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Donald Easton, MD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Phone415-502-7329
EmailJDonaldEaston@ucsf.edu
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    New York Hospital-Cornell Medical CenterIntern1965Medicine
    University of WashingtonMD1964School of Medicine
    New York Hospital-Cornell Medical CenterResidency1968Neurology
    Washington State UniversityBS1960Zoology

    Collapse Overview 
    Collapse Overview
    J. Donald Easton, MD, was born in Saskatoon, Saskatchewan, Canada. He graduated with honors from the University of Washington School of Medicine and was elected to membership in Phi Beta Kappa and Alpha Omega Alpha. Dr. Easton completed his internship in medicine and residency in neurology at the New York Hospital-Cornell Medical Center and assumed his first academic appointment at the University of California at San Diego. In 1986 he was appointed Professor and Chair of the Department of Clinical Neurosciences at the Rhode Island Hospital and Alpert Medical School of Brown University. In January 2010 Dr. Easton joined our faculty in the Department of Neurology at UCSF to work with Dr. Clay Johnston on his NIH-funded POINT (Platelet-Oriented Inhibition in New TIA and minor ischemic stroke) trial.

    Dr. Easton has been a Director of the American Board of Psychiatry & Neurology, a Councilor of the American Neurological Association, an officer of the Association of University Professors of Neurology, Chairman of the Residency Review Committee for Neurology, Chairman of the American Heart Association Stroke Council, Chairman of the Neurological Disorders Program, Project Review Committee-A at the NIH, and a member of the NIH Advisory Council for the Neurological Institute.

    Dr. Easton has served on numerous Steering, Advisory, Organizing and Monitoring Committees for many clinical trials and congresses. He also has served on the editorial boards of many journals. He has published more than 300 journal articles, books, chapters & miscellaneous publications.

    He is an honorary member of the Stroke Society of Australasia, the Austrian Society for Stroke Research, the Belgian Stroke Society, the Brazilian Society of Cerebrovascular Diseases and the Mexican Association of Cerebral Vascular Disease.

    Collapse Research 
    Collapse Research Activities and Funding
    POINT: PLATELET-ORIENTED INHIBITION IN NEW TIA
    NIH/NINDS U01NS062835Sep 30, 2009 - Apr 30, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Farrant M, Easton JD, Adelman EE, Cucchiara BL, Barsan WG, Tillman HJ, Elm JJ, Kim AS, Lindblad AS, Palesch YY, Zhao W, Pauls K, Walsh KB, Martí-Fàbregas J, Bernstein RA, Johnston SC. Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis. JAMA Netw Open. 2019 Sep 04; 2(9):e1910769. PMID: 31490536.
      View in: PubMed
    2. Pan Y, Elm JJ, Li H, Easton JD, Wang Y, Farrant M, Meng X, Kim AS, Zhao X, Meurer WJ, Liu L, Dietrich D, Wang Y, Johnston SC. Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: A Pooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-Disabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trials. JAMA Neurol. 2019 Aug 19. PMID: 31424481.
      View in: PubMed
    3. Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA. Resolving medulloblastoma cellular architecture by single-cell genomics. Nature. 2019 08; 572(7767):74-79. PMID: 31341285.
      View in: PubMed
    4. Tillman H, Johnston SC, Farrant M, Barsan W, Elm JJ, Kim AS, Lindblad AS, Palesch YY, Easton JD. Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial. JAMA Neurol. 2019 Jul 01; 76(7):774-782. PMID: 31034032.
      View in: PubMed
    5. Johnston SC, Elm JJ, Easton JD, Farrant M, Barsan WG, Kim AS, Lindblad AS, Palesch YY, Zurita KG, Albers GW, Cucchiara BL, Kleindorfer DO, Lutsep HL, Pearson C, Sethi P, Vora N. Time Course for Benefit and Risk of Clopidogrel and Aspirin After Acute Transient Ischemic Attack and Minor Ischemic Stroke. Circulation. 2019 Aug 20; 140(8):658-664. PMID: 31238700.
