David Hwang, MD

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
AddressLocation Required, #54K
Phone415-514-6919
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    Collapse Biography 
    Collapse Education and Training
    USC/Doheny Eye InstituteFellowship - Cornea, External Disease, and Refractive Surgery1990School of Medicine
    USC/Doheny Eye InstituteFellowship - Uveitis1990School of Medicine
    University of California, San FranciscoResidency - Ophthalmology1989School of Medicine
    University of California, San FranciscoResidency - Internal Medicine1986School of Medicine
    University of California, San FranciscoM.D.1984 School of Medicine
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Bestdoctors.com (previously Woodward & White, publisher)1996  - nowAmerica's Best Doctors (25 consecutive years to date)
    University of California, San Francisco2017The 2017 UCSF Exceptional Physician Award
    United States Congress (sponsor: Speaker of the House, Hon. Nancy P. Pelosi, California)2017Special Congressional Recognition in Honor of Outstanding and Invaluable Service to the Community
    United States Senate (sponsor: Hon. Dianne Feinstein, California)2017Recognition for Service in Ophthalmology and Leadership in Ophthalmological Research
    California State Senate2017Recognition in Honor of Exceptional Research in the Field of Ocular and Corneal Disease
    California State Assembly2017Certificate in Honor of Lifetime of Commitment to the Study and Advancement of Ophthalmology
    San Francisco Board of Supervisors2017Recognition of Distinction and Merit for Outstanding Service to the People of San Francisco
    The Glaucoma Foundation2017Glaucoma Foundation Honoree
    University of Nebraska2016Judy and C. David Fritch MD Lecturer
    Association for Research in Vision and Ophthalmology and The Cornea Society2015ARVO-Cornea Society VISTA Distinguished Scientific Lecturer
    University of California, San Francisco2015  - nowPearl T. and Samuel J. Kimura MD Endowed Chair in Ophthalmology
    American Academy of Ophthalmology2010Senior Achievement Award
    University of California, Berkeley School of Optometry2008Morgan-Sarver Lecturer
    Who's Who in America2001  - nowWho's Who in America, Life Member
    American Academy of Ophthalmology2000Honor Award
    University of California, San Francisco1998Steven G. Kramer Endowed Chair in Ophthalmology (5-year term)
    Focus Magazine1995Named in "Brain Trust: 101 People Who Make this The Smartest Place on Earth"
    University of California, San Francisco Department of Ophthalmology1994Kimura Award for Excellence in Teaching
    The Heed Foundation1990  - 1991Heed-Knapp Fellow (declined after appointment to faculty of UCSF)
    National Eye Institute, National Institutes of Health1989  - 1990National Research Service Award
    The Heed Foundation1989  - 1990Heed Fellow
    University of California, San Francisco Department of Ophthalmology1989Hogan Award for Outstanding Scientific Research
    University of California, San Francisco Department of Ophthalmology1988Asbury Award for Outstanding Clinical Research
    University of California San Francisco School of Medicine1984First Prize, UCSF Academic Excellence Award (achieved highest honors in every course over 4 years)
    University of California, San Francisco School of Medicine1984Medial school graduation rank: #1 of 144

    Collapse Overview 
    Collapse Overview
    A native of Illinois, USA, David G. Hwang, MD, FACS obtained both his undergraduate and medical degrees from the University of California, San Francisco (UCSF), graduating first in his medical school class in 1984. After two years of internal medical residency and three years of ophthalmology residency at UCSF, he completed concurrent fellowships in cornea and refractive surgery as well as uveitis at the University of Southern California/Doheny Eye Institute as a Heed Fellow. In 1990 he joined the full-time faculty at the University of California, San Francisco, where he is currently Professor and Vice Chair and holds the Pearl T. Kimura and Samuel J. Kimura MD Endowed Chair in Ophthalmology. He serves as Director of the Cornea Service, Director of the Refractive Surgery Service, and Associate of the Francis I. Proctor Foundation for Research in Ophthalmology at UCSF.

    Dr. Hwang has served in leadership and executive roles in a number of professional organizations, including President of the Ocular Microbiology and Immunology Group, Executive Secretary of the Max Fine Cornea Society, Medical Director of Ophthalmology at the UCSF Medical Center, and Medical Eye Bank Director of the UCSF Tissue Bank. He has chaired the joint American Academy of Ophthalmology (AAO)-Centers for Disease Control Task Force for the Use of Vancomycin in Ophthalmology and has served on the writing committee for the Cornea and External Disease volume of the AAO Basic and Clinical Science series, in which he was responsible for authoring and editing the section on ocular infectious and external eye disease.

    A committed educator, Dr. Hwang is active in the teaching of students, residents, and fellows and has received the Kimura Award for Excellence in Teaching from the UCSF Department of Ophthalmology. He has organized and taught numerous postgraduate courses and conferences at the regional, national, and international level and is a frequently invited speaker at national and international meetings. He has been the recipient of several named lectureships, been awarded the Honor Award and Senior Achievement Award from the American Academy of Ophthalmology, and been named to the “Best Doctors in the United States” list every year since 1996.

    Dr. Hwang’s university-based referral practice is focused on corneal, cataract, and refractive surgery, with special interests in ocular infectious disease, corneal endothelial dystrophies and diseases, and high-risk corneal transplantation. He has conducted translational research into cellular transplantation and gene therapy approaches to corneal endothelial disease. He described the relationship between inadequate dosing of topical fluoroquinolones and subsequent antimicrobial resistance, and he reported the pharmacodynamic and genomic mechanisms underlying such development. As a result of his investigations, Dr. Hwang widely advocated for changing prevailing antimicrobial prescribing patterns away from prolonged, intermittent, and/or tapering dosing towards short-term, suprathreshold dosing.

    His clinical interests include the development of innovative surgical techniques and instrumentation in corneal, cataract, and refractive surgery. He has published over 100 original articles and scientific abstracts and has co-authored two texts in cornea and refractive surgery. He resides in the San Francisco Bay Area with his wife, an ophthalmologist, and their three sons.

