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Synergistic Treatment of Prostate Cancer and Multiple Myeloma using CD46-Targeted Radioimmunotherapy Antibody-Drug Conjugates. Clin Cancer Res. 2026 Apr 15; 32(8):1540-1556.
Bidkar AP, Bidlingmaier S, Wadhwa A, Mayne E, Raveendran A, Naik S, Xue C, Basak M, Bobba KN, Patiño-Escobar B, Greenland N, Camara Serrano JA, Steri V, Chou J, Wiita A, He J, Wilson DM, Aggarwal R, VanBrocklin HF, Seo Y, Liu B, Flavell RR. PMID: 41569419; PMCID: PMC13080322.
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HumansAnimalsCells
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Regioselective Glycosylation of Fluorine-18-Labeled Sorbitol for Enhanced Bacterial Detection In Vivo Using PET. JACS Au. 2025 Dec 22; 5(12):6189-6199.
Lee SH, Kim JM, López-Álvarez M, Sorlin AM, Bhat MY, Blecha J, Flavell RR, Seo Y, Engel J, Ohliger M, Wilson DM. PMID: 41450663; PMCID: PMC12728616.
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Selective treatment of acute myeloid leukemia targeting the activated conformation of integrin beta2 with [225Ac]Macropa-PEG4-7065. Nuclear Medicine and Biology. 2025 Nov 1; 150:109544.
Wadhwa WA, Johnson JH, Mandal MK, Bobba BK, Bidkar BA, Raveendran RA, Mayne ME, Rampersaud RS, Kang KA, Basak BM, Lopez-Alvarez LM, Lee LS, Steri SV, Wilson WD, VanBrocklin VH, Seo SY, Adams AJ, Sidhu SS, Wiita WA, Flavell FR. .
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Development of [18F]RP115 for clinical imaging of EAAT2 in neurodegenerative diseases. Nuclear Medicine and Biology. 2025 Nov 1; 150:109434.
Teixeira TR, Latter LM, Tapper TS, O'Sullivan OM, Gerdes GJ, Forsayeth FJ, Chao CC, Wilson WD, Ippisch IR, Castillo CJ, Beck BS, VanBrocklin VH, Blecha BJ. .
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Development of 18F-labelled Zinc Biosensors and PET Imaging. Nuclear Medicine and Biology. 2025 Sep 1; 148:109082.
Ali AU, Mu MC, Blecha BJ, Wadhwa WA, Meher MN, Bidkar BA, Wang WS, Seo SY, Wilson WD, VanBrocklin VH, Flavell FR. .
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Evaluation of 134Ce/134La-PSMA-617 for PET Imaging and Auger Electron Therapy of Prostate Cancer. J Nucl Med. 2025 08 01; 66(8):1252-1257.
Bobba KN, Wadhwa A, Bidkar AP, Raveendran A, Garcia L, Greenland N, Wilson DM, Seo Y, VanBrocklin HF, Flavell RR. PMID: 40506238; PMCID: PMC12320565.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy. Clin Cancer Res. 2025 Jul 15; 31(14):2963-2977.
Bidkar AP, Peter R, Wadhwa A, Bobba KN, Bidlingmaier S, Meher N, Chou J, Greenland N, Dasari C, Naik S, Raveendran A, Basak M, Camara Serrano JA, Steri V, Kogan S, Oskowitz A, He J, Wilson DM, Aggarwal R, Sriram R, VanBrocklin HF, Seo Y, Liu B, Flavell RR. PMID: 39945595; PMCID: PMC12260511.
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HumansAnimalsCells
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Deuterium Metabolic Imaging of the Brain Using 2-Deoxy-2-[2H2]-d-glucose: A Non-ionizing [18F]FDG Alternative. JACS Au. 2025 Feb 24; 5(2):571-577.
Gao X, Qiao K, Wilson DM, Chaumeil MM, Gordon JW. PMID: 40017751; PMCID: PMC11862922.