      View in: PubMed
    6. Toyoda K, Uchiyama S, Yamaguchi T, Easton JD, Kimura K, Hoshino H, Sakai N, Okada Y, Tanaka K, Origasa H, Naritomi H, Houkin K, Yamaguchi K, Isobe M, Minematsu K. Dual antiplatelet therapy using cilostazol for secondary prevention in patients with high-risk ischaemic stroke in Japan: a multicentre, open-label, randomised controlled trial. Lancet Neurol. 2019 Jun; 18(6):539-548. PMID: 31122494.
      View in: PubMed
    7. Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S, Kreuzer J, Cronin L, Cotton D, Grauer C, Brueckmann M, Chernyatina M, Donnan G, Ferro JM, Grond M, Kallmünzer B, Krupinski J, Lee BC, Lemmens R, Masjuan J, Odinak M, Saver JL, Schellinger PD, Toni D, Toyoda K. Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. N Engl J Med. 2019 05 16; 380(20):1906-1917. PMID: 31091372.
      View in: PubMed
    8. Easton JD, Denison H, Evans SR, Knutsson M, Amarenco P, Albers GW, Ladenvall P, Minematsu K, Molina CA, Wang Y, Wong KL, Johnston SC. Estimated treatment effect of ticagrelor versus aspirin by investigator-assessed events compared with judgement by an independent event adjudication committee in the SOCRATES trial. Int J Stroke. 2019 Dec; 14(9):908-914. PMID: 31092152.
      View in: PubMed
    9. Molina CA, Johnston SC, Ladenvall P, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Knutsson M, Minematsu K, Röther J, Wang Y, Wong KSL. Time to Loading Dose and Risk of Recurrent Events in the SOCRATES Trial. Stroke. 2019 03; 50(3):675-682. PMID: 30776996.
      View in: PubMed
    10. Kim AS, Easton JD. New opportunities to optimize antithrombotic therapy for secondary stroke prevention. Int J Stroke. 2019 04; 14(3):220-222. PMID: 30722755.
      View in: PubMed
    11. Xu K, Ding L, Chang TC, Shao Y, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, Downing JR, Ellison DW, Zhang J, Baker SJ, Wu G. Structure and evolution of double minutes in diagnosis and relapse brain tumors. Acta Neuropathol. 2019 01; 137(1):123-137. PMID: 30267146.
      View in: PubMed
    12. Diener HC, Ntaios G, O'Donnell M, Easton JD. Non-vitamin-K oral anticoagulants (NOACs) for the prevention of secondary stroke. Expert Opin Pharmacother. 2018 Oct; 19(14):1597-1602. PMID: 30152249.
      View in: PubMed
    13. Wong KSL, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Himmelmann A, Kasner SE, Knutsson M, Ladenvall P, Minematsu K, Molina CA, Wang Y, Johnston SC. Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial. Stroke. 2018 07; 49(7):1678-1685. PMID: 29915123.
      View in: PubMed
    14. Wang Z, Wilson CL, Easton J, Thrasher A, Mulder H, Liu Q, Hedges DJ, Wang S, Rusch MC, Edmonson MN, Levy S, Lanctot JQ, Caron E, Shelton K, Currie K, Lear M, Patel A, Rosencrance C, Shao Y, Vadodaria B, Yergeau D, Sapkota Y, Brooke RJ, Moon W, Rampersaud E, Ma X, Chang TC, Rice SV, Pepper C, Zhou X, Chen X, Chen W, Jones A, Boone B, Ehrhardt MJ, Krasin MJ, Howell RM, Phillips NS, Lewis C, Srivastava D, Pui CH, Kesserwan CA, Wu G, Nichols KE, Downing JR, Hudson MM, Yasui Y, Robison LL, Zhang J. Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer. J Clin Oncol. 2018 07 10; 36(20):2078-2087. PMID: 29847298.