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sociodemographic Disparities in Preoperative Visual Acuity and Cataract Surgery Utilization in the San Francisco Bay Area. J Racial Ethn Health Disparities. 2024 Feb 08. Cho WKT, Hwang DG. PMID: 38329693.
      View in: PubMed   Mentions:    Fields:    
    2. Racial/Ethnic, Biomedical, and Sociodemographic Risk Factors for COVID-19 Positivity and Hospitalization in the San Francisco Bay Area. J Racial Ethn Health Disparities. 2023 08; 10(4):1653-1668. Cho WKT, Hwang DG. PMID: 35852709.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    3. Differential Effects of Race/Ethnicity and Social Vulnerability on COVID-19 Positivity, Hospitalization, and Death in the San Francisco Bay Area. J Racial Ethn Health Disparities. 2023 04; 10(2):834-843. Cho WKT, Hwang DG. PMID: 35239177; PMCID: PMC8893050.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. CENTRAL RETINAL ARTERY OCCLUSION WITH CILIORETINAL ARTERY SPARING AFTER LASER-ASSISTED IN SITU KERATOMILEUSIS. Retin Cases Brief Rep. 2021 Jul 01; 15(4):436-440. Francis AW, Zhu I, Borirakchanyavat S, Schwartz DM, Hwang DG. PMID: 30106799.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Eyecare provider attitudes toward and adoption of telehealth during the COVID-19 pandemic. J Cataract Refract Surg. 2021 04 01; 47(4):549-551. Liu Y, Ruan MZC, Haq Z, Hwang DG. PMID: 32897931; PMCID: PMC7478115.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    6. Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty. J Ophthalmol. 2020; 2020:6147248. Lee JH, Vu V, Lazcano-Gomez G, Han K, Suvannachart P, Rose-Nussbaumer J, Schallhorn J, Hwang D, Han Y. PMID: 32695499; PMCID: PMC7368213.
      View in: PubMed   Mentions: 2  
    7. Author Correction: Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy. Sci Rep. 2020 Feb 06; 10(1):2395. Pan P, Weisenberger DJ, Zheng S, Wolf M, Hwang DG, Rose-Nussbaumer JR, Jurkunas UV, Chan MF. PMID: 32024933; PMCID: PMC7002491.
      View in: PubMed   Mentions:    Fields:    
    8. Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy. Sci Rep. 2019 11 08; 9(1):16385. Pan P, Weisenberger DJ, Zheng S, Wolf M, Hwang DG, Rose-Nussbaumer JR, Jurkunas UV, Chan MF. PMID: 31705138; PMCID: PMC6841734.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Content validity of a novel patient-reported and observer-reported outcomes assessment to evaluate ocular symptoms associated with infectious conjunctivitis in both adult and pediatric populations. Health Qual Life Outcomes. 2019 Oct 30; 17(1):163. Sarda SP, De La Cruz M, Flood EM, Vanya M, Hwang DG, Ta CN, Narvekar A. PMID: 31666074; PMCID: PMC6820993.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. One-Year Efficacy and Safety of Combined Photorefractive Keratectomy and Accelerated Corneal Collagen Cross-Linking after Intacs SK Intracorneal Ring Segment Implantation in Moderate Keratoconus. Biomed Res Int. 2019; 2019:7850216. Koh IH, Seo KY, Park SB, Yang H, Kim I, Kim JS, Hwang DG, Nam SM. PMID: 31360724; PMCID: PMC6644267.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    11. Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1734-1747. Wolf M, Clay SM, Oldenburg CE, Rose-Nussbaumer J, Hwang DG, Chan MF. PMID: 31022731; PMCID: PMC6485316.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Necrotizing Scleritis After Cosmetic Conjunctivectomy With Mitomycin C. Am J Ophthalmol. 2018 10; 194:72-81. Ji YW, Park SY, Jung JW, Choi S, Alotaibi MH, Stulting RD, Hwang DG, Seo KY. PMID: 30053476.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Performance of Bio-Occlusive Dressing as Barrier Protection from Presurgical Chlorhexidine Skin Preparation. Curr Eye Res. 2018 05; 43(5):576-579. Brodie F, Bever G, Hwang DG. PMID: 29190159.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    14. Late extrusion of intrastromal corneal ring segments: A report of two cases. Am J Ophthalmol Case Rep. 2017 Dec; 8:67-70. Oatts JT, Savar L, Hwang DG. PMID: 29260121; PMCID: PMC5731710.
      View in: PubMed   Mentions: 5  
    15. Manual Removal of Intraocular Lens Silicone Oil Droplets and Dystrophic Calcifications Using a Nitinol Loop: A Case Series. Ophthalmic Surg Lasers Imaging Retina. 2017 05 01; 48(5):422-426. Moussa K, Leng T, Oatts JT, Bhisitkul RB, Hwang DG, Stewart JM. PMID: 28499054.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy. PLoS One. 2017; 12(4):e0175112. Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, Kemmer J, Weaver VM, Hwang DG, Chan MF. PMID: 28384203; PMCID: PMC5383226.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    17. Corneal Injury from Presurgical Chlorhexidine Skin Preparation. World Neurosurg. 2016 Dec; 96:610.e1-610.e4. Bever GJ, Brodie FL, Hwang DG. PMID: 27647026.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    18. Peculiar protuberance. JAMA Ophthalmol. 2014 Dec; 132(12):1483-4. Seider MI, Hwang DG, Damato BE. PMID: 25501400.