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Daniel Bikle, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSW
San Francisco CA 94143
Phone415-750-2089
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    Collapse Biography 
    Collapse Education and Training
    HarvardAB1965Harvard
    University of PennsylvaniaMD1969School of Medicine
    University of PennsylvaniaPhD1974Graduate School of Arts and Sciences

    Collapse Research 
    Collapse Research Activities and Funding
    Vitamin D and Calcium signaling in epidermal stem cell maintenance, activation, and function
    VA I01BX003814Jan 1, 2018 - Dec 31, 2021
    Role: Principal Investigator
    Mechanisms Underlying Hormonal Regulation of Fracture Repair
    VA IP1BX001599Jan 1, 2012 - Dec 31, 2015
    Role: Principal Investigator
    Role of vitamin D and calcium signaling in wound healing
    VA I01BX001066Apr 1, 2011 - Mar 31, 2015
    Role: Principal Investigator
    Role of IGF-I/integrin signaling in the periosteal response to load
    NIH/NIAMS R01AR055924Apr 1, 2008 - Jan 31, 2020
    Role: Principal Investigator
    Vitamin D Receptor Coactivators in Keratinocytes
    NIH/NIAMS R01AR050023Jul 1, 2003 - Sep 27, 2010
    Role: Principal Investigator
    IGF-1 Mediates the Anabolic Effects of PTH on Bone
    NIH/NIDDK R01DK054793Feb 15, 2001 - Jul 31, 2007
    Role: Principal Investigator
    ESTROGEN/CALCITRIOL IN THE ETIOLOGY OF BREAST CANCER
    NIH/NCI R03CA070572Sep 30, 1995 - Sep 29, 1997
    Role: Principal Investigator
    Relationship of Keratinocyte Function to Differentiation
    NIH/NIAMS P01AR039448Jul 15, 1988 - Jun 30, 1999
    Role: Principal Investigator
    VITAMIN D AND THE DIFFERENTIATION OF KERATINOCYTES
    NIH/NIAMS R01AR038386May 1, 1987 - Mar 31, 2005
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    REGULATION OF INTESTINAL CALCIUM TRANSPORT BY VITAMIN D
    NIH/NIDDK R01DK028116Apr 1, 1981 - Nov 30, 1997
    Role: Principal Investigator
    VITAMIN D STIMULATED INTESTINAL CALCIUM TRANSPORT
    NIH/NIADDK R01AM028116Apr 1, 1981 - Mar 31, 1987
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. p120-catenin suppresses proliferation and tumor growth of oral squamous cell carcinoma via inhibiting nuclear phospholipase C-?1 signaling. J Cell Physiol. 2020 Apr 30. Li L, Ji S, Shrestha C, Jiang Y, Liao L, Xu F, Liu Z, Bikle DD, Xie Z. PMID: 32356317.
      View in: PubMed   Mentions:    Fields:    
    2. Editorial: Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions. Front Endocrinol (Lausanne). 2020; 11:40. Xie Z, Wang X, Bikle DD. PMID: 32117066.
      View in: PubMed   Mentions:
    3. New aspects of vitamin D metabolism and action - addressing the skin as source and target. Nat Rev Endocrinol. 2020 04; 16(4):234-252. Bikle D, Christakos S. PMID: 32029884.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level. J Endocr Soc. 2020 Feb 01; 4(2):bvz038. Bikle DD. PMID: 32051922.
      View in: PubMed   Mentions:
    5. Vitamin D Metabolism Revised: Fall of Dogmas. J Bone Miner Res. 2019 11; 34(11):1985-1992. Bouillon R, Bikle D. PMID: 31589774.
      View in: PubMed   Mentions: 2     Fields:    
    6. Myosin 1a Regulates Osteoblast Differentiation Independent of Intestinal Calcium Transport. J Endocr Soc. 2019 Nov 01; 3(11):1993-2011. Munson S, Wang Y, Chang W, Bikle DD. PMID: 31620669.
      View in: PubMed   Mentions:
    7. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Endocr Rev. 2019 08 01; 40(4):1109-1151. Bouillon R, Marcocci C, Carmeliet G, Bikle D, White JH, Dawson-Hughes B, Lips P, Munns CF, Lazaretti-Castro M, Giustina A, Bilezikian J. PMID: 30321335.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    8. Do sunscreens block vitamin D production? A critical review by an international panel of experts. Br J Dermatol. 2019 11; 181(5):884. Bikle DD. PMID: 31259384.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. New developments in our understanding of vitamin metabolism, action and treatment. Metabolism. 2019 09; 98:112-120. Christakos S, Li S, De La Cruz J, Bikle DD. PMID: 31226354.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions. Front Endocrinol (Lausanne). 2019; 10:317. Bikle DD, Schwartz J. PMID: 31191450.
      View in: PubMed   Mentions:
    11. The Fracture Callus Is Formed by Progenitors of Different Skeletal Origins in a Site-Specific Manner. JBMR Plus. 2019 Sep; 3(9):e10193. Wang Y, Chen L, Kang M, Ling L, Tian F, Won-Kim SH, Ho S, Bikle DD. PMID: 31667451.
      View in: PubMed   Mentions:
    12. Rapid onset of hypercalcemia from high-grade lymphoma in the setting of HIV-related immune reconstitution inflammatory syndrome. Bone Rep. 2019 Jun; 10:100194. Kim SJ, Peluso MJ, Wang Y, Bikle D, Shoback D, Kim S. PMID: 30627599.
      View in: PubMed   Mentions:
    13. Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations. J Clin Endocrinol Metab. 2018 09 01; 103(9):3278-3288. Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D. PMID: 29955795.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D. Br J Clin Pharmacol. 2018 10; 84(10):2194-2207. Sempos CT, Heijboer AC, Bikle DD, Bollerslev J, Bouillon R, Brannon PM, DeLuca HF, Jones G, Munns CF, Bilezikian JP, Giustina A, Binkley N. PMID: 29851137.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    15. Vitamin D and bone and beyond. Bone Rep. 2018 Dec; 9:120-121. Bikle DD, Bouillon R. PMID: 30591929.
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    16. p120-catenin is required for regulating epidermal proliferation, differentiation, and barrier function. J Cell Physiol. 2018 01; 234(1):427-432. Xie Z, Tang Y, Man MQ, Shrestha C, Bikle DD. PMID: 29923340.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair. J Invest Dermatol. 2018 11; 138(11):2423-2431. Oda Y, Hu L, Nguyen T, Fong C, Zhang J, Guo P, Bikle DD. PMID: 29787748.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. Vitamin D Assays. Front Horm Res. 2018; 50:14-30. Bikle DD. PMID: 29597233.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review. Bone Rep. 2018 Jun; 8:255-267. Bikle DD, Patzek S, Wang Y. PMID: 29963603.