      View in: PubMed
    15. Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, Kim AS, Lindblad AS, Palesch YY. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. N Engl J Med. 2018 Jul 19; 379(3):215-225. PMID: 29766750.
      View in: PubMed
    16. Goto S, Merrill P, Wallentin L, Wojdyla DM, Hanna M, Avezum A, Easton JD, Harjola VP, Huber K, Lewis BS, Parkhomenko A, Zhu J, Granger CB, Lopes RD, Alexander JH. Antithrombotic therapy use and clinical outcomes following thrombo-embolic events in patients with atrial fibrillation: insights from ARISTOTLE. Eur Heart J Cardiovasc Pharmacother. 2018 04 01; 4(2):75-81. PMID: 29385429.
      View in: PubMed
    17. Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Hill MD, Jonasson J, Kasner SE, Ladenvall P, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC. Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source. Stroke. 2017 09; 48(9):2480-2487. PMID: 28720658.
      View in: PubMed
    18. Easton JD, Aunes M, Albers GW, Amarenco P, Bokelund-Singh S, Denison H, Evans SR, Held P, Jahreskog M, Jonasson J, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC. Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes). Circulation. 2017 Sep 05; 136(10):907-916. PMID: 28655834.
      View in: PubMed
    19. Lopes RD, Guimarães PO, Kolls BJ, Wojdyla DM, Bushnell CD, Hanna M, Easton JD, Thomas L, Wallentin L, Al-Khatib SM, Held C, Gabriel Melo de Barros E Silva P, Alexander JH, Granger CB, Diener HC. Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy. Blood. 2017 06 01; 129(22):2980-2987. PMID: 28356246.
      View in: PubMed
    20. Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Hill MD, Jonasson J, Kasner SE, Ladenvall P, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC. Efficacy and safety of ticagrelor versus aspirin in acute stroke or transient ischaemic attack of atherosclerotic origin: a subgroup analysis of SOCRATES, a randomised, double-blind, controlled trial. Lancet Neurol. 2017 Apr; 16(4):301-310. PMID: 28238711.
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    21. Easton JD. Henry J.M. Barnett, MD, FRCP (C). J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2791. PMID: 27955755.
      View in: PubMed
    22. Wang Y, Minematsu K, Wong KS, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Jonasson J, Molina CA, Johnston SC. Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes). Stroke. 2017 01; 48(1):167-173. PMID: 27899747.
      View in: PubMed
    23. Kim AS, Easton JD, Johnston SC. Risk of Stroke after Transient Ischemic Attack or Minor Stroke. N Engl J Med. 2016 07 28; 375(4):386-7. PMID: 27464212.
      View in: PubMed
    24. Johnston SC, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Jonasson J, Minematsu K, Molina CA, Wang Y, Wong KS. Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack. N Engl J Med. 2016 Jul 07; 375(1):35-43. PMID: 27160892.
      View in: PubMed
    25. Albers GW, Bernstein RA, Brachmann J, Camm J, Easton JD, Fromm P, Goto S, Granger CB, Hohnloser SH, Hylek E, Jaffer AK, Krieger DW, Passman R, Pines JM, Reed SD, Rothwell PM, Kowey PR. Heart Rhythm Monitoring Strategies for Cryptogenic Stroke: 2015 Diagnostics and Monitoring Stroke Focus Group Report. J Am Heart Assoc. 2016 Mar 15; 5(3):e002944. PMID: 27068633.
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    26. Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR, Vadodaria B, Chen X, McGee RB, Hines-Dowell S, Nuccio R, Quinn E, Shurtleff SA, Rusch M, Patel A, Becksfort JB, Wang S, Weaver MS, Ding L, Mardis ER, Wilson RK, Gajjar A, Ellison DW, Pappo AS, Pui CH, Nichols KE, Downing JR. Germline Mutations in Predisposition Genes in Pediatric Cancer. N Engl J Med. 2015 Dec 10; 373(24):2336-2346. PMID: 26580448.
