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Diane Wara, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentPediatrics
Address513 Parnassus Ave, Med Sci
San Francisco CA 94122
Phone415-476-2865
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine
    University of California IrvineM.D.1969School of Medicine

    Collapse Overview 
    Collapse Overview
    Diane Wara, MD, is a professor emeritus of pediatrics in the Allergy/Immunology Bone Marrow Transplant Division, director of the Northern California Pediatric HIV Program, and a member of the leadership group for the NIAID-funded domestic and international clinical trials program in HIV (IMPAACT). Her work, along with that of others, led to the successful strategy for the interruption of perinatal transmission in the developed world. Currently, she is working through IMPAACT to extend and modify successful strategies to prevent transmission throughout the developing world. Dr. Wara has authored more than180 publications and, throughout her career, has focused her research on the pathogenesis and treatment strategies of pediatric immune deficiency syndromes (PIDD) and pediatric HIV. She contributed to reports of the first child with adenosine deaminase deficiency as well as treatment strategies for this disorder, including the successful gene transfer in neonates with known ADA deficiency; the first child with purine nucleoside phosphorylase deficiency; the first child with ZAP-70 deficiency; and mutations in IKK -gamma leading to NEMO syndrome. Dr. Wara contributed to reports of the first child with HIV, the first subject to acquire HIV from a blood transfusion, the first report of vertical transmission of hepatitis C, the role(s) of genetic factors as well as neutralizing antibody in the perinatal transmission of HIV as well as long-term progression; the detection and diagnosis of in-utero versus peripartum transmission. She reported the successful interruption of HIV perinatal transmission by the use of intrapartum AZT to the mother and infant prophylaxis for 6 weeks; she reported numerous successful HIV treatment strategies for children and youth. Dr. Wara led the Immunology Division and the UCSF Pediatric Clinical Research Center for over 25 years. She served as member and chair of two NIH study sections as well as member and chair of the NIH Recombinant DNA Advisory Committee (2002-2006). Dr. Wara was elected to the National Academy of Sciences, Institute of Medicine, in 1998.


    Collapse Research 
    Collapse Research Activities and Funding
    BAY AREA PERINATAL AIDS CENTER
    NIH/NICHD P01HD024640Jan 1, 1989 - Mar 31, 1994
    Role: Principal Investigator
    BAY AREA PERINATAL AIDS COHORT STUDY
    NIH/NICHD R01HD024640Jan 1, 1989 - Dec 31, 1993
    Role: Principal Investigator
    Northern California Pediatrics AIDS Treatment Center
    NIH/NIAID U01AI027541Sep 30, 1988 - Feb 28, 2007
    Role: Principal Investigator
    IMMUNOLOGICAL SCIENCES STUDY SECTION
    NIH/CSR U09RG000003Jul 1, 1985 - Jun 30, 1992
    Role: Co-Principal Investigator
    PEDIATRIC CLINICAL RESEARCH CENTER
    NIH/NCRR M01RR001271Dec 1, 1981 - Mar 31, 2007
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

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    Collapse Global Health
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rutar T, Youm J, Porco T, Tilton N, Muskat M, McNamara N, Wara D. Ophthalmic manifestations of perinatally acquired HIV in a US cohort of long-term survivors. Br J Ophthalmol. 2015 May; 99(5):650-3. PMID: 25416182.
      View in: PubMed
    2. Thomas MR, Wara D, Saxton K, Truskier M, Chesney MA, Boyce WT. Family adversity and autonomic reactivity association with immune changes in HIV-affected school children. Psychosom Med. 2013 Jul-Aug; 75(6):557-65. PMID: 23766380; PMCID: PMC3830556.
    3. Wilson LS, Hensic L, Paoli CJ, Basu R, Christenson M, Moskowitz JT, Wara D. The effect of prophylaxis on pediatric HIV costs. AIDS Care. 2012; 24(1):108-18. PMID: 21780991; PMCID: PMC4201115.