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Usefulness of plasma epigenetic changes of five major genes involved in the pathogenesis of colorectal cancer. Int J Colorectal Dis. 2013 Jan; 28(1):139-47. Pack SC, Kim HR, Lim SW, Kim HY, Ko JY, Lee KS, Hwang D, Park SI, Kang H, Park SW, Hong GY, Hwang SM, Shin MG, Lee S. PMID: 22990173.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    20. Upside-down lens syndrome: ocular complications secondary to inverted implantation of the Kelman Multiflex anterior chamber intraocular lens. Am J Ophthalmol. 2011 Jul; 152(1):122-125.e2. Fintelmann RE, Kim SK, Hwang DG. PMID: 21570051; PMCID: PMC5410585.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Pharmacokinetics of azithromycin and moxifloxacin in human conjunctiva and aqueous humor during and after the approved dosing regimens. Am J Ophthalmol. 2010 Nov; 150(5):744-751.e2. Stewart WC, Crean CS, Zink RC, Brubaker K, Haque RM, Hwang DG. PMID: 20813346.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Acute angle-closure glaucoma due to iris transfixation of a subluxated posterior chamber intraocular lens-capsular bag complex. J Cataract Refract Surg. 2007 Sep; 33(9):1662-3. Rutar T, Hwang DG, Stamper RL. PMID: 17720091.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Outbreak of Fusarium keratitis in soft contact lens wearers in San Francisco. Arch Ophthalmol. 2006 Jul; 124(7):1051-3. Bernal MD, Acharya NR, Lietman TM, Strauss EC, McLeod SD, Hwang DG. PMID: 16769826.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsPHPublic Health
    24. Peripheral interstitial keratitis: a novel manifestation of ocular mastocytosis. Cornea. 2006 Apr; 25(3):364-7. Magone MT, Maric I, Hwang DG. PMID: 16633043.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Comparison of topographic corneal irregularity after LASIK and intrastromal corneal ring segments in the same patients. J Refract Surg. 2005 Nov-Dec; 21(6):722-6. Naseri A, Forseto AS, Francesconi CM, Hwang DG, Campos M, Nose W. PMID: 16329365.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Susceptibility of human corneal endothelial cells to HSV-1 infection. Curr Eye Res. 2005 Oct; 30(10):863-9. Sugioka K, Drake JD, Fukuda M, Shimomura Y, Hwang DG. PMID: 16251123.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    27. Effects of SV40 T antigen transduction on human corneal endothelial cell wound healing in vitro. J Ocul Pharmacol Ther. 2005 Oct; 21(5):353-66. Hsiao CH, Sah WJ, Soya K, Ma DH, Im YW, Zhang F, Hwang DG. PMID: 16245961.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Uveitis-associated flap edema and lamellar interface fluid collection after LASIK. Am J Ophthalmol. 2005 Jun; 139(6):1137-9. McLeod SD, Mather R, Hwang DG, Margolis TP. PMID: 15953462.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Acute zonal occult outer retinopathy in a patient with graft-versus-host disease. Am J Ophthalmol. 2004 Dec; 138(6):1058-60. Cheung MC, Nune GC, Hwang DG, Sutter EE, Duncan JL. PMID: 15629309.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Late-onset corneal haze and myopic regression after photorefractive keratectomy (PRK). Cornea. 2004 May; 23(4):350-5. Kuo IC, Lee SM, Hwang DG. PMID: 15097128.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    31. Relapsing diffuse lamellar keratitis after laser in situ keratomileusis associated with recurrent erosion syndrome. Arch Ophthalmol. 2004 Mar; 122(3):396-8. Jeng BH, Stewart JM, McLeod SD, Hwang DG. PMID: 15006861.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Fluoroquinolone resistance in ophthalmology and the potential role for newer ophthalmic fluoroquinolones. Surv Ophthalmol. 2004 Mar; 49 Suppl 2:S79-83. Hwang DG. PMID: 15028483.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    33. Atypical vortex pattern of corneal deposits in granular corneal dystrophy. Cornea. 2003 Nov; 22(8):754-9. Aldave AJ, Yellore VS, Hwang DG. PMID: 14576527.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    34. Inhibition of fibroblast-induced angiogenic phenotype of cultured endothelial cells by the overexpression of tissue inhibitor of metalloproteinase (TIMP)-3. J Biomed Sci. 2003 Sep-Oct; 10(5):526-34. Ma DH, Chen JI, Zhang F, Hwang DG, Chen JK. PMID: 12928593.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    35. Expression of tissue inhibitor of metalloproteinase-4 in normal human corneal cells and experimental corneal neovascularization. Ophthalmic Res. 2003 Jul-Aug; 35(4):199-207. Ma DH, Zhang F, Shi W, Yao JY, Hsiao CH, Wu HC, Kim WS, Hao YX, Hwang DG, Chen JK, Tsai RJ. PMID: 12815195.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    36. CD40 expression in normal human cornea and regulation of CD40 in cultured human corneal epithelial and stromal cells. Invest Ophthalmol Vis Sci. 2002 Feb; 43(2):348-57. Iwata M, Soya K, Sawa M, Sakimoto T, Hwang DG. PMID: 11818376.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
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