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    27. Diener HC, Easton JD, Granger CB, Cronin L, Duffy C, Cotton D, Brueckmann M, Sacco RL. Design of Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE-SPECT ESUS). Int J Stroke. 2015 Dec; 10(8):1309-12. PMID: 26420134.
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    28. Johnston SC, Amarenco P, Albers GW, Denison H, Easton JD, Held P, Jonasson J, Minematsu K, Molina CA, Wong LK. Acute Stroke or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes (SOCRATES) trial: rationale and design. Int J Stroke. 2015 Dec; 10(8):1304-8. PMID: 26311628.
      View in: PubMed
    29. Elm JJ, Palesch Y, Easton JD, Lindblad A, Barsan W, Silbergleit R, Conwit R, Dillon C, Farrant M, Battenhouse H, Perlmutter A, Johnston SC. Screen failure data in clinical trials: Are screening logs worth it? Clin Trials. 2014 Aug; 11(4):467-472. PMID: 24925082.
      View in: PubMed
    30. Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O'Donnell MJ, Sacco RL, Connolly SJ. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. 2014 Apr; 13(4):429-38. PMID: 24646875.
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    31. Easton JD. History of carotid endarterectomy then and now: personal perspective. Stroke. 2014 Jun; 45(6):e101-3. PMID: 24399374.
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    32. Johnston SC, Easton JD, Farrant M, Barsan W, Battenhouse H, Conwit R, Dillon C, Elm J, Lindblad A, Morgenstern L, Poisson SN, Palesch Y. Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. Int J Stroke. 2013 Aug; 8(6):479-83. PMID: 23879752.
      View in: PubMed
    33. Diener HC, Easton JD, Hankey GJ, Hart RG. Novel oral anticoagulants in secondary prevention of stroke. Best Pract Res Clin Haematol. 2013 Jun; 26(2):131-9. PMID: 23953901.
      View in: PubMed
    34. Kim AS, Poisson SN, Easton JD, Johnston SC. A cross-sectional study of individuals seeking information on transient ischemic attack and stroke symptoms online: a target for intervention? PLoS One. 2012; 7(10):e47997. PMID: 23118919.
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    35. Lopes RD, Al-Khatib SM, Wallentin L, Yang H, Ansell J, Bahit MC, De Caterina R, Dorian P, Easton JD, Erol C, Ezekowitz JA, Gersh BJ, Granger CB, Hohnloser SH, Horowitz J, Hylek EM, McMurray JJ, Mohan P, Vinereanu D, Alexander JH. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet. 2012 Nov 17; 380(9855):1749-58. PMID: 23036896.
      View in: PubMed
    36. Kamel H, Easton JD, Johnston SC, Kim AS. Cost-effectiveness of apixaban vs warfarin for secondary stroke prevention in atrial fibrillation. Neurology. 2012 Oct 02; 79(14):1428-34. PMID: 22993279.
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    37. Easton JD, Lopes RD, Bahit MC, Wojdyla DM, Granger CB, Wallentin L, Alings M, Goto S, Lewis BS, Rosenqvist M, Hanna M, Mohan P, Alexander JH, Diener HC. Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. Lancet Neurol. 2012 Jun; 11(6):503-11. PMID: 22572202.
      View in: PubMed
    38. Kamel H, Johnston SC, Easton JD, Kim AS. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in patients with atrial fibrillation and prior stroke or transient ischemic attack. Stroke. 2012 Mar; 43(3):881-3. PMID: 22308255.
      View in: PubMed
    39. Granger CB, Alexander JH, McMurray JJ, Lopes RD, Hylek EM, Hanna M, Al-Khalidi HR, Ansell J, Atar D, Avezum A, Bahit MC, Diaz R, Easton JD, Ezekowitz JA, Flaker G, Garcia D, Geraldes M, Gersh BJ, Golitsyn S, Goto S, Hermosillo AG, Hohnloser SH, Horowitz J, Mohan P, Jansky P, Lewis BS, Lopez-Sendon JL, Pais P, Parkhomenko A, Verheugt FW, Zhu J, Wallentin L. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011 Sep 15; 365(11):981-92. PMID: 21870978.
