David Agard, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St, #S412D
San Francisco CA 94158
Phone415-476-5143
Pronounshe/him/his
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    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division - Biochemistry

    Collapse Research 
    Collapse Research Activities and Funding
    Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases
    NIH U54NS123985Sep 27, 2021 - Aug 31, 2026
    Role: Co-Principal Investigator
    Structure and Mechanism: Hsp90 proteostasis, cilia biogenesis and the jumbo phage ?nucleus?
    NIH R35GM118099Jun 1, 2016 - May 31, 2026
    Role: Principal Investigator
    The Yeast Centrosome - Structure Assembly & Function
    NIH P01GM105537Sep 1, 2014 - Aug 31, 2020
    Role: Co-Investigator
    Characterization of a bacteriophage tubulin involved in viral replication
    NIH R01GM104556Aug 1, 2013 - Apr 30, 2018
    Role: Principal Investigator
    Structural Basis of Protein Homeostasis
    NIH U01GM098254Sep 30, 2012 - Jul 31, 2016
    Role: Principal Investigator
    National Resource for Automated Molecular Microscopy
    NIH P41RR017573Sep 30, 2002 - Jul 31, 2012
    Role: Co-Investigator
    STRUCTURE AND DYNAMICS OF NUCLEAR RECEPTORS
    NIH P01DK058390Aug 15, 2000 - Jul 31, 2006
    Role: Co-Investigator
    FASEB CONFERENCE: PROTEIN FOLDING AND ASSEMBLY IN CELLS
    NIH R13GM061717Jul 1, 2000 - Jun 30, 2001
    Role: Principal Investigator
    GATAN IMAGING ENERGY FILTER WITH CCD CAMERA FOR IVEM
    NIH S10RR013926Feb 1, 2000 - Jan 31, 2001
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    BioCAT - Biophysics Collaborative Access Team
    NIH P41RR008630Sep 30, 1995 - Mar 31, 2012
    Role: Co-Investigator
    Molecular Biophysics Training Grant
    NIH T32GM008284Sep 30, 1988 - Jun 30, 2023
    Role: Principal Investigator
    National Biomedical NMR Resource at Madison
    NIH P41RR002301Jul 1, 1985 - Feb 28, 2015
    Role: Co-Investigator
    Macromolecular Diffraction Resource: MacCHESS
    NIH P41RR001646Sep 1, 1983 - Jun 30, 2013
    Role: Co-Investigator
    Centrosome structure and mechanism of MT nucleation by gamma-tubulin complexes
    NIH R01GM031627Mar 1, 1983 - Dec 31, 2016
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    A Synchroton Radiation Structural Biology Resource
    NIH P41RR001209Mar 1, 1980 - Feb 28, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun. 2024 Mar 12; 15(1):2225. Chio US, Palovcak E, Smith AAA, Autzen H, Muñoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y. PMID: 38472177; PMCID: PMC10933330.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Poc1 is a basal body inner junction protein that promotes triplet microtubule integrity and interconnections. bioRxiv. 2023 Nov 28. Ruehle MD, Li S, Agard DA, Pearson CG. PMID: 38014135; PMCID: PMC10680851.
      View in: PubMed   Mentions:
    3. Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat Struct Mol Biol. 2023 Dec; 30(12):1867-1877. Noddings CM, Johnson JL, Agard DA. PMID: 37945740; PMCID: PMC10716051.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. The next decade in structural biology. Structure. 2023 11 02; 31(11):1284-1288. Walsh MA, Nannenga BL, Gonen T, Sexton PM, Wootten D, Chiu W, Sun F, Carragher B, Potter CS, Agard D, Burley SK. PMID: 37922863.
      View in: PubMed   Mentions:    Fields:    
    5. De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 11 09; 186(23):5041-5053.e19. Chen Z, Shiozaki M, Haas KM, Skinner WM, Zhao S, Guo C, Polacco BJ, Yu Z, Krogan NJ, Lishko PV, Kaake RM, Vale RD, Agard DA. PMID: 37865089; PMCID: PMC10842264.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    6. Next-generation proteomics for quantitative Jumbophage-bacteria interaction mapping. Nat Commun. 2023 08 24; 14(1):5156. Fossati A, Mozumdar D, Kokontis C, Mèndez-Moran M, Nieweglowska E, Pelin A, Li Y, Guo B, Krogan NJ, Agard DA, Bondy-Denomy J, Swaney DL. PMID: 37620325; PMCID: PMC10449902.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    7. Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. bioRxiv. 2023 Jun 20. Chio US, Palovcak E, Autzen AAA, Autzen HE, Muñoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y. PMID: 37546986; PMCID: PMC10402172.
      View in: PubMed   Mentions:
    8. Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun. 2023 04 17; 14(1):2197. Jaime-Garza M, Nowotny CA, Coutandin D, Wang F, Tabios M, Agard DA. PMID: 37069154; PMCID: PMC10110553.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Next-generation interaction proteomics for quantitative Jumbophage-bacteria interaction mapping. bioRxiv. 2023 Feb 23. Fossati A, Mozumdar D, Kokontis C, Mèndez-Moran M, Nieweglowska E, Pelin A, Li Y, Guo B, Krogan NJ, Agard DA, Bondy-Denomy J, Swaney DL. PMID: 36711836; PMCID: PMC9882154.
      View in: PubMed   Mentions:
    10. The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun. 2023 02 18; 14(1):927. Nieweglowska ES, Brilot AF, Méndez-Moran M, Kokontis C, Baek M, Li J, Cheng Y, Baker D, Bondy-Denomy J, Agard DA. PMID: 36807264; PMCID: PMC9938867.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    11. Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the Glucocorticoid Receptor. bioRxiv. 2023 Jan 16. Noddings CM, Johnson JL, Agard DA. PMID: 36711821; PMCID: PMC9882067.
      View in: PubMed   Mentions:
    12. Improved Analysis of Cross-Linking Mass Spectrometry Data with Kojak 2.0, Advanced by Integration into the Trans-Proteomic Pipeline. J Proteome Res. 2023 02 03; 22(2):647-655. Hoopmann MR, Shteynberg DD, Zelter A, Riffle M, Lyon AS, Agard DA, Luan Q, Nolen BJ, MacCoss MJ, Davis TN, Moritz RL. PMID: 36629399; PMCID: PMC10234491.
      View in: PubMed   Mentions:    Fields:    
    13. In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes. Nat Struct Mol Biol. 2023 03; 30(3):360-369. Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Yu Z, Lishko PV, Agard DA, Vale RD. PMID: 36593309; PMCID: PMC10023559.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    14. Solution of the protein structure prediction problem at last: crucial innovations and next frontiers. Fac Rev. 2022; 11:38. Agard DA, Bowman GR, DeGrado W, Dokholyan NV, Zhou HX. PMID: 36644294; PMCID: PMC9815721.
      View in: PubMed   Mentions:
    15. Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. J Biol Chem. 2022 09; 298(9):102288. Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D. PMID: 35926713; PMCID: PMC9440446.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. AreTomo: An integrated software package for automated marker-free, motion-corrected cryo-electron tomographic alignment and reconstruction. J Struct Biol X. 2022; 6:100068. Zheng S, Wolff G, Greenan G, Chen Z, Faas FGA, Bárcena M, Koster AJ, Cheng Y, Agard DA. PMID: 35601683; PMCID: PMC9117686.
      View in: PubMed   Mentions: 36  
    17. Author Correction: Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface. Nature. 2022 Feb; 602(7898):E26. Diwanji D, Trenker R, Thaker TM, Wang F, Agard DA, Verba KA, Jura N. PMID: 35132240.
      View in: PubMed   Mentions:    Fields:    
    18. Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila. Life Sci Alliance. 2022 03; 5(3). Li S, Fernandez JJ, Fabritius AS, Agard DA, Winey M. PMID: 34969817; PMCID: PMC8742875.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature. 2022 01; 601(7893):460-464. Wang RY, Noddings CM, Kirschke E, Myasnikov AG, Johnson JL, Agard DA. PMID: 34937942; PMCID: PMC9179170.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    20. Structure of Hsp90-p23-GR reveals the Hsp90 client-remodelling mechanism. Nature. 2022 01; 601(7893):465-469. Noddings CM, Wang RY, Johnson JL, Agard DA. PMID: 34937936; PMCID: PMC8994517.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    21. Entropy-regularized deconvolution of cellular cryotransmission electron tomograms. Proc Natl Acad Sci U S A. 2021 12 14; 118(50). Croxford M, Elbaum M, Arigovindan M, Kam Z, Agard D, Villa E, Sedat J. PMID: 34876518; PMCID: PMC8685678.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    22. Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface. Nature. 2021 12; 600(7888):339-343. Diwanji D, Trenker R, Thaker TM, Wang F, Agard DA, Verba KA, Jura N. PMID: 34759323; PMCID: PMC9298180.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    23. Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs. Mol Biol Cell. 2021 11 01; 32(21):br8. Fabritius AS, Bayless BA, Li S, Stoddard D, Heydeck W, Ebmeier CC, Anderson L, Gunnels T, Nachiappan C, Whittall JB, Old W, Agard DA, Nicastro D, Winey M. PMID: 34406789; PMCID: PMC8693976.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    24. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Res Sq. 2021 May 19. Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. PMID: 34031651; PMCID: PMC8142659.
