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Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide. Acta Pharmacol Sin. 2023 Mar; 44(3):670-679.
Choo M, Mai VH, Kim HS, Kim DH, Ku JL, Lee SK, Park CK, An YJ, Park S. PMID: 36100765; PMCID: PMC9958008.
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1 Fields:
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HumansCells
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Antiproliferative Activity of a New Quinazolin-4(3H)-One Derivative via Targeting Aurora Kinase A in Non-Small Cell Lung Cancer. Pharmaceuticals (Basel). 2022 Jun 02; 15(6).
Lee JY, Yang H, Kim D, Kyaw KZ, Hu R, Fan Y, Lee SK. PMID: 35745617; PMCID: PMC9228987.
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1
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Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy. J Med Chem. 2021 05 13; 64(9):5535-5550.
Kim D, Choi SW, Cho J, Been JH, Choi K, Jiang W, Han J, Oh J, Park C, Choi S, Seo S, Kim KL, Suh W, Lee SK, Kim S. PMID: 33902285.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Nitidumpeptins A and B, Cyclohexapeptides Isolated from Zanthoxylum nitidum var. tomentosum: Structural Elucidation, Total Synthesis, and Antiproliferative Activity in Cancer Cells. J Org Chem. 2021 01 15; 86(2):1462-1470.
Qin F, Wang CY, Kim D, Wang HS, Zhu YK, Lee SK, Yao GY, Liang D. PMID: 33410687.
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HumansAnimals
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Anti-Proliferative Activity of Nodosin, a Diterpenoid from Isodon serra, via Regulation of Wnt/β-Catenin Signaling Pathways in Human Colon Cancer Cells. Biomol Ther (Seoul). 2020 Sep 01; 28(5):465-472.
Bae ES, Kim YM, Kim DH, Byun WS, Park HJ, Chin YW, Lee SK. PMID: 32394670; PMCID: PMC7457175.
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2
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The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation. Pharmacol Res. 2020 10; 160:105147.
Fan YH, Ding HW, Kim D, Liu JY, Hong JY, Xu YN, Wang D, Yang XS, Lee SK. PMID: 32814167.
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PubMed Mentions:
3 Fields:
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HumansCells
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Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtioserectus. Mar Drugs. 2020 May 13; 18(5).
Kwon OS, Kim D, Kim CK, Sun J, Sim CJ, Oh DC, Lee SK, Oh KB, Shin J. PMID: 32414015; PMCID: PMC7281328.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Overexpression of AGR2 Is Associated With Drug Resistance in Mutant Non-small Cell Lung Cancers. Anticancer Res. 2020 Apr; 40(4):1855-1866.
Luu TT, Bach DH, Kim D, Hu R, Park HJ, Lee SK. PMID: 32234873.
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PubMed Mentions:
9 Fields:
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Humans
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Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020 02; 6(6):eaav7416.
Aldonza MBD, Ku J, Hong JY, Kim D, Yu SJ, Lee MS, Prayogo MC, Tan S, Kim D, Han J, Lee SK, Im SG, Ryu HS, Kim Y. PMID: 32083171; PMCID: PMC7007258.
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PubMed Mentions:
13 Fields:
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HumansCells
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Photoprotective Activity of Topsentin, A Bis(Indole) Alkaloid from the Marine Sponge Spongosorites genitrix, by Regulation of COX-2 and Mir-4485 Expression in UVB-Irradiated Human Keratinocyte Cells. Mar Drugs. 2020 Jan 29; 18(2).
Hwang J, Kim D, Park JS, Park HJ, Shin J, Lee SK. PMID: 32013063; PMCID: PMC7073676.
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9 Fields:
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AnimalsCells
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Photoprotective effects of 2S,3R-6-methoxycarbonylgallocatechin isolated from Anhua dark tea on UVB-induced inflammatory responses in human keratinocytes. J Photochem Photobiol B. 2020 Jan; 202:111704.
Kim D, Hu R, Fan Y, Xu YN, Park HJ, Lee SK. PMID: 31743829.
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7 Fields:
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HumansCells
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Glechomanamides A-C, Germacrane Sesquiterpenoids with an Unusual Δ8-7,12-Lactam Moiety from Salvia scapiformis and Their Antiangiogenic Activity. J Nat Prod. 2019 11 22; 82(11):3056-3064.