    4. Ma CA, Wang HY, Temmerman S, Zhao Y, Wu L, Hornung RL, Wara D, Jain A. Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen-activated protein kinase activity. Hum Mutat. 2011 Mar; 32(3):318-24. PMID: 21309033.
      View in: PubMed
    5. Weinberg A, Song LY, Walker R, Allende M, Fenton T, Patterson-Bartlett J, Nachman S, Kemble G, Yi TT, Defechereux P, Wara D, Read JS, Levin M. Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children. J Acquir Immune Defic Syndr. 2010 Oct; 55(2):189-96. PMID: 20581690; PMCID: PMC3290334.
    6. Wilson LS, Basu R, Christenson M, Hensic L, Paoli C, Wara D, Moskowitz JT. Pediatric HIV costs across three treatment eras from 1986 to 2007. Pediatrics. 2010 Sep; 126(3):e541-9. PMID: 20696721.
      View in: PubMed
    7. Cheng LE, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara D. Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. Clin Immunol. 2009 Jul; 132(1):124-31. PMID: 19375390; PMCID: PMC2800791.
    8. Butensky James E, Harmatz P, Lee M, Kennedy C, Petru A, Wara D, Miaskowski C. Altered iron metabolism in children with human immunodeficiency virus disease. Pediatr Hematol Oncol. 2009 Mar; 26(2):69-84. PMID: 19322737.
      View in: PubMed
    9. Milojevic D, Nguyen KD, Wara D, Mellins ED. Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development. Pediatr Rheumatol Online J. 2008 Dec 01; 6:20. PMID: 19046457; PMCID: PMC2633304.
    10. Tremoulet AH, Capparelli EV, Patel P, Acosta EP, Luzuriaga K, Bryson Y, Wara D, Zorrilla C, Holland D, Mirochnick M. Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants. Antimicrob Agents Chemother. 2007 Dec; 51(12):4297-302. PMID: 17893155; PMCID: PMC2168008.
    11. Pahwa S, Muresan P, Sleasman J, Fenton T, Moye J, Deveikis A, Wara D, Van Dyke R. Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402. J Allergy Clin Immunol. 2007 Jun; 119(6):1538-41. PMID: 17418382.
      View in: PubMed
    12. Hecht JH, Glenn OA, Wara D, Wu YW. JC virus granule cell neuronopathy in a child with CD40 ligand deficiency. Pediatr Neurol. 2007 Mar; 36(3):186-9. PMID: 17352955.
      View in: PubMed
    13. Unadkat JD, Wara D, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE. Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother. 2007 Feb; 51(2):783-6. PMID: 17158945; PMCID: PMC1797783.
    14. Taylor Z, Butani L, Blumberg D, Cowan M, Wara D, Gopal S, Gavrilita C, Da-Silva S. Index of suspicion. Pediatr Rev. 2006 Dec; 27(12):463-9. PMID: 17142468.
      View in: PubMed
    15. Zhang H, Schaff UY, Green CE, Chen H, Sarantos MR, Hu Y, Wara D, Simon SI, Lowell CA. Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity. 2006 Aug; 25(2):285-95. PMID: 16901726; PMCID: PMC4698343.
    16. Weinberg A, Gona P, Nachman SA, Defechereux P, Yogev R, Hughes W, Wara D, Spector SA, Read J, Elgie C, Cooper M, Dankner W. Antibody responses to hepatitis A virus vaccine in HIV-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy. J Infect Dis. 2006 Jan 15; 193(2):302-11. PMID: 16362896.
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    17. Chan B, Wara D, Bastian J, Hershfield MS, Bohnsack J, Azen CG, Parkman R, Weinberg K, Kohn DB. Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID). Clin Immunol. 2005 Nov; 117(2):133-43. PMID: 16112907.