      View in: PubMed   Mentions:
    20. Current Controversies: Are Free Vitamin Metabolite Levels a More Accurate Assessment of Vitamin D Status than Total Levels? Endocrinol Metab Clin North Am. 2017 12; 46(4):901-918. Bikle DD, Malmstroem S, Schwartz J. PMID: 29080642.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. IGF-1 signaling mediated cell-specific skeletal mechano-transduction. J Orthop Res. 2018 02; 36(2):576-583. Tian F, Wang Y, Bikle DD. PMID: 28980721.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    22. Vitamin D Prevents Sunburn: Tips for the Summer? J Invest Dermatol. 2017 10; 137(10):2045-2047. Bikle DD. PMID: 28941472.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Vitamin D: Mechanisms of Action and Clinical Applications. Endocrinol Metab Clin North Am. 2017 12; 46(4):xvii-xviii. Gallagher JC, Bikle DD. PMID: 29080648.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene. J Biol Chem. 2017 08 18; 292(33):13531-13540. Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y. PMID: 28673966.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    25. Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization. Endocrinology. 2017 06 01; 158(6):1929-1938. Oda Y, Hu L, Nguyen T, Fong C, Tu CL, Bikle DD. PMID: 28368538.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    26. Current Assays to Determine Free 25-Hydroxyvitamin D in Serum. J AOAC Int. 2017 Sep 01; 100(5):1323-1327. Malmstroem S, Rejnmark L, Imboden JB, Shoback DM, Bikle DD. PMID: 28492133.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. VITAMIN D BINDING PROTEIN AND 25-HYDROXYVITAMIN D LEVELS: EMERGING CLINICAL APPLICATIONS. Endocr Pract. 2017 May; 23(5):605-613. Jassil NK, Sharma A, Bikle D, Wang X. PMID: 28095044.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Vitamin D metabolites in captivity? Should we measure free or total 25(OH)D to assess vitamin D status? J Steroid Biochem Mol Biol. 2017 10; 173:105-116. Bikle D, Bouillon R, Thadhani R, Schoenmakers I. PMID: 28093353.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    29. p120-Catenin Is Required for Dietary Calcium Suppression of Oral Carcinogenesis in Mice. J Cell Physiol. 2017 Jun; 232(6):1360-1367. Xie Z, Yuan Y, Jiang Y, Shrestha C, Chen Y, Liao L, Ji S, Deng X, Liao E, Bikle DD. PMID: 27682597.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    30. Osteogenic Differentiation of Periosteal Cells During Fracture Healing. J Cell Physiol. 2017 05; 232(5):913-921. Wang T, Zhang X, Bikle DD. PMID: 27731505.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    31. The vitamin D hypothesis: Dead or alive?: Response to Dr. William Grant's "The UVB-vitamin D3-pigment hypothesis is alive and well-AJPA-2016-00237". Am J Phys Anthropol. 2016 12; 161(4):756-757. Elias PM, Williams ML, Bikle DD. PMID: 27634223.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. Front Physiol. 2016; 7:296. Bikle DD, Jiang Y, Nguyen T, Oda Y, Tu CL. PMID: 27462278.
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    33. Extraskeletal actions of vitamin D. Ann N Y Acad Sci. 2016 07; 1376(1):29-52. Bikle DD. PMID: 27649525.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    34. Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation. Biomed Res Int. 2016; 2016:3062765. Shrestha C, Tang Y, Fan H, Li L, Zeng Q, Pennypacker SD, Bikle DD, Xie Z. PMID: 27340655.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    35. The Endocrine Society Centennial: Extrarenal Production of 1,25 Dihyroxyvitamin D Is Now Proven. Endocrinology. 2016 05; 157(5):1717-8. Bikle DD. PMID: 27014941.
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    36. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle. J Invest Dermatol. 2016 07; 136(7):1337-1345. Mady LJ, Ajibade DV, Hsaio C, Teichert A, Fong C, Wang Y, Christakos S, Bikle DD. PMID: 26994969.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    37. Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway. J Biol Chem. 2016 Apr 08; 291(15):8140-9. Tahimic CG, Long RK, Kubota T, Sun MY, Elalieh H, Fong C, Menendez AT, Wang Y, Vilardaga JP, Bikle DD. PMID: 26865633.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    38. Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites. Eur J Med Chem. 2016 Feb 15; 109:238-46. Teske KA, Bogart JW, Sanchez LM, Yu OB, Preston JV, Cook JM, Silvaggi NR, Bikle DD, Arnold LA. PMID: 26774929.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    39. Response of Vitamin D Concentration to Vitamin D3 Administration in Older Adults without Sun Exposure: A Randomized Double-Blind Trial. J Am Geriatr Soc. 2016 Jan; 64(1):65-72. Schwartz JB, Kane L, Bikle D. PMID: 26782853.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Role of IGF-I signaling in muscle bone interactions. Bone. 2015 Nov; 80:79-88. Bikle DD, Tahimic C, Chang W, Wang Y, Philippou A, Barton ER. PMID: 26453498.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    41. Antitumor Activity of 3-Indolylmethanamines 31B and PS121912. Anticancer Res. 2015 Nov; 35(11):6001-7. Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA. PMID: 26504023.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    42. Pregnane X receptor expression in skin: the good and the bad. Exp Dermatol. 2015 Nov; 24(11):829-30. Bikle DD. PMID: 26269123.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    43. Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing. J Bone Miner Res. 2015 Sep; 30(9):1572-84. Wang T, Wang Y, Menendez A, Fong C, Babey M, Tahimic CG, Cheng Z, Li A, Chang W, Bikle DD. PMID: 25801198.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    44. Vitamin D and calcium regulation of epidermal wound healing. J Steroid Biochem Mol Biol. 2016 11; 164:379-385. Oda Y, Tu CL, Menendez A, Nguyen T, Bikle DD. PMID: 26282157.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    45. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Calcif Tissue Int. 2015 Dec; 97(6):634-9. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. PMID: 26253396.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. IGF-I Signaling in Osterix-Expressing Cells Regulates Secondary Ossification Center Formation, Growth Plate Maturation, and Metaphyseal Formation During Postnatal Bone Development. J Bone Miner Res. 2015 Dec; 30(12):2239-48. Wang Y, Menendez A, Fong C, ElAlieh HZ, Kubota T, Long R, Bikle DD. PMID: 26011431.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    47. Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. J Clin Endocrinol Metab. 2015 Aug; 100(8):2832-6. Shah AD, Hsiao EC, O'Donnell B, Salmeen K, Nussbaum R, Krebs M, Baumgartner-Parzer S, Kaufmann M, Jones G, Bikle DD, Wang Y, Mathew AS, Shoback D, Block-Kurbisch I. PMID: 26097993.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Gender-Specific Differences in the Skeletal Response to Continuous PTH in Mice Lacking the IGF1 Receptor in Mature Osteoblasts. J Bone Miner Res. 2015 Jun; 30(6):1064-76. Babey M, Wang Y, Kubota T, Fong C, Menendez A, ElAlieh HZ, Bikle DD. PMID: 25502173.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    49. Selective Hyaluronan-CD44 Signaling Promotes miRNA-21 Expression and Interacts with Vitamin D Function during Cutaneous Squamous Cell Carcinomas Progression Following UV Irradiation. Front Immunol. 2015; 6:224. Bourguignon LY, Bikle D. PMID: 26029210.
      View in: PubMed   Mentions: 1     Fields:    
    50. UVB induces epidermal 11ß-hydroxysteroid dehydrogenase type 1 activity in vivo. Exp Dermatol. 2015 May; 24(5):370-6. Tiganescu A, Hupe M, Jiang YJ, Celli A, Uchida Y, Mauro TM, Bikle DD, Elias PM, Holleran WM. PMID: 25739654.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    51. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. Liver Int. 2015 Oct; 35(10):2294-300. Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB. PMID: 25757956.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    52. Highlights from the 17th workshop on vitamin D, Chicago, IL, June 17-21, 2014. J Steroid Biochem Mol Biol. 2015 Apr; 148:1-2. Welsh J, Bikle DD, Lips P. PMID: 25641118.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    53. Vitamin D receptor, a tumor suppressor in skin. Can J Physiol Pharmacol. 2015 May; 93(5):349-54. Bikle DD. PMID: 25559384.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    54. Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer. J Steroid Biochem Mol Biol. 2015 Apr; 148:47-51. Bikle DD, Oda Y, Tu CL, Jiang Y. PMID: 25445917.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    55. Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production. Evol Biol. 2014 Sep 01; 41(3):388-396. Thyssen JP, Bikle DD, Elias PM. PMID: 25506102.