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1
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First-in-human healthy volunteer dosimetry studies of the excitatory amino acid transporter 2 (EAAT2) PET imaging tracer methyl N4-(7-[18F]fluoro-9H-fluoren-2-yl)asparaginate, [18F]RP-115. Nucl Med Biol. 2025 Mar-Apr; 142-143:108992.
Chao CK, Blecha J, Polvoy I, Nillo RM, Seo Y, Wilson DM, Forsayeth JR, VanBrocklin HF, Gerdes JM. PMID: 39913962; PMCID: PMC13170702.
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1 Fields:
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Humans
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PET Imaging Using 89Zr-Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention in Prostate Cancer. Mol Cancer Ther. 2025 Jan 02; 24(1):141-151.
Meher N, Bidkar AP, Wadhwa A, Bobba KN, Dhrona S, Dasari C, Mu C, Fong COY, Cámara JA, Ali U, Basak M, Bulkley D, Steri V, Fontaine SD, Zhu J, Oskowitz A, Aggarwal RR, Sriram R, Chou J, Wilson DM, Seo Y, Santi DV, Ashley GW, VanBrocklin HF, Flavell RR. PMID: 39331510; PMCID: PMC11694059.
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PubMed Mentions:
6 Fields:
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HumansAnimalsCells
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Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumors. STAR Protoc. 2024 09 20; 5(3):103091.
Mu C, Liu X, Riselli A, Slater J, Escobar E, Dang D, Drapeau S, Delos Santos R, Andosca S, Nguyen H, Larson PEZ, Bok R, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 38943645; PMCID: PMC11261128.
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PubMed Mentions:
1 Fields:
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HumansAnimals
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Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography. ACS Infect Dis. 2024 06 14; 10(6):2108-2117.
Pandey A, Chopra S, Cleary SJ, López-Álvarez M, Quimby FM, Alanizi AAA, Sakhamuri S, Zhang N, Looney MR, Craik CS, Wilson DM, Evans MJ. PMID: 38819300.
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2 Fields:
Translation:
Animals
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Prostate-Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate Cancer. Adv Healthc Mater. 2024 07; 13(19):e2304618.
Meher N, Ashley GW, Bobba KN, Wadhwa A, Bidkar AP, Dasari C, Mu C, Sankaranarayanan RA, Serrano JAC, Raveendran A, Bulkley DP, Aggarwal R, Greenland NY, Oskowitz A, Wilson DM, Seo Y, Santi DV, VanBrocklin HF, Flavell RR. PMID: 38700450; PMCID: PMC11281871.
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HumansAnimalsCells
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Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO. Bioconjug Chem. 2024 04 17; 35(4):517-527.
Alanizi AA, Sorlin AM, Parker MFL, López-Álvarez M, Qin H, Lee SH, Blecha J, Rosenberg OS, Engel J, Ohliger MA, Flavell RR, Wilson DM. PMID: 38482815; PMCID: PMC11036355.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection. JACS Au. 2024 Mar 25; 4(3):1039-1047.
Sorlin AM, López-Álvarez M, Biboy J, Gray J, Rabbitt SJ, Rahim JU, Lee SH, Bobba KN, Blecha J, Parker MFL, Flavell RR, Engel J, Ohliger M, Vollmer W, Wilson DM. PMID: 38559735; PMCID: PMC10976610.
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4
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P-045 First in-human studies of the glutamate transporter EAAT2 radiotracer methyl N4-(7-[18F]fluoro-9H-fluoren-2-yl)asparginate (RP-115): radiosynthesis and biodistribution evaluation. Nuclear Medicine and Biology. 2023 Nov 1; 126:108517.
Nillo NR, Blecha BJ, Chao CC, Seo SY, Forsayeth FJ, Gerdes GJ, VanBrocklin VH, Wilson WD. .
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O-14 Evaluation of 134Ce/La pair as a PET imaging surrogate for 225Ac radiotherapeutics. Nuclear Medicine and Biology. 2023 Nov 1; 126:108410.
Bobba BK, Bidkar BA, Meher MN, Fong FC, Wadhwa WA, Dhrona DS, Sorlin SA, Bidlingmaier BS, Shuere SB, He HJ, Wilson WD, Liu LB, Seo SY, VanBrocklin VH, Flavell FR. .
