David Castillo Azofeifa, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentOrofacial Sciences
Address513 Parnassus Ave
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    Universidad de Costa RicaB.S.2006Biology
    University of South CarolinaPSM2010Biological Sciences
    University of Colorado Anschutz Medical CampusPh.D.2016Cell and Developmental Biology

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    Collapse Overview
    The scientific area to which I have devoted most of my work is stem cell research. I am interested in signaling circuits that might regulate the stem/progenitor cell pool(s) within epithelial tissues, which are responsible for homeostatic maintenance and regeneration after injury. Uncovering key signals for stem cell proliferation and differentiation will provide new insights useful for disease treatments and regenerative medicine.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chukwurah E, Willingham V, Singh M, Castillo-Azofeifa D, Patel RC. Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT. J Cell Biochem. 2018 Apr; 119(4):3598-3607. PMID: 29231267.
      View in: PubMed
    2. Castillo-Azofeifa D, Losacco JT, Salcedo E, Golden EJ, Finger TE, Barlow LA. Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance. Development. 2017 09 01; 144(17):3054-3065. PMID: 28743797.
      View in: PubMed
    3. Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, Barlow LA. Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development. 2014 Aug; 141(15):2993-3002. PMID: 24993944; PMCID: PMC4197660.
    4. Singh M, Castillo D, Patel CV, Patel RC. Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Biochemistry. 2011 May 31; 50(21):4550-60. PMID: 21526770.
      View in: PubMed
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