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Dennis Nielson, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentPediatrics
Address550 16th. Street
San Francisco CA 94158
Phone415-476-3471
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine
    University of UtahM.D.1976School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Small-Molecule Therapies for CF
    NIH/NIDDK P30DK072517Sep 15, 2005 - May 31, 2020
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Phuan PW, Son JH, Tan JA, Li C, Musante I, Zlock L, Nielson D, Finkbeiner WE, Kurth MJ, Galietta LJ, Haggie PM, Verkman AS. Combination potentiator ('co-potentiator') therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators. J Cyst Fibros. 2018 Jun 11. PMID: 29903467.
      View in: PubMed
    2. McGarry ME, Neuhaus JM, Nielson D, Burchard E, Ly NP. Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis. Pediatr Pulmonol. 2017 Dec; 52(12):1550-1557. PMID: 29082671.
      View in: PubMed
    3. McGarry ME, Illek B, Ly NP, Zlock L, Olshansky S, Moreno C, Finkbeiner WE, Nielson D. In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies. Pediatr Pulmonol. 2017 Apr; 52(4):472-479. PMID: 28068001.
      View in: PubMed
    4. Haggie PM, Phuan PW, Tan JA, Xu H, Avramescu RG, Perdomo D, Zlock L, Nielson D, Finkbeiner WE, Lukacs GL, Verkman AS. Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product. J Biol Chem. 2017 01 20; 292(3):771-785. PMID: 27895116.
      View in: PubMed
    5. Okumura MJ, Ong T, Dawson D, Nielson D, Lewis N, Richards M, Brindis CD, Kleinhenz ME. Improving transition from paediatric to adult cystic fibrosis care: programme implementation and evaluation. BMJ Qual Saf. 2014 Apr; 23 Suppl 1:i64-i72. PMID: 24415776.
      View in: PubMed
    6. McGarry ME, Nielson D. Normalization of sweat chloride concentration and clinical improvement with ivacaftor in a patient with cystic fibrosis with mutation S549N. Chest. 2013 Oct; 144(4):e1-e4. PMID: 24081349; PMCID: PMC4502741.
    7. Prach L, Koepke R, Kharrazi M, Keiles S, Salinas DB, Reyes MC, Pian M, Opsimos H, Otsuka KN, Hardy KA, Milla CE, Zirbes JM, Chipps B, O'Bra S, Saeed MM, Sudhakar R, Lehto S, Nielson D, Shay GF, Seastrand M, Jhawar S, Nickerson B, Landon C, Thompson A, Nussbaum E, Chin T, Wojtczak H. Novel CFTR variants identified during the first 3 years of cystic fibrosis newborn screening in California. J Mol Diagn. 2013 Sep; 15(5):710-22. PMID: 23810505.
      View in: PubMed
    8. Gibb E, Blount R, Lewis N, Nielson D, Church G, Jones K, Ly N. Management of plastic bronchitis with topical tissue-type plasminogen activator. Pediatrics. 2012 Aug; 130(2):e446-50. PMID: 22802609.
      View in: PubMed
    9. Paul IM, Maselli JH, Hersh AL, Boushey HA, Nielson D, Cabana MD. Antibiotic prescribing during pediatric ambulatory care visits for asthma. Pediatrics. 2011 Jun; 127(6):1014-21. PMID: 21606155.
      View in: PubMed
    10. Cox MJ, Allgaier M, Taylor B, Baek MS, Huang YJ, Daly RA, Karaoz U, Andersen GL, Brown R, Fujimura KE, Wu B, Tran D, Koff J, Kleinhenz ME, Nielson D, Brodie EL, Lynch SV. Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients. PLoS One. 2010 Jun 23; 5(6):e11044. PMID: 20585638; PMCID: PMC2890402.
    11. Song Y, Namkung W, Nielson D, Lee JW, Finkbeiner WE, Verkman AS. Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function. Am J Physiol Lung Cell Mol Physiol. 2009 Dec; 297(6):L1131-40. PMID: 19820035.
      View in: PubMed
    12. Wu B, Nielson D. Should inhaled beta-agonists or lung function testing be routine in prematurely born infants with chronic lung disease? Pediatr Crit Care Med. 2008 Nov; 9(6):662-4. PMID: 18997602.
      View in: PubMed
    13. Schulz BL, Sloane AJ, Robinson LJ, Prasad SS, Lindner RA, Robinson M, Bye PT, Nielson D, Harry JL, Packer NH, Karlsson NG. Glycosylation of sputum mucins is altered in cystic fibrosis patients. Glycobiology. 2007 Jul; 17(7):698-712. PMID: 17392389.
      View in: PubMed
    14. Levin MH, Sullivan S, Nielson D, Yang B, Finkbeiner WE, Verkman AS. Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins. J Biol Chem. 2006 Sep 01; 281(35):25803-12. PMID: 16829520.
      View in: PubMed
    15. Song Y, Salinas D, Nielson D, Verkman AS. Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C741-9. PMID: 16207791.
      View in: PubMed
    16. Sloane AJ, Lindner RA, Prasad SS, Sebastian LT, Pedersen SK, Robinson M, Bye PT, Nielson D, Harry JL. Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects. Am J Respir Crit Care Med. 2005 Dec 01; 172(11):1416-26. PMID: 16166615.
      View in: PubMed
    17. Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson D, Verkman AS. Submucosal gland dysfunction as a primary defect in cystic fibrosis. FASEB J. 2005 Mar; 19(3):431-3. PMID: 15596485.
      View in: PubMed
    18. Alper OM, Wong LJ, Young S, Pearl M, Graham S, Sherwin J, Nussbaum E, Nielson D, Platzker A, Davies Z, Lieberthal A, Chin T, Shay G, Hardy K, Kharrazi M. Identification of novel and rare mutations in California Hispanic and African American cystic fibrosis patients. Hum Mutat. 2004 Oct; 24(4):353. PMID: 15365999.
      View in: PubMed
    19. Salinas DB, Pedemonte N, Muanprasat C, Finkbeiner WF, Nielson D, Verkman AS. CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor. Am J Physiol Lung Cell Mol Physiol. 2004 Nov; 287(5):L936-43. PMID: 15246976.
      View in: PubMed
    20. Yi MS, Britto MT, Wilmott RW, Kotagal UR, Eckman MH, Nielson D, Kociela VL, Tsevat J. Health values of adolescents with cystic fibrosis. J Pediatr. 2003 Feb; 142(2):133-40. PMID: 12584533.
      View in: PubMed
    21. Silvestri JM, Chen ML, Weese-Mayer DE, McQuitty JM, Carveth HJ, Nielson D, Borowitz D, Cerny F. Idiopathic congenital central hypoventilation syndrome: the next generation. Am J Med Genet. 2002 Sep 15; 112(1):46-50. PMID: 12239719.
      View in: PubMed
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