      View in: PubMed
    18. Cohan D, Feakins C, Wara D, Petru A, McNicholl I, Schillinger D, Lu J, Kuritzkes D, Deeks SG. Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen. AIDS. 2005 Jun 10; 19(9):989-90. PMID: 15905684.
      View in: PubMed
    19. von Scheven E, Lu TT, Emery HM, Elder ME, Wara D. Thrombosis and pediatric Wegener's granulomatosis: acquired and genetic risk factors for hypercoagulability. Arthritis Rheum. 2003 Dec 15; 49(6):862-5. PMID: 14673976.
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    20. Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara D, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, Graham BL, Spector SA. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol. 2003 Nov; 112(5):973-80. PMID: 14610491.
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    21. Lester P, Chesney M, Cooke M, Weiss R, Whalley P, Perez B, Glidden D, Petru A, Dorenbaum A, Wara D. When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children. J Acquir Immune Defic Syndr. 2002 Nov 01; 31(3):309-17. PMID: 12439206.
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    22. Bickel J, Wara D, Atkinson BF, Cohen LS, Dunn M, Hostler S, Johnson TR, Morahan P, Rubenstein AH, Sheldon GF, Stokes E. Increasing women's leadership in academic medicine: report of the AAMC Project Implementation Committee. Acad Med. 2002 Oct; 77(10):1043-61. PMID: 12377686.
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    23. Tuomala RE, Shapiro DE, Mofenson LM, Bryson Y, Culnane M, Hughes MD, O'Sullivan MJ, Scott G, Stek AM, Wara D, Bulterys M. Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N Engl J Med. 2002 Jun 13; 346(24):1863-70. PMID: 12063370.
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    24. Cunningham CK, Wara D, Kang M, Fenton T, Hawkins E, McNamara J, Mofenson L, Duliege AM, Francis D, McFarland EJ, Borkowsky W. Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women. Clin Infect Dis. 2001 Mar 01; 32(5):801-7. PMID: 11229849.
      View in: PubMed
    25. Morahan PS, Voytko ML, Abbuhl S, Means LJ, Wara D, Thorson J, Cotsonas CE. Ensuring the success of women faculty at AMCs: lessons learned from the National Centers of Excellence in Women's Health. Acad Med. 2001 Jan; 76(1):19-31. PMID: 11154189.
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    26. Zonana J, Elder ME, Schneider LC, Orlow SJ, Moss C, Golabi M, Shapira SK, Farndon PA, Wara D, Emmal SA, Ferguson BM. A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO). Am J Hum Genet. 2000 Dec; 67(6):1555-62. PMID: 11047757; PMCID: PMC1287930.
    27. Fahey JL, Aziz N, Spritzler J, Plaeger S, Nishanian P, Lathey JL, Seigel J, Landay AL, Kilarui R, Schmitz JL, White C, Wara D, Akridge R, Cutili J, Douglas SD, Reuben J, Shearer WT, Nokta M, Polland R, Schooley R, Asthana D, Mizrachi Y, Waxdal M. Need for an external proficiency testing program for cytokines, chemokines, and plasma markers of immune activation. Clin Diagn Lab Immunol. 2000 Jul; 7(4):540-8. PMID: 10882648; PMCID: PMC95910.
    28. Mirochnick M, Cooper E, McIntosh K, Xu J, Lindsey J, Jacobus D, Mofenson L, Sullivan JL, Dankner W, Frenkel LM, Nachman S, Wara D, Johnson D, Bonagura VR, Rathore MH, Cunningham CK, McNamara J. Pharmacokinetics of dapsone administered daily and weekly in human immunodeficiency virus-infected children. Antimicrob Agents Chemother. 1999 Nov; 43(11):2586-91. PMID: 10543733; PMCID: PMC89529.
    29. Seroogy CM, Wara D, Bluth MH, Dorenbaum A, White C, Durkin HG, Elder ME. Cytokine profile of a long-term pediatric HIV survivor with hyper-IgE syndrome and a normal CD4 T-cell count. J Allergy Clin Immunol. 1999 Nov; 104(5):1045-51. PMID: 10550751.
