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David Jablons, MD

Title(s)Professor, Surgery
SchoolSchool of Medicine
Address500 Parnassus Avenue
San Francisco CA 94117
Phone415-353-7502
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    Collapse Biography 
    Collapse Awards and Honors
    University of California, San Francisco 1999Surgical Resident Teaching Award
    University of California, San Francisco2001Surgical Resident Teaching Award

    Collapse Overview 
    Collapse Overview
    David M. Jablons M.D., FACS is Professor and Chief of the Section of General Thoracic Surgery at UCSF, and Program Leader of Thoracic Oncology. Dr. Jablons is also Ada Distinguished Professor in Thoracic Oncology and Nan T. McEvoy Distinguished Professor of Thoracic Surgical Oncology. Dr. Jablons is Director of the Thoracic Oncology Lab, one of the largest in the Department of Surgery, with seven principal investigators, an enviable portfolio of NIH grants, and state-of-art-equipment. Utilizing next generation sequencing and leveraging one of the largest thoracic tissue banks in the world, the lab has compiled an enviable record of scientific discovery and invention including a life-saving prognostic assay that informs the decision for providing adjuvant therapy to early-stage lung cancer patients.

    Dr. Jablons received his medical degree from Albany Medical College. During medical school, he was awarded an NCI preceptorship allowing him to train under Steven Rosenberg, a world-renowned surgeon and tumor immunologist. This experience kindled Dr. Jablons lifelong interest in translational and precision medicine. Dr. Jablons then completed his general surgery residency at Tufts-New England Medical Center and his thoracic surgery residency at what is now New York Presbyterian-Weill Cornell Medical Center. His mentors included Robert Ginsburg at Memorial Sloan-Kettering and David Sugarbaker at Brigham & Women's Hospital, both world-renown thoracic surgical oncologists. Dr. Jablons also served as a Navy commander while Chief of Thoracic Surgery at the Oakland Naval Hospital. In 1997, he was named Chief of General Thoracic Surgery at UCSF.

    Dr. Jablons is a highly accomplished thoracic surgeon, widely sought out by patients in the Bay Area and world-wide. One patient, Bonnie J. Addario, after recovering from an arduous lung cancer surgery, started a foundation bearing her name she co-founded with Dr. Jablons. Today, the Addario Foundation is one of the leading underwriters of lung cancer research. Dr. Jablons has also been a dedicated teacher and outstanding mentor for both for clinical fellows and surgical residents, the latter including Dan Raz and Johannes Kratz, protégés with an enviable and prolific record of publications who helped spearhead development of predictive and prognostic tools for lung cancer treatment in the lab.

    Dr. Jablons has been a trailblazer in educational outreach, co-founding the UCSF Thoracic Oncology Conference, an annual symposium that provided expert training for thousands of community surgeons for over a decade. He also was instrumental in establishing the China Clinical Trials Consortium to find more effective treatments for lung cancer, and to ameliorate the epidemic of lung cancer in China. In 2009, he led the effort to bring World Conference on Lung Cancer to San Francisco, the preeminent event in the field, in which he served as co-Chair.

    He is a member of numerous professional organizations including the Society of Thoracic Surgeons, the American College of Chest Physicians, the American Association for Cancer Research and the International Association for the Study of Lung Cancer (IASLC). Highly respected by his peers, Dr. Jablons was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty. Dr. Jablons was recently inducted into the American Surgical Society, the nation's most prestigious.

    Collapse Research 
    Collapse Research Activities and Funding
    Inflammation and Lung Carcinogenesis
    NIH/NCI R01CA132566May 1, 2008 - Mar 31, 2014
    Role: Principal Investigator
    The Wnt Pathway in Malignant Mesothelioma
    NIH/NCI R01CA093708Mar 1, 2005 - Feb 28, 2010
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial. JAMA Netw Open. 2020 Sep 01; 3(9):e209750. Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS. PMID: 32997124.
      View in: PubMed   Mentions:    Fields:    
    2. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 Aug 07. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576.
      View in: PubMed   Mentions:    Fields:    
    3. AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers. Am J Cancer Res. 2020; 10(8):2649-2676. Lemjabbar-Alaoui H, Peto CJ, Yang YW, Jablons DM. PMID: 32905466.
      View in: PubMed   Mentions:
    4. The Crosstalk between Src and Hippo/YAP Signaling Pathways in Non-Small Cell Lung Cancer (NSCLC). Cancers (Basel). 2020 May 26; 12(6). Hsu PC, Yang CT, Jablons DM, You L. PMID: 32466572.
      View in: PubMed   Mentions:
    5. Surgery for pleural mesothelioma, when it is indicated and why: arguments against surgery for malignant pleural mesothelioma. Transl Lung Cancer Res. 2020 Feb; 9(Suppl 1):S86-S91. Woodard GA, Jablons DM. PMID: 32206574.
      View in: PubMed   Mentions:
    6. Perioperative Lung Resection Outcomes After Implementation of a Multidisciplinary, Evidence-based Thoracic ERAS Program. Ann Surg. 2019 Dec 05. Haro GJ, Sheu B, Marcus SG, Sarin A, Campbell L, Jablons DM, Kratz JR. PMID: 31851005.
      View in: PubMed   Mentions:    Fields:    
    7. Inhibition of cyclin-dependent kinase 7 down-regulates yes-associated protein expression in mesothelioma cells. J Cell Mol Med. 2020 01; 24(1):1087-1098. Miao J, Kyoyama H, Liu L, Chan G, Wang Y, Urisman A, Yang YL, Liu S, Xu Z, Bin H, Li H, Jablons DM, You L. PMID: 31755214.
      View in: PubMed   Mentions: 2     Fields:    
    8. Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma. Cancer Manag Res. 2019; 11:8209-8218. Jiang L, Tolani B, Yeh CC, Fan Y, Reza JA, Horvai AE, Xia E, Kratz JR, Jablons DM, Mann MJ. PMID: 31686913.
      View in: PubMed   Mentions:
    9. Case report: recurrent metastatic breast cancer in internal mammary dissection bed discovered at the time of coronary bypass. J Cardiothorac Surg. 2019 Sep 05; 14(1):158. Woodard GA, Lee H, Fels Elliott DR, Jones KD, Wong J, Jablons DM, Ihnken K. PMID: 31488186.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC). Int J Mol Sci. 2019 Aug 05; 20(15). Hsu PC, Jablons DM, Yang CT, You L. PMID: 31387256.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region. J Biol Chem. 2019 09 13; 294(37):13545-13559. Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N. PMID: 31341017.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. CA Cancer J Clin. 2019 09; 69(5):402-429. Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. PMID: 31283845.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansPHPublic Health
    13. Cucurbitacin E inhibits the Yes-associated protein signaling pathway and suppresses brain metastasis of human non-small cell lung cancer in a murine model. Oncol Rep. 2019 Aug; 42(2):697-707. Hsu PC, Tian B, Yang YL, Wang YC, Liu S, Urisman A, Yang CT, Xu Z, Jablons DM, You L. PMID: 31233205.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10. Cancers (Basel). 2019 May 02; 11(5). Hung MS, Chen YC, Lin P, Li YC, Hsu CC, Lung JH, You L, Xu Z, Mao JH, Jablons DM, Yang CT. PMID: 31052599.
      View in: PubMed   Mentions:
    15. Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging. J Thorac Oncol. 2019 07; 14(7):1223-1232. Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ. PMID: 30959120.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Applications of Next-Generation Sequencing in Neoantigen Prediction and Cancer Vaccine Development. Genet Test Mol Biomarkers. 2020 Feb; 24(2):59-66. Lancaster EM, Jablons D, Kratz JR. PMID: 30907630.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer. Biomedicines. 2018 Dec 07; 6(4). Hsu PC, Yang CT, Jablons DM, You L. PMID: 30544524.
      View in: PubMed   Mentions:
    18. Pathologic Complete Response to Neoadjuvant Crizotinib in a Lung Adenocarcinoma Patient With a MET Exon 14 Skipping Mutation. Clin Lung Cancer. 2019 03; 20(2):e137-e141. Rotow JK, Woodard GA, Urisman A, McCoach CE, Bivona TG, Elicker BM, Jablons DM, Blakely CM. PMID: 30553716.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Central Airway Obstruction Due to Tracheal Glomus Tumor. Thorac Cardiovasc Surg Rep. 2018 Jan; 7(1):e43-e45. Haro GJ, Seeley EJ, Jablons DM, Kratz JR. PMID: 30464882.
      View in: PubMed   Mentions:
    20. Scientific Advances and New Frontiers in Mesothelioma Therapeutics. J Thorac Oncol. 2018 09; 13(9):1269-1283. Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R. PMID: 29966799.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    21. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 10 01; 128(10):4343-4358. Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. PMID: 29999500.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    22. Transfer of multiple loci of donor's genes to induce recipient tolerance in organ transplantation. Exp Ther Med. 2018 Jun; 15(6):4961-4971. Li T, Zhang W, Xu Q, Li S, Tong X, Ding J, Li H, Hou S, Xu Z, Jablons DM, You L. PMID: 29844800.
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    23. Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model. J Cell Mol Med. 2018 06; 22(6):3073-3085. Hsu PC, Miao J, Huang Z, Yang YL, Xu Z, You J, Dai Y, Yeh CC, Chan G, Liu S, Urisman A, Yang CT, Jablons DM, You L. PMID: 29575527.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    24. Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma. J Cell Mol Med. 2018 06; 22(6):3139-3148. Hsu PC, Miao J, Wang YC, Zhang WQ, Yang YL, Wang CW, Yang CT, Huang Z, You J, Xu Z, Jablons DM, You L. PMID: 29575535.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    25. Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog. Oncotarget. 2018 03 06; 9(18):14311-14323. Tolani B, Hoang NT, Acevedo LA, Giroux Leprieur E, Li H, He B, Jablons DM. PMID: 29581846.
      View in: PubMed   Mentions: 2     Fields:    
    26. Old Sonic Hedgehog, new tricks: a new paradigm in thoracic malignancies. Oncotarget. 2018 03 06; 9(18):14680-14691. Giroux Leprieur E, Jablons DM, He B. PMID: 29581874.
      View in: PubMed   Mentions: 4     Fields:    
    27. YAP regulates PD-L1 expression in human NSCLC cells. Oncotarget. 2017 Dec 29; 8(70):114576-114587. Miao J, Hsu PC, Yang YL, Xu Z, Dai Y, Wang Y, Chan G, Huang Z, Hu B, Li H, Jablons DM, You L. PMID: 29383103.
      View in: PubMed   Mentions: 19     Fields:    
    28. Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma. Oncotarget. 2018 Jan 02; 9(1):853-865. Wang L, Jin JQ, Zhou Y, Tian Z, Jablons DM, He B. PMID: 29416661.
      View in: PubMed   Mentions: 4     Fields:    
    29. Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer. Oncotarget. 2017 11 28; 8(61):103744-103757. Giroux Leprieur E, Tolani B, Li H, Leguay F, Hoang NT, Acevedo LA, Jin JQ, Tseng HH, Yue D, Kim IJ, Wislez M, Wang C, Jablons DM, He B. PMID: 29262597.
      View in: PubMed   Mentions: 7     Fields:    
    30. Checkpoint inhibitor is active against large cell neuroendocrine carcinoma with high tumor mutation burden. J Immunother Cancer. 2017 09 19; 5(1):75. Wang VE, Urisman A, Albacker L, Ali S, Miller V, Aggarwal R, Jablons D. PMID: 28923100.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    31. Hippo pathway in lung development. J Thorac Dis. 2017 Aug; 9(8):2246-2250. Dai Y, Jablons D, You L. PMID: 28932516.
      View in: PubMed   Mentions:
    32. Systematic comparison of two whole-genome amplification methods for targeted next-generation sequencing using frozen and FFPE normal and cancer tissues. Sci Rep. 2017 06 22; 7(1):4055. Mendez P, Fang LT, Jablons DM, Kim IJ. PMID: 28642587.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Drug development against the hippo pathway in mesothelioma. Transl Lung Cancer Res. 2017 Jun; 6(3):335-342. Woodard GA, Yang YL, You L, Jablons DM. PMID: 28713678.