      View in: PubMed   Mentions:
    56. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemother Pharmacol. 2014 Oct; 74(4):787-98. Sidhu PS, Teske K, Feleke B, Yuan NY, Guthrie ML, Fernstrum GB, Vyas ND, Han L, Preston J, Bogart JW, Silvaggi NR, Cook JM, Singh RK, Bikle DD, Arnold LA. PMID: 25107568.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    57. Ephrin B2/EphB4 mediates the actions of IGF-I signaling in regulating endochondral bone formation. J Bone Miner Res. 2014 Aug; 29(8):1900-13. Wang Y, Menendez A, Fong C, ElAlieh HZ, Chang W, Bikle DD. PMID: 24677183.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    58. Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair. PLoS One. 2014; 9(6):e99991. Yoshizaki K, Hu L, Nguyen T, Sakai K, He B, Fong C, Yamada Y, Bikle DD, Oda Y. PMID: 24949995.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    59. Calcium, Orai1, and epidermal proliferation. J Invest Dermatol. 2014 Jun; 134(6):1506-1508. Bikle DD, Mauro TM. PMID: 24825060.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    60. Highlights from the 16th Vitamin D Workshop, San Francisco, CA, June 11-14, 2013. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:1-4. Bikle D. PMID: 24793579.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    61. LncRNA: a new player in 1a, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation. Exp Dermatol. 2014 Mar; 23(3):147-50. Jiang YJ, Bikle DD. PMID: 24499465.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    62. Vitamin D-binding protein and vitamin D in blacks and whites. N Engl J Med. 2014 02 27; 370(9):879-80. Hollis BW, Bikle DD. PMID: 24571766.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    63. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Mar 20; 21(3):319-29. Bikle DD. PMID: 24529992.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    64. Development of novel Vitamin D Receptor-Coactivator Inhibitors. ACS Med Chem Lett. 2014 Feb 13; 5(2):199-204. Sidhu PS, Nassif N, McCallum MM, Teske K, Feleke B, Yuan NY, Nandhikonda P, Cook JM, Singh RK, Bikle DD, Arnold LA. PMID: 24799995.
      View in: PubMed   Mentions:
    65. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab. 2014 May; 99(5):1631-7. Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D. PMID: 24483159.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    66. Vitamin D and cancer: the promise not yet fulfilled. Endocrine. 2014 May; 46(1):29-38. Bikle DD. PMID: 24402695.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    67. IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING. Nucl Receptor Res. 2014; 1. Teske K, Nandhikonda P, Bogart JW, Feleke B, Sidhu P, Yuan N, Preston J, Goy R, Han L, Silvaggi NR, Singh RK, Bikle DD, Cook JM, Arnold LA. PMID: 25419525.
      View in: PubMed   Mentions:
    68. The vitamin D receptor: a tumor suppressor in skin. Adv Exp Med Biol. 2014; 810:282-302. Bikle DD. PMID: 25207372.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    69. LncRNA profiling reveals new mechanism for VDR protection against skin cancer formation. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:87-90. Jiang YJ, Bikle DD. PMID: 24342142.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    70. Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich, et al. Front Neuroendocrinol. 2014 Jan; 35(1):2-5. Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS. PMID: 24268499.
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    71. Variability in free 25(OH) vitamin D levels in clinical populations. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:156-8. Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D. PMID: 24240067.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    72. Reciprocal role of vitamin D receptor on ß-catenin regulated keratinocyte proliferation and differentiation. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:237-41. Hu L, Bikle DD, Oda Y. PMID: 24239508.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    73. The protective role of vitamin d signaling in non-melanoma skin cancer. Cancers (Basel). 2013 Nov 05; 5(4):1426-38. Bikle DD, Jiang Y. PMID: 24202452.
      View in: PubMed   Mentions:
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    125. Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. Mol Biol Cell. 2009 Mar; 20(6):1695-704. Xie Z, Chang SM, Pennypacker SD, Liao EY, Bikle DD. PMID: 19158393.
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    155. Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes. J Invest Dermatol. 2005 Jan; 124(1):187-97. Tu CL, Chang W, Bikle DD. PMID: 15654973.
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    156. Vitamin D and skin cancer. J Nutr. 2004 12; 134(12 Suppl):3472S-3478S. Bikle DD. PMID: 15570056.
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    157. The effect of LXR activators on AP-1 proteins in keratinocytes. J Invest Dermatol. 2004 Jul; 123(1):41-8. Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR. PMID: 15191540.
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    158. Vitamin D regulated keratinocyte differentiation. J Cell Biochem. 2004 Jun 01; 92(3):436-44. Bikle DD. PMID: 15156556.
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    159. Mice lacking 25OHD 1alpha-hydroxylase demonstrate decreased epidermal differentiation and barrier function. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):347-53. Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM. PMID: 15225799.
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    160. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):273-6. Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. PMID: 15225784.
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    161. Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):355-60. Bikle DD, Oda Y, Xie Z. PMID: 15225800.
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    162. 25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis. J Invest Dermatol. 2004 Apr; 122(4):984-92. Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM. PMID: 15102089.
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    163. The role of the calcium-sensing receptor in epidermal differentiation. Cell Calcium. 2004 Mar; 35(3):265-73. Tu CL, Oda Y, Komuves L, Bikle DD. PMID: 15200150.
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    164. Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways. J Bone Miner Res. 2004 Mar; 19(3):436-46. Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, Bikle DD. PMID: 15040832.
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    165. PTH differentially regulates expression of RANKL and OPG. J Bone Miner Res. 2004 Feb; 19(2):235-44. Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA. PMID: 14969393.
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    166. Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores. J Invest Dermatol. 2003 Oct; 121(4):688-94. Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM. PMID: 14632183.
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    167. bFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells. Calcif Tissue Int. 2003 Aug; 73(2):147-52. Nauman EA, Sakata T, Keaveny TM, Halloran BP, Bikle DD. PMID: 14565596.
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    168. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation. Mol Endocrinol. 2003 Nov; 17(11):2329-39. Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. PMID: 12893881.
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    169. Skeletal unloading induces resistance to insulin-like growth factor I on bone formation. Bone. 2003 Jun; 32(6):669-80. Sakata T, Halloran BP, Elalieh HZ, Munson SJ, Rudner L, Venton L, Ginzinger D, Rosen CJ, Bikle DD. PMID: 12810174.
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    170. The impact of skeletal unloading on bone formation. Gravit Space Biol Bull. 2003 Jun; 16(2):45-54. Bikle DD, Sakata T, Halloran BP. PMID: 12959131.
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    171. Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma. J Cell Physiol. 2003 May; 195(2):249-59. Yang LC, Ng DC, Bikle DD. PMID: 12652652.
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    172. Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate. J Cell Biochem. 2003 Mar 01; 88(4):732-43. Dolezalova H, Shankar G, Huang MC, Bikle DD, Goetzl EJ. PMID: 12577307.
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    173. Vitamin D regulated keratinocyte differentiation: role of coactivators. J Cell Biochem. 2003 Feb 01; 88(2):290-5. Bikle DD, Tu CL, Xie Z, Oda Y. PMID: 12520529.
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    174. Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why? Recent Results Cancer Res. 2003; 164:111-22. Bikle DD, Xie Z, Ng D, Tu CL, Oda Y. PMID: 12899516.
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    175. Mechanical and chemical characteristics of mineral produced by basic fibroblast growth factor-treated bone marrow stromal cells in vitro. Tissue Eng. 2002 Dec; 8(6):931-9. Nauman EA, Ebenstein DM, Hughes KF, Pruitt L, Halloran BP, Bikle DD, Keaveny TM. PMID: 12542939.
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    176. The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3. J Invest Dermatol. 2002 Nov; 119(5):1109-13. Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z. PMID: 12445200.
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    177. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. J Bone Miner Res. 2002 Sep; 17(9):1570-8. Bikle DD, Sakata T, Leary C, Elalieh H, Ginzinger D, Rosen CJ, Beamer W, Majumdar S, Halloran BP. PMID: 12211426.
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    178. Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation. J Cell Physiol. 2002 Jul; 192(1):45-54. Komuves L, Oda Y, Tu CL, Chang WH, Ho-Pao CL, Mauro T, Bikle DD. PMID: 12115735.
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    179. The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes. J Biol Chem. 2002 Oct 04; 277(40):36987-90. Xie Z, Munson SJ, Huang N, Portale AA, Miller WL, Bikle DD. PMID: 11956203.
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    180. Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol. 2002 Jan; 118(1):11-6. Xie Z, Komuves L, Yu QC, Elalieh H, Ng DC, Leary C, Chang S, Crumrine D, Yoshizawa T, Kato S, Bikle DD. PMID: 11851870.
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    181. The skeletal structure of insulin-like growth factor I-deficient mice. J Bone Miner Res. 2001 Dec; 16(12):2320-9. Bikle D, Majumdar S, Laib A, Powell-Braxton L, Rosen C, Beamer W, Nauman E, Leary C, Halloran B. PMID: 11760848.
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    182. Inhibition of 1,25-dihydroxyvitamin-D-induced keratinocyte differentiation by blocking the expression of phospholipase C-gamma1. J Invest Dermatol. 2001 Nov; 117(5):1250-4. Xie Z, Bikle DD. PMID: 11710940.
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    183. The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes. J Biol Chem. 2001 Nov 02; 276(44):41079-85. Tu CL, Chang W, Bikle DD. PMID: 11500521.
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    184. Calcium- and vitamin D-regulated keratinocyte differentiation. Mol Cell Endocrinol. 2001 May 25; 177(1-2):161-71. Bikle DD, Ng D, Tu CL, Oda Y, Xie Z. PMID: 11377831.
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    185. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. J Appl Physiol (1985). 2001 May; 90(5):1849-54. Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD. PMID: 11299276.
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    186. Selective inhibition of vitamin D hydroxylases in human keratinocytes. Steroids. 2001 Mar-May; 66(3-5):409-22. Schuster I, Egger H, Bikle D, Herzig G, Reddy GS, Stuetz A, Stuetz P, Vorisek G. PMID: 11179750.
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    187. Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D. J Lipid Res. 2001 Mar; 42(3):390-8. Hanley K, Wood L, Ng DC, He SS, Lau P, Moser A, Elias PM, Bikle DD, Williams ML, Feingold KR. PMID: 11254751.
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    188. The role of phospholipase C-gamma1 in 1alpha,25-dihydroxyvitamin D(3) regulated keratinocyte differentiation. Steroids. 2001 Mar-May; 66(3-5):339-45. Xie Z, Bikle DD. PMID: 11179742.
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    189. Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo. J Invest Dermatol. 2000 Sep; 115(3):353-60. Kömüves LG, Hanley K, Lefebvre AM, Man MQ, Ng DC, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR. PMID: 10951268.
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    190. Requirement of an AP-1 site in the calcium response region of the involucrin promoter. J Biol Chem. 2000 Aug 04; 275(31):24080-8. Ng DC, Shafaee S, Lee D, Bikle DD. PMID: 10816578.
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    191. Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. J Biol Chem. 2000 Apr 14; 275(15):11484-91. Hanley K, Kömüves LG, Ng DC, Schoonjans K, He SS, Lau P, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR. PMID: 10753967.
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    192. Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. J Invest Dermatol. 2000 Mar; 114(3):545-53. Hanley K, Ng DC, He SS, Lau P, Min K, Elias PM, Bikle DD, Mangelsdorf DJ, Williams ML, Feingold KR. PMID: 10692116.
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    193. The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation. J Biol Chem. 2000 Jan 14; 275(2):1183-90. Oda Y, Tu CL, Chang W, Crumrine D, Kömüves L, Mauro T, Elias PM, Bikle DD. PMID: 10625662.
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    194. Effects of a calcium receptor activator on the cellular response to calcium in human keratinocytes. J Invest Dermatol. 1999 Sep; 113(3):340-5. Tu CL, Oda Y, Bikle DD. PMID: 10469331.
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    195. Phospholipase C-gamma1 is required for calcium-induced keratinocyte differentiation. J Biol Chem. 1999 Jul 16; 274(29):20421-4. Xie Z, Bikle DD. PMID: 10400667.
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    196. Differences in calcium metabolism between black and white men and women. Miner Electrolyte Metab. 1999 May-Jun; 25(3):178-84. Bikle DD, Ettinger B, Sidney S, Tekawa IS, Tolan K. PMID: 10436403.
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    197. 1,25 dihydroxyvitamin D3 enhances the calcium response of keratinocytes. J Cell Physiol. 1999 Feb; 178(2):188-96. Ratnam AV, Bikle DD, Cho JK. PMID: 10048583.
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    198. Bone and hormonal changes induced by skeletal unloading in the mature male rat. Am J Physiol. 1999 Jan; 276(1 Pt 1):E62-9. Dehority W, Halloran BP, Bikle DD, Curren T, Kostenuik PJ, Wronski TJ, Shen Y, Rabkin B, Bouraoui A, Morey-Holton E. PMID: 9886951.
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    199. The response of bone to unloading. J Bone Miner Metab. 1999; 17(4):233-44. Bikle DD, Halloran BP. PMID: 10575587.
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    200. Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I. J Bone Miner Res. 1999 Jan; 14(1):21-31. Kostenuik PJ, Harris J, Halloran BP, Turner RT, Morey-Holton ER, Bikle DD. PMID: 9893062.
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    201. Six putative IQ motifs of the recombinant chicken intestinal brush border myosin I are involved in calmodulin binding. Arch Biochem Biophys. 1999 Jan 01; 361(1):94-100. Khoroshev MI, Munson SJ, Bikle DD. PMID: 9882432.
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    202. The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation. J Biol Chem. 1998 Sep 04; 273(36):23344-52. Oda Y, Tu CL, Pillai S, Bikle DD. PMID: 9722568.
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    203. Differential regulation of vitamin D responsive elements in normal and transformed keratinocytes. J Invest Dermatol. 1998 May; 110(5):730-3. Xie Z, Bikle DD. PMID: 9579536.
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    204. Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha. J Invest Dermatol. 1998 Apr; 110(4):368-75. Hanley K, Jiang Y, He SS, Friedman M, Elias PM, Bikle DD, Williams ML, Feingold KR. PMID: 9540977.
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    205. All-trans retinoic acid blocks the antiproliferative prodifferentiating actions of 1,25-dihydroxyvitamin D3 in normal human keratinocytes. J Cell Physiol. 1998 Jan; 174(1):1-8. Gibson DF, Bikle DD, Harris J. PMID: 9397150.
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    206. Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1. Mol Endocrinol. 1997 Dec; 11(13):1961-70. Fu GK, Lin D, Zhang MY, Bikle DD, Shackleton CH, Miller WL, Portale AA. PMID: 9415400.
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    207. Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells. Am J Physiol. 1997 Dec; 273(6 Pt 1):E1133-9. Kostenuik PJ, Halloran BP, Morey-Holton ER, Bikle DD. PMID: 9435529.
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    208. Biochemical markers in the assessment of bone disease. Am J Med. 1997 Nov; 103(5):427-36. Bikle DD. PMID: 9375712.
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    209. Vitamin D: a calciotropic hormone regulating calcium-induced keratinocyte differentiation. J Am Acad Dermatol. 1997 Sep; 37(3 Pt 2):S42-52. Bikle DD. PMID: 9344184.
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    210. The expression of the gap junctional protein Cx43 is restricted to proliferating and non differentiated normal and transformed keratinocytes. Exp Dermatol. 1997 Aug; 6(4):167-74. Gibson DF, Bikle DD, Harris J, Goldberg GS. PMID: 9293388.
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    211. Decrease of Ca(2+)-ATPase activity in human keratinocytes during calcium-induced differentiation. J Cell Physiol. 1997 Aug; 172(2):146-54. Cho JK, Bikle DD. PMID: 9258336.
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    212. Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading. J Bone Miner Res. 1997 Jul; 12(7):1068-74. Halloran BP, Bikle DD, Harris J, Tanner S, Curren T, Morey-Holton E. PMID: 9200006.
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    213. Spaceflight and the skeleton: lessons for the earthbound. Gravit Space Biol Bull. 1997 Jun; 10(2):119-35. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11540113.
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    214. Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element. J Biol Chem. 1997 Mar 07; 272(10):6573-7. Xie Z, Bikle DD. PMID: 9045685.
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    215. Racial differences in bone density between young adult black and white subjects persist after adjustment for anthropometric, lifestyle, and biochemical differences. J Clin Endocrinol Metab. 1997 Feb; 82(2):429-34. Ettinger B, Sidney S, Cummings SR, Libanati C, Bikle DD, Tekawa IS, Tolan K, Steiger P. PMID: 9024231.
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    216. Space flight and the skeleton: lessons for the earthbound. Endocrinologist. 1997 Jan-Feb; 7(1):10-22. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11540416.
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    218. Zipper protein, a B-G protein with the ability to regulate actin/myosin 1 interactions in the intestinal brush border. J Biol Chem. 1996 Apr 12; 271(15):9075-83. Bikle DD, Munson S, Komuves L. PMID: 8621557.
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    219. 1,25(OH)2D3-modulated calcium induced keratinocyte differentiation. J Investig Dermatol Symp Proc. 1996 Apr; 1(1):22-7. Bikle DD. PMID: 9627687.
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    220. Squamous carcinoma cell lines fail to respond to 1,25-Dihydroxyvitamin D despite normal levels of the vitamin D receptor. J Invest Dermatol. 1996 Mar; 106(3):522-5. Ratnam AV, Bikle DD, Su MJ, Pillai S. PMID: 8648187.
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    221. Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor. J Clin Invest. 1996 Feb 15; 97(4):1085-93. Bikle DD, Ratnam A, Mauro T, Harris J, Pillai S. PMID: 8613532.
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    222. Evidence for separate control mechanisms at the message, protein, and enzyme activation levels for transglutaminase during calcium-induced differentiation of normal and transformed human keratinocytes. J Invest Dermatol. 1996 Jan; 106(1):154-61. Gibson DF, Ratnam AV, Bikle DD. PMID: 8592067.
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    223. Regulation of involucrin gene expression by calcium in normal human keratinocytes. Front Biosci. 1996 Jan 01; 1:a16-24. Ng DC, Su MJ, Kim R, Bikle DD. PMID: 9159190.
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    224. 22-Oxa calcitriol is a less potent regulator of keratinocyte proliferation and differentiation due to decreased cellular uptake and enhanced catabolism. J Invest Dermatol. 1995 Nov; 105(5):693-8. Bikle DD, Abe-Hashimoto J, Su MJ, Felt S, Gibson DF, Pillai S. PMID: 7594646.
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    225. Skeletal unloading induces selective resistance to the anabolic actions of growth hormone on bone. J Bone Miner Res. 1995 Aug; 10(8):1168-76. Halloran BP, Bikle DD, Harris J, Autry CP, Currier PA, Tanner S, Patterson-Buckendahl P, Morey-Holton E. PMID: 8585419.
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    226. 1,25-Dihydroxyvitamin D3 upregulates the phosphatidylinositol signaling pathway in human keratinocytes by increasing phospholipase C levels. J Clin Invest. 1995 Jul; 96(1):602-9. Pillai S, Bikle DD, Su MJ, Ratnam A, Abe J. PMID: 7615834.
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    227. 1,25(OH)2D3-regulated human keratinocyte proliferation and differentiation: basic studies and their clinical application. J Nutr. 1995 06; 125(6 Suppl):1709S-1714S. Bikle DD. PMID: 7782932.
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    228. The molecular response of bone to growth hormone during skeletal unloading: regional differences. Endocrinology. 1995 May; 136(5):2099-109. Bikle DD, Harris J, Halloran BP, Currier PA, Tanner S, Morey-Holton E. PMID: 7720659.
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    229. Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Ann Intern Med. 1995 Apr 01; 122(7):511-3. Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP. PMID: 7872586.
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    230. Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation. Am J Physiol. 1994 Dec; 267(6 Pt 1):E822-7. Bikle DD, Harris J, Halloran BP, Morey-Holton E. PMID: 7810622.
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    231. Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage. J Bone Miner Res. 1994 Nov; 9(11):1777-87. Bikle DD, Morey-Holton ER, Doty SB, Currier PA, Tanner SJ, Halloran BP. PMID: 7863829.
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    232. Skeletal unloading induces resistance to insulin-like growth factor I. J Bone Miner Res. 1994 Nov; 9(11):1789-96. Bikle DD, Harris J, Halloran BP, Morey-Holton ER. PMID: 7532347.
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    233. Expression of the genes for insulin-like growth factors and their receptors in bone during skeletal growth. Am J Physiol. 1994 Aug; 267(2 Pt 1):E278-86. Bikle DD, Harris J, Halloran BP, Roberts CT, Leroith D, Morey-Holton E. PMID: 8074208.
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    234. Role of vitamin D, its metabolites, and analogs in the management of osteoporosis. Rheum Dis Clin North Am. 1994 Aug; 20(3):759-75. Bikle DD. PMID: 7984788.
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    235. Impact of skeletal unloading on bone formation: role of systemic and local factors. Acta Astronaut. 1994 Jul; 33:119-29. Bikle DD, Halloran BP, Morey-Holton E. PMID: 11539511.
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    236. 1,25-Dihydroxyvitamin D3 potentiates the keratinocyte response to calcium. J Biol Chem. 1994 May 20; 269(20):14723-9. Su MJ, Bikle DD, Mancianti ML, Pillai S. PMID: 7910167.
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    237. Production of 1,25 dihydroxyvitamin D3 by perfused pig skin. J Invest Dermatol. 1994 May; 102(5):796-8. Bikle DD, Halloran BP, Riviere JE. PMID: 8176265.
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    238. Regulation of calmodulin binding to the ATP extractable 110 kDa protein (myosin I) from chicken duodenal brush border by 1,25-(OH)2D3. Biochim Biophys Acta. 1994 Mar 23; 1190(2):329-36. Kaune R, Munson S, Bikle DD. PMID: 8142433.
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    239. Regulation of keratinocyte growth, differentiation, and vitamin D metabolism by analogs of 1,25-dihydroxyvitamin D. J Invest Dermatol. 1993 Nov; 101(5):713-8. Bikle DD, Gee E, Pillai S. PMID: 8228333.
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    240. Alcohol-induced bone disease: relationship to age and parathyroid hormone levels. Alcohol Clin Exp Res. 1993 Jun; 17(3):690-5. Bikle DD, Stesin A, Halloran B, Steinbach L, Recker R. PMID: 8333602.
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    241. Skeletal unloading decreases production of 1,25-dihydroxyvitamin D. Am J Physiol. 1993 May; 264(5 Pt 1):E712-6. Halloran BP, Bikle DD, Harris J, Foskett HC, Morey-Holton E. PMID: 8498493.
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    242. Elevated 1,25-dihydroxyvitamin D levels in patients with chronic obstructive pulmonary disease treated with prednisone. J Clin Endocrinol Metab. 1993 Feb; 76(2):456-61. Bikle DD, Halloran B, Fong L, Steinbach L, Shellito J. PMID: 8432789.
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    243. Vitamin D, calcium, and epidermal differentiation. Endocr Rev. 1993 Feb; 14(1):3-19. Bikle DD, Pillai S. PMID: 8491153.
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    244. Zipper protein, a newly described tropomyosin-like protein of the intestinal brush border. J Biol Chem. 1993 Jan 05; 268(1):620-6. Bikle DD, Munson S, Morrison N, Eisman J. PMID: 7678004.
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    245. Localization and quantitation of calcium pools and calcium binding sites in cultured human keratinocytes. J Cell Physiol. 1993 Jan; 154(1):101-12. Pillai S, Menon GK, Bikle DD, Elias PM. PMID: 8419397.
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    246. Alcohol-induced bone disease. World Rev Nutr Diet. 1993; 73:53-79. Bikle DD. PMID: 8367983.
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    247. Metabolic acidosis reverses the increase in serum 1,25(OH)2D in phosphorus-restricted normal men. Am J Physiol. 1992 12; 263(6):E1164-70. Portale AA, Halloran BP, Harris ST, Bikle DD, Morris RC. PMID: 1476189.
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    248. Clinical counterpoint: vitamin D: new actions, new analogs, new therapeutic potential. Endocr Rev. 1992 Nov; 13(4):765-84. Bikle DD. PMID: 1459048.
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    249. Progestin antagonism of estrogen stimulated 1,25-dihydroxyvitamin D levels. J Clin Endocrinol Metab. 1992 Aug; 75(2):519-23. Bikle DD, Halloran BP, Harris ST, Portale AA. PMID: 1639954.
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    250. Effects of dietary protein deficiency on mineral metabolism and bone mineral density. Am J Clin Nutr. 1992 Aug; 56(2):314-9. Orwoll E, Ware M, Stribrska L, Bikle D, Sanchez T, Andon M, Li H. PMID: 1636610.
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    251. Adenosine triphosphate stimulates phosphoinositide metabolism, mobilizes intracellular calcium, and inhibits terminal differentiation of human epidermal keratinocytes. J Clin Invest. 1992 Jul; 90(1):42-51. Pillai S, Bikle DD. PMID: 1321844.
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    252. Lanthanum influx into cultured human keratinocytes: effect on calcium flux and terminal differentiation. J Cell Physiol. 1992 Jun; 151(3):623-9. Pillai S, Bikle DD. PMID: 1363554.
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    253. Squamous carcinoma cell lines produce 1,25 dihydroxyvitamin D, but fail to respond to its prodifferentiating effect. J Invest Dermatol. 1991 Sep; 97(3):435-41. Bikle DD, Pillai S, Gee E. PMID: 1875043.
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    254. Tumor necrosis factor-alpha regulation of 1,25-dihydroxyvitamin D production by human keratinocytes. Endocrinology. 1991 Jul; 129(1):33-8. Bikle DD, Pillai S, Gee E, Hincenbergs M. PMID: 1675987.
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    255. Uncoupling of the calcium-sensing mechanism and differentiation in squamous carcinoma cell lines. Exp Cell Res. 1991 Feb; 192(2):567-73. Pillai S, Bikle DD, Mancianti ML, Hincenbergs M. PMID: 1988295.
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    256. Limited tissue distribution of the intestinal brush border myosin I protein. Gastroenterology. 1991 Feb; 100(2):395-402. Bikle DD, Munson S, Mancianti ML. PMID: 1985037.
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    257. Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: differences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3. J Cell Physiol. 1991 Jan; 146(1):94-100. Pillai S, Bikle DD. PMID: 1990023.
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    258. Epidermal vitamin D metabolism, function, and regulation. Adv Lipid Res. 1991; 24:321-41. Pillai S, Bikle DD. PMID: 1763717.
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    259. Different responses of trabecular and cortical bone to 1,25(OH)2D3 infusion. Am J Physiol. 1990 Nov; 259(5 Pt 1):E715-22. Bikle DD, Halloran BP, McGalliard-Cone C, Morey-Holton E. PMID: 2240210.
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    260. Calcium regulation of growth and differentiation of normal human keratinocytes: modulation of differentiation competence by stages of growth and extracellular calcium. J Cell Physiol. 1990 May; 143(2):294-302. Pillai S, Bikle DD, Mancianti ML, Cline P, Hincenbergs M. PMID: 1970572.
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    261. Serum vitamin D metabolites are not responsible for low turnover osteoporosis in chronic liver disease. J Clin Endocrinol Metab. 1989 Dec; 69(6):1234-9. Diamond T, Stiel D, Mason R, Lissner D, Bikle D, Wilson S, Posen S. PMID: 2584358.
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    262. Effects of simulated weightlessness on rat osteocalcin and bone calcium. Am J Physiol. 1989 Nov; 257(5 Pt 2):R1103-9. Patterson-Buckendahl P, Globus RK, Bikle DD, Cann CE, Morey-Holton E. PMID: 2589536.
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    263. Bone response to normal weight bearing after a period of skeletal unloading. Am J Physiol. 1989 Oct; 257(4 Pt 1):E606-10. Sessions ND, Halloran BP, Bikle DD, Wronski TJ, Cone CM, Morey-Holton E. PMID: 2801939.
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    264. Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis. J Clin Invest. 1989 May; 83(5):1527-32. Barnes PF, Modlin RL, Bikle DD, Adams JS. PMID: 2540219.
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    265. Binding and biological effects of tumor necrosis factor alpha on cultured human neonatal foreskin keratinocytes. J Clin Invest. 1989 Mar; 83(3):816-21. Pillai S, Bikle DD, Eessalu TE, Aggarwal BB, Elias PM. PMID: 2466051.
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    266. Isotopic labeling affects 1,25-dihydroxyvitamin D metabolism. Biochemistry. 1989 Feb 07; 28(3):1278-81. Halloran BP, Bikle DD, Castro ME, Gee E. PMID: 2713363.
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    267. Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes. Endocrinology. 1989 Feb; 124(2):649-54. Bikle DD, Gee E. PMID: 2463902.
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    268. Regulation of 1,25-dihydroxyvitamin D production in human keratinocytes by interferon-gamma. Endocrinology. 1989 Feb; 124(2):655-60. Bikle DD, Pillai S, Gee E, Hincenbergs M. PMID: 2463903.
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    269. Calmodulin binding to the intestinal brush-border membrane: comparison to other calcium-binding proteins. Biochim Biophys Acta. 1989 Jan 17; 1010(1):122-7. Bikle D, Munson S, Christakos S, Kumar R, Buckendahl P. PMID: 2909247.
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    270. Glucocorticoids and inhibition of bone formation induced by skeletal unloading. Am J Physiol. 1988 Dec; 255(6 Pt 1):E875-9. Halloran BP, Bikle DD, Cone CM, Morey-Holton E. PMID: 3202163.
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    271. Serum dihydrotachysterol levels and biological action in normal man. J Clin Endocrinol Metab. 1988 Jul; 67(1):198-202. Taylor A, Bikle DD, Norman ME. PMID: 3379133.
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    272. 1,25-Dihydroxyvitamin D production and receptor binding in human keratinocytes varies with differentiation. J Biol Chem. 1988 Apr 15; 263(11):5390-5. Pillai S, Bikle DD, Elias PM. PMID: 2451669.
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    273. Biochemical and morphological characterization of growth and differentiation of normal human neonatal keratinocytes in a serum-free medium. J Cell Physiol. 1988 Feb; 134(2):229-37. Pillai S, Bikle DD, Hincenbergs M, Elias PM. PMID: 2450102.
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    274. Effects of alcohol abuse on bone. Compr Ther. 1988 Feb; 14(2):16-20. Bikle DD. PMID: 3278834.
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    275. Vitamin D and epidermal differentiation: evidence for a role of endogenously produced vitamin D metabolites in keratinocyte differentiation. Skin Pharmacol. 1988; 1(3):149-60. Pillai S, Bikle DD, Elias PM. PMID: 3078531.
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    276. Vitamin D metabolite production and function in keratinocytes. Ann N Y Acad Sci. 1988; 548:27-44. Bikle DD, Pillai S. PMID: 2470300.
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    277. The effect of vitamin D status on cutaneous sterologenesis in vivo and in vitro. Biochim Biophys Acta. 1987 Sep 14; 930(2):193-200. Feingold KR, Williams ML, Pillai S, Menon GK, Halloran BP, Bikle DD, Elias PM. PMID: 3040120.
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    278. Effect of dietary acid and calcium on 25-hydroxyvitamin D metabolism by chick kidney. J Bone Miner Res. 1987 Aug; 2(4):289-96. Cunningham J, Bikle DD, Avioli LV. PMID: 3455615.
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    279. The effects of simulated weightlessness on bone maturation. Endocrinology. 1987 Feb; 120(2):678-84. Bikle DD, Halloran BP, Cone CM, Globus RK, Morey-Holton E. PMID: 3803298.
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    280. Chronic administration of 1,25-dihydroxyvitamin D3: increased bone but impaired mineralization. Endocrinology. 1986 Dec; 119(6):2580-5. Wronski TJ, Halloran BP, Bikle DD, Globus RK, Morey-Holton ER. PMID: 3780540.
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    281. Stimulation by 1,25-dihydroxyvitamin D3 of adenylate cyclase along the villus of chick duodenum. Endocrinology. 1986 Dec; 119(6):2568-73. Long RG, Bikle DD, Munson SJ. PMID: 3780539.
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    282. Effect of ethanol on intestinal calcium transport in chicks. Gastroenterology. 1986 Oct; 91(4):870-6. Bikle DD, Gee EA, Munson SJ. PMID: 3743964.
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    283. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J Clin Endocrinol Metab. 1986 Oct; 63(4):954-9. Bikle DD, Gee E, Halloran B, Kowalski MA, Ryzen E, Haddad JG. PMID: 3745408.
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    284. Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. J Clin Invest. 1986 Sep; 78(3):748-52. Bikle DD, Halloran BP, Gee E, Ryzen E, Haddad JG. PMID: 3745436.
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    285. Chronic 1,25-dihydroxyvitamin D3 administration in the rat reduces the serum concentration of 25-hydroxyvitamin D by increasing metabolic clearance rate. J Clin Invest. 1986 Sep; 78(3):622-8. Halloran BP, Bikle DD, Levens MJ, Castro ME, Globus RK, Holton E. PMID: 3489007.
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    286. 1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation. J Clin Invest. 1986 Aug; 78(2):557-66. Bikle DD, Nemanic MK, Gee E, Elias P. PMID: 2426308.
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    287. Neonatal human foreskin keratinocytes produce 1,25-dihydroxyvitamin D3. Biochemistry. 1986 Apr 08; 25(7):1545-8. Bikle DD, Nemanic MK, Whitney JO, Elias PW. PMID: 2423114.
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    288. Skeletal response to dietary calcium in a rat model simulating weightlessness. J Bone Miner Res. 1986 Apr; 1(2):191-7. Globus RK, Bikle DD, Halloran B, Morey-Holton E. PMID: 3503537.
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    289. The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading. Endocrinology. 1986 Mar; 118(3):948-54. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. PMID: 3485043.
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    290. The villus gradient of brush border membrane calmodulin and the calcium-independent calmodulin-binding protein parallels that of calcium-accumulating ability. Endocrinology. 1986 Feb; 118(2):727-32. Bikle DD, Munson S. PMID: 3753677.
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    291. The temporal response of bone to unloading. Endocrinology. 1986 Feb; 118(2):733-42. Globus RK, Bikle DD, Morey-Holton E. PMID: 3943489.
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    292. 1,25-Dihydroxyvitamin D increases calmodulin binding to specific proteins in the chick duodenal brush border membrane. J Clin Invest. 1985 Dec; 76(6):2312-6. Bikle DD, Munson S. PMID: 3841129.
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    293. Bone loss during simulated weightlessness: is it glucocorticoid mediated? Physiologist. 1985 Dec; 28(6 Suppl):S123-4. Bikle DD, Halloran BP, Cone CM, Morey-Holton E. PMID: 3834430.
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    294. Effect of simulated weightlessness and chronic 1,25-dihydroxyvitamin D administration on bone metabolism. Physiologist. 1985 Dec; 28(6 Suppl):S127-8. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. PMID: 3841737.
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    295. Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J Clin Endocrinol Metab. 1985 Nov; 61(5):969-75. Bikle DD, Siiteri PK, Ryzen E, Haddad JG. PMID: 3840175.
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    296. Bone disease in alcohol abuse. Ann Intern Med. 1985 Jul; 103(1):42-8. Bikle DD, Genant HK, Cann C, Recker RR, Halloran BP, Strewler GJ. PMID: 2988390.
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    297. Measurement of 25,26-dihydroxyvitamin D: importance of the configuration of the C-25 hydroxyl group. Biochemistry. 1984 Dec 18; 23(26):6920-5. Bikle DD, Halloran BP, Whitney JO, Hollis BW. PMID: 6543324.
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    298. Differential response of duodenal epithelial cells to 1,25-dihydroxyvitamin D3 according to position on the villus: a comparison of calcium uptake, calcium-binding protein, and alkaline phosphatase activity. Endocrinology. 1984 Dec; 115(6):2077-84. Bikle DD, Zolock DT, Munson S. PMID: 6548695.
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    299. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J Clin Invest. 1984 Dec; 74(6):1966-71. Bikle DD, Gee E, Halloran B, Haddad JG. PMID: 6549014.
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    300. Separation of isotopically labeled vitamin D metabolites by high-performance liquid chromatography. J Chromatogr. 1984 Oct 26; 303(1):229-33. Halloran BP, Bikle DD, Whitney JO. PMID: 6511833.
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    301. Calmodulin may mediate 1,25-dihydroxyvitamin D-stimulated intestinal calcium transport. FEBS Lett. 1984 Aug 20; 174(1):30-3. Bikle DD, Munson S, Chafouleas J. PMID: 6547914.
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    302. Effects of simulated weightlessness on bone mineral metabolism. Endocrinology. 1984 Jun; 114(6):2264-70. Globus RK, Bikle DD, Morey-Holton E. PMID: 6723581.
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    303. The role of calmodulin in 1,25-dihydroxyvitamin D regulation of calcium transport across the intestinal brush border membrane. Prog Clin Biol Res. 1984; 168:193-8. Bikle DD, Munson S, Chafouleas JG. PMID: 6549067.
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    304. Acute, but not chronic, metabolic acidosis disturbs 25-hydroxyvitamin D3 metabolism. Kidney Int. 1984 Jan; 25(1):47-52. Cunningham J, Bikle DD, Avioli LV. PMID: 6610073.
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    305. The relationship of membrane fluidity to calcium flux in chick intestinal brush border membranes. Endocrinology. 1984 Jan; 114(1):260-7. Bikle DD, Whitney J, Munson S. PMID: 6546306.