      View in: PubMed   Mentions: 1  
    25. Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM. J Struct Biol. 2021 09; 213(3):107745. Sun M, Azumaya CM, Tse E, Bulkley DP, Harrington MB, Gilbert G, Frost A, Southworth D, Verba KA, Cheng Y, Agard DA. PMID: 33984504.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    26. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv. 2021 May 11. Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. PMID: 34013269; PMCID: PMC8132225.
      View in: PubMed   Mentions: 3  
    27. CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation. Elife. 2021 05 05; 10. Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA. PMID: 33949948; PMCID: PMC8099430.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    28. Microtubules form by progressively faster tubulin accretion, not by nucleation-elongation. J Cell Biol. 2021 05 03; 220(5). Rice LM, Moritz M, Agard DA. PMID: 33734292; PMCID: PMC7980253.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    29. Hsp70 chaperone blocks α-synuclein oligomer formation via a novel engagement mechanism. J Biol Chem. 2021 Jan-Jun; 296:100613. Tao J, Berthet A, Citron YR, Tsiolaki PL, Stanley R, Gestwicki JE, Agard DA, McConlogue L. PMID: 33798554; PMCID: PMC8102405.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    30. [The basics of immobilisation]. Rev Infirm. 2021 Jan; 70(267):28-30. Rebours I, Agard D, Messager C, Cattelin C, Barbier O, Choufani C. PMID: 33455677.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science. 2020 12 04; 370(6521). Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, et al. PMID: 33060197; PMCID: PMC7808408.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansCells
    32. General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM. Proc Natl Acad Sci U S A. 2020 09 29; 117(39):24269-24273. Wang F, Liu Y, Yu Z, Li S, Feng S, Cheng Y, Agard DA. PMID: 32913054; PMCID: PMC7533693.
      View in: PubMed   Mentions: 30     Fields:    
    33. A molecular pore spans the double membrane of the coronavirus replication organelle. Science. 2020 09 11; 369(6509):1395-1398. Wolff G, Limpens RWAL, Zevenhoven-Dobbe JC, Laugks U, Zheng S, de Jong AWM, Koning RI, Agard DA, Grünewald K, Koster AJ, Snijder EJ, Bárcena M. PMID: 32763915; PMCID: PMC7665310.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    34. XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions. Mol Biol Cell. 2020 09 15; 31(20):2187-2194. King BR, Moritz M, Kim H, Agard DA, Asbury CL, Davis TN. PMID: 32726183; PMCID: PMC7550701.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    35. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859; PMCID: PMC7431030.
      View in: PubMed   Mentions: 2284     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    36. Author Correction: Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome. Nat Commun. 2020 Apr 15; 11(1):1862. Gopalakrishnan J, Mennella V, Blachon S, Zhai B, Smith AH, Megraw TL, Nicastro D, Gygi SP, Agard DA, Avidor-Reiss T. PMID: 32296038; PMCID: PMC7160143.
      View in: PubMed   Mentions: 1     Fields:    
    37. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329; PMCID: PMC7239059.
      View in: PubMed   Mentions: 28  
    38. The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis. BMC Biol. 2020 01 27; 18(1):10. Joshi A, Dai L, Liu Y, Lee J, Ghahhari NM, Segala G, Beebe K, Jenkins LM, Lyons GC, Bernasconi L, Tsai FTF, Agard DA, Neckers L, Picard D. PMID: 31987035; PMCID: PMC6986101.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    39. Electron cryotomography of intact motile cilia defines the basal body to axoneme transition. J Cell Biol. 2020 01 06; 219(1). Greenan GA, Vale RD, Agard DA. PMID: 31874113; PMCID: PMC7039205.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    40. Amino and PEG-amino graphene oxide grids enrich and protect samples for high-resolution single particle cryo-electron microscopy. J Struct Biol. 2020 02 01; 209(2):107437. Wang F, Yu Z, Betegon M, Campbell MG, Aksel T, Zhao J, Li S, Douglas SM, Cheng Y, Agard DA. PMID: 31866389; PMCID: PMC7272056.
