Loading...

David Castillo Azofeifa, PhD

Title(s)Postdoctoral Scholar, Orofacial Sciences
SchoolSchool of Dentistry
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Universidad de Costa RicaB.S.2006Biology
    University of South CarolinaPSM2010Biological Sciences
    University of Colorado Anschutz Medical CampusPh.D.2016Cell and Developmental Biology

    Collapse Overview 
    Collapse Overview
    The scientific area to which I have devoted most of my work is stem cell research. I am interested in signaling circuits that might regulate the stem/progenitor cell pool(s) within epithelial tissues, which are responsible for homeostatic maintenance and regeneration after injury. Uncovering key signals for stem cell proliferation and differentiation will provide new insights useful for disease treatments and regenerative medicine.

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Castillo-Azofeifa D, Fazio EN, Nattiv R, Good HJ, Wald T, Pest MA, de Sauvage FJ, Klein OD, Asfaha S. Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration. EMBO J. 2019 Jan 11. PMID: 30635334.
      View in: PubMed
    2. Castillo-Azofeifa D, Seidel K, Gross L, Golden EJ, Jacquez B, Klein OD, Barlow LA. SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis. Development. 2018 07 17; 145(14). PMID: 29945863.
      View in: PubMed
    3. McKinley KL, Stuurman N, Royer LA, Schartner C, Castillo-Azofeifa D, Delling M, Klein OD, Vale RD. Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. Elife. 2018 06 13; 7. PMID: 29897330.
      View in: PubMed
    4. Zou WY, Blutt SE, Zeng XL, Chen MS, Lo YH, Castillo-Azofeifa D, Klein OD, Shroyer NF, Donowitz M, Estes MK. Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation. Cell Rep. 2018 Jan 23; 22(4):1003-1015. PMID: 29386123.
      View in: PubMed
    5. Chukwurah E, Willingham V, Singh M, Castillo-Azofeifa D, Patel RC. Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT. J Cell Biochem. 2018 04; 119(4):3598-3607. PMID: 29231267.
      View in: PubMed
    6. Castillo-Azofeifa D, Losacco JT, Salcedo E, Golden EJ, Finger TE, Barlow LA. Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance. Development. 2017 09 01; 144(17):3054-3065. PMID: 28743797.
      View in: PubMed
    7. Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, Barlow LA. Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development. 2014 Aug; 141(15):2993-3002. PMID: 24993944; PMCID: PMC4197660.
      View in: PubMed, PubMed Central
    8. Singh M, Castillo D, Patel CV, Patel RC. Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Biochemistry. 2011 May 31; 50(21):4550-60. PMID: 21526770.
      View in: PubMed
    David's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (44) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (6) people
    _
    Similar People
    People who share similar concepts with this person.
    See all (60) people
    _
    Same Department
    Search Department
    ↑