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    30. Wright PF, Lambert JS, Gorse GJ, Hsieh RH, McElrath MJ, Weinhold K, Wara D, Anderson EL, Keefer MC, Jackson S, Wagner LJ, Francis DP, Fast PE, McNamara J. Immunization with envelope MN rgp120 vaccine in human immunodeficiency virus-infected pregnant women. J Infect Dis. 1999 Oct; 180(4):1080-8. PMID: 10479134.
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    31. Wilfert C, Aronson JE, Beck DT, Fleischman AR, Kline MW, Mofenson LM, Scott GB, Wara D, Whitley-Williams PN. Planning for children whose parents are dying of HIV/AIDS. American Academy of Pediatrics. Committee on Pediatric AIDS, 1998-1999. Pediatrics. 1999 Feb; 103(2):509-11. PMID: 9925854.
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    32. McKinney RE, Johnson GM, Stanley K, Yong FH, Keller A, O'Donnell KJ, Brouwers P, Mitchell WG, Yogev R, Wara D, Wiznia A, Mofenson L, McNamara J, Spector SA. A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team. J Pediatr. 1998 Oct; 133(4):500-8. PMID: 9787687.
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    33. Williams GH, Wara D, Carbone P. Funding for patient-oriented research. Critical strain on a fundamental linchpin. JAMA. 1997 Jul 16; 278(3):227-31. PMID: 9218670.
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    34. Spector SA, Blanchard S, Wara D, Oleske JM, McIntosh K, Hodes D, Dankner WM, Salgo M, McNamara J. Comparative trial of two dosages of zalcitabine in zidovudine-experienced children with advanced human immunodeficiency virus disease. Pediatric AIDS Clinical Trials Group. Pediatr Infect Dis J. 1997 Jun; 16(6):623-6. PMID: 9194115.
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    35. Liang SW, Jemerin JM, Tschann JM, Wara D, Boyce WT. Life events, frontal electroencephalogram laterality, and functional immune status after acute psychological stressors in adolescents. Psychosom Med. 1997 Mar-Apr; 59(2):178-86. PMID: 9088055.
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    36. Englund JA, Baker CJ, Raskino C, McKinney RE, Lifschitz MH, Petrie B, Fowler MG, Connor JD, Mendez H, O'Donnell K, Wara D. Clinical and laboratory characteristics of a large cohort of symptomatic, human immunodeficiency virus-infected infants and children. AIDS Clinical Trials Group Protocol 152 Study Team. Pediatr Infect Dis J. 1996 Nov; 15(11):1025-36. PMID: 8933553.
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    37. Chou RH, Wong GB, Kramer JH, Wara D, Matthay KK, Crittenden MR, Swift PS, Cowan MJ, Wara WM. Toxicities of total-body irradiation for pediatric bone marrow transplantation. Int J Radiat Oncol Biol Phys. 1996 Mar 01; 34(4):843-51. PMID: 8598361.
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    38. Liang SW, Jemerin JM, Tschann JM, Irwin CE, Wara D, Boyce WT. Life events, cardiovascular reactivity, and risk behavior in adolescent boys. Pediatrics. 1995 Dec; 96(6):1101-5. PMID: 7491228.
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    39. Elder ME, Hope TJ, Parslow TG, Umetsu DT, Wara D, Cowan MJ. Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency. Cell Immunol. 1995 Oct 01; 165(1):110-7. PMID: 7671314.
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    40. Kliks SC, Wara D, Landers DV, Levy JA. Features of HIV-1 that could influence maternal-child transmission. JAMA. 1994 Aug 10; 272(6):467-74. PMID: 8040983.
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    41. Rautonen J, Rautonen N, Martin NL, Wara D. HIV type 1 Tat protein induces immunoglobulin and interleukin 6 synthesis by uninfected peripheral blood mononuclear cells. AIDS Res Hum Retroviruses. 1994 Jul; 10(7):781-5. PMID: 7986583.