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    40. Easton JD. Antithrombotic management for transient ischemic attack and ischemic stroke (other than atrial fibrillation). Curr Atheroscler Rep. 2011 Aug; 13(4):314-20. PMID: 21584696.
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    41. Hankey GJ, Johnston SC, Easton JD, Hacke W, Mas JL, Brennan D, Mak KH, Bhatt DL, Fox KA, Topol EJ. Effect of clopidogrel plus ASA vs. ASA early after TIA and ischaemic stroke: a substudy of the CHARISMA trial. Int J Stroke. 2011 Feb; 6(1):3-9. PMID: 21205234.
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    42. Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL. Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial. Lancet. 2010 Aug 14; 376(9740):517-23. PMID: 20709233.
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    43. Hankey GJ, Hacke W, Easton JD, Johnston SC, Mas JL, Brennan DM, Bhatt DL, Fox KA, Topol EJ. Effect of clopidogrel on the rate and functional severity of stroke among high vascular risk patients: a prespecified substudy of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA) trial. Stroke. 2010 Aug; 41(8):1679-83. PMID: 20595658.
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    44. Easton JD, Feldmann E. A new technique to stratify stroke risk in transient ischemic attack patients? Ann Neurol. 2010 Jul; 68(1):1-2. PMID: 20583217.
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    45. Lopes RD, Alexander JH, Al-Khatib SM, Ansell J, Diaz R, Easton JD, Gersh BJ, Granger CB, Hanna M, Horowitz J, Hylek EM, McMurray JJ, Verheugt FW, Wallentin L. Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale. Am Heart J. 2010 Mar; 159(3):331-9. PMID: 20211292.
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    46. Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E, Hatsukami TS, Higashida RT, Johnston SC, Kidwell CS, Lutsep HL, Miller E, Sacco RL. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke. 2009 Jun; 40(6):2276-93. PMID: 19423857.
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    47. Mak KH, Bhatt DL, Shao M, Hankey GJ, Easton JD, Fox KA, Topol EJ. Ethnic variation in adverse cardiovascular outcomes and bleeding complications in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) study. Am Heart J. 2009 Apr; 157(4):658-65. PMID: 19332192.
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    48. Eikelboom JW, Hankey GJ, Thom J, Bhatt DL, Steg PG, Montalescot G, Johnston SC, Steinhubl SR, Mak KH, Easton JD, Hamm C, Hu T, Fox KA, Topol EJ. Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. Circulation. 2008 Oct 21; 118(17):1705-12. PMID: 18838564.
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    49. Aronow HD, Califf RM, Harrington RA, Vallee M, Graffagnino C, Shuaib A, Fitzgerald DJ, Easton JD, Van de Werf F, Diener HC, Ferguson J, Koudstaal PJ, Amarenco P, Theroux P, Davis S, Topol EJ. Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial). Am J Cardiol. 2008 Nov 15; 102(10):1285-90. PMID: 18993142.
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    50. Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P. Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008 Jun; 133(6 Suppl):630S-669S. PMID: 18574275.
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    51. Inrig JK, Patel UD, Briley LP, She L, Gillespie BS, Easton JD, Topol EJ, Szczech LA. Mortality, kidney disease and cardiac procedures following acute coronary syndrome. Nephrol Dial Transplant. 2008 Mar; 23(3):934-40. PMID: 17984102.
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    52. Inrig JK, Gillespie BS, Patel UD, Briley LP, She L, Easton JD, Topol E, Szczech LA. Risk for cardiovascular outcomes among subjects with atherosclerotic cardiovascular disease and greater-than-normal estimated glomerular filtration rate. Clin J Am Soc Nephrol. 2007 Nov; 2(6):1215-22. PMID: 17942781.