      View in: PubMed   Mentions:
    34. Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2018 01; 19(1):58-64. Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM. PMID: 28645632.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. DCLK1 is correlated with MET and ERK5 expression, and associated with prognosis in malignant pleural mesothelioma. Int J Oncol. 2017 Jul; 51(1):91-103. Wang H, Dai YY, Zhang WQ, Hsu PC, Yang YL, Wang YC, Chan G, Au A, Xu ZD, Jiang SJ, Wang W, Jablons DM, You L. PMID: 28560410.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    36. Targeting YAP in malignant pleural mesothelioma. J Cell Mol Med. 2017 Nov; 21(11):2663-2676. Zhang WQ, Dai YY, Hsu PC, Wang H, Cheng L, Yang YL, Wang YC, Xu ZD, Liu S, Chan G, Hu B, Li H, Jablons DM, You L. PMID: 28470935.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    37. Management of Lung Cancer Invading the Superior Sulcus. Thorac Surg Clin. 2017 May; 27(2):149-157. Kratz JR, Woodard G, Jablons DM. PMID: 28363369.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device. PLoS One. 2017; 12(4):e0174696. Yoon JH, Kim TW, Mendez P, Jablons DM, Kim IJ. PMID: 28403238.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells. Oncotarget. 2017 Jan 17; 8(3):4096-4109. Dai Y, Liu S, Zhang WQ, Yang YL, Hang P, Wang H, Cheng L, Hsu PC, Wang YC, Xu Z, Jablons DM, You L. PMID: 27911857.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    40. Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas. Oncotarget. 2016 Dec 06; 7(49):80415-80425. Li H, Yue D, Jin JQ, Woodard GA, Tolani B, Luh TM, Giroux-Leprieur E, Mo M, Chen Z, Che J, Zhang Z, Zhou Y, Wang L, Hao X, Jablons D, Wang C, He B. PMID: 27533453.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    41. FAIM2, as a novel diagnostic maker and a potential therapeutic target for small-cell lung cancer and atypical carcinoid. Sci Rep. 2016 Sep 28; 6:34022. Kang HC, Kim JI, Chang HK, Woodard G, Choi YS, Ku JL, Jablons DM, Kim IJ. PMID: 27677402.
      View in: PubMed   Mentions: 1     Fields:    
    42. Hybrid minimally invasive Ivor Lewis esophagectomy after neoadjuvant chemoradiation yields excellent long-term survival outcomes with minimal morbidity. J Surg Oncol. 2016 Dec; 114(7):838-847. Woodard GA, Crockard JC, Clary-Macy C, Zoon-Besselink CT, Jones K, Korn WM, Ko AH, Gottschalk AR, Rogers SJ, Jablons DM. PMID: 27569043.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    43. Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation. Int J Oncol. 2016 Oct; 49(4):1755-65. Dang J, Mendez P, Lee S, Kim JW, Yoon JH, Kim TW, Sailey CJ, Jablons DM, Kim IJ. PMID: 27511764.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. YAP promotes erlotinib resistance in human non-small cell lung cancer cells. Oncotarget. 2016 Aug 09; 7(32):51922-51933. Hsu PC, You B, Yang YL, Zhang WQ, Wang YC, Xu Z, Dai Y, Liu S, Yang CT, Li H, Hu B, Jablons DM, You L. PMID: 27409162.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    45. Spotlight on afatinib and its potential in the treatment of squamous cell lung cancer: the evidence so far. Ther Clin Risk Manag. 2016; 12:807-16. Xu Y, Ding VW, Zhang H, Zhang X, Jablons D, He B. PMID: 27307741.
      View in: PubMed   Mentions:
    46. Comprehensive evaluation and validation of targeted next-generation sequencing performance in two clinical laboratories. Int J Oncol. 2016 Jul; 49(1):235-42. Mendez P, Dang J, Kim JW, Lee S, Yoon JH, Kim T, Sailey CJ, Jablons DM, Kim IJ. PMID: 27121194.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells. J Cell Mol Med. 2016 07; 20(7):1295-306. Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Lung JH, Yang CT, Liu ST. PMID: 26969027.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    48. Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas. Oncotarget. 2016 Feb 16; 7(7):8321-31. Kang HC, Kim HK, Lee S, Mendez P, Kim JW, Woodard G, Yoon JH, Jen KY, Fang LT, Jones K, Jablons DM, Kim IJ. PMID: 26824986.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    49. SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer. PLoS One. 2016; 11(2):e0148911. Lui NS, Yang YW, van Zante A, Buchanan P, Jablons DM, Lemjabbar-Alaoui H. PMID: 26882224.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    50. Lung Cancer Staging and Prognosis. Cancer Treat Res. 2016; 170:47-75. Woodard GA, Jones KD, Jablons DM. PMID: 27535389.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    51. Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells. Oncol Rep. 2015 Dec; 34(6):3187-95. Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Hsieh MJ, Lin YC, Yang CT, Liu ST, Tsai YH. PMID: 26503734.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    52. Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma. J Cell Mol Med. 2015 Oct; 19(10):2385-96. Yang YL, Ni J, Hsu PC, Mao JH, Hsieh D, Xu A, Chan G, Au A, Xu Z, Jablons DM, You L. PMID: 26218750.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    53. EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas. PLoS One. 2015; 10(7):e0132134. Yue D, Li H, Che J, Zhang Y, Tolani B, Mo M, Zhang H, Zheng Q, Yang Y, Cheng R, Jin JQ, Luh TW, Yang C, Tseng HH, Giroux-Leprieur E, Woodard GA, Hao X, Wang C, Jablons DM, He B. PMID: 26132438.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    54. Operative and Perioperative Pulmonary Emboli. Thorac Surg Clin. 2015 Aug; 25(3):289-99. Cox JC, Jablons DM. PMID: 26210925.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    55. Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene. Thorac Cancer. 2015 Jul; 6(4):480-7. Wang Y, Xu Z, Mao JH, Hung MS, Hsieh D, Au A, Jablons DM, You L. PMID: 26273405.
      View in: PubMed   Mentions: 1     Fields:    
    56. PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer. Zhongguo Fei Ai Za Zhi. 2015 Jun; 18(6):345-50. Wang Y, Xu Z, Mao JH, Hsieh D, Au A, Jablons DM, Li H, You L. PMID: 26104890.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    57. Transforming Growth Factor-ß and Interleukin-1ß Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 Jun 05; 290(23):14717-28. Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL. PMID: 25918170.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    58. NF-?B-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer. Cell Rep. 2015 Apr 07; 11(1):98-110. Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, Krogan NJ, Bivona TG. PMID: 25843712.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    59. Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14. Front Genet. 2015; 6:67. Letteboer TG, Benzinou M, Merrick CB, Quigley DA, Zhau K, Kim IJ, To MD, Jablons DM, van Amstel JK, Westermann CJ, Giraud S, Dupuis-Girod S, Lesca G, Berg JH, Balmain A, Akhurst RJ. PMID: 25815003.
      View in: PubMed   Mentions:
    60. Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells. Oncotarget. 2015 Feb 28; 6(6):4357-68. You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L. PMID: 25738359.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    61. Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma. Oncol Rep. 2015 Apr; 33(4):2052-60. Hirata T, Zheng Q, Chen Z, Kinoshita H, Okamoto J, Kratz J, Li H, Lui N, Do H, Cheng T, Tseng HH, Koizumi K, Shimizu K, Zhou HM, Jablons D, He B. PMID: 25632963.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
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    67. Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity. Am J Clin Oncol. 2014 Aug; 37(4):350-5. Okoye CC, Jablons DM, Jahan TM, Kukreja J, Cardozo S, Yom SS. PMID: 23357970.
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    133. Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma. J Thorac Oncol. 2008 Oct; 3(10):1089-95. Okamoto J, Mikami I, Tominaga Y, Kuchenbecker KM, Lin YC, Bravo DT, Clement G, Yagui-Beltran A, Ray MR, Koizumi K, He B, Jablons DM. PMID: 18827603.
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    134. A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma. Clin Cancer Res. 2008 Sep 01; 14(17):5565-70. Raz DJ, Ray MR, Kim JY, He B, Taron M, Skrzypski M, Segal M, Gandara DR, Rosell R, Jablons DM. PMID: 18765549.
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    135. Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung. Clin Cancer Res. 2008 Aug 01; 14(15):4794-9. Skrzypski M, Jassem E, Taron M, Sanchez JJ, Mendez P, Rzyman W, Gulida G, Raz D, Jablons D, Provencio M, Massuti B, Chaib I, Perez-Roca L, Jassem J, Rosell R. PMID: 18676750.
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    136. Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis. Head Neck. 2008 Jul; 30(7):946-63. Chou J, Lin YC, Kim J, You L, Xu Z, He B, Jablons DM. PMID: 18446839.
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    137. Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor-mediated transcription. . 2008 Jun; 7(6):1633-8. You L, Xu Z, Punchihewa C, Jablons DM, Fujii N. PMID: 18566234.
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    138. mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):576-83. Wilson SM, Barbone D, Yang TM, Jablons DM, Bueno R, Sugarbaker DJ, Nishimura SL, Gordon GJ, Broaddus VC. PMID: 18511708.
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    139. Adjuvant treatment of stage IB NSCLC: the problem of stage subset heterogeneity. Oncology (Williston Park). 2008 Apr 30; 22(5):511-6; discussion 516, 521-3. Calhoun R, Jablons D, Lau D, Gandara DR. PMID: 18533401.
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    140. Translational research in glioblastoma multiforme: molecular criteria for patient selection. Future Oncol. 2008 Apr; 4(2):219-28. Rosell R, de Las Peñas R, Balaña C, Santarpia M, Salazar F, de Aguirre I, Reguart N, Villa S, Wei J, Ramirez JL, Molina MA, Ramon y Cajal S, Jablons D, Taron M. PMID: 18407735.
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    141. Unmet need in lung cancer: can vaccines bridge the gap? Clin Lung Cancer. 2008 Feb; 9 Suppl 1:S6-12. Kim J, Raz D, Jablons D. PMID: 18540529.
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    142. Pharmacogenomic approaches to individualizing chemotherapy for non-small-cell lung cancer: current status and new directions. Clin Lung Cancer. 2008; 9 Suppl 3:S129-38. Gautschi O, Mack PC, Davies AM, Jablons DM, Rosell R, Gandara DR. PMID: 19419927.
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    143. Optimal surgical management of Stage I non-small-cell lung cancer in an increasingly aging population: challenges and recent progress. Expert Rev Respir Med. 2007 Dec; 1(3):343-53. Yagui-Beltrán A, Jablons DM. PMID: 20477174.
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    144. Epigenetic regulation of RhoB loss of expression in lung cancer. BMC Cancer. 2007 Nov 30; 7:220. Mazières J, Tovar D, He B, Nieto-Acosta J, Marty-Detraves C, Clanet C, Pradines A, Jablons D, Favre G. PMID: 18047684.
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    145. Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus. Cancer Sci. 2008 Jan; 99(1):46-53. Clément G, Guilleret I, He B, Yagui-Beltrán A, Lin YC, You L, Xu Z, Shi Y, Okamoto J, Benhattar J, Jablons D. PMID: 18005197.
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    146. Targeting the Wnt signaling pathway with dishevelled and cisplatin synergistically suppresses mesothelioma cell growth. Anticancer Res. 2007 Nov-Dec; 27(6B):4239-42. Uematsu K, Seki N, Seto T, Isoe C, Tsukamoto H, Mikami I, You L, He B, Xu Z, Jablons DM, Eguchi K. PMID: 18225596.
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    147. Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest. 2007 Nov; 117(11):3551-62. Araya J, Cambier S, Markovics JA, Wolters P, Jablons D, Hill A, Finkbeiner W, Jones K, Broaddus VC, Sheppard D, Barzcak A, Xiao Y, Erle DJ, Nishimura SL. PMID: 17965775.
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    148. Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells. Int J Cancer. 2007 Sep 15; 121(6):1175-81. Shi Y, He B, Kuchenbecker KM, You L, Xu Z, Mikami I, Yagui-Beltran A, Clement G, Lin YC, Okamoto J, Bravo DT, Jablons DM. PMID: 17534895.
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    149. Roles of secreted frizzled-related proteins in cancer. Acta Pharmacol Sin. 2007 Sep; 28(9):1499-504. Shi Y, He B, You L, Jablons DM. PMID: 17723183.
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    150. Diagnosis and treatment of bronchioloalveolar carcinoma. Curr Opin Pulm Med. 2007 Jul; 13(4):290-6. Raz DJ, Kim JY, Jablons DM. PMID: 17534175.
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    151. Adjuvant chemotherapy of stage I non-small cell lung cancer in North America. J Thorac Oncol. 2007 Jul; 2(7 Suppl 3):S125-7. Gandara DR, Wakelee H, Calhoun R, Jablons D. PMID: 17603308.
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    152. Impact of induction treatment on postoperative complications in the treatment of non-small cell lung cancer. J Thorac Oncol. 2007 Jul; 2(7):626-31. Brouchet L, Bauvin E, Marcheix B, Bigay-Game L, Renaud C, Berjaud J, Falcoze PE, Venissac N, Raz D, Jablons D, Mazières J, Dahan M. PMID: 17607118.
