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Daniel Coutandin, PhD

Title(s)Postdoctoral Scholar, Biochemistry and Biophysics
SchoolSchool of Medicine
Phone415-476-5143
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    Collapse Biography 
    Collapse Education and Training
    Goethe University, Frankfurt, GermanyDr. phil. nat.10/2014Biochemistry
    Goethe University, Frankfurt, GermanyDiploma09/2009Biochemistry
    Collapse Awards and Honors
    University of California San Francisco2017  - 2019HFSP Postdoctoral Fellowship
    Goethe University (Frankfurt, Germany)2014PhD in Biochemistry ("summa cum laude")
    Goethe University (Frankfurt, Germany)2010  - 2012BIF PhD Fellowship
    Goethe University (Frankfurt, Germany)2009"Procter&Gamble Diplom-Förderpreis" for best diploma work in Biochemistry

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V. Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63. Nat Struct Mol Biol. 2018 Mar; 25(3):261-269. PMID: 29483652.
      View in: PubMed
    2. Gebel J, Tuppi M, Krauskopf K, Coutandin D, Pitzius S, Kehrloesser S, Osterburg C, Dötsch V. Control mechanisms in germ cells mediated by p53 family proteins. J Cell Sci. 2017 Aug 09. PMID: 28794013.
      View in: PubMed
    3. Gebel J, Luh LM, Coutandin D, Osterburg C, Löhr F, Schäfer B, Frombach AS, Sumyk M, Buchner L, Krojer T, Salah E, Mathea S, Güntert P, Knapp S, Dötsch V. Mechanism of TAp73 inhibition by ?Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ. 2016 12; 23(12):1930-1940. PMID: 27716744.
      View in: PubMed
    4. Coutandin D, Osterburg C, Srivastav RK, Sumyk M, Kehrloesser S, Gebel J, Tuppi M, Hannewald J, Schäfer B, Salah E, Mathea S, Müller-Kuller U, Doutch J, Grez M, Knapp S, Dötsch V. Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level. Elife. 2016 03 14; 5. PMID: 27021569.
      View in: PubMed
    5. Luh LM, Kehrloesser S, Deutsch GB, Gebel J, Coutandin D, Schäfer B, Agostini M, Melino G, Dötsch V. Analysis of the oligomeric state and transactivation potential of TAp73a. Cell Death Differ. 2013 Aug; 20(8):1008-16. PMID: 23538419; PMCID: PMC3705593.
    6. Deutsch GB, Zielonka EM, Coutandin D, Dötsch V. Quality control in oocytes: domain-domain interactions regulate the activity of p63. Cell Cycle. 2011 Jun 15; 10(12):1884-5. PMID: 21555912.
      View in: PubMed
    7. Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V. DNA damage in oocytes induces a switch of the quality control factor TAp63a from dimer to tetramer. Cell. 2011 Feb 18; 144(4):566-76. PMID: 21335238; PMCID: PMC3087504.
    8. Coutandin D, Ou HD, Löhr F, Dötsch V. Tracing the protectors path from the germ line to the genome. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15318-25. PMID: 20696896; PMCID: PMC2932610.
    9. Dötsch V, Bernassola F, Coutandin D, Candi E, Melino G. p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol. 2010 Sep; 2(9):a004887. PMID: 20484388; PMCID: PMC2926756.
    10. Coutandin D, Löhr F, Niesen FH, Ikeya T, Weber TA, Schäfer B, Zielonka EM, Bullock AN, Yang A, Güntert P, Knapp S, McKeon F, Ou HD, Dötsch V. Conformational stability and activity of p73 require a second helix in the tetramerization domain. Cell Death Differ. 2009 Dec; 16(12):1582-9. PMID: 19763140.
      View in: PubMed