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Dave Kokel, PhD

Title(s)Assistant Professor, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-7609
ORCID ORCID Icon0000-0002-1981-1511 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies. J Med Chem. 2020 02 13; 63(3):1142-1155. Dunlap LE, Azinfar A, Ly C, Cameron LP, Viswanathan J, Tombari RJ, Myers-Turnbull D, Taylor JC, Grodzki AC, Lein PJ, Kokel D, Olson DE. PMID: 31977208.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation. Nat Commun. 2019 09 09; 10(1):4078. McCarroll MN, Gendelev L, Kinser R, Taylor J, Bruni G, Myers-Turnbull D, Helsell C, Carbajal A, Rinaldi C, Kang HJ, Gong JH, Sello JK, Tomita S, Peterson RT, Keiser MJ, Kokel D. PMID: 31501447.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    3. s1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016 07; 12(7):552-8. Rennekamp AJ, Huang XP, Wang Y, Patel S, Lorello PJ, Cade L, Gonzales AP, Yeh JR, Caldarone BJ, Roth BL, Kokel D, Peterson RT. PMID: 27239788.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    4. Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds. Nat Chem Biol. 2016 07; 12(7):559-66. Bruni G, Rennekamp AJ, Velenich A, McCarroll M, Gendelev L, Fertsch E, Taylor J, Lakhani P, Lensen D, Evron T, Lorello PJ, Huang XP, Kolczewski S, Carey G, Caldarone BJ, Prinssen E, Roth BL, Keiser MJ, Peterson RT, Kokel D. PMID: 27239787.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    5. Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology. ACS Chem Biol. 2016 Apr 15; 11(4):842-9. McCarroll MN, Gendelev L, Keiser MJ, Kokel D. PMID: 26845413.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    6. Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish. Front Pharmacol. 2014; 5:153. Bruni G, Lakhani P, Kokel D. PMID: 25104936.
      View in: PubMed   Mentions:
    7. Identification of nonvisual photomotor response cells in the vertebrate hindbrain. J Neurosci. 2013 Feb 27; 33(9):3834-43. Kokel D, Dunn TW, Ahrens MB, Alshut R, Cheung CY, Saint-Amant L, Bruni G, Mateus R, van Ham TJ, Shiraki T, Fukada Y, Kojima D, Yeh JR, Mikut R, von Lintig J, Engert F, Peterson RT. PMID: 23447595.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    8. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr; 9(4):257-63. Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. PMID: 23396078.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    9. An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action. J Biomol Screen. 2013 Jan; 18(1):108-15. Jin S, Sarkar KS, Jin YN, Liu Y, Kokel D, Van Ham TJ, Roberts LD, Gerszten RE, Macrae CA, Peterson RT. PMID: 22960781.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    10. Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology. Trends Biotechnol. 2012 Aug; 30(8):421-5. Kokel D, Rennekamp AJ, Shah AH, Liebel U, Peterson RT. PMID: 22652049.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    11. Apoptotic cells are cleared by directional migration and elmo1- dependent macrophage engulfment. Curr Biol. 2012 May 08; 22(9):830-6. van Ham TJ, Kokel D, Peterson RT. PMID: 22503503.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    12. Chemical informatics and target identification in a zebrafish phenotypic screen. Nat Chem Biol. 2011 Dec 18; 8(2):144-6. Laggner C, Kokel D, Setola V, Tolia A, Lin H, Irwin JJ, Keiser MJ, Cheung CY, Minor DL, Roth BL, Peterson RT, Shoichet BK. PMID: 22179068.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    13. Using the zebrafish photomotor response for psychotropic drug screening. Methods Cell Biol. 2011; 105:517-24. Kokel D, Peterson RT. PMID: 21951545.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    14. cables1 is required for embryonic neural development: molecular, cellular, and behavioral evidence from the zebrafish. Mol Reprod Dev. 2011 Jan; 78(1):22-32. Groeneweg JW, White YA, Kokel D, Peterson RT, Zukerberg LR, Berin I, Rueda BR, Wood AW. PMID: 21268180.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    15. Live imaging of apoptotic cells in zebrafish. FASEB J. 2010 Nov; 24(11):4336-42. van Ham TJ, Mapes J, Kokel D, Peterson RT. PMID: 20601526.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    16. Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nat Chem Biol. 2010 Mar; 6(3):231-237. Kokel D, Bryan J, Laggner C, White R, Cheung CY, Mateus R, Healey D, Kim S, Werdich AA, Haggarty SJ, Macrae CA, Shoichet B, Peterson RT. PMID: 20081854.
      View in: PubMed   Mentions: 164     Fields:    
    17. Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science. 2010 Jan 15; 327(5963):348-51. Rihel J, Prober DA, Arvanites A, Lam K, Zimmerman S, Jang S, Haggarty SJ, Kokel D, Rubin LL, Peterson RT, Schier AF. PMID: 20075256.
      View in: PubMed   Mentions: 205     Fields:    Translation:AnimalsCells
    18. Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish. Brief Funct Genomic Proteomic. 2008 Nov; 7(6):483-90. Kokel D, Peterson RT. PMID: 18784194.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    19. Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9. Mol Cell. 2008 Aug 22; 31(4):586-97. Breckenridge DG, Kang BH, Kokel D, Mitani S, Staehelin LA, Xue D. PMID: 18722182.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    20. A class of benzenoid chemicals suppresses apoptosis in C. elegans. Chembiochem. 2006 Dec; 7(12):2010-5. Kokel D, Xue D. PMID: 17051661.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    21. The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans. Nat Chem Biol. 2006 Jun; 2(6):338-45. Kokel D, Li Y, Qin J, Xue D. PMID: 16699520.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    22. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature. 2005 Oct 06; 437(7060):831-7. Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y. PMID: 16208361.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    23. Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4. Mol Cell. 2004 Sep 24; 15(6):999-1006. Yan N, Gu L, Kokel D, Chai J, Li W, Han A, Chen L, Xue D, Shi Y. PMID: 15383288.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
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