    82. Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production. Evol Biol. 2014 Sep 01; 41(3):388-396. Thyssen JP, Bikle DD, Elias PM. PMID: 25506102; PMCID: PMC4261051.
      View in: PubMed   Mentions: 17  
    83. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemother Pharmacol. 2014 Oct; 74(4):787-98. Sidhu PS, Teske K, Feleke B, Yuan NY, Guthrie ML, Fernstrum GB, Vyas ND, Han L, Preston J, Bogart JW, Silvaggi NR, Cook JM, Singh RK, Bikle DD, Arnold LA. PMID: 25107568; PMCID: PMC4177010.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    84. Ephrin B2/EphB4 mediates the actions of IGF-I signaling in regulating endochondral bone formation. J Bone Miner Res. 2014 Aug; 29(8):1900-13. Wang Y, Menendez A, Fong C, ElAlieh HZ, Chang W, Bikle DD. PMID: 24677183; PMCID: PMC4108521.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    85. Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair. PLoS One. 2014; 9(6):e99991. Yoshizaki K, Hu L, Nguyen T, Sakai K, He B, Fong C, Yamada Y, Bikle DD, Oda Y. PMID: 24949995; PMCID: PMC4065011.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    86. Calcium, Orai1, and epidermal proliferation. J Invest Dermatol. 2014 Jun; 134(6):1506-1508. Bikle DD, Mauro TM. PMID: 24825060; PMCID: PMC4023905.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    87. Highlights from the 16th Vitamin D Workshop, San Francisco, CA, June 11-14, 2013. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:1-4. Bikle D. PMID: 24793579.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    88. LncRNA: a new player in 1α, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation. Exp Dermatol. 2014 Mar; 23(3):147-50. Jiang YJ, Bikle DD. PMID: 24499465; PMCID: PMC4103949.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    89. Vitamin D-binding protein and vitamin D in blacks and whites. N Engl J Med. 2014 02 27; 370(9):879-80. Hollis BW, Bikle DD. PMID: 24571766; PMCID: PMC4165606.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    90. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Mar 20; 21(3):319-29. Bikle DD. PMID: 24529992; PMCID: PMC3968073.
      View in: PubMed   Mentions: 635     Fields:    Translation:HumansCells
    91. Development of novel Vitamin D Receptor-Coactivator Inhibitors. ACS Med Chem Lett. 2014 Feb 13; 5(2):199-204. Sidhu PS, Nassif N, McCallum MM, Teske K, Feleke B, Yuan NY, Nandhikonda P, Cook JM, Singh RK, Bikle DD, Arnold LA. PMID: 24799995; PMCID: PMC4007349.
      View in: PubMed   Mentions: 12  
    92. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab. 2014 May; 99(5):1631-7. Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D. PMID: 24483159; PMCID: PMC4010704.
      View in: PubMed   Mentions: 102     Fields:    Translation:Humans
    93. Vitamin D and cancer: the promise not yet fulfilled. Endocrine. 2014 May; 46(1):29-38. Bikle DD. PMID: 24402695; PMCID: PMC3976762.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    94. IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING. Nucl Receptor Res. 2014; 1. Teske K, Nandhikonda P, Bogart JW, Feleke B, Sidhu P, Yuan N, Preston J, Goy R, Han L, Silvaggi NR, Singh RK, Bikle DD, Cook JM, Arnold LA. PMID: 25419525; PMCID: PMC4240308.
      View in: PubMed   Mentions: 7  
    95. The vitamin D receptor: a tumor suppressor in skin. Adv Exp Med Biol. 2014; 810:282-302. Bikle DD. PMID: 25207372; PMCID: PMC9012606.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    96. LncRNA profiling reveals new mechanism for VDR protection against skin cancer formation. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:87-90. Jiang YJ, Bikle DD. PMID: 24342142.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    97. Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich, et al. Front Neuroendocrinol. 2014 Jan; 35(1):2-5. Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS. PMID: 24268499.
      View in: PubMed   Mentions:    Fields:    
    98. Variability in free 25(OH) vitamin D levels in clinical populations. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:156-8. Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D. PMID: 24240067; PMCID: PMC4022715.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    99. Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:237-41. Hu L, Bikle DD, Oda Y. PMID: 24239508; PMCID: PMC4061268.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    100. The protective role of vitamin d signaling in non-melanoma skin cancer. Cancers (Basel). 2013 Nov 05; 5(4):1426-38. Bikle DD, Jiang Y. PMID: 24202452; PMCID: PMC3875946.
      View in: PubMed   Mentions: 7  
    101. Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading. Acta Astronaut. 2013 Nov; 92(1):73-78. Kubota T, Elalieh HZ, Saless N, Fong C, Wang Y, Babey M, Cheng Z, Bikle DD. PMID: 23976802; PMCID: PMC3747570.
      View in: PubMed   Mentions: 10     Fields:    
    102. Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Eur J Endocrinol. 2013 Dec; 169(6):E1-4. Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS. PMID: 24057478.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    103. Autocrine and Paracrine Actions of IGF-I Signaling in Skeletal Development. Bone Res. 2013 Sep; 1(3):249-59. Wang Y, Bikle DD, Chang W. PMID: 26273506; PMCID: PMC4472106.
      View in: PubMed   Mentions: 34     Fields:    
    104. Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Endocrinology. 2013 Nov; 154(11):3957-60. Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS. PMID: 24048095; PMCID: PMC5398595.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    105. Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: superiority of free 25-OH D levels in detecting relationships. J Clin Endocrinol Metab. 2013 Nov; 98(11):4400-9. Kane L, Moore K, Lütjohann D, Bikle D, Schwartz JB. PMID: 24030939; PMCID: PMC3816263.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    106. Fifteenth vitamin D workshop. J Steroid Biochem Mol Biol. 2013 Jul; 136:1-2. Norman AW, Bikle D, Bouillon R. PMID: 23768771; PMCID: PMC4102609.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    107. Mammary-specific ablation of the calcium-sensing receptor during lactation alters maternal calcium metabolism, milk calcium transport, and neonatal calcium accrual. Endocrinology. 2013 Sep; 154(9):3031-42. Mamillapalli R, VanHouten J, Dann P, Bikle D, Chang W, Brown E, Wysolmerski J. PMID: 23782944; PMCID: PMC3749485.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    108. Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor. Biochemistry. 2013 Jun 18; 52(24):4193-203. Nandhikonda P, Yasgar A, Baranowski AM, Sidhu PS, McCallum MM, Pawlak AJ, Teske K, Feleke B, Yuan NY, Kevin C, Bikle DD, Ayers SD, Webb P, Rai G, Simeonov A, Jadhav A, Maloney D, Arnold LA. PMID: 23713684; PMCID: PMC3724348.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    109. Vitamin D: beyond bone. Ann N Y Acad Sci. 2013 May; 1287:45-58. Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, Rutten E, Pittas AG, Boland R, Ferrucci L, Bikle DD. PMID: 23682710; PMCID: PMC3717170.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    110. Sex and age modify biochemical and skeletal manifestations of chronic hyperparathyroidism by altering target organ responses to Ca2+ and parathyroid hormone in mice. J Bone Miner Res. 2013 May; 28(5):1087-100. Cheng Z, Liang N, Chen TH, Li A, Santa Maria C, You M, Ho H, Song F, Bikle D, Tu C, Shoback D, Chang W. PMID: 23239173; PMCID: PMC3617088.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    111. Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function. Best Pract Res Clin Endocrinol Metab. 2013 Jun; 27(3):415-27. Tu CL, Bikle DD. PMID: 23856269; PMCID: PMC3713412.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    112. Anabolic effects of IGF-1 signaling on the skeleton. Front Endocrinol (Lausanne). 2013; 4:6. Tahimic CG, Wang Y, Bikle DD. PMID: 23382729; PMCID: PMC3563099.
      View in: PubMed   Mentions: 73     Fields:    
    113. Ceramides stimulate caspase-14 expression in human keratinocytes. Exp Dermatol. 2013 Feb; 22(2):113-8. Jiang YJ, Kim P, Uchida Y, Elias PM, Bikle DD, Grunfeld C, Feingold KR. PMID: 23362869; PMCID: PMC4099380.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    114. Protective actions of vitamin D in UVB induced skin cancer. Photochem Photobiol Sci. 2012 Dec; 11(12):1808-16. Bikle DD. PMID: 22990497; PMCID: PMC3501582.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    115. Vitamin D in cutaneous carcinogenesis: part II. J Am Acad Dermatol. 2012 Nov; 67(5):817.e1-11; quiz 827-8. Tang JY, Fu T, Lau C, Oh DH, Bikle DD, Asgari MM. PMID: 23062904; PMCID: PMC3706259.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    116. Vitamin D in cutaneous carcinogenesis: part I. J Am Acad Dermatol. 2012 Nov; 67(5):803.e1-12, quiz 815-6. Tang JY, Fu T, Lau C, Oh DH, Bikle DD, Asgari MM. PMID: 23062903; PMCID: PMC3688468.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    117. Simulated spaceflight produces a rapid and sustained loss of osteoprogenitors and an acute but transitory rise of osteoclast precursors in two genetic strains of mice. Am J Physiol Endocrinol Metab. 2012 Dec 01; 303(11):E1354-62. Shahnazari M, Kurimoto P, Boudignon BM, Orwoll BE, Bikle DD, Halloran BP. PMID: 23047986; PMCID: PMC3774081.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    118. Protective role of vitamin D signaling in skin cancer formation. J Steroid Biochem Mol Biol. 2013 Jul; 136:271-9. Bikle DD, Elalieh H, Welsh J, Oh D, Cleaver J, Teichert A. PMID: 23059470; PMCID: PMC3596439.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    119. 1α,25(OH)2-dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway. J Steroid Biochem Mol Biol. 2013 Jul; 136:229-32. Jiang YJ, Teichert AE, Fong F, Oda Y, Bikle DD. PMID: 23026511; PMCID: PMC4102608.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    120. Calcium regulation of keratinocyte differentiation. Expert Rev Endocrinol Metab. 2012 Jul; 7(4):461-472. Bikle DD, Xie Z, Tu CL. PMID: 23144648; PMCID: PMC3491811.
      View in: PubMed   Mentions: 122     Fields:    
    121. Vitamin D and bone. Curr Osteoporos Rep. 2012 Jun; 10(2):151-9. Bikle DD. PMID: 22544628; PMCID: PMC3688475.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimals
    122. Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone. Curr Mol Pharmacol. 2012 Jun; 5(2):135-42. Bikle DD, Wang Y. PMID: 21787292; PMCID: PMC3690777.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    123. Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function. J Invest Dermatol. 2012 Oct; 132(10):2350-2359. Tu CL, Crumrine DA, Man MQ, Chang W, Elalieh H, You M, Elias PM, Bikle DD. PMID: 22622426; PMCID: PMC3434298.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    124. PTH/PTHrP and vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection. Sci Transl Med. 2012 May 23; 4(135):135ra66. Muehleisen B, Bikle DD, Aguilera C, Burton DW, Sen GL, Deftos LJ, Gallo RL. PMID: 22623742; PMCID: PMC3725981.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    125. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev. 2012 Jun; 33(3):456-92. Rosen CJ, Adams JS, Bikle DD, Black DM, Demay MB, Manson JE, Murad MH, Kovacs CS. PMID: 22596255; PMCID: PMC3365859.
      View in: PubMed   Mentions: 269     Fields:    Translation:HumansAnimals
    126. Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators. J Med Chem. 2012 May 24; 55(10):4640-51. Nandhikonda P, Lynt WZ, McCallum MM, Ara T, Baranowski AM, Yuan NY, Pearson D, Bikle DD, Guy RK, Arnold LA. PMID: 22563729; PMCID: PMC3364162.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    127. Vitamin D receptor mediates DNA repair and is UV inducible in intact epidermis but not in cultured keratinocytes. J Invest Dermatol. 2012 Aug; 132(8):2097-100. Demetriou SK, Ona-Vu K, Teichert AE, Cleaver JE, Bikle DD, Oh DH. PMID: 22495177; PMCID: PMC3396713.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    128. Vitamin D and the skin: Physiology and pathophysiology. Rev Endocr Metab Disord. 2012 Mar; 13(1):3-19. Bikle DD. PMID: 21845365; PMCID: PMC3687803.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    129. SERCA2-controlled Ca²+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier's disease. J Invest Dermatol. 2012 Apr; 132(4):1188-95. Celli A, Mackenzie DS, Zhai Y, Tu CL, Bikle DD, Holleran WM, Uchida Y, Mauro TM. PMID: 22277942; PMCID: PMC3305850.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    130. Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations. J Invest Dermatol. 2012 Apr; 132(4):1075-83. Oda Y, Hu L, Bul V, Elalieh H, Reddy JK, Bikle DD. PMID: 22189783; PMCID: PMC3400544.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    131. Osteoblast extracellular Ca2+ -sensing receptor regulates bone development, mineralization, and turnover. J Bone Miner Res. 2011 Dec; 26(12):2935-47. Dvorak-Ewell MM, Chen TH, Liang N, Garvey C, Liu B, Tu C, Chang W, Bikle DD, Shoback DM. PMID: 21956637; PMCID: PMC3222747.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    132. Skeletal unloading-induced insulin-like growth factor 1 (IGF-1) nonresponsiveness is not shared by platelet-derived growth factor: the selective role of integrins in IGF-1 signaling. J Bone Miner Res. 2011 Dec; 26(12):2948-58. Long RK, Nishida S, Kubota T, Wang Y, Sakata T, Elalieh HZ, Halloran BP, Bikle DD. PMID: 21932337; PMCID: PMC3222734.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    133. Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium. J Biol Chem. 2012 Jan 06; 287(2):1158-67. Rey O, Chang W, Bikle D, Rozengurt N, Young SH, Rozengurt E. PMID: 22094462; PMCID: PMC3256874.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    134. Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice. J Invest Dermatol. 2011 Nov; 131(11):2289-97. Teichert AE, Elalieh H, Elias PM, Welsh J, Bikle DD. PMID: 21814234; PMCID: PMC3193543.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    135. IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway. J Bone Miner Res. 2011 Jul; 26(7):1437-46. Wang Y, Cheng Z, Elalieh HZ, Nakamura E, Nguyen MT, Mackem S, Clemens TL, Bikle DD, Chang W. PMID: 21312270; PMCID: PMC3530140.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    136. Vitamin D metabolism and function in the skin. Mol Cell Endocrinol. 2011 Dec 05; 347(1-2):80-9. Bikle DD. PMID: 21664236; PMCID: PMC3188673.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    137. Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas. Cancer Prev Res (Phila). 2011 May; 4(5):744-51. Tang JY, Xiao TZ, Oda Y, Chang KS, Shpall E, Wu A, So PL, Hebert J, Bikle D, Epstein EH. PMID: 21436386; PMCID: PMC3088781.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    138. The calcium-sensing receptor-dependent regulation of cell-cell adhesion and keratinocyte differentiation requires Rho and filamin A. J Invest Dermatol. 2011 May; 131(5):1119-28. Tu CL, Chang W, Bikle DD. PMID: 21209619; PMCID: PMC3078217.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    139. Vitamin D regulation of immune function. Vitam Horm. 2011; 86:1-21. Bikle DD. PMID: 21419265.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    140. Vitamin D: an ancient hormone. Exp Dermatol. 2011 Jan; 20(1):7-13. Bikle DD. PMID: 21197695.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    141. The vitamin D receptor: a tumor suppressor in skin. Discov Med. 2011 Jan; 11(56):7-17. Bikle DD. PMID: 21276406; PMCID: PMC4113511.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    142. Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis. Br J Dermatol. 2011 Jan; 164(1):16-25. Celli A, Mackenzie DS, Crumrine DS, Tu CL, Hupe M, Bikle DD, Elias PM, Mauro TM. PMID: 20846312; PMCID: PMC3010253.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    143. Lineage-specific effects of 1,25-dihydroxyvitamin D(3) on the development of effector CD4 T cells. J Biol Chem. 2011 Jan 14; 286(2):997-1004. Palmer MT, Lee YK, Maynard CL, Oliver JR, Bikle DD, Jetten AM, Weaver CT. PMID: 21047796; PMCID: PMC3020784.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    144. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice. J Cell Physiol. 2010 Nov; 225(2):482-9. Teichert A, Elalieh H, Bikle D. PMID: 20458748; PMCID: PMC4103951.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    145. The transcriptional coactivator DRIP/mediator complex is involved in vitamin D receptor function and regulates keratinocyte proliferation and differentiation. J Invest Dermatol. 2010 Oct; 130(10):2377-88. Oda Y, Chalkley RJ, Burlingame AL, Bikle DD. PMID: 20520624; PMCID: PMC4114506.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    146. Differential regulation of epidermal function by VDR coactivators. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):308-13. Bikle DD, Teichert A, Arnold LA, Uchida Y, Elias PM, Oda Y. PMID: 20298785; PMCID: PMC2906691.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    147. Vitamin D: newly discovered actions require reconsideration of physiologic requirements. Trends Endocrinol Metab. 2010 Jun; 21(6):375-84. Bikle DD. PMID: 20149679; PMCID: PMC2880203.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimals
    148. Vitamin D and the skin. J Bone Miner Metab. 2010 Mar; 28(2):117-30. Bikle DD. PMID: 20107849.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    149. Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma. J Invest Dermatol. 2010 May; 130(5):1438-43. Asgari MM, Tang J, Warton ME, Chren MM, Quesenberry CP, Bikle D, Horst RL, Orentreich N, Vogelman JH, Friedman GD. PMID: 20043012; PMCID: PMC2855394.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansPHPublic Health
    150. Vitamin D and immune function: understanding common pathways. Curr Osteoporos Rep. 2009 Jul; 7(2):58-63. Bikle DD. PMID: 19631030.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    151. Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review. J Bone Miner Res. 2009 Jun; 24(6):1135-9. Pao VY, Chang S, Shoback DM, Bikle DD. PMID: 19113910; PMCID: PMC6956690.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    152. Quantification of the vitamin D receptor-coregulator interaction. Biochemistry. 2009 Feb 24; 48(7):1454-61. Teichert A, Arnold LA, Otieno S, Oda Y, Augustinaite I, Geistlinger TR, Kriwacki RW, Guy RK, Bikle DD. PMID: 19183053; PMCID: PMC2654718.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    153. Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. Mol Biol Cell. 2009 Mar; 20(6):1695-704. Xie Z, Chang SM, Pennypacker SD, Liao EY, Bikle DD. PMID: 19158393; PMCID: PMC2655244.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    154. Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation. J Invest Dermatol. 2009 Jun; 129(6):1367-78. Oda Y, Uchida Y, Moradian S, Crumrine D, Elias PM, Bikle DD. PMID: 19052561; PMCID: PMC2843519.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    155. Nonclassic actions of vitamin D. J Clin Endocrinol Metab. 2009 Jan; 94(1):26-34. Bikle D. PMID: 18854395; PMCID: PMC2630868.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimals
    156. Vitamin D receptor, UVR, and skin cancer: a potential protective mechanism. J Invest Dermatol. 2008 Oct; 128(10):2357-61. Bikle DD. PMID: 18787544; PMCID: PMC9017605.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    157. The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2008 Sep 02; 1(35):ra1. Chang W, Tu C, Chen TH, Bikle D, Shoback D. PMID: 18765830; PMCID: PMC3538864.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    158. Vitamin D and the immune system: role in protection against bacterial infection. Curr Opin Nephrol Hypertens. 2008 Jul; 17(4):348-52. Bikle DD. PMID: 18660668.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    159. Growth hormone/insulin-like growth factor-1/PTH axis in bone. J Bone Miner Res. 2008 May; 23(5):581-3. Bikle DD. PMID: 18433295.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    160. Integrins, insulin like growth factors, and the skeletal response to load. Osteoporos Int. 2008 Sep; 19(9):1237-46. Bikle DD. PMID: 18373051; PMCID: PMC9005159.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    161. Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes. J Biol Chem. 2008 Feb 08; 283(6):3519-3528. Tu CL, Chang W, Xie Z, Bikle DD. PMID: 18065418.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    162. Vitamin D insufficiency/deficiency in gastrointestinal disorders. J Bone Miner Res. 2007 Dec; 22 Suppl 2:V50-4. Bikle DD. PMID: 18290722.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    163. Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. J Invest Dermatol. 2008 Apr; 128(4):816-24. Schauber J, Oda Y, Büchau AS, Yun QC, Steinmeyer A, Zügel U, Bikle DD, Gallo RL. PMID: 17943182.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    164. IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone. J Bone Miner Res. 2007 Sep; 22(9):1329-37. Wang Y, Nishida S, Boudignon BM, Burghardt A, Elalieh HZ, Hamilton MM, Majumdar S, Halloran BP, Clemens TL, Bikle DD. PMID: 17539737; PMCID: PMC10702248.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    165. What is new in vitamin D: 2006-2007. Curr Opin Rheumatol. 2007 Jul; 19(4):383-8. Bikle DD. PMID: 17551371.
      View in: PubMed   Mentions: 26  Translation:HumansAnimalsCells
    166. Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading. J Appl Physiol (1985). 2007 Jul; 103(1):125-31. Boudignon BM, Bikle DD, Kurimoto P, Elalieh H, Nishida S, Wang Y, Burghardt A, Majumdar S, Orwoll BE, Rosen C, Halloran BP. PMID: 17412794.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    167. Constitutive activity of the osteoblast Ca2+-sensing receptor promotes loss of cancellous bone. Endocrinology. 2007 Jul; 148(7):3156-63. Dvorak MM, Chen TH, Orwoll B, Garvey C, Chang W, Bikle DD, Shoback DM. PMID: 17412806.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    168. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest. 2007 Mar; 117(3):803-11. Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle DD, Modlin RL, Gallo RL. PMID: 17290304; PMCID: PMC1784003.
      View in: PubMed   Mentions: 266     Fields:    Translation:HumansAnimalsCells
    169. The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation. J Biol Chem. 2007 Mar 23; 282(12):8695-703. Xie Z, Bikle DD. PMID: 17242406.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    170. Sequential regulation of keratinocyte differentiation by 1,25(OH)2D3, VDR, and its coregulators. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):396-404. Bikle D, Teichert A, Hawker N, Xie Z, Oda Y. PMID: 17229570.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    171. Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):776-80. Oda Y, Ishikawa MH, Hawker NP, Yun QC, Bikle DD. PMID: 17223341.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    172. The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol. 2007 May; 127(5):1074-83. Tu CL, Chang W, Bikle DD. PMID: 17124506.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    173. Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3. J Invest Dermatol. 2007 Apr; 127(4):874-80. Hawker NP, Pennypacker SD, Chang SM, Bikle DD. PMID: 17082781.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    174. Role of IGF-I signaling in regulating osteoclastogenesis. J Bone Miner Res. 2006 Sep; 21(9):1350-8. Wang Y, Nishida S, Elalieh HZ, Long RK, Halloran BP, Bikle DD. PMID: 16939393; PMCID: PMC10723110.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    175. Evaluation of fetal bone structure and mineralization in IGF-I deficient mice using synchrotron radiation microtomography and Fourier transform infrared spectroscopy. Bone. 2007 Jan; 40(1):160-8. Burghardt AJ, Wang Y, Elalieh H, Thibault X, Bikle D, Peyrin F, Majumdar S. PMID: 16905376.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    176. Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology. 2006 Oct; 147(10):4753-61. Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD. PMID: 16857753; PMCID: PMC10645399.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    177. Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I. J Endocrinol. 2006 May; 189(2):279-87. Wang Y, Sakata T, Elalieh HZ, Munson SJ, Burghardt A, Majumdar S, Halloran BP, Bikle DD. PMID: 16648295; PMCID: PMC10745196.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    178. Development and progression of alopecia in the vitamin D receptor null mouse. J Cell Physiol. 2006 May; 207(2):340-53. Bikle DD, Elalieh H, Chang S, Xie Z, Sundberg JP. PMID: 16419036.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    179. Hairless suppresses vitamin D receptor transactivation in human keratinocytes. Endocrinology. 2006 Jan; 147(1):314-23. Xie Z, Chang S, Oda Y, Bikle DD. PMID: 16269453.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    180. Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes. Endocrinology. 2005 Dec; 146(12):5294-303. Rodriguez L, Tu C, Cheng Z, Chen TH, Bikle D, Shoback D, Chang W. PMID: 16166224.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    181. Vitamin D and skin cancer: a problem in gene regulation. J Steroid Biochem Mol Biol. 2005 Oct; 97(1-2):83-91. Bikle DD, Oda Y, Xie Z. PMID: 16039846.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    182. Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1. Mol Biol Cell. 2005 Jul; 16(7):3236-46. Xie Z, Singleton PA, Bourguignon LY, Bikle DD. PMID: 15872086; PMCID: PMC1165407.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    183. Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes. J Invest Dermatol. 2005 Jan; 124(1):187-97. Tu CL, Chang W, Bikle DD. PMID: 15654973.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    184. Vitamin D and skin cancer. J Nutr. 2004 12; 134(12 Suppl):3472S-3478S. Bikle DD. PMID: 15570056.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    185. The effect of LXR activators on AP-1 proteins in keratinocytes. J Invest Dermatol. 2004 Jul; 123(1):41-8. Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR. PMID: 15191540.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    186. Vitamin D regulated keratinocyte differentiation. J Cell Biochem. 2004 Jun 01; 92(3):436-44. Bikle DD. PMID: 15156556.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    187. Mice lacking 25OHD 1alpha-hydroxylase demonstrate decreased epidermal differentiation and barrier function. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):347-53. Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM. PMID: 15225799.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    188. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):273-6. Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. PMID: 15225784.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    189. Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):355-60. Bikle DD, Oda Y, Xie Z. PMID: 15225800.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    190. 25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis. J Invest Dermatol. 2004 Apr; 122(4):984-92. Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM. PMID: 15102089.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    191. The role of the calcium-sensing receptor in epidermal differentiation. Cell Calcium. 2004 Mar; 35(3):265-73. Tu CL, Oda Y, Komuves L, Bikle DD. PMID: 15200150.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    192. Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways. J Bone Miner Res. 2004 Mar; 19(3):436-46. Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, Bikle DD. PMID: 15040832; PMCID: PMC10720400.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    193. PTH differentially regulates expression of RANKL and OPG. J Bone Miner Res. 2004 Feb; 19(2):235-44. Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA. PMID: 14969393.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    194. Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores. J Invest Dermatol. 2003 Oct; 121(4):688-94. Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM. PMID: 14632183.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    195. bFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells. Calcif Tissue Int. 2003 Aug; 73(2):147-52. Nauman EA, Sakata T, Keaveny TM, Halloran BP, Bikle DD. PMID: 14565596.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    196. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation. Mol Endocrinol. 2003 Nov; 17(11):2329-39. Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. PMID: 12893881.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    197. Skeletal unloading induces resistance to insulin-like growth factor I on bone formation. Bone. 2003 Jun; 32(6):669-80. Sakata T, Halloran BP, Elalieh HZ, Munson SJ, Rudner L, Venton L, Ginzinger D, Rosen CJ, Bikle DD. PMID: 12810174.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    198. The impact of skeletal unloading on bone formation. Gravit Space Biol Bull. 2003 Jun; 16(2):45-54. Bikle DD, Sakata T, Halloran BP. PMID: 12959131.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    199. Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma. J Cell Physiol. 2003 May; 195(2):249-59. Yang LC, Ng DC, Bikle DD. PMID: 12652652.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    200. Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate. J Cell Biochem. 2003 Mar 01; 88(4):732-43. Dolezalova H, Shankar G, Huang MC, Bikle DD, Goetzl EJ. PMID: 12577307.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    201. Vitamin D regulated keratinocyte differentiation: role of coactivators. J Cell Biochem. 2003 Feb 01; 88(2):290-5. Bikle DD, Tu CL, Xie Z, Oda Y. PMID: 12520529.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    202. Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why? Recent Results Cancer Res. 2003; 164:111-22. Bikle DD, Xie Z, Ng D, Tu CL, Oda Y. PMID: 12899516.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    203. Mechanical and chemical characteristics of mineral produced by basic fibroblast growth factor-treated bone marrow stromal cells in vitro. Tissue Eng. 2002 Dec; 8(6):931-9. Nauman EA, Ebenstein DM, Hughes KF, Pruitt L, Halloran BP, Bikle DD, Keaveny TM. PMID: 12542939.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    204. The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3. J Invest Dermatol. 2002 Nov; 119(5):1109-13. Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z. PMID: 12445200.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    205. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. J Bone Miner Res. 2002 Sep; 17(9):1570-8. Bikle DD, Sakata T, Leary C, Elalieh H, Ginzinger D, Rosen CJ, Beamer W, Majumdar S, Halloran BP. PMID: 12211426.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    206. Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation. J Cell Physiol. 2002 Jul; 192(1):45-54. Komuves L, Oda Y, Tu CL, Chang WH, Ho-Pao CL, Mauro T, Bikle DD. PMID: 12115735.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    207. The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes. J Biol Chem. 2002 Oct 04; 277(40):36987-90. Xie Z, Munson SJ, Huang N, Portale AA, Miller WL, Bikle DD. PMID: 11956203.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    208. Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol. 2002 Jan; 118(1):11-6. Xie Z, Komuves L, Yu QC, Elalieh H, Ng DC, Leary C, Chang S, Crumrine D, Yoshizawa T, Kato S, Bikle DD. PMID: 11851870.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    209. The skeletal structure of insulin-like growth factor I-deficient mice. J Bone Miner Res. 2001 Dec; 16(12):2320-9. Bikle D, Majumdar S, Laib A, Powell-Braxton L, Rosen C, Beamer W, Nauman E, Leary C, Halloran B. PMID: 11760848.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    210. Inhibition of 1,25-dihydroxyvitamin-D-induced keratinocyte differentiation by blocking the expression of phospholipase C-gamma1. J Invest Dermatol. 2001 Nov; 117(5):1250-4. Xie Z, Bikle DD. PMID: 11710940.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    211. The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes. J Biol Chem. 2001 Nov 02; 276(44):41079-85. Tu CL, Chang W, Bikle DD. PMID: 11500521.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    212. Calcium- and vitamin D-regulated keratinocyte differentiation. Mol Cell Endocrinol. 2001 May 25; 177(1-2):161-71. Bikle DD, Ng D, Tu CL, Oda Y, Xie Z. PMID: 11377831.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    213. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. J Appl Physiol (1985). 2001 May; 90(5):1849-54. Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD. PMID: 11299276.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    214. Selective inhibition of vitamin D hydroxylases in human keratinocytes. Steroids. 2001 Mar-May; 66(3-5):409-22. Schuster I, Egger H, Bikle D, Herzig G, Reddy GS, Stuetz A, Stuetz P, Vorisek G. PMID: 11179750.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    215. The role of phospholipase C-gamma1 in 1alpha,25-dihydroxyvitamin D(3) regulated keratinocyte differentiation. Steroids. 2001 Mar-May; 66(3-5):339-45. Xie Z, Bikle DD. PMID: 11179742.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    216. Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D. J Lipid Res. 2001 Mar; 42(3):390-8. Hanley K, Wood L, Ng DC, He SS, Lau P, Moser A, Elias PM, Bikle DD, Williams ML, Feingold KR. PMID: 11254751.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    217. Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo. J Invest Dermatol. 2000 Sep; 115(3):353-60. Kömüves LG, Hanley K, Lefebvre AM, Man MQ, Ng DC, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR. PMID: 10951268.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    218. Requirement of an AP-1 site in the calcium response region of the involucrin promoter. J Biol Chem. 2000 Aug 04; 275(31):24080-8. Ng DC, Shafaee S, Lee D, Bikle DD. PMID: 10816578.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    219. Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. J Biol Chem. 2000 Apr 14; 275(15):11484-91. Hanley K, Kömüves LG, Ng DC, Schoonjans K, He SS, Lau P, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR. PMID: 10753967.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    220. Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. J Invest Dermatol. 2000 Mar; 114(3):545-53. Hanley K, Ng DC, He SS, Lau P, Min K, Elias PM, Bikle DD, Mangelsdorf DJ, Williams ML, Feingold KR. PMID: 10692116.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    221. The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation. J Biol Chem. 2000 Jan 14; 275(2):1183-90. Oda Y, Tu CL, Chang W, Crumrine D, Kömüves L, Mauro T, Elias PM, Bikle DD. PMID: 10625662.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    222. Effects of a calcium receptor activator on the cellular response to calcium in human keratinocytes. J Invest Dermatol. 1999 Sep; 113(3):340-5. Tu CL, Oda Y, Bikle DD. PMID: 10469331.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    223. Phospholipase C-gamma1 is required for calcium-induced keratinocyte differentiation. J Biol Chem. 1999 Jul 16; 274(29):20421-4. Xie Z, Bikle DD. PMID: 10400667.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    224. Differences in calcium metabolism between black and white men and women. Miner Electrolyte Metab. 1999 May-Jun; 25(3):178-84. Bikle DD, Ettinger B, Sidney S, Tekawa IS, Tolan K. PMID: 10436403.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    225. 1,25 dihydroxyvitamin D3 enhances the calcium response of keratinocytes. J Cell Physiol. 1999 Feb; 178(2):188-96. Ratnam AV, Bikle DD, Cho JK. PMID: 10048583.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    226. Bone and hormonal changes induced by skeletal unloading in the mature male rat. Am J Physiol. 1999 Jan; 276(1 Pt 1):E62-9. Dehority W, Halloran BP, Bikle DD, Curren T, Kostenuik PJ, Wronski TJ, Shen Y, Rabkin B, Bouraoui A, Morey-Holton E. PMID: 9886951.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    227. The response of bone to unloading. J Bone Miner Metab. 1999; 17(4):233-44. Bikle DD, Halloran BP. PMID: 10575587.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimals
    228. Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I. J Bone Miner Res. 1999 Jan; 14(1):21-31. Kostenuik PJ, Harris J, Halloran BP, Turner RT, Morey-Holton ER, Bikle DD. PMID: 9893062.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    229. Six putative IQ motifs of the recombinant chicken intestinal brush border myosin I are involved in calmodulin binding. Arch Biochem Biophys. 1999 Jan 01; 361(1):94-100. Khoroshev MI, Munson SJ, Bikle DD. PMID: 9882432.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    230. The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation. J Biol Chem. 1998 Sep 04; 273(36):23344-52. Oda Y, Tu CL, Pillai S, Bikle DD. PMID: 9722568.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    231. Differential regulation of vitamin D responsive elements in normal and transformed keratinocytes. J Invest Dermatol. 1998 May; 110(5):730-3. Xie Z, Bikle DD. PMID: 9579536.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    232. Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha. J Invest Dermatol. 1998 Apr; 110(4):368-75. Hanley K, Jiang Y, He SS, Friedman M, Elias PM, Bikle DD, Williams ML, Feingold KR. PMID: 9540977.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    233. All-trans retinoic acid blocks the antiproliferative prodifferentiating actions of 1,25-dihydroxyvitamin D3 in normal human keratinocytes. J Cell Physiol. 1998 Jan; 174(1):1-8. Gibson DF, Bikle DD, Harris J. PMID: 9397150.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    234. Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1. Mol Endocrinol. 1997 Dec; 11(13):1961-70. Fu GK, Lin D, Zhang MY, Bikle DD, Shackleton CH, Miller WL, Portale AA. PMID: 9415400.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    235. Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells. Am J Physiol. 1997 Dec; 273(6 Pt 1):E1133-9. Kostenuik PJ, Halloran BP, Morey-Holton ER, Bikle DD. PMID: 9435529.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    236. Biochemical markers in the assessment of bone disease. Am J Med. 1997 Nov; 103(5):427-36. Bikle DD. PMID: 9375712.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    237. Vitamin D: a calciotropic hormone regulating calcium-induced keratinocyte differentiation. J Am Acad Dermatol. 1997 Sep; 37(3 Pt 2):S42-52. Bikle DD. PMID: 9344184.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    238. The expression of the gap junctional protein Cx43 is restricted to proliferating and non differentiated normal and transformed keratinocytes. Exp Dermatol. 1997 Aug; 6(4):167-74. Gibson DF, Bikle DD, Harris J, Goldberg GS. PMID: 9293388.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    239. Decrease of Ca(2+)-ATPase activity in human keratinocytes during calcium-induced differentiation. J Cell Physiol. 1997 Aug; 172(2):146-54. Cho JK, Bikle DD. PMID: 9258336.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    240. Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading. J Bone Miner Res. 1997 Jul; 12(7):1068-74. Halloran BP, Bikle DD, Harris J, Tanner S, Curren T, Morey-Holton E. PMID: 9200006.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    241. Spaceflight and the skeleton: lessons for the earthbound. Gravit Space Biol Bull. 1997 Jun; 10(2):119-35. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11540113.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    242. Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element. J Biol Chem. 1997 Mar 07; 272(10):6573-7. Xie Z, Bikle DD. PMID: 9045685.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    243. Racial differences in bone density between young adult black and white subjects persist after adjustment for anthropometric, lifestyle, and biochemical differences. J Clin Endocrinol Metab. 1997 Feb; 82(2):429-34. Ettinger B, Sidney S, Cummings SR, Libanati C, Bikle DD, Tekawa IS, Tolan K, Steiger P. PMID: 9024231.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    244. Space flight and the skeleton: lessons for the earthbound. Endocrinologist. 1997 Jan-Feb; 7(1):10-22. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11540416.
      View in: PubMed   Mentions: 7  Translation:HumansAnimals
    245. Antiestrogen potentiation of antiproliferative effects of vitamin D3 analogues in breast cancer cells. Cancer Res. 1996 Jun 15; 56(12):2789-94. Love-Schimenti CD, Gibson DF, Ratnam AV, Bikle DD. PMID: 8665515.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    246. Zipper protein, a B-G protein with the ability to regulate actin/myosin 1 interactions in the intestinal brush border. J Biol Chem. 1996 Apr 12; 271(15):9075-83. Bikle DD, Munson S, Komuves L. PMID: 8621557.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    247. 1,25(OH)2D3-modulated calcium induced keratinocyte differentiation. J Investig Dermatol Symp Proc. 1996 Apr; 1(1):22-7. Bikle DD. PMID: 9627687.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    248. Squamous carcinoma cell lines fail to respond to 1,25-Dihydroxyvitamin D despite normal levels of the vitamin D receptor. J Invest Dermatol. 1996 Mar; 106(3):522-5. Ratnam AV, Bikle DD, Su MJ, Pillai S. PMID: 8648187.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    249. Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor. J Clin Invest. 1996 Feb 15; 97(4):1085-93. Bikle DD, Ratnam A, Mauro T, Harris J, Pillai S. PMID: 8613532; PMCID: PMC507156.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    250. Evidence for separate control mechanisms at the message, protein, and enzyme activation levels for transglutaminase during calcium-induced differentiation of normal and transformed human keratinocytes. J Invest Dermatol. 1996 Jan; 106(1):154-61. Gibson DF, Ratnam AV, Bikle DD. PMID: 8592067.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    251. Regulation of involucrin gene expression by calcium in normal human keratinocytes. Front Biosci. 1996 Jan 01; 1:a16-24. Ng DC, Su MJ, Kim R, Bikle DD. PMID: 9159190.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    252. 22-Oxa calcitriol is a less potent regulator of keratinocyte proliferation and differentiation due to decreased cellular uptake and enhanced catabolism. J Invest Dermatol. 1995 Nov; 105(5):693-8. Bikle DD, Abe-Hashimoto J, Su MJ, Felt S, Gibson DF, Pillai S. PMID: 7594646.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    253. Skeletal unloading induces selective resistance to the anabolic actions of growth hormone on bone. J Bone Miner Res. 1995 Aug; 10(8):1168-76. Halloran BP, Bikle DD, Harris J, Autry CP, Currier PA, Tanner S, Patterson-Buckendahl P, Morey-Holton E. PMID: 8585419.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    254. 1,25-Dihydroxyvitamin D3 upregulates the phosphatidylinositol signaling pathway in human keratinocytes by increasing phospholipase C levels. J Clin Invest. 1995 Jul; 96(1):602-9. Pillai S, Bikle DD, Su MJ, Ratnam A, Abe J. PMID: 7615834; PMCID: PMC185235.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    255. 1,25(OH)2D3-regulated human keratinocyte proliferation and differentiation: basic studies and their clinical application. J Nutr. 1995 06; 125(6 Suppl):1709S-1714S. Bikle DD. PMID: 7782932.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    256. The molecular response of bone to growth hormone during skeletal unloading: regional differences. Endocrinology. 1995 May; 136(5):2099-109. Bikle DD, Harris J, Halloran BP, Currier PA, Tanner S, Morey-Holton E. PMID: 7720659.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    257. Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Ann Intern Med. 1995 Apr 01; 122(7):511-3. Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP. PMID: 7872586.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    258. Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation. Am J Physiol. 1994 Dec; 267(6 Pt 1):E822-7. Bikle DD, Harris J, Halloran BP, Morey-Holton E. PMID: 7810622.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    259. Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage. J Bone Miner Res. 1994 Nov; 9(11):1777-87. Bikle DD, Morey-Holton ER, Doty SB, Currier PA, Tanner SJ, Halloran BP. PMID: 7863829.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    260. Skeletal unloading induces resistance to insulin-like growth factor I. J Bone Miner Res. 1994 Nov; 9(11):1789-96. Bikle DD, Harris J, Halloran BP, Morey-Holton ER. PMID: 7532347.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    261. Role of vitamin D, its metabolites, and analogs in the management of osteoporosis. Rheum Dis Clin North Am. 1994 Aug; 20(3):759-75. Bikle DD. PMID: 7984788.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    262. Expression of the genes for insulin-like growth factors and their receptors in bone during skeletal growth. Am J Physiol. 1994 Aug; 267(2 Pt 1):E278-86. Bikle DD, Harris J, Halloran BP, Roberts CT, Leroith D, Morey-Holton E. PMID: 8074208.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    263. Impact of skeletal unloading on bone formation: role of systemic and local factors. Acta Astronaut. 1994 Jul; 33:119-29. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11539511.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    264. 1,25-Dihydroxyvitamin D3 potentiates the keratinocyte response to calcium. J Biol Chem. 1994 May 20; 269(20):14723-9. Su MJ, Bikle DD, Mancianti ML, Pillai S. PMID: 7910167.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    265. Production of 1,25 dihydroxyvitamin D3 by perfused pig skin. J Invest Dermatol. 1994 May; 102(5):796-8. Bikle DD, Halloran BP, Riviere JE. PMID: 8176265.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    266. Regulation of calmodulin binding to the ATP extractable 110 kDa protein (myosin I) from chicken duodenal brush border by 1,25-(OH)2D3. Biochim Biophys Acta. 1994 Mar 23; 1190(2):329-36. Kaune R, Munson S, Bikle DD. PMID: 8142433.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    267. Regulation of keratinocyte growth, differentiation, and vitamin D metabolism by analogs of 1,25-dihydroxyvitamin D. J Invest Dermatol. 1993 Nov; 101(5):713-8. Bikle DD, Gee E, Pillai S. PMID: 8228333.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    268. Alcohol-induced bone disease: relationship to age and parathyroid hormone levels. Alcohol Clin Exp Res. 1993 Jun; 17(3):690-5. Bikle DD, Stesin A, Halloran B, Steinbach L, Recker R. PMID: 8333602.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    269. Skeletal unloading decreases production of 1,25-dihydroxyvitamin D. Am J Physiol. 1993 May; 264(5 Pt 1):E712-6. Halloran BP, Bikle DD, Harris J, Foskett HC, Morey-Holton E. PMID: 8498493.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    270. Elevated 1,25-dihydroxyvitamin D levels in patients with chronic obstructive pulmonary disease treated with prednisone. J Clin Endocrinol Metab. 1993 Feb; 76(2):456-61. Bikle DD, Halloran B, Fong L, Steinbach L, Shellito J. PMID: 8432789.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    271. Vitamin D, calcium, and epidermal differentiation. Endocr Rev. 1993 Feb; 14(1):3-19. Bikle DD, Pillai S. PMID: 8491153.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    272. Zipper protein, a newly described tropomyosin-like protein of the intestinal brush border. J Biol Chem. 1993 Jan 05; 268(1):620-6. Bikle DD, Munson S, Morrison N, Eisman J. PMID: 7678004.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    273. Localization and quantitation of calcium pools and calcium binding sites in cultured human keratinocytes. J Cell Physiol. 1993 Jan; 154(1):101-12. Pillai S, Menon GK, Bikle DD, Elias PM. PMID: 8419397.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    274. Alcohol-induced bone disease. World Rev Nutr Diet. 1993; 73:53-79. Bikle DD. PMID: 8367983.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    275. Metabolic acidosis reverses the increase in serum 1,25(OH)2D in phosphorus-restricted normal men. Am J Physiol. 1992 12; 263(6):E1164-70. Portale AA, Halloran BP, Harris ST, Bikle DD, Morris RC. PMID: 1476189.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    276. Clinical counterpoint: vitamin D: new actions, new analogs, new therapeutic potential. Endocr Rev. 1992 Nov; 13(4):765-84. Bikle DD. PMID: 1459048.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    277. Progestin antagonism of estrogen stimulated 1,25-dihydroxyvitamin D levels. J Clin Endocrinol Metab. 1992 Aug; 75(2):519-23. Bikle DD, Halloran BP, Harris ST, Portale AA. PMID: 1639954.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    278. Effects of dietary protein deficiency on mineral metabolism and bone mineral density. Am J Clin Nutr. 1992 Aug; 56(2):314-9. Orwoll E, Ware M, Stribrska L, Bikle D, Sanchez T, Andon M, Li H. PMID: 1636610.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    279. Adenosine triphosphate stimulates phosphoinositide metabolism, mobilizes intracellular calcium, and inhibits terminal differentiation of human epidermal keratinocytes. J Clin Invest. 1992 Jul; 90(1):42-51. Pillai S, Bikle DD. PMID: 1321844; PMCID: PMC443061.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    280. Lanthanum influx into cultured human keratinocytes: effect on calcium flux and terminal differentiation. J Cell Physiol. 1992 Jun; 151(3):623-9. Pillai S, Bikle DD. PMID: 1363554.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    281. Squamous carcinoma cell lines produce 1,25 dihydroxyvitamin D, but fail to respond to its prodifferentiating effect. J Invest Dermatol. 1991 Sep; 97(3):435-41. Bikle DD, Pillai S, Gee E. PMID: 1875043.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    282. Tumor necrosis factor-alpha regulation of 1,25-dihydroxyvitamin D production by human keratinocytes. Endocrinology. 1991 Jul; 129(1):33-8. Bikle DD, Pillai S, Gee E, Hincenbergs M. PMID: 1675987.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    283. Uncoupling of the calcium-sensing mechanism and differentiation in squamous carcinoma cell lines. Exp Cell Res. 1991 Feb; 192(2):567-73. Pillai S, Bikle DD, Mancianti ML, Hincenbergs M. PMID: 1988295.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    284. Limited tissue distribution of the intestinal brush border myosin I protein. Gastroenterology. 1991 Feb; 100(2):395-402. Bikle DD, Munson S, Mancianti ML. PMID: 1985037.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    285. Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: differences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3. J Cell Physiol. 1991 Jan; 146(1):94-100. Pillai S, Bikle DD. PMID: 1990023.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    286. Epidermal vitamin D metabolism, function, and regulation. Adv Lipid Res. 1991; 24:321-41. Pillai S, Bikle DD. PMID: 1763717.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    287. Different responses of trabecular and cortical bone to 1,25(OH)2D3 infusion. Am J Physiol. 1990 Nov; 259(5 Pt 1):E715-22. Bikle DD, Halloran BP, McGalliard-Cone C, Morey-Holton E. PMID: 2240210.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    288. Calcium regulation of growth and differentiation of normal human keratinocytes: modulation of differentiation competence by stages of growth and extracellular calcium. J Cell Physiol. 1990 May; 143(2):294-302. Pillai S, Bikle DD, Mancianti ML, Cline P, Hincenbergs M. PMID: 1970572.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    289. Serum vitamin D metabolites are not responsible for low turnover osteoporosis in chronic liver disease. J Clin Endocrinol Metab. 1989 Dec; 69(6):1234-9. Diamond T, Stiel D, Mason R, Lissner D, Bikle D, Wilson S, Posen S. PMID: 2584358.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    290. Effects of simulated weightlessness on rat osteocalcin and bone calcium. Am J Physiol. 1989 Nov; 257(5 Pt 2):R1103-9. Patterson-Buckendahl P, Globus RK, Bikle DD, Cann CE, Morey-Holton E. PMID: 2589536.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    291. Bone response to normal weight bearing after a period of skeletal unloading. Am J Physiol. 1989 Oct; 257(4 Pt 1):E606-10. Sessions ND, Halloran BP, Bikle DD, Wronski TJ, Cone CM, Morey-Holton E. PMID: 2801939.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    292. Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis. J Clin Invest. 1989 May; 83(5):1527-32. Barnes PF, Modlin RL, Bikle DD, Adams JS. PMID: 2540219; PMCID: PMC303857.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    293. Binding and biological effects of tumor necrosis factor alpha on cultured human neonatal foreskin keratinocytes. J Clin Invest. 1989 Mar; 83(3):816-21. Pillai S, Bikle DD, Eessalu TE, Aggarwal BB, Elias PM. PMID: 2466051; PMCID: PMC303753.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    294. Isotopic labeling affects 1,25-dihydroxyvitamin D metabolism. Biochemistry. 1989 Feb 07; 28(3):1278-81. Halloran BP, Bikle DD, Castro ME, Gee E. PMID: 2713363.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    295. Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes. Endocrinology. 1989 Feb; 124(2):649-54. Bikle DD, Gee E. PMID: 2463902.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    296. Regulation of 1,25-dihydroxyvitamin D production in human keratinocytes by interferon-gamma. Endocrinology. 1989 Feb; 124(2):655-60. Bikle DD, Pillai S, Gee E, Hincenbergs M. PMID: 2463903.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    297. Calmodulin binding to the intestinal brush-border membrane: comparison to other calcium-binding proteins. Biochim Biophys Acta. 1989 Jan 17; 1010(1):122-7. Bikle D, Munson S, Christakos S, Kumar R, Buckendahl P. PMID: 2909247.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    298. Glucocorticoids and inhibition of bone formation induced by skeletal unloading. Am J Physiol. 1988 Dec; 255(6 Pt 1):E875-9. Halloran BP, Bikle DD, Cone CM, Morey-Holton E. PMID: 3202163.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    299. Serum dihydrotachysterol levels and biological action in normal man. J Clin Endocrinol Metab. 1988 Jul; 67(1):198-202. Taylor A, Bikle DD, Norman ME. PMID: 3379133.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    300. 1,25-Dihydroxyvitamin D production and receptor binding in human keratinocytes varies with differentiation. J Biol Chem. 1988 Apr 15; 263(11):5390-5. Pillai S, Bikle DD, Elias PM. PMID: 2451669.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    301. Biochemical and morphological characterization of growth and differentiation of normal human neonatal keratinocytes in a serum-free medium. J Cell Physiol. 1988 Feb; 134(2):229-37. Pillai S, Bikle DD, Hincenbergs M, Elias PM. PMID: 2450102.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    302. Effects of alcohol abuse on bone. Compr Ther. 1988 Feb; 14(2):16-20. Bikle DD. PMID: 3278834.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    303. Vitamin D and epidermal differentiation: evidence for a role of endogenously produced vitamin D metabolites in keratinocyte differentiation. Skin Pharmacol. 1988; 1(3):149-60. Pillai S, Bikle DD, Elias PM. PMID: 3078531.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    304. Vitamin D metabolite production and function in keratinocytes. Ann N Y Acad Sci. 1988; 548:27-44. Bikle DD, Pillai S. PMID: 2470300.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    305. The effect of vitamin D status on cutaneous sterologenesis in vivo and in vitro. Biochim Biophys Acta. 1987 Sep 14; 930(2):193-200. Feingold KR, Williams ML, Pillai S, Menon GK, Halloran BP, Bikle DD, Elias PM. PMID: 3040120.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    306. Effect of dietary acid and calcium on 25-hydroxyvitamin D metabolism by chick kidney. J Bone Miner Res. 1987 Aug; 2(4):289-96. Cunningham J, Bikle DD, Avioli LV. PMID: 3455615.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    307. The effects of simulated weightlessness on bone maturation. Endocrinology. 1987 Feb; 120(2):678-84. Bikle DD, Halloran BP, Cone CM, Globus RK, Morey-Holton E. PMID: 3803298.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    308. Chronic administration of 1,25-dihydroxyvitamin D3: increased bone but impaired mineralization. Endocrinology. 1986 Dec; 119(6):2580-5. Wronski TJ, Halloran BP, Bikle DD, Globus RK, Morey-Holton ER. PMID: 3780540.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    309. Stimulation by 1,25-dihydroxyvitamin D3 of adenylate cyclase along the villus of chick duodenum. Endocrinology. 1986 Dec; 119(6):2568-73. Long RG, Bikle DD, Munson SJ. PMID: 3780539.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    310. Effect of ethanol on intestinal calcium transport in chicks. Gastroenterology. 1986 Oct; 91(4):870-6. Bikle DD, Gee EA, Munson SJ. PMID: 3743964.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    311. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J Clin Endocrinol Metab. 1986 Oct; 63(4):954-9. Bikle DD, Gee E, Halloran B, Kowalski MA, Ryzen E, Haddad JG. PMID: 3745408.
      View in: PubMed   Mentions: 273     Fields:    Translation:HumansCells
    312. Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. J Clin Invest. 1986 Sep; 78(3):748-52. Bikle DD, Halloran BP, Gee E, Ryzen E, Haddad JG. PMID: 3745436; PMCID: PMC423667.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    313. Chronic 1,25-dihydroxyvitamin D3 administration in the rat reduces the serum concentration of 25-hydroxyvitamin D by increasing metabolic clearance rate. J Clin Invest. 1986 Sep; 78(3):622-8. Halloran BP, Bikle DD, Levens MJ, Castro ME, Globus RK, Holton E. PMID: 3489007; PMCID: PMC423635.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    314. 1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation. J Clin Invest. 1986 Aug; 78(2):557-66. Bikle DD, Nemanic MK, Gee E, Elias P. PMID: 2426308; PMCID: PMC423594.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    315. Neonatal human foreskin keratinocytes produce 1,25-dihydroxyvitamin D3. Biochemistry. 1986 Apr 08; 25(7):1545-8. Bikle DD, Nemanic MK, Whitney JO, Elias PW. PMID: 2423114.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    316. Skeletal response to dietary calcium in a rat model simulating weightlessness. J Bone Miner Res. 1986 Apr; 1(2):191-7. Globus RK, Bikle DD, Halloran B, Morey-Holton E. PMID: 3503537.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    317. The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading. Endocrinology. 1986 Mar; 118(3):948-54. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. PMID: 3485043.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    318. The temporal response of bone to unloading. Endocrinology. 1986 Feb; 118(2):733-42. Globus RK, Bikle DD, Morey-Holton E. PMID: 3943489.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    319. The villus gradient of brush border membrane calmodulin and the calcium-independent calmodulin-binding protein parallels that of calcium-accumulating ability. Endocrinology. 1986 Feb; 118(2):727-32. Bikle DD, Munson S. PMID: 3753677.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    320. 1,25-Dihydroxyvitamin D increases calmodulin binding to specific proteins in the chick duodenal brush border membrane. J Clin Invest. 1985 Dec; 76(6):2312-6. Bikle DD, Munson S. PMID: 3841129; PMCID: PMC424356.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    321. Bone loss during simulated weightlessness: is it glucocorticoid mediated? Physiologist. 1985 Dec; 28(6 Suppl):S123-4. Bikle DD, Halloran BP, Cone CM, Morey-Holton E. PMID: 3834430.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    322. Effect of simulated weightlessness and chronic 1,25-dihydroxyvitamin D administration on bone metabolism. Physiologist. 1985 Dec; 28(6 Suppl):S127-8. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. PMID: 3841737.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    323. Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J Clin Endocrinol Metab. 1985 Nov; 61(5):969-75. Bikle DD, Siiteri PK, Ryzen E, Haddad JG. PMID: 3840175.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    324. Bone disease in alcohol abuse. Ann Intern Med. 1985 Jul; 103(1):42-8. Bikle DD, Genant HK, Cann C, Recker RR, Halloran BP, Strewler GJ. PMID: 2988390.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    325. Measurement of 25,26-dihydroxyvitamin D: importance of the configuration of the C-25 hydroxyl group. Biochemistry. 1984 Dec 18; 23(26):6920-5. Bikle DD, Halloran BP, Whitney JO, Hollis BW. PMID: 6543324.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    326. Differential response of duodenal epithelial cells to 1,25-dihydroxyvitamin D3 according to position on the villus: a comparison of calcium uptake, calcium-binding protein, and alkaline phosphatase activity. Endocrinology. 1984 Dec; 115(6):2077-84. Bikle DD, Zolock DT, Munson S. PMID: 6548695.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    327. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J Clin Invest. 1984 Dec; 74(6):1966-71. Bikle DD, Gee E, Halloran B, Haddad JG. PMID: 6549014; PMCID: PMC425383.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    328. Separation of isotopically labeled vitamin D metabolites by high-performance liquid chromatography. J Chromatogr. 1984 Oct 26; 303(1):229-33. Halloran BP, Bikle DD, Whitney JO. PMID: 6511833.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    329. Calmodulin may mediate 1,25-dihydroxyvitamin D-stimulated intestinal calcium transport. FEBS Lett. 1984 Aug 20; 174(1):30-3. Bikle DD, Munson S, Chafouleas J. PMID: 6547914.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    330. Effects of simulated weightlessness on bone mineral metabolism. Endocrinology. 1984 Jun; 114(6):2264-70. Globus RK, Bikle DD, Morey-Holton E. PMID: 6723581.