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    153. EGFR expression and mutational analysis as a predictive test. J Clin Oncol. 2007 May 20; 25(15):2144; author reply 2144-5. Raz DJ, Jablons DM. PMID: 17513827.
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    154. Natural history of stage I non-small cell lung cancer: implications for early detection. Chest. 2007 Jul; 132(1):193-9. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM. PMID: 17505036.
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    155. Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: clinical implications for the subsequent management of the brain. Cancer. 2007 Apr 15; 109(8):1668-75. Chen AM, Jahan TM, Jablons DM, Garcia J, Larson DA. PMID: 17342770.
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    156. Update on the molecular biology of malignant mesothelioma. Cancer. 2007 Apr 15; 109(8):1454-61. Lee AY, Raz DJ, He B, Jablons DM. PMID: 17348013.
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    157. Five-gene signature in non-small-cell lung cancer. N Engl J Med. 2007 Apr 12; 356(15):1582; author reply 1583. Raz DJ, Jablons DM. PMID: 17436432.
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    158. Wnt inhibitory factor-1 gene transfer inhibits melanoma cell growth. Hum Gene Ther. 2007 Apr; 18(4):379-86. Lin YC, You L, Xu Z, He B, Yang CT, Chen JK, Mikami I, Clément G, Shi Y, Kuchenbecker K, Okamoto J, Kashani-Sabet M, Jablons DM. PMID: 17472570.
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    159. Targeting the Wnt signaling pathway to treat Barrett's esophagus. Expert Opin Ther Targets. 2007 Mar; 11(3):375-89. Clément G, Jablons DM, Benhattar J. PMID: 17298295.
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    160. Wnt inhibitory factor inhibits lung cancer cell growth. J Thorac Cardiovasc Surg. 2007 Mar; 133(3):733-7. Kim J, You L, Xu Z, Kuchenbecker K, Raz D, He B, Jablons D. PMID: 17320573.
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    161. Clinical characteristics and survival of patients with surgically resected, incidentally detected lung cancer. J Thorac Oncol. 2007 Feb; 2(2):125-30. Raz DJ, Glidden DV, Odisho AY, Jablons DM. PMID: 17410027.
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    162. An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth. Cancer Res. 2007 Jan 15; 67(2):573-9. Fujii N, You L, Xu Z, Uematsu K, Shan J, He B, Mikami I, Edmondson LR, Neale G, Zheng J, Guy RK, Jablons DM. PMID: 17234765.
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    163. Stathmin is overexpressed in malignant mesothelioma. Anticancer Res. 2007 Jan-Feb; 27(1A):39-44. Kim JY, Harvard C, You L, Xu Z, Kuchenbecker K, Baehner R, Jablons D. PMID: 17352214.
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    164. Patterns of metastasis in human solid cancers. Cancer Treat Res. 2007; 135:209-21. Leong SP, Cady B, Jablons DM, Garcia-Aguilar J, Reintgen D, Werner JA, Kitagawa Y. PMID: 17953419.
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    165. Tumor fluoro-2-deoxy-D-glucose avidity on positron emission tomographic scan predicts mortality in patients with early-stage pure and mixed bronchioloalveolar carcinoma. J Thorac Cardiovasc Surg. 2006 Nov; 132(5):1189-95. Raz DJ, Odisho AY, Franc BL, Jablons DM. PMID: 17059942.
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    166. Novel therapies targeting signaling pathways in lung cancer. Thorac Surg Clin. 2006 Nov; 16(4):379-96, vi. Yagui-Beltrán A, He B, Raz D, Kim J, Jablons DM. PMID: 17240825.
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    167. Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancer. J Thorac Oncol. 2006 Nov; 1(9):943-8. Raz DJ, Zell JA, Karnezis AN, Odisho A, Ignatius Ou SH, Anton-Culver H, Jablons DM. PMID: 17409976.
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    168. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006 Jul; 10(1):39-50. Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA. PMID: 16843264.
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    169. Current concepts in bronchioloalveolar carcinoma biology. Clin Cancer Res. 2006 Jun 15; 12(12):3698-704. Raz DJ, He B, Rosell R, Jablons DM. PMID: 16778095.
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    170. Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX vaccine in advanced-stage non-small-cell lung cancer. Cancer Gene Ther. 2006 Jun; 13(6):555-62. Nemunaitis J, Jahan T, Ross H, Sterman D, Richards D, Fox B, Jablons D, Aimi J, Lin A, Hege K. PMID: 16410826.
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    171. Clinical patterns of metastasis. Cancer Metastasis Rev. 2006 Jun; 25(2):221-32. Leong SP, Cady B, Jablons DM, Garcia-Aguilar J, Reintgen D, Jakub J, Pendas S, Duhaime L, Cassell R, Gardner M, Giuliano R, Archie V, Calvin D, Mensha L, Shivers S, Cox C, Werner JA, Kitagawa Y, Kitajima M. PMID: 16770534.
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    172. Bronchioloalveolar carcinoma is not associated with younger age at diagnosis: an analysis of the SEER database. J Thorac Oncol. 2006 May; 1(4):339-43. Raz DJ, Jablons DM. PMID: 17409881.
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    173. Bronchioloalveolar carcinoma: a review. Clin Lung Cancer. 2006 Mar; 7(5):313-22. Raz DJ, He B, Rosell R, Jablons DM. PMID: 16640802.
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    174. Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma. Biochem Biophys Res Commun. 2006 Apr 21; 342(4):1228-32. Batra S, Shi Y, Kuchenbecker KM, He B, Reguart N, Mikami I, You L, Xu Z, Lin YC, Clément G, Jablons DM. PMID: 16516163.
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    175. Future directions in the second-line treatment of non-small cell lung cancer. Semin Oncol. 2006 Feb; 33(1 Suppl 1):S45-51. Rosell R, Cecere F, Cognetti F, Cuello M, Sanchez JM, Taron M, Reguart N, Jablons D. PMID: 16472709.
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    176. Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. Biochem Biophys Res Commun. 2006 Mar 10; 341(2):635-40. Lin YC, You L, Xu Z, He B, Mikami I, Thung E, Chou J, Kuchenbecker K, Kim J, Raz D, Yang CT, Chen JK, Jablons DM. PMID: 16427602.
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    177. Wnt-1 signal as a potential cancer therapeutic target. Drug News Perspect. 2006 Jan-Feb; 19(1):27-31. You L, Kim J, He B, Xu Z, McCormick F, Jablons DM. PMID: 16550254.
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    178. Wnt signaling in stem cells and lung cancer. Ernst Schering Found Symp Proc. 2006; (5):27-58. He B, Jablons DM. PMID: 17939294.
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    179. The role of Wnt signaling in cancer and stem cells. Future Oncol. 2005 Dec; 1(6):787-97. Reguart N, He B, Taron M, You L, Jablons DM, Rosell R. PMID: 16556058.
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    180. Wnt2 as a new therapeutic target in malignant pleural mesothelioma. Int J Cancer. 2005 Nov 01; 117(2):326-32. Mazieres J, You L, He B, Xu Z, Twogood S, Lee AY, Reguart N, Batra S, Mikami I, Jablons DM. PMID: 15900580.
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    181. A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance. Am J Respir Cell Mol Biol. 2005 Dec; 33(6):541-8. Kim KU, Wilson SM, Abayasiriwardana KS, Collins R, Fjellbirkeland L, Xu Z, Jablons DM, Nishimura SL, Broaddus VC. PMID: 16123394.
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    182. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res. 2005 Aug 15; 11(16):5878-85. Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, Zamora L, Mate JL, Manegold C, Ono M, Queralt C, Jahan T, Sanchez JJ, Sanchez-Ronco M, Hsue V, Jablons D, Sanchez JM, Moran T. PMID: 16115929.
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    183. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene. 2005 Aug 11; 24(34):5396-400. Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. PMID: 16007226.
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    184. Wnt signaling in stem cells and non-small-cell lung cancer. Clin Lung Cancer. 2005 Jul; 7(1):54-60. He B, Barg RN, You L, Xu Z, Reguart N, Mikami I, Batra S, Rosell R, Jablons DM. PMID: 16098245.
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    185. Efficacy of Wnt-1 monoclonal antibody in sarcoma cells. BMC Cancer. 2005 May 24; 5:53. Mikami I, You L, He B, Xu Z, Batra S, Lee AY, Mazieres J, Reguart N, Uematsu K, Koizumi K, Jablons DM. PMID: 15913453.
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    186. Wnt signaling in lung cancer. Cancer Lett. 2005 May 10; 222(1):1-10. Mazieres J, He B, You L, Xu Z, Jablons DM. PMID: 15837535.
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    187. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene. 2005 Apr 21; 24(18):3054-8. He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. PMID: 15735684.
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    188. Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus. J Clin Oncol. 2005 Apr 20; 23(12):2859-61. Hansen EK, Krieg RM, Azar RJ, Jablons DM, Jahan TM, Zaloudek CJ. PMID: 15838001.
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    189. Changes in radiographic abnormalities in organ donors: associations with lung transplantation. J Heart Lung Transplant. 2005 Mar; 24(3):323-30. McCowin MJ, Hall TS, Babcock WD, Solinger LL, Hall KW, Jablons DM. PMID: 15737760.
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    190. Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion. Chest. 2005 Mar; 127(3):909-15. Dresler CM, Olak J, Herndon JE, Richards WG, Scalzetti E, Fleishman SB, Kernstine KH, Demmy T, Jablons DM, Kohman L, Daniel TM, Haasler GB, Sugarbaker DJ. PMID: 15764775.
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    191. Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. Cancer Res. 2005 Feb 01; 65(3):743-8. He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM. PMID: 15705870.
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    192. Salmonella infection in an anterior mediastinal mass. J Thorac Cardiovasc Surg. 2005 Jan; 129(1):228-30. Carter YM, Shagrun L, Klein H, Katz J, Jablons DM. PMID: 15632855.
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    193. Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun. 2004 Oct 29; 323(4):1246-50. Lee AY, He B, You L, Xu Z, Mazieres J, Reguart N, Mikami I, Batra S, Jablons DM. PMID: 15451431.
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    194. Cloning and characterization of the promoter of human Wnt inhibitory factor-1. Biochem Biophys Res Commun. 2004 Oct 08; 323(1):229-34. Reguart N, He B, Xu Z, You L, Lee AY, Mazieres J, Mikami I, Batra S, Rosell R, McCormick F, Jablons DM. PMID: 15351726.
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    195. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene. 2004 Aug 26; 23(39):6672-6. Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM. PMID: 15221014.
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    196. Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene. 2004 Aug 12; 23(36):6170-4. You L, He B, Xu Z, Uematsu K, Mazieres J, Mikami I, Reguart N, Moody TW, Kitajewski J, McCormick F, Jablons DM. PMID: 15208662.
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    197. Interleukin-4 receptor cytotoxin as therapy for human malignant pleural mesothelioma xenografts. Ann Thorac Surg. 2004 Aug; 78(2):436-43; discussion 436-43. Beseth BD, Cameron RB, Leland P, You L, Varricchio F, Kreitman RJ, Maki RA, Jablons DM, Husain SR, Puri RK. PMID: 15276492.
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    198. An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res. 2004 Aug 01; 64(15):5385-9. You L, He B, Xu Z, Uematsu K, Mazieres J, Fujii N, Mikami I, Reguart N, McIntosh JK, Kashani-Sabet M, McCormick F, Jablons DM. PMID: 15289346.
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    199. Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res. 2004 Jul 15; 64(14):4717-20. Mazieres J, He B, You L, Xu Z, Lee AY, Mikami I, Reguart N, Rosell R, McCormick F, Jablons DM. PMID: 15256437.
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    200. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol. 2004 Jun 01; 22(11):2184-91. Johnson DH, Fehrenbacher L, Novotny WF, Herbst RS, Nemunaitis JJ, Jablons DM, Langer CJ, DeVore RF, Gaudreault J, Damico LA, Holmgren E, Kabbinavar F. PMID: 15169807.
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    201. Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells. Cancer Res. 2004 May 15; 64(10):3474-8. You L, He B, Uematsu K, Xu Z, Mazieres J, Lee A, McCormick F, Jablons DM. PMID: 15150100.
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    202. Activity of the suppressor of cytokine signaling-3 promoter in human non-small-cell lung cancer. Clin Lung Cancer. 2004 May; 5(6):366-70. He B, You L, Xu Z, Mazieres J, Lee AY, Jablons DM. PMID: 15217536.
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    203. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer. J Natl Cancer Inst. 2004 Feb 18; 96(4):326-31. Nemunaitis J, Sterman D, Jablons D, Smith JW, Fox B, Maples P, Hamilton S, Borellini F, Lin A, Morali S, Hege K. PMID: 14970281.