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    306. Simulating certain aspects of hypogravity: effects on bone maturation in the non-weight bearing skeleton. Aviat Space Environ Med. 1983 Dec; 54(12 Pt 1):1080-4. Simmons DJ, Grazman B, Russell JE, Walker WV, Bikle DD, Morey ER. PMID: 6661121.
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    307. Calcium flux across chick duodenal brush border membrane vesicles: regulation by 1,25-dihydroxyvitamin D. Endocrinology. 1983 Dec; 113(6):2072-80. Bikle DD, Munson S, Zolock DT. PMID: 6416812.
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    308. Fluoride treatment of osteoporosis: a new look at an old drug. Ann Intern Med. 1983 Jun; 98(6):1013-5. Bikle DD. PMID: 6859684.
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    309. Calcium absorption and vitamin D metabolism. Clin Gastroenterol. 1983 May; 12(2):379-94. Bikle DD. PMID: 6347462.
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    310. Adaptive response of humans to changes in dietary calcium: relationship between vitamin D regulated intestinal function and serum 1,25-dihydroxyvitamin D levels. Gastroenterology. 1983 Feb; 84(2):314-23. Bikle DD, Herman RH, Hull S, Hagler L, Harris D, Halloran B. PMID: 6687358.
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    311. Calcium potentiates the cyclic nucleotide and phosphaturic response to parathyroid hormone infusion. J Clin Endocrinol Metab. 1983 Jan; 56(1):11-7. Bikle DD, Herman RH. PMID: 6292254.
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    312. Pharmacokinetics and pharmacodynamics of 1,25-dihydroxyvitamin D3 in the chick. Endocrinology. 1982 Sep; 111(3):939-46. Bikle DD, Peck CC, Holford NH, Zolock DT, Morrissey RL. PMID: 6896685.
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    313. The vitamin D endocrine system. Adv Intern Med. 1982; 27:45-71. Bikle DD. PMID: 7041549.
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    314. In vitro stimulation of 25-hydroxycholecalciferol 1 alpha-hydroxylation by parathyroid hormone in chick kidney slices: evidence for a role for adenosine 3',5'-monophosphate. Endocrinology. 1981 Mar; 108(3):1002-6. Rost CR, Bikle DD, Kaplan RA. PMID: 6257493.
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    315. The intestinal response to vitamin D. Rev Physiol Biochem Pharmacol. 1981; 89:63-142. Bikle DD, Morrissey RL, Zolock DT, Rasmussen H. PMID: 7015459.
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    316. Action of vitamin D on intestinal calcium transport. Ann N Y Acad Sci. 1981; 372:481-501. Bikle DD, Zolock DT, Morrissey RL. PMID: 6951425.
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    317. Studies of the chick renal mitochondrial 25-hydroxyvitamin D-3 24-hydroxylase. Biochim Biophys Acta. 1980 Sep 09; 615(1):208-22. Bikle DD. PMID: 6775702.
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    318. Prolactin but not growth hormone stimulates 1,25-dihydroxyvitamin D3 production by chick renal preparations in vitro. Endocrinology. 1980 Jul; 107(1):81-4. Bikle DD, Spencer EM, Burke WH, Rost CR. PMID: 6892897.
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    319. Calcium accumulation by chick intestinal mitochondria. Regulation by vitamin D-3 and 1,25-dihydroxyvitamin D-3. Biochim Biophys Acta. 1980 Jun 06; 598(3):561-74. Bikle DD, Askew EW, Zolock DT, Morrissey RL, Herman RH. PMID: 6155944.
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    320. Effects of 1 alpha-hydroxy vitamin D3 on the rachitic chick intestine: a comparison to the effects of 1,25-dihydroxyvitamin D3. Calcif Tissue Int. 1980; 32(1):9-17. Bikle DD, Empson RN, Morrissey RL, Zolock DT, Bucci TJ, Herman RH, Pechet MM. PMID: 6775785.
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    321. The mechanism of action of vitamin D in the intestine. Am J Clin Nutr. 1979 Nov; 32(11):2322-8. Bikle DD, Morrissey RL, Zolock DT. PMID: 158978.
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    322. Stimulation of chick gut alkaline phosphatase activity by actinomycin D and 1,25-dihydroxyvitamin D3: evidence for independent mechanisms. J Lab Clin Med. 1979 Jul; 94(1):88-94. Bikle DD, Morrissey RL, Zolock DT, Herman RH. PMID: 313969.
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    323. Work-induced muscle hypertrophy in vitamin D-deficient rats. Am J Clin Nutr. 1979 Mar; 32(3):515-6. Bikle DD, Hagler L, Lollini LO, Hull SF, Herman RH. PMID: 420144.
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    324. Immunoperoxidase localization of vitamin D dependent calcium binding protein. J Histochem Cytochem. 1978 Aug; 26(8):628-34. Morrissey RL, Zolock DT, Bucci TJ, Bikle DD. PMID: 357647.
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    325. Independence of 1,25-dihydroxyvitamin D3-mediated calcium transport from de novo RNA and protein synthesis. J Biol Chem. 1978 Jan 25; 253(2):484-8. Bikle DD, Zolock DT, Morrissey RL, Herman RH. PMID: 618881.
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    326. Ionic control of 1,25-dihydroxy vitamin D-3 production by isolated chick renal mitochondria. Influence of anions and sucrose. Biochim Biophys Acta. 1978 Jan 03; 538(1):127-38. Bikle DD, Rasmussen H. PMID: 413585.
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    327. Intestinal response to 1alpha,25-dihydroxycholecalciferol. II. A timed study of the intracellular localization of calcium binding protein. Biochim Biophys Acta. 1978 Jan 03; 538(1):34-41. Morrissey RL, Empson RN, Zolock DT, Bikle DD, Bucci TJ. PMID: 620062.
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    328. Intestinal response to 1 alpha, 25-dihydroxycholecalciferol. I. RNA polymerase, alkaline phosphatase, calcium and phosphorus uptake in vitro, and in vivo calcium transport and accumulation. Biochim Biophys Acta. 1978 Jan 03; 538(1):23-33. Morrissey RL, Zolock DT, Bikle DD, Empson RN, Bucci TJ. PMID: 620061.
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    329. The effect of 1,25-dihydroxyvitamin D-3 on the distribution of alkaline phosphatase activity along the chick intestinal villus. Biochim Biophys Acta. 1977 Aug 25; 499(1):61-6. Bikle DD, Empson RN, Herman RH, Morrissey RL, Zolock DR. PMID: 889896.
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    330. The ionic control of 1,25-dihydroxyvitamin D3 synthesis in isolated chick renal mitochondria. The role of calcium as influenced by inorganic phosphate and hydrogen-ion. J Clin Invest. 1975 Feb; 55(2):299-304. Bikle DD, Murphy EW, Rasmussen H. PMID: 236327.
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    331. The ionic control of 1,25-dihydroxyvitamin D3 production in isolated chick renal tubules. J Clin Invest. 1975 Feb; 55(2):292-8. Bikle DD, Rasmussen H. PMID: 236326.
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    332. A comparison of the metabolism of 25-hydroxyvitamin D3 by chick renal tubules, homogenates and mitochondria. Biochim Biophys Acta. 1974 Oct 08; 362(3):439-47. Bikle DD, Rasmussen H. PMID: 4411605.
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    333. The metabolism of 25-hydroxycholecalciferol by isolated renal tubules in vitro as studied by a new chromatographic technique. Biochim Biophys Acta. 1974 Oct 08; 362(3):425-38. Bikle DD, Rasmussen H. PMID: 4370485.
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    334. Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. J Clin Invest. 1972 Sep; 51(9):2502-4. Rasmussen H, Wong M, Bikle D, Goodman DB. PMID: 4344734.
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