      View in: PubMed   Mentions: 24     Fields:    
    41. A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases. Nature. 2020 01; 577(7789):244-248. Mendoza SD, Nieweglowska ES, Govindarajan S, Leon LM, Berry JD, Tiwari A, Chaikeeratisak V, Pogliano J, Agard DA, Bondy-Denomy J. PMID: 31819262; PMCID: PMC6949375.
      View in: PubMed   Mentions: 75     Fields:    Translation:Cells
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    282. Spatial organization of the Drosophila nucleus: a three-dimensional cytogenetic study. J Cell Sci Suppl. 1984; 1:223-34. Gruenbaum Y, Hochstrasser M, Mathog D, Saumweber H, Agard DA, Sedat JW. PMID: 6442295.
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    283. A least-squares method for determining structure factors in three-dimensional tilted-view reconstructions. J Mol Biol. 1983 Jul 15; 167(4):849-52. Agard DA. PMID: 6876167.
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    284. Three-dimensional architecture of a polytene nucleus. Nature. 1983 Apr 21; 302(5910):676-81. Agard DA, Sedat JW. PMID: 6403872.
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    285. [Syndrome of inappropriate antidiuretic hormone secretion. A report of two cases with hyponatremia and hypouricemia]. Sem Hop. 1982 Sep 23; 58(34):1925-7. Malbran J, Agard D, Libeskind M, Redelsperger PY, Lecouillard C, Pannetier C. PMID: 6293074.
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    286. Linking regions between helices in bacteriorhodopsin revealed. Biophys J. 1982 Mar; 37(3):589-602. Agard DA, Stroud RM. PMID: 7074187; PMCID: PMC1328844.
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    287. Studies on the phosphorylation and synthesis of type I regulatory subunit of cyclic AMP-dependent protein kinase in intact S49 mouse lymphoma cells. J Biol Chem. 1981 Nov 10; 256(21):11356-64. Steinberg RA, Agard DA. PMID: 6270151.
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    288. Turnover of regulatory subunit of cyclic AMP-dependent protein kinase in S49 mouse lymphoma cells. Regulation by catalytic subunit and analogs of cyclic AMP. J Biol Chem. 1981 Nov 10; 256(21):10731-4. Steinberg RA, Agard DA. PMID: 6270127.
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    289. Quantitative analysis of electrophoretograms: a mathematical approach to super-resolution. Anal Biochem. 1981 Mar 01; 111(2):257-68. Agard DA, Steinberg RA, Stroud RM. PMID: 7247021.
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    290. [Hemorrhoids. Physiopathogenic concepts and approach to a rational treatment]. Gastroenterol Clin Biol. 1979 Oct; 3(10):705-8. Libeskind M, Lugagne F, Malbran J, Agard D, Redelsperger PY. PMID: 527779.
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    291. Structure determination of asymmetric membrane profiles using an iterative Fourier method. Biophys J. 1979 Mar; 25(3):495-512. Stroud RM, Agard DA. PMID: 318062; PMCID: PMC1328487.
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    292. [Gastrointestinal haemorrhage in the cirrhotic. The value of injectable posterior pituitary extract (author's transl)]. Nouv Presse Med. 1978 May 06; 7(18):1537-40. Libeskind M, Malbran J, Lugagne F, Redelsperger PY, Bourgeois J, Agard D. PMID: 307734.
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    293. [The excision of villous tumours of the rectum via a trans-sphincterian anal approach (author's transl)]. Nouv Presse Med. 1978 Mar 18; 7(11):935-6. Libeskind M, Lugagne F, Malbran J, Agard D, Redelsperger PY. PMID: 643560.
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    294. [Secondary melanomas of the liver. Appropos of 3 cases with hepatic symptomatology]. Med Chir Dig. 1978; 7(4):315-8. Libeskind M, Redelsperger PY, Lugagne F, Malbran J, Agard D. PMID: 672278.
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    295. Structural studies of a membrane-bound acetylcholine receptor from Torpedo californica. J Mol Biol. 1977 Nov; 116(4):635-59. Ross MJ, Klymkowsky MW, Agard DA, Stroud RM. PMID: 563472.
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    296. [Systemic amyloidosis and multiple myeloma. Report of a case with the association of light chain myeloma and gastric plasmacytosis (author's transl)]. Gastroenterol Clin Biol. 1977 Mar; 1(3):267-74. Libeskind M, Malbran J, Lugagne F, Agard D, Gatineau-Saillant C, Guyet-Rousset P. PMID: 408215.
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