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    204. Isolated pulmonary arteriovenous malformations requiring anatomic resection. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):574-6. Mann MJ, Kramer MJ, Hall TS, Anastassiou P, Katz J, Golden J, Jones K, Jablons DM. PMID: 14762372.
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    205. Future directions: oncolytic viruses. Clin Lung Cancer. 2004 Jan; 5(4):226-30. You L, He B, Xu Z, McCormick F, Jablons DM. PMID: 14967074.
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    206. Retrocardiac parathyroid tumor: a rare mediastinal site. Surgery. 2004 Jan; 135(1):104-7. Corvera CU, Jablons D, Morita E, Clark OH. PMID: 14694307.
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    207. Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET. Radiographics. 2004 Jan-Feb; 24(1):105-19. Wang ZJ, Reddy GP, Gotway MB, Higgins CB, Jablons DM, Ramaswamy M, Hawkins RA, Webb WR. PMID: 14730040.
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    208. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. Neoplasia. 2004 Jan-Feb; 6(1):7-14. He B, You L, Uematsu K, Xu Z, Lee AY, Matsangou M, McCormick F, Jablons DM. PMID: 15068666.
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    209. Mechanisms of and potential treatment strategies for metastatic disease in non-small cell lung cancer. Semin Thorac Cardiovasc Surg. 2004; 16(1):40-50. Maslyar DJ, Jahan TM, Jablons DM. PMID: 15366686.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    210. SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14133-8. He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM. PMID: 14617776.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    211. Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression. Oncogene. 2003 Oct 16; 22(46):7218-21. Uematsu K, He B, You L, Xu Z, McCormick F, Jablons DM. PMID: 14562050.
      View in: PubMed   Mentions: 114     Fields:    Translation:Humans
    212. Potential of mobile intraoperative radiotherapy technology. Surg Oncol Clin N Am. 2003 Oct; 12(4):943-54. Goer DA, Musslewhite CW, Jablons DM. PMID: 14989125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    213. Intraoperative radiation therapy in the multimodality approach to upper aerodigestive tract cancer. Surg Oncol Clin N Am. 2003 Oct; 12(4):1043-63. Carter YM, Jablons DM, DuBois JB, Thomas CR. PMID: 14989132.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    214. Integrin alphavbeta8-mediated activation of transforming growth factor-beta inhibits human airway epithelial proliferation in intact bronchial tissue. Am J Pathol. 2003 Aug; 163(2):533-42. Fjellbirkeland L, Cambier S, Broaddus VC, Hill A, Brunetta P, Dolganov G, Jablons D, Nishimura SL. PMID: 12875973.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    215. c-Kit is not expressed in malignant mesothelioma. Mod Pathol. 2003 Aug; 16(8):818-22. Horvai AE, Li L, Xu Z, Kramer MJ, Jablons DM, Treseler PA. PMID: 12920227.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    216. 1st International Lung Cancer Conference in Beijing, October 27-30, 2002. Lung Cancer. 2003 Aug; 41(2):237-44. Jablons DM, Cheng SJ, Carolyn Clary-Macy RN, Hirsch FR. PMID: 12871790.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    217. Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin. Cancer Res. 2003 Aug 01; 63(15):4547-51. Uematsu K, Kanazawa S, You L, He B, Xu Z, Li K, Peterlin BM, McCormick F, Jablons DM. PMID: 12907630.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    218. Genomic alterations in human mesothelioma including high resolution mapping of common regions of DNA loss in chromosome arm 6q. Anticancer Res. 2003 May-Jun; 23(3B):2281-9. Jensen RH, Tiirikainen M, You L, Ginzinger D, He B, Uematsu K, Xu Z, Treseler P, McCormick F, Jablons DM. PMID: 12894504.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    219. Malignant mesothelioma does not demonstrate overexpression or gene amplification despite cytoplasmic immunohistochemical staining for c-Erb-B2. Arch Pathol Lab Med. 2003 Apr; 127(4):465-9. Horvai AE, Li L, Xu Z, Kramer MJ, Jablons DM, Treseler PA. PMID: 12683876.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    220. Cloning and characterization of a functional promoter of the human SOCS-3 gene. Biochem Biophys Res Commun. 2003 Feb 07; 301(2):386-91. He B, You L, Uematsu K, Matsangou M, Xu Z, He M, McCormick F, Jablons DM. PMID: 12565872.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    221. Pericardial retraction sutures facilitate intrapericardial pneumonectomy. J Cardiovasc Surg (Torino). 2003 Feb; 44(1):141-2. Brevetti GR, Lin SC, Jablons DM, Napierkowski MT, Brevetti LS, Hall TS. PMID: 12627088.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    222. Matrix metalloproteinase expression in lung cancer. Methods Mol Med. 2003; 74:349-56. Lim M, Jablons DM. PMID: 12415707.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    223. A comparison analysis of anti-tumor efficacy of adenoviral gene replacement therapy (p14ARF and p16INK4A) in human mesothelioma cells. Anticancer Res. 2003 Jan-Feb; 23(1A):33-8. Yang CT, You L, Lin YC, Lin CL, Mccormick F, Jablons DM. PMID: 12680192.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    224. Emergent surgery for massive pulmonary embolism on the basis of clinical diagnosis. Tex Heart Inst J. 2003; 30(2):149-51. Brevetti GR, O'Brien B, Coomer CL, Hall TS, Brevetti LS, Jablons DM. PMID: 12809261.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    225. Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2002 Dec; 124(6):1183-9. Lee TT, Everett DL, Shu HK, Jahan TM, Roach M, Speight JL, Cameron RB, Phillips TL, Chan A, Jablons DM. PMID: 12447185.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    226. Contralateral tension pneumothorax during one-lung ventilation for lobectomy: diagnosis aided by fiberoptic bronchoscopy. Anesth Analg. 2002 Sep; 95(3):570-2, table of contents. Malik S, Shapiro WA, Jablons D, Katz JA. PMID: 12198039.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    227. Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res. 2002 Jul 01; 62(13):3636-40. Massion PP, Kuo WL, Stokoe D, Olshen AB, Treseler PA, Chin K, Chen C, Polikoff D, Jain AN, Pinkel D, Albertson DG, Jablons DM, Gray JW. PMID: 12097266.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    228. Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides. . 2002 Jul; 1(9):687-94. Xia C, Xu Z, Yuan X, Uematsu K, You L, Li K, Li L, McCormick F, Jablons DM. PMID: 12479365.