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    42. Benkerrou M, Wara D, Elder M, Dror Y, Merino A, Colombe BW, Garovoy M, Cowan MJ. Anti-tetanus toxoid antibody production after mismatched T cell-depleted bone marrow transplantation. J Clin Immunol. 1994 Mar; 14(2):98-106. PMID: 8195318.
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    43. Wara D, Luzuriaga K, Martin NL, Sullivan JL, Bryson YJ. Maternal transmission and diagnosis of human immunodeficiency virus during infancy. Ann N Y Acad Sci. 1993 Oct 29; 693:14-9. PMID: 8267258.
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    44. Dror Y, Gallagher R, Wara D, Colombe BW, Merino A, Benkerrou M, Cowan MJ. Immune reconstitution in severe combined immunodeficiency disease after lectin-treated, T-cell-depleted haplocompatible bone marrow transplantation. Blood. 1993 Apr 15; 81(8):2021-30. PMID: 8471764.
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    45. Siller L, Martin NL, Kostuchenko P, Beckett L, Rautonen J, Cheng SC, Wara D. Serum levels of soluble CD8, neopterin, beta 2-microglobulin and p24 antigen as indicators of disease progression in children with AIDS on zidovudine therapy. AIDS. 1993 Mar; 7(3):369-73. PMID: 8097095.
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    46. Rautonen N, Martin NL, Rautonen J, Rooks Y, Mentzer WC, Wara D. Low number of antibody producing cells in patients with sickle cell anemia. Immunol Lett. 1992 Dec; 34(3):207-11. PMID: 1487307.
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    47. Bryson YJ, Luzuriaga K, Sullivan JL, Wara D. Proposed definitions for in utero versus intrapartum transmission of HIV-1. N Engl J Med. 1992 Oct 22; 327(17):1246-7. PMID: 1406816.
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    48. Rautonen J, Rautonen N, Martin NL, Philip R, Wara D. Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-alpha and immunoglobulin G and A concentrations in children with HIV infection. AIDS. 1991 Nov; 5(11):1319-25. PMID: 1768380.
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    49. Thaler MM, Park CK, Landers DV, Wara D, Houghton M, Veereman-Wauters G, Sweet RL, Han JH. Vertical transmission of hepatitis C virus. Lancet. 1991 Jul 06; 338(8758):17-8. PMID: 1676085.
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    50. Martin NL, Levy JA, Legg H, Weintrub PS, Cowan MJ, Wara D. Detection of infection with human immunodeficiency virus (HIV) type 1 in infants by an anti-HIV immunoglobulin A assay using recombinant proteins. J Pediatr. 1991 Mar; 118(3):354-8. PMID: 1705583.
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    51. Halberg FE, Wara WM, Weaver KE, Wara D, Ablin AR, Matthay KK, Mentzer WC, O'Leary MC, Cowan MJ. Total body irradiation and bone marrow transplantation for immunodeficiency disorders in young children. Radiother Oncol. 1990; 18 Suppl 1:114-7. PMID: 2247633.
      View in: PubMed
    52. Edwards JR, Ulrich PP, Weintrub PS, Cowan MJ, Levy JA, Wara D, Vyas GN. Polymerase chain reaction compared with concurrent viral cultures for rapid identification of human immunodeficiency virus infection among high-risk infants and children. J Pediatr. 1989 Aug; 115(2):200-3. PMID: 2754549.
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    53. Cowan MJ, Walker C, Culver K, Weintrub PS, Wara D, Levy JA. Maternally transmitted HIV infection in children. AIDS. 1988 Dec; 2(6):437-41. PMID: 3149491.
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    54. Cowan MJ, Shannon KM, Wara D, Ammann AJ. Rejection of bone marrow transplant and resistance of alloantigen reactive cells to in vivo deoxyadenosine in adenosine deaminase deficiency. Clin Immunol Immunopathol. 1988 Nov; 49(2):242-50. PMID: 2971490.