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O-04 StarPEG Nanocarriers for PSMA Targeted Radioligand Imaging and Therapy. Nuclear Medicine and Biology. 2023 Nov 1; 126:108400.
Bidkar BA, Meher MN, Ashley AG, Wadhwa WA, Bobba BK, Shuere SB, Wilson WD, Seo SY, Santi SD, VanBrocklin VH, Flavell FR. .
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The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection. J Nucl Med. 2023 11; 64(11):1676-1682.
Signore A, Ordonez AA, Arjun C, Aulakh GK, Beziere N, Dadachova E, Ebenhan T, Granados U, Korde A, Jalilian A, Lestari W, Mukherjee A, Petrik M, Sakr T, Cuevas CLS, Welling MM, Zeevaart JR, Jain SK, Wilson DM. PMID: 37770110; PMCID: PMC10626374.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma. J Nucl Med. 2023 01; 64(1):137-144.
Shin J, Parker MFL, Zhu I, Alanizi A, Rodriguez CI, Liu R, Watchmaker PB, Kalita M, Blecha J, Luu J, Wright B, Lapi SE, Flavell RR, Okada H, Tlsty TD, Roybal KT, Wilson DM. PMID: 35981900; PMCID: PMC9841254.
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5 Fields:
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HumansAnimalsCells
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Nuclear imaging of bacterial infection: the state of the art and future directions. Chinese Journal of Nuclear Medicine and Molecular Imaging. 2022 Jul 25; 42(07):436-444.
Polvoy PI, Flavell FR, Rosenberg RO, Ohliger OM, Wilson WD. .
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Imaging joint infections using D-methyl-11C-methionine PET/MRI: initial experience in humans. Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3761-3771.
Polvoy I, Seo Y, Parker M, Stewart M, Siddiqua K, Manacsa HS, Ravanfar V, Blecha J, Hope TA, Vanbrocklin H, Flavell RR, Barry J, Hansen E, Villanueva-Meyer JE, Engel J, Rosenberg OS, Wilson DM, Ohliger MA. PMID: 35732972; PMCID: PMC9399217.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET. ACS Central Science. 2021 Sep 2.
Zhao ZN, Bardine BC, Lourenc¸o LA, Wang WY, Huang HY, Cleary CS, Wilson WD, Oh OD, Fong FL, Looney LM, Evans EM, Craik CC. .
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Deuterium Metabolic Imaging—Rediscovery of a Spectroscopic Tool. Metabolites. 2021 Aug 25; 11(9):570.
Polvoy PI, Qin QH, Flavell FR, Gordon GJ, Viswanath VP, Sriram SR, Ohliger OM, Wilson WD. .
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Synthesis of N-trifluoromethyl amides from carboxylic acids. Chem. 2021 Aug 1; 7(8):2245-2255.
Liu LJ, Parker PM, Wang WS, Flavell FR, Toste TF, Wilson WD. .
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Cyclic 68Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2. J Nucl Med. 2021 Nov; 62(11):1631-1637.
Parker MFL, Blecha J, Rosenberg O, Ohliger M, Flavell RR, Wilson DM. PMID: 33637588; PMCID: PMC8612341.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Nuclear Imaging of Bacterial Infection: The State of the Art and Future Directions. J Nucl Med. 2020 12; 61(12):1708-1716.
Polvoy I, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32764120; PMCID: PMC9364899.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimals
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Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. Sci Rep. 2018 05 21; 8(1):7928.
Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM. PMID: 29786697; PMCID: PMC5962598.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Clinical Utility of Diffusion-Weighted Imaging in Spinal Infections. Clin Neuroradiol. 2019 Sep; 29(3):515-522.
Dumont RA, Keen NN, Bloomer CW, Schwartz BS, Talbott J, Clark AJ, Wilson DM, Chin CT. PMID: 29582111; PMCID: PMC6158113.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Introduction: MRI/MRS as Metabolic Imaging Tools. Imaging and Metabolism. 2018 Jan 1; 81-98.