      View in: PubMed   Mentions:
    229. Aberrations in the fragile histidine triad (FHIT) gene in idiopathic pulmonary fibrosis. Cancer Res. 2001 Dec 01; 61(23):8527-33. Uematsu K, Yoshimura A, Gemma A, Mochimaru H, Hosoya Y, Kunugi S, Matsuda K, Seike M, Kurimoto F, Takenaka K, Koizumi K, Fukuda Y, Tanaka S, Chin K, Jablons DM, Kudoh S. PMID: 11731438.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    230. p14(ARF) modulates the cytolytic effect of ONYX-015 in mesothelioma cells with wild-type p53. Cancer Res. 2001 Aug 15; 61(16):5959-63. Yang CT, You L, Uematsu K, Yeh CC, McCormick F, Jablons DM. PMID: 11507034.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    231. The impact of changes in radiographic abnormalities in organ donors on successful lung donation. J Heart Lung Transplant. 2001 Feb; 20(2):242-243. McCowin M, Hall TS, Babcock W, Solinger LL, Hall KW, Jablons D. PMID: 11250475.
      View in: PubMed   Mentions:    Fields:    
    232. Prostaglandin E2 and vasoactive intestinal peptide increase vascular endothelial cell growth factor mRNAs in lung cancer cells. Lung Cancer. 2001 Feb-Mar; 31(2-3):203-12. Casibang M, Purdom S, Jakowlew S, Neckers L, Zia F, Ben-Av P, Hla T, You L, Jablons DM, Moody TW. PMID: 11165399.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    233. Stage II (N1) lung cancer. Chest Surg Clin N Am. 2001 Feb; 11(1):39-59, viii. Choy O, Jahan T, Roach M, You L, Jablons D. PMID: 11253600.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    234. Expression sequence tag-specific full-length cDNA cloning: actin cDNAs. Gene. 2001 Jan 24; 263(1-2):265-72. Xu Z, Jablons DM, Gruenert DC. PMID: 11223266.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    235. Giant tumors of the chest: preoperative embolization and resection. J Cardiovasc Surg (Torino). 2000 Dec; 41(6):945-52. Brevetti GR, Sasse KC, Khan JH, Wilson MW, Clary-Macy C, Brevetti LS, Hall TS, Jablons D. PMID: 11232982.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    236. Positron emission tomography with f18-fluorodeoxyglucose in the staging and preoperative evaluation of malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2000 Jul; 120(1):128-33. Schneider DB, Clary-Macy C, Challa S, Sasse KC, Merrick SH, Hawkins R, Caputo G, Jablons D. PMID: 10884665.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    237. Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells. J Natl Cancer Inst. 2000 Apr 19; 92(8):636-41. Yang CT, You L, Yeh CC, Chang JW, Zhang F, McCormick F, Jablons DM. PMID: 10772681.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    238. ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients. Cancer Res. 2000 Feb 15; 60(4):1009-13. You L, Yang CT, Jablons DM. PMID: 10706117.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    239. Pulmonary placental transmogrification: diagnosis and treatment. J Thorac Cardiovasc Surg. 1999 Nov; 118(5):966-7. Brevetti GR, Clary-Macy C, Jablons DM. PMID: 10534710.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    240. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett. 1998 Dec 11; 441(1):88-92. Lim M, Martinez T, Jablons D, Cameron R, Guo H, Toole B, Li JD, Basbaum C. PMID: 9877171.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    241. Giant solitary fibrous tumor of the pleura. Ann Thorac Surg. 1998 May; 65(5):1461-4. Khan JH, Rahman SB, Clary-Macy C, Kerlan RK, George TI, Hall TS, Jablons DM. PMID: 9594894.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    242. Resection and IORT followed by three-dimensional conformal radiotherapy with or without adjuvant chemotherapy for malignant mesothelioma. Front Radiat Ther Oncol. 1997; 31:140-5. Jablons DM, Roach M, Jahan T, Cameron RB. PMID: 9263808.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    243. The heimlich device in thoracic surgery. Surg Technol Int. 1997; 6:91-5. Key SP, Cameron RC, Jablons DM. PMID: 16160960.
      View in: PubMed   Mentions:    Fields:    
    244. Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia. Cancer Res. 1992 Aug 01; 52(15):4113-6. Greenberg AS, Nordan RP, McIntosh J, Calvo JC, Scow RO, Jablons D. PMID: 1638523.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    245. Interleukin-3 induces proliferation but not lymphokine activated killer activity from human and murine mononuclear cells. Eur Cytokine Netw. 1990 May-Jun; 1(2):91-8. Jablons DM, Donohue R, Kawakami Y, Young JD, Lotze MT. PMID: 2102814.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    246. IL-2-based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis. J Immunol. 1990 May 01; 144(9):3630-6. Jablons D, Bolton E, Mertins S, Rubin M, Pizzo P, Rosenberg SA, Lotze MT. PMID: 2158514.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    247. Antitumor activity of recombinant interleukin 6 in mice. J Exp Med. 1990 Mar 01; 171(3):629-36. Mulé JJ, McIntosh JK, Jablons DM, Rosenberg SA. PMID: 2307930.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    248. In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice. J Immunol. 1989 Jul 01; 143(1):162-7. McIntosh JK, Jablons DM, Mulé JJ, Nordan RP, Rudikoff S, Lotze MT, Rosenberg SA. PMID: 2499626.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    249. Metastasectomy for soft tissue sarcoma. Further evidence for efficacy and prognostic indicators. J Thorac Cardiovasc Surg. 1989 May; 97(5):695-705. Jablons D, Steinberg SM, Roth J, Pittaluga S, Rosenberg SA, Pass HI. PMID: 2709861.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    250. IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans. J Immunol. 1989 Mar 01; 142(5):1542-7. Jablons DM, Mulé JJ, McIntosh JK, Sehgal PB, May LT, Huang CM, Rosenberg SA, Lotze MT. PMID: 2783945.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    251. Induction of interferon-beta 2/interleukin-6 (IL-6) by cytokine administration and detection of circulating interleukin-6 in the tumor-bearing state. Ann N Y Acad Sci. 1989; 557:157-60; discussion 160-1. Jablons DM, McIntosh JK, Mulé JJ, Nordan RP, Rudikoff S, Lotze MT. PMID: 2472087.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    252. Derivation of cells with lytic activity against fresh and cultured tumors from human bone marrow. J Surg Res. 1988 Apr; 44(4):404-16. Jablons DM, Lotze MT. PMID: 3258943.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
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