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    53. Bhatt DL, Flather MD, Hacke W, Berger PB, Black HR, Boden WE, Cacoub P, Cohen EA, Creager MA, Easton JD, Hamm CW, Hankey GJ, Johnston SC, Mak KH, Mas JL, Montalescot G, Pearson TA, Steg PG, Steinhubl SR, Weber MA, Fabry-Ribaudo L, Hu T, Topol EJ, Fox KA. Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial. J Am Coll Cardiol. 2007 May 15; 49(19):1982-8. PMID: 17498584.
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    54. Easton JD. Dipyridamole plus aspirin for stroke prevention. Lancet Neurol. 2006 Jul; 5(7):553-4. PMID: 16781983.
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    55. Bushnell CD, Griffin J, Newby LK, Goldstein LB, Mahaffey KW, Graffagnino CA, Harrington RA, White HD, Simes RJ, Califf RM, Topol EJ, Easton JD. Statin use and sex-specific stroke outcomes in patients with vascular disease. Stroke. 2006 Jun; 37(6):1427-31. PMID: 16645137.
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    56. Bhatt DL, Fox KA, Hacke W, Berger PB, Black HR, Boden WE, Cacoub P, Cohen EA, Creager MA, Easton JD, Flather MD, Haffner SM, Hamm CW, Hankey GJ, Johnston SC, Mak KH, Mas JL, Montalescot G, Pearson TA, Steg PG, Steinhubl SR, Weber MA, Brennan DM, Fabry-Ribaudo L, Booth J, Topol EJ. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006 Apr 20; 354(16):1706-17. PMID: 16531616.
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    57. Bhatt DL, Fox KA, Hacke W, Berger PB, Black HR, Boden WE, Cacoub P, Cohen EA, Creager MA, Easton JD, Flather MD, Haffner SM, Hamm CW, Hankey GJ, Johnston SC, Mak KH, Mas JL, Montalescot G, Pearson TA, Steg PG, Steinhubl SR, Weber MA, Booth J, Topol EJ. A global view of atherothrombosis: baseline characteristics in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial. Am Heart J. 2005 Sep; 150(3):401. PMID: 16169314.
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    58. Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P. Antithrombotic and thrombolytic therapy for ischemic stroke: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004 Sep; 126(3 Suppl):483S-512S. PMID: 15383482.
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    59. Creager MA, Jones DW, Easton JD, Halperin JL, Hirsch AT, Matsumoto AH, O'Gara PT, Safian RD, Schwartz GL, Spittell JA. Atherosclerotic Vascular Disease Conference: Writing Group V: medical decision making and therapy. Circulation. 2004 Jun 01; 109(21):2634-42. PMID: 15173046.
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    60. Easton JD, Albers GW, Caplan LR, Saver JL, Sherman DG. Discussion: Reconsideration of TIA terminology and definitions. Neurology. 2004 Apr 27; 62(8 Suppl 6):S29-34. PMID: 15111655.
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    61. Johnston SC, Easton JD. Are patients with acutely recovered cerebral ischemia more unstable? Stroke. 2003 Oct; 34(10):2446-50. PMID: 12958326.
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    62. Easton JD. Evidence with antiplatelet therapy and ADP-receptor antagonists. Cerebrovasc Dis. 2003; 16 Suppl 1:20-6. PMID: 12698015.
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    63. Albers GW, Caplan LR, Easton JD, Fayad PB, Mohr JP, Saver JL, Sherman DG. Transient ischemic attack--proposal for a new definition. N Engl J Med. 2002 Nov 21; 347(21):1713-6. PMID: 12444191.
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    64. Alberts MJ, Easton JD. Clopidogrel plus aspirin for stroke prevention. Stroke. 2002 Nov; 33(11):2546-7; author reply 2546-7. PMID: 12411639.
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