Wilson WD, Ohliger OM. .
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Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers. Sci Rep. 2017 08 11; 7(1):7903.
Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 28801560; PMCID: PMC5554133.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Exploring Metabolism In Vivo Using Endogenous 11C Metabolic Tracers. Semin Nucl Med. 2017 09; 47(5):461-473.
Neumann K, Flavell R, Wilson DM. PMID: 28826521; PMCID: PMC6037183.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Bacterial Imaging. Imaging Infections. 2017 Jan 1; 149-172.
Ordonez OA, Bambarger BL, Murthy MN, Wilson WD, Jain JS. .
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A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography. Chem Sci. 2016 Aug 01; 7(8):5503-5507.
Liu W, Truillet C, Flavell RR, Brewer TF, Evans MJ, Wilson DM, Chang CJ. PMID: 30034690; PMCID: PMC6021783.
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13
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Recent Developments in Combined PET/MRI. Current Radiology Reports. 2016 May 1; 4(5):22.
Flavell FR, Wilson WD, Behr BS. .
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[(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography. Chem Commun (Camb). 2016 Apr 07; 52(27):4888-90.
Carroll VN, Truillet C, Shen B, Flavell RR, Shao X, Evans MJ, VanBrocklin HF, Scott PJ, Chin FT, Wilson DM. PMID: 26963495; PMCID: PMC4854297.
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PubMed Mentions:
28 Fields:
Translation:
Cells
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Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging. Chem Commun (Camb). 2016 Feb 18; 52(14):3030-3.
Korenchan DE, Flavell RR, Baligand C, Sriram R, Neumann K, Sukumar S, VanBrocklin H, Vigneron DB, Wilson DM, Kurhanewicz J. PMID: 26792559; PMCID: PMC4864526.
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PubMed Mentions:
25 Fields:
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Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI. Chem Commun (Camb). 2015 Sep 25; 51(74):14119-22.
Flavell RR, von Morze C, Blecha JE, Korenchan DE, Van Criekinge M, Sriram R, Gordon JW, Chen HY, Subramaniam S, Bok RA, Wang ZJ, Vigneron DB, Larson PE, Kurhanewicz J, Wilson DM. PMID: 26257040; PMCID: PMC4854286.
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PubMed Mentions:
25 Fields:
Translation:
Cells
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Abstract B37: Patient-derived tissue culture model systems of renal cell carcinoma for development of clinically translatable metabolic biomarkers. Preclinical Studies. 2014 Nov 1; b37-b37.
Sriram SR, Keshari KK, Criekinge CM, Kurhanewicz KJ, Wilson WD, Peehl PD, Bok BR, Zhen ZW. .
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ChemInform Abstract: Chemistry and Biochemistry of 13C Hyperpolarized Magnetic Resonance Using Dynamic Nuclear Polarization. ChemInform. 2014 May 6; 45(18):no-no.
Keshari KK, Wilson WD. .
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Case report: glioblastoma multiforme complicating familial cavernous malformations. Clin Neuroradiol. 2014 Sep; 24(3):293-6.
Wilson DM, Cohen B, Keshari K, Vogel H, Steinberg G, Dillon W. PMID: 23942770.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Solid phase synthesis of hydroxamate peptides for histone deacetylase inhibition. Tetrahedron Letters. 2013 Jan 1; 54(2):151-153.
Wilson WD, Silverman SL, Bergauer BM, Keshari KK. .
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Metabolic Profiling of CNS Lymphoma and Its Microenvironment. Blood. 2011 Nov 18; 118(21):588-588.
Bet-Lachin BA, Jiang JF, Chen CL, Keshari KK, Wilson WD, Kurhanewicz KJ, Rubenstein RJ. .
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Cyclodextrin dimers as cleavable carriers of photodynamic sensitizers. J Am Chem Soc. 2001 Dec 19; 123(50):12488-94.
Baugh SD, Yang Z, Leung DK, Wilson DM, Breslow R. PMID: 11741411.
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PubMed Mentions:
18 Fields:
Translation:
Cells