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    55. Ray PE, Rigolizzo D, Wara D, Piel CF. Naproxen nephrotoxicity in a 2-year-old child. Am J Dis Child. 1988 May; 142(5):524-5. PMID: 3358393.
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    56. Culver KW, Ammann AJ, Partridge JC, Wong DF, Wara D, Cowan MJ. Lymphocyte abnormalities in infants born to drug-abusing mothers. J Pediatr. 1987 Aug; 111(2):230-5. PMID: 3039102.
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    57. Rutherford GW, Oliva GE, Grossman M, Green JR, Wara D, Shaw NS, Echenberg DF, Wofsy CB, Weinstein DH, Stroud F. Guidelines for the control of perinatally transmitted human immunodeficiency virus infection and care of infected mothers, infants and children. West J Med. 1987 Jul; 147(1):104-8. PMID: 3424801; PMCID: PMC1025844.
    58. Matthay K, Wara D, Ablin AJ, Cowan MJ. Haploidentical bone marrow transplantation using soybean agglutinin-processed, T-depleted marrow. Transplant Proc. 1987 Feb; 19(1 Pt 3):2678-9. PMID: 3274578.
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    59. Cowan MJ, Wara D, Weintrub PS, Pabst H, Ammann AJ. Haploidentical bone marrow transplantation for severe combined immunodeficiency disease using soybean agglutinin-negative, T-depleted marrow cells. J Clin Immunol. 1985 Nov; 5(6):370-6. PMID: 3910675.
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    60. Cowan MJ, Wara D, Ammann AJ. Deoxycytidine therapy in two patients with adenosine deaminase deficiency and severe immunodeficiency disease. Clin Immunol Immunopathol. 1985 Oct; 37(1):30-6. PMID: 3161676.
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    61. Ammann AJ, Johnson A, Fyfe GA, Leonards R, Wara D, Cowan MJ. Behçet syndrome. J Pediatr. 1985 Jul; 107(1):41-3. PMID: 4009339.
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    62. Wara D. Immune regulation: what immunodeficiency disease has taught us. J Invest Dermatol. 1985 Jul; 85(1 Suppl):149s-154s. PMID: 2989376.
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    63. Ochs HD, Fischer SH, Wedgwood RJ, Wara D, Cowan MJ, Ammann AJ, Saxon A, Budinger MD, Allred RU, Rousell RH. Comparison of high-dose and low-dose intravenous immunoglobulin therapy in patients with primary immunodeficiency diseases. Am J Med. 1984 Mar 30; 76(3A):78-82. PMID: 6424461.
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    64. Cowan MJ, Hellmann D, Chudwin D, Wara D, Chang RS, Ammann AJ. Maternal transmission of acquired immune deficiency syndrome. Pediatrics. 1984 Mar; 73(3):382-6. PMID: 6608091.
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    65. Ammann AJ, Wara D, Cowan MJ. Pediatric acquired immunodeficiency syndrome. Ann N Y Acad Sci. 1984; 437:340-9. PMID: 6242000.
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    66. Cowan MJ, Martin DW, Wara D, Ammann AJ. Intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency. Adv Exp Med Biol. 1984; 165 Pt A:39-45. PMID: 6609530.
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    67. Chudwin DS, Ammann AJ, Cowan MJ, Wara D. Significance of a positive antinuclear antibody test in a pediatric population. Am J Dis Child. 1983 Nov; 137(11):1103-6. PMID: 6356882.
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    68. Hellmann D, Cowan MJ, Ammann AJ, Wara D, Chudwin D, Chang RS. Chronic active Epstein-Barr virus infections in two immunodeficient patients. J Pediatr. 1983 Oct; 103(4):585-8. PMID: 6312007.
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    69. Chudwin DS, Cowan MJ, Greenberg PL, Wara D, Ammann AJ. Response of agranulocytosis to prolonged antithymocyte globulin therapy. J Pediatr. 1983 Aug; 103(2):223-7. PMID: 6875713.
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    70. Savouret JF, Chudwin DS, Wara D, Ammann AJ, Cowan MJ, Miller WL. Clinical and laboratory findings in childhood mixed connective tissue disease: presence of antibody to ribonucleoprotein containing the small nuclear ribonucleic acid U1. J Pediatr. 1983 Jun; 102(6):841-6. PMID: 6189985.
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    71. Ammann AJ, Cowan MJ, Wara D, Weintrub P, Dritz S, Goldman H, Perkins HA. Acquired immunodeficiency in an infant: possible transmission by means of blood products. Lancet. 1983 Apr 30; 1(8331):956-8. PMID: 6132270.
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    72. Chudwin DS, Cowan MJ, Wara D, Ammann AJ. Patients with abnormal proportions of T-lymphocyte subsets have reduced in vitro cellular immunity. Clin Immunol Immunopathol. 1983 Jan; 26(1):126-36. PMID: 6223739.
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    73. Ammann AJ, Cowan MJ, Martin DW, Wara D. Dipyridamole and intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency. Birth Defects Orig Artic Ser. 1983; 19(3):117-20. PMID: 6652234.
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    74. Chudwin DS, Wara D, Cowan MJ, Ammann AJ. Aspergillus pneumonia in chronic granulomatous disease: recurrence and long-term outcome. Acta Paediatr Scand. 1982 Nov; 71(6):915-7. PMID: 7158331.
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    75. Ammann AJ, Wara D, Cowan MJ, Barrett DJ, Stiehm ER. The DiGeorge syndrome and the fetal alcohol syndrome. Am J Dis Child. 1982 Oct; 136(10):906-8. PMID: 6812410.
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    76. Chudwin DS, Ammann AJ, Wara D, Cowan MJ, Phibbs RH. Posttransfusion syndrome. Rash, eosinophilia, and thrombocytopenia following intrauterine and exchange transfusions. Am J Dis Child. 1982 Jul; 136(7):612-4. PMID: 7201237.
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    77. Ammann AJ, Ashman RF, Buckley RH, Hardie WR, Krantmann HJ, Nelson J, Ochs H, Stiehm ER, Tiller T, Wara D, Wedgwood R. Use of intravenous gamma-globulin in antibody immunodeficiency: results of a multicenter controlled trial. Clin Immunol Immunopathol. 1982 Jan; 22(1):60-7. PMID: 6749355.
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    78. Barrett DJ, Ammann AJ, Wara D, Cowan MJ, Fisher TJ, Stiehm ER. Clinical and immunologic spectrum of the DiGeorge syndrome. J Clin Lab Immunol. 1981 Jul; 6(1):1-6. PMID: 6973633.
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    79. Chudwin DS, Cowan MJ, Wara D, Johnson AC. Lung involvement in progressive vaccinia. West J Med. 1981 May; 134(5):446-8. PMID: 6973241; PMCID: PMC1272785.
    80. Chudwin DS, Daniels TE, Wara D, Ammann AJ, Barrett DJ, Whitcher JP, Cowan MJ. Spectrum of Sjögren syndrome in children. J Pediatr. 1981 Feb; 98(2):213-7. PMID: 7463216.
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    81. Cowan MJ, Fujiwara P, Wara D, Ammann AJ. Effect of thymosin on cellular immunity in old age. Mech Ageing Dev. 1981 Jan; 15(1):29-39. PMID: 6456383.
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    82. Sander JE, Malamud N, Cowan MJ, Packman S, Amman AJ, Wara D. Intermittent ataxia and immunodeficiency with multiple carboxylase deficiencies: a biotin-responsive disorder. Ann Neurol. 1980 Nov; 8(5):544-7. PMID: 7436398.
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