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    331. The role of calmodulin in 1,25-dihydroxyvitamin D regulation of calcium transport across the intestinal brush border membrane. Prog Clin Biol Res. 1984; 168:193-8. Bikle DD, Munson S, Chafouleas JG. PMID: 6549067.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    332. Acute, but not chronic, metabolic acidosis disturbs 25-hydroxyvitamin D3 metabolism. Kidney Int. 1984 Jan; 25(1):47-52. Cunningham J, Bikle DD, Avioli LV. PMID: 6610073.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    333. The relationship of membrane fluidity to calcium flux in chick intestinal brush border membranes. Endocrinology. 1984 Jan; 114(1):260-7. Bikle DD, Whitney J, Munson S. PMID: 6546306.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    334. Simulating certain aspects of hypogravity: effects on bone maturation in the non-weight bearing skeleton. Aviat Space Environ Med. 1983 Dec; 54(12 Pt 1):1080-4. Simmons DJ, Grazman B, Russell JE, Walker WV, Bikle DD, Morey ER. PMID: 6661121.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    335. Calcium flux across chick duodenal brush border membrane vesicles: regulation by 1,25-dihydroxyvitamin D. Endocrinology. 1983 Dec; 113(6):2072-80. Bikle DD, Munson S, Zolock DT. PMID: 6416812.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    336. Fluoride treatment of osteoporosis: a new look at an old drug. Ann Intern Med. 1983 Jun; 98(6):1013-5. Bikle DD. PMID: 6859684.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    337. Calcium absorption and vitamin D metabolism. Clin Gastroenterol. 1983 May; 12(2):379-94. Bikle DD. PMID: 6347462.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    338. Adaptive response of humans to changes in dietary calcium: relationship between vitamin D regulated intestinal function and serum 1,25-dihydroxyvitamin D levels. Gastroenterology. 1983 Feb; 84(2):314-23. Bikle DD, Herman RH, Hull S, Hagler L, Harris D, Halloran B. PMID: 6687358.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    339. Calcium potentiates the cyclic nucleotide and phosphaturic response to parathyroid hormone infusion. J Clin Endocrinol Metab. 1983 Jan; 56(1):11-7. Bikle DD, Herman RH. PMID: 6292254.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    340. Pharmacokinetics and pharmacodynamics of 1,25-dihydroxyvitamin D3 in the chick. Endocrinology. 1982 Sep; 111(3):939-46. Bikle DD, Peck CC, Holford NH, Zolock DT, Morrissey RL. PMID: 6896685.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    341. The vitamin D endocrine system. Adv Intern Med. 1982; 27:45-71. Bikle DD. PMID: 7041549.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    342. In vitro stimulation of 25-hydroxycholecalciferol 1 alpha-hydroxylation by parathyroid hormone in chick kidney slices: evidence for a role for adenosine 3',5'-monophosphate. Endocrinology. 1981 Mar; 108(3):1002-6. Rost CR, Bikle DD, Kaplan RA. PMID: 6257493.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    343. The intestinal response to vitamin D. Rev Physiol Biochem Pharmacol. 1981; 89:63-142. Bikle DD, Morrissey RL, Zolock DT, Rasmussen H. PMID: 7015459.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    344. Action of vitamin D on intestinal calcium transport. Ann N Y Acad Sci. 1981; 372:481-501. Bikle DD, Zolock DT, Morrissey RL. PMID: 6951425.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    345. Studies of the chick renal mitochondrial 25-hydroxyvitamin D-3 24-hydroxylase. Biochim Biophys Acta. 1980 Sep 09; 615(1):208-22. Bikle DD. PMID: 6775702.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    346. Prolactin but not growth hormone stimulates 1,25-dihydroxyvitamin D3 production by chick renal preparations in vitro. Endocrinology. 1980 Jul; 107(1):81-4. Bikle DD, Spencer EM, Burke WH, Rost CR. PMID: 6892897.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    347. Calcium accumulation by chick intestinal mitochondria. Regulation by vitamin D-3 and 1,25-dihydroxyvitamin D-3. Biochim Biophys Acta. 1980 Jun 06; 598(3):561-74. Bikle DD, Askew EW, Zolock DT, Morrissey RL, Herman RH. PMID: 6155944.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    348. Effects of 1 alpha-hydroxy vitamin D3 on the rachitic chick intestine: a comparison to the effects of 1,25-dihydroxyvitamin D3. Calcif Tissue Int. 1980; 32(1):9-17. Bikle DD, Empson RN, Morrissey RL, Zolock DT, Bucci TJ, Herman RH, Pechet MM. PMID: 6775785.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    349. The mechanism of action of vitamin D in the intestine. Am J Clin Nutr. 1979 Nov; 32(11):2322-8. Bikle DD, Morrissey RL, Zolock DT. PMID: 158978.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    350. Stimulation of chick gut alkaline phosphatase activity by actinomycin D and 1,25-dihydroxyvitamin D3: evidence for independent mechanisms. J Lab Clin Med. 1979 Jul; 94(1):88-94. Bikle DD, Morrissey RL, Zolock DT, Herman RH. PMID: 313969.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    351. Work-induced muscle hypertrophy in vitamin D-deficient rats. Am J Clin Nutr. 1979 Mar; 32(3):515-6. Bikle DD, Hagler L, Lollini LO, Hull SF, Herman RH. PMID: 420144.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    352. Immunoperoxidase localization of vitamin D dependent calcium binding protein. J Histochem Cytochem. 1978 Aug; 26(8):628-34. Morrissey RL, Zolock DT, Bucci TJ, Bikle DD. PMID: 357647.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    353. A biochemical model for the ionic control of 25-hydroxyvitamin D3 1alpha-hydroxylase. J Biol Chem. 1978 May 10; 253(9):3042-8. Bikle DD, Rasmussen H. PMID: 25278.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    354. Independence of 1,25-dihydroxyvitamin D3-mediated calcium transport from de novo RNA and protein synthesis. J Biol Chem. 1978 Jan 25; 253(2):484-8. Bikle DD, Zolock DT, Morrissey RL, Herman RH. PMID: 618881.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    355. Intestinal response to 1alpha,25-dihydroxycholecalciferol. II. A timed study of the intracellular localization of calcium binding protein. Biochim Biophys Acta. 1978 Jan 03; 538(1):34-41. Morrissey RL, Empson RN, Zolock DT, Bikle DD, Bucci TJ. PMID: 620062.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    356. Intestinal response to 1 alpha, 25-dihydroxycholecalciferol. I. RNA polymerase, alkaline phosphatase, calcium and phosphorus uptake in vitro, and in vivo calcium transport and accumulation. Biochim Biophys Acta. 1978 Jan 03; 538(1):23-33. Morrissey RL, Zolock DT, Bikle DD, Empson RN, Bucci TJ. PMID: 620061.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    357. Ionic control of 1,25-dihydroxy vitamin D-3 production by isolated chick renal mitochondria. Influence of anions and sucrose. Biochim Biophys Acta. 1978 Jan 03; 538(1):127-38. Bikle DD, Rasmussen H. PMID: 413585.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    358. The effect of 1,25-dihydroxyvitamin D-3 on the distribution of alkaline phosphatase activity along the chick intestinal villus. Biochim Biophys Acta. 1977 Aug 25; 499(1):61-6. Bikle DD, Empson RN, Herman RH, Morrissey RL, Zolock DR. PMID: 889896.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    359. The ionic control of 1,25-dihydroxyvitamin D-3 synthesis in isolated chick renal mitochondria. The role of potassium. Biochim Biophys Acta. 1976 Jul 21; 437(2):394-402. Bikle DD, Murphy EW, Rasmussen H. PMID: 8103.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    360. The ionic control of 1,25-dihydroxyvitamin D3 production in isolated chick renal tubules. J Clin Invest. 1975 Feb; 55(2):292-8. Bikle DD, Rasmussen H. PMID: 236326; PMCID: PMC301747.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    361. The ionic control of 1,25-dihydroxyvitamin D3 synthesis in isolated chick renal mitochondria. The role of calcium as influenced by inorganic phosphate and hydrogen-ion. J Clin Invest. 1975 Feb; 55(2):299-304. Bikle DD, Murphy EW, Rasmussen H. PMID: 236327; PMCID: PMC301748.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    362. A comparison of the metabolism of 25-hydroxyvitamin D3 by chick renal tubules, homogenates and mitochondria. Biochim Biophys Acta. 1974 Oct 08; 362(3):439-47. Bikle DD, Rasmussen H. PMID: 4411605.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    363. The metabolism of 25-hydroxycholecalciferol by isolated renal tubules in vitro as studied by a new chromatographic technique. Biochim Biophys Acta. 1974 Oct 08; 362(3):425-38. Bikle DD, Rasmussen H. PMID: 4370485.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    364. Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. J Clin Invest. 1972 Sep; 51(9):2502-4. Rasmussen H, Wong M, Bikle D, Goodman DB. PMID: 4344734; PMCID: PMC292420.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    Daniel's Networks
    Concepts (872)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (55)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-6-g69de2244 on PROFILES-PWEB03.

    Copyright © The Regents of the University of California.