Wang CY, Kim D, Zhu YK, Oh DC, Huang RZ, Wang HS, Liang D, Lee SK. PMID: 31668072.
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4 Fields:
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HumansAnimalsCells
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Antitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells. J Nat Prod. 2019 11 22; 82(11):3140-3149.
Kim D, Wang CY, Hu R, Lee JY, Luu TT, Park HJ, Lee SK. PMID: 31622095.
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PubMed Mentions:
9 Fields:
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HumansAnimalsCells
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Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer. Mol Ther Oncolytics. 2019 Dec 20; 15:140-152.
Byun WS, Kim WK, Han HJ, Chung HJ, Jang K, Kim HS, Kim S, Kim D, Bae ES, Park S, Lee J, Park HG, Lee SK. PMID: 31720371; PMCID: PMC6838941.
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17
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Neuroprotective effect of catechins derivatives isolated from Anhua dark tea on NMDA-induced excitotoxicity in SH-SY5Y cells. Fitoterapia. 2019 Sep; 137:104240.
Liu J, Fan Y, Kim D, Zhong T, Yi P, Fan C, Wang A, Yang X, Lee S, Ren X, Xu Y. PMID: 31201887.
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5 Fields:
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HumansCells
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Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer. Cancers (Basel). 2019 May 05; 11(5).
Fan Y, Ding H, Kim D, Bach DH, Hong JY, Xu Y, Lee SK. PMID: 31060329; PMCID: PMC6562471.
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4
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AXL degradation in combination with EGFR-TKI can delay and overcome acquired resistance in human non-small cell lung cancer cells. Cell Death Dis. 2019 05 01; 10(5):361.
Kim D, Bach DH, Fan YH, Luu TT, Hong JY, Park HJ, Lee SK. PMID: 31043587; PMCID: PMC6494839.
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PubMed Mentions:
39 Fields:
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AnimalsCells
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Camporidines A and B: Antimetastatic and Anti-inflammatory Polyketide Alkaloids from a Gut Bacterium of Camponotus kiusiuensis. J Nat Prod. 2019 04 26; 82(4):903-910.
Hong SH, Ban YH, Byun WS, Kim D, Jang YJ, An JS, Shin B, Lee SK, Shin J, Yoon YJ, Oh DC. PMID: 30912943.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Phenalenones from a Marine-Derived Fungus Penicillium Sp. Mar Drugs. 2019 Mar 18; 17(3).
Park SC, Julianti E, Ahn S, Kim D, Lee SK, Noh M, Oh DC, Oh KB, Shin AJ. PMID: 30889916; PMCID: PMC6470642.
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7 Fields:
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HumansAnimalsCells
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Bromopyrrole Alkaloids from the Sponge Agelas kosrae. Mar Drugs. 2018 Dec 17; 16(12).
Kwon OS, Kim D, Kim H, Lee YJ, Lee HS, Sim CJ, Oh DC, Lee SK, Oh KB, Shin J. PMID: 30563015; PMCID: PMC6316234.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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BMP4 Upregulation Is Associated with Acquired Drug Resistance and Fatty Acid Metabolism in EGFR-Mutant Non-Small-Cell Lung Cancer Cells. Mol Ther Nucleic Acids. 2018 Sep 07; 12:817-828.
Bach DH, Luu TT, Kim D, An YJ, Park S, Park HJ, Lee SK. PMID: 30153566; PMCID: PMC6118096.
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28
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Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells. Mol Ther Nucleic Acids. 2018 Jun 01; 11:455-467.
Bach DH, Kim D, Bae SY, Kim WK, Hong JY, Lee HJ, Rajasekaran N, Kwon S, Fan Y, Luu TT, Shin YK, Lee J, Lee SK. PMID: 29858080; PMCID: PMC5992482.
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35
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Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents. Bioorg Med Chem. 2017 07 01; 25(13):3396-3405.
Bach DH, Liu JY, Kim WK, Hong JY, Park SH, Kim D, Qin SN, Luu TT, Park HJ, Xu YN, Lee SK. PMID: 28478865.
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PubMed Mentions:
10 Fields:
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AnimalsCells
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Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway. J Dermatol Sci. 2017 Jul; 87(1):19-28.
Jang EJ, Shin Y, Park HJ, Kim D, Jung C, Hong JY, Kim S, Lee SK. PMID: 28390782.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells