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Ellen Mowry, MD

TitleAssistant Clinical Professor
SchoolUCSF School of Medicine
DepartmentNeurology
Address350 Parnassus Avenue
San Francisco CA 94117
Phone415-476-1361
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    Collapse Overview
    An Assistant Professor of Neurology, Dr. Mowry is working to determine if patients with MS who have low vitamin D levels have a more aggressive disease course. She will use the unique UCSF EPIC study, which is the only one of its kind in the United States, to answer this question. In this nearly complete, five-year study that includes over 500 people with MS, extensive genetic, imaging, and clinical evaluations are performed annually, providing a wealth of information to investigators. Dr. Mowry will determine if low vitamin D levels cause people with MS to have more attacks of the disease. She will also establish if vitamin D deficiency is associated with a greater rate of brain tissue loss, which is the cause of long-term disability in MS. Finally, Dr. Mowry will explore if genes related to vitamin D metabolism are determinants of MS severity and if vitamin D is metabolized the same way in people with and without MS. This project will set the stage for a large clinical trial of vitamin D supplementation in MS. The results of Dr. Mowry’s studies will have major implications for patients with MS throughout the world, as vitamin D is an inexpensive, natural therapy that could be used even by those are unable to afford the current MS medications.


    Collapse Research 
    Collapse Research Activities and Funding
    The effect of vitamin D on the clinical and imaging course of multiple sclerosis
    NIH/NINDS K23NS067055Jun 1, 2010 - Jun 30, 2015
    Role: Principal Investigator

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    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. LaRocca NG, Hudson LD, Rudick R, Amtmann D, Balcer L, Benedict R, Bermel R, Chang I, Chiaravalloti ND, Chin P, Cohen JA, Cutter GR, Davis MD, DeLuca J, Feys P, Francis G, Goldman MD, Hartley E, Kapoor R, Lublin F, Lundstrom G, Matthews PM, Mayo N, Meibach R, Miller DM, Motl RW, Mowry E, Naismith R, Neville J, Panagoulias J, Panzara M, Phillips G, Robbins A, Sidovar MF, Smith KE, Sperling B, Uitdehaag BM, Weaver J. The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability. Mult Scler. 2017 Aug 01; 1352458517723718. PMID: 28799444.
      View in: PubMed
    2. Foley RW, Tagg NT, Schindler MK, Fenton KM, Reich DS, Cortese I, Mowry E. Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis. Mult Scler. 2017 Sep; 23(10):1424-1427. PMID: 28639536.
      View in: PubMed
    3. Mowry E, McArthur JC. PML in natalizumab-treated multiple sclerosis: Modeling errors and risk miscalculations. Neurology. 2017 Mar 21; 88(12):1110-1111. PMID: 28228562.
      View in: PubMed
    4. Motl RW, Mowry E, Ehde DM, LaRocca NG, Smith KE, Costello K, Shinto L, Ng AV, Sullivan AB, Giesser B, McCully KK, Fernhall B, Bishop M, Plow M, Casaccia P, Chiaravalloti ND. Wellness and multiple sclerosis: The National MS Society establishes a Wellness Research Working Group and research priorities. Mult Scler. 2017 Jan 01; 1352458516687404. PMID: 28080254.
      View in: PubMed
    5. Freund B, Mowry E, Levy M, Newsome SD. Neuromyelitis optica unmasked by a spinal dural arteriovenous fistula. J Neuroimmunol. 2016 Nov 15; 300:18-20. PMID: 27806871.
      View in: PubMed
    6. Pakpoor J, Saylor D, Izbudak I, Liu L, Mowry E, Yousem DM. Emergency Department MRI Scanning of Patients with Multiple Sclerosis: Worthwhile or Wasteful? AJNR Am J Neuroradiol. 2017 Jan; 38(1):12-17. PMID: 27758773.
      View in: PubMed
    7. Waubant E, Ponsonby AL, Pugliatti M, Hanwell H, Mowry E, Hintzen RQ. Environmental and genetic factors in pediatric inflammatory demyelinating diseases. Neurology. 2016 Aug 30; 87(9 Suppl 2):S20-7. PMID: 27572857.
      View in: PubMed
    8. Cree B, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL, et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Oct; 80(4):499-510. PMID: 27464262.
      View in: PubMed
    9. Williams TJ, Benavides DR, Patrice KA, Dalmau JO, de Ávila AL, Le DT, Lipson EJ, Probasco JC, Mowry E. Association of Autoimmune Encephalitis With Combined Immune Checkpoint Inhibitor Treatment for Metastatic Cancer. JAMA Neurol. 2016 Aug 01; 73(8):928-33. PMID: 27271951.
      View in: PubMed
    10. Mowry E. Haematopoietic stem cell transplants should be a second-line therapy for highly active MS - Commentary. Mult Scler. 2016 Sep; 22(10):1263-5. PMID: 27444561.
      View in: PubMed
    11. Glenn JD, Mowry E. Emerging Concepts on the Gut Microbiome and Multiple Sclerosis. J Interferon Cytokine Res. 2016 Jun; 36(6):347-57. PMID: 27145057.
      View in: PubMed
    12. Hedström AK, Mowry E, Gianfrancesco MA, Shao X, Schaefer CA, Shen L, Olsson T, Barcellos LF, Alfredsson L. High consumption of coffee is associated with decreased multiple sclerosis risk; results from two independent studies. J Neurol Neurosurg Psychiatry. 2016 May; 87(5):454-60. PMID: 26940586; PMCID: PMC4853555.
    13. Graves JS, Barcellos LF, Shao X, Noble J, Mowry E, Quach H, Belman A, Casper TC, Krupp LB, Waubant E. Genetic predictors of relapse rate in pediatric MS. Mult Scler. 2016 Oct; 22(12):1528-1535. PMID: 26769066.
      View in: PubMed
    14. Sotirchos ES, Bhargava P, Eckstein C, Van Haren K, Baynes M, Ntranos A, Gocke A, Steinman L, Mowry E, Calabresi PA. Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. Neurology. 2016 Jan 26; 86(4):382-90. PMID: 26718578; PMCID: PMC4776090 [Available on 01/26/17].
    15. Yeshokumar AK, Saylor D, Kornberg MD, Mowry E. Evidence for the Importance of Vitamin D Status in Neurologic Conditions. Curr Treat Options Neurol. 2015 Dec; 17(12):51. PMID: 26538263.
      View in: PubMed
    16. Mowry E, Pelletier D, Gao Z, Howell MD, Zamvil SS, Waubant E. Vitamin D in clinically isolated syndrome: evidence for possible neuroprotection. Eur J Neurol. 2016 Feb; 23(2):327-32. PMID: 26518224.
      View in: PubMed
    17. Bhargava P, Steele SU, Waubant E, Revirajan NR, Marcus J, Dembele M, Cassard SD, Hollis BW, Crainiceanu C, Mowry E. Multiple sclerosis patients have a diminished serologic response to vitamin D supplementation compared to healthy controls. Mult Scler. 2016 May; 22(6):753-60. PMID: 26286698; PMCID: PMC4758937 [Available on 05/01/17].
    18. Cantarel BL, Waubant E, Chehoud C, Kuczynski J, DeSantis TZ, Warrington J, Venkatesan A, Fraser CM, Mowry E. Gut microbiota in multiple sclerosis: possible influence of immunomodulators. J Investig Med. 2015 Jun; 63(5):729-34. PMID: 25775034; PMCID: PMC4439263.
    19. Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry E, Rose JW, Simmons T, Casper TC, James J, Waubant E. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18; 83(21):1923-9. PMID: 25339213; PMCID: PMC4248458.
    20. Bhargava P, Cassard S, Steele SU, Azevedo C, Pelletier D, Sugar EA, Waubant E, Mowry E. The vitamin D to ameliorate multiple sclerosis (VIDAMS) trial: study design for a multicenter, randomized, double-blind controlled trial of vitamin D in multiple sclerosis. Contemp Clin Trials. 2014 Nov; 39(2):288-93. PMID: 25311447.
      View in: PubMed
    21. Bhargava P, Mowry E. Gut microbiome and multiple sclerosis. Curr Neurol Neurosci Rep. 2014 Oct; 14(10):492. PMID: 25204849.
      View in: PubMed
    22. Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry E, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E. Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis. Mult Scler Relat Disord. 2014 Nov; 3(6):720-7. PMID: 25891551.
      View in: PubMed
    23. Bermel R, Waldman A, Mowry E. Outcome measures in multiple sclerosis. Mult Scler Int. 2014; 2014:439375. PMID: 24883206; PMCID: PMC4026968.
    24. Waubant E, Maghzi AH, Revirajan N, Spain R, Julian L, Mowry E, Marcus J, Liu S, Jin C, Green A, McCulloch CE, Pelletier D. A randomized controlled phase II trial of riluzole in early multiple sclerosis. Ann Clin Transl Neurol. 2014 May; 1(5):340-7. PMID: 25356404; PMCID: PMC4184685.
    25. Graves J, Vinayagasundaram U, Mowry E, Matthews IR, Marino JA, Cheng J, Waubant E. Effects of rituximab on lymphocytes in multiple sclerosis and neuromyelitis optica. Mult Scler Relat Disord. 2014 Mar; 3(2):244-52. PMID: 25878012.
      View in: PubMed
    26. Mowry E, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E. Association of multiple sclerosis susceptibility variants and early attack location in the CNS. PLoS One. 2013; 8(10):e75565. PMID: 24130718; PMCID: PMC3794979.
    27. Mowry E, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E. Multiple sclerosis susceptibility genes: associations with relapse severity and recovery. PLoS One. 2013; 8(10):e75416. PMID: 24130709; PMCID: PMC3793991.
    28. Tan IL, Mowry E, Steele SU, Pardo CA, McArthur JC, Nath A, Venkatesan A. Brainstem encephalitis: etiologies, treatment, and predictors of outcome. J Neurol. 2013 Sep; 260(9):2312-9. PMID: 23749332; PMCID: PMC4939433.
    29. Waubant E, Mowry E, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, James JA. Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis. Mult Scler. 2013 Jun; 19(7):891-5. PMID: 23232601; PMCID: PMC3665694.
    30. von Geldern G, Mowry E. The influence of nutritional factors on the prognosis of multiple sclerosis. Nat Rev Neurol. 2012 Dec; 8(12):678-89. PMID: 23026980.
      View in: PubMed
    31. Mowry E, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D. Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis. Ann Neurol. 2012 Aug; 72(2):234-40. PMID: 22926855; PMCID: PMC3430977.
    32. Fay AJ, Mowry E, Strober J, Waubant E. Relapse severity and recovery in early pediatric multiple sclerosis. Mult Scler. 2012 Jul; 18(7):1008-12. PMID: 22183939.
      View in: PubMed
    33. Mowry E. Vitamin D: evidence for its role as a prognostic factor in multiple sclerosis. J Neurol Sci. 2011 Dec 15; 311(1-2):19-22. PMID: 21762931.
      View in: PubMed
    34. Waubant E, Mowry E, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Chabas D, Strober J, McDonald J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, Oksenberg JR, James JA. Common viruses associated with lower pediatric multiple sclerosis risk. Neurology. 2011 Jun 07; 76(23):1989-95. PMID: 21646624; PMCID: PMC3109881.
    35. Gelfand JM, Cree BA, McElroy J, Oksenberg J, Green R, Mowry E, Miller JW, Hauser SL, Green AJ. Vitamin D in African Americans with multiple sclerosis. Neurology. 2011 May 24; 76(21):1824-30. PMID: 21606454; PMCID: PMC3100123.
    36. Mowry E. Natural history of multiple sclerosis: early prognostic factors. Neurol Clin. 2011 May; 29(2):279-92. PMID: 21439441.
      View in: PubMed
    37. Castillo-Trivino T, Mowry E, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E. Switching multiple sclerosis patients with breakthrough disease to second-line therapy. PLoS One. 2011 Feb 03; 6(2):e16664. PMID: 21304907; PMCID: PMC3033401.
    38. Okuda DT, Mowry E, Cree BA, Crabtree EC, Goodin DS, Waubant E, Pelletier D. Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome. Neurology. 2011 Feb 22; 76(8):686-92. PMID: 21270417; PMCID: PMC3053327.
    39. Mowry E, James JA, Krupp LB, Waubant E. Vitamin D status and antibody levels to common viruses in pediatric-onset multiple sclerosis. Mult Scler. 2011 Jun; 17(6):666-71. PMID: 21212086; PMCID: PMC3134182.
    40. Mowry E, Waubant E. Pediatric multiple sclerosis. Continuum (Minneap Minn). 2010 Oct; 16(5 Multiple Sclerosis):181-92. PMID: 22810605.
      View in: PubMed
    41. Mowry E, Julian LJ, Im-Wang S, Chabas D, Galvin AJ, Strober JB, Waubant E. Health-related quality of life is reduced in pediatric multiple sclerosis. Pediatr Neurol. 2010 Aug; 43(2):97-102. PMID: 20610119.
      View in: PubMed
    42. Mowry E, Krupp LB, Milazzo M, Chabas D, Strober JB, Belman AL, McDonald JC, Oksenberg JR, Bacchetti P, Waubant E. Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis. Ann Neurol. 2010 May; 67(5):618-24. PMID: 20437559.
      View in: PubMed
    43. Kranick SM, Mowry E, Colcher A, Horn S, Golbe LI. Movement disorders and pregnancy: a review of the literature. Mov Disord. 2010 Apr 30; 25(6):665-71. PMID: 20437535.
      View in: PubMed
    44. Waubant E, Chabas D, Okuda DT, Glenn O, Mowry E, Henry RG, Strober JB, Soares B, Wintermark M, Pelletier D. Difference in disease burden and activity in pediatric patients on brain magnetic resonance imaging at time of multiple sclerosis onset vs adults. Arch Neurol. 2009 Aug; 66(8):967-71. PMID: 19667217.
      View in: PubMed
    45. Mowry E, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D. Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures. Neurology. 2009 May 19; 72(20):1760-5. PMID: 19451531; PMCID: PMC2683738.
    46. Mowry E, Pesic M, Grimes B, Deen SR, Bacchetti P, Waubant E. Clinical predictors of early second event in patients with clinically isolated syndrome. J Neurol. 2009 Jul; 256(7):1061-6. PMID: 19252775; PMCID: PMC2708331.
    47. Mowry E, Pesic M, Grimes B, Deen S, Bacchetti P, Waubant E. Demyelinating events in early multiple sclerosis have inherent severity and recovery. Neurology. 2009 Feb 17; 72(7):602-8. PMID: 19221292; PMCID: PMC2677540.
    48. Okuda DT, Mowry E, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology. 2009 Mar 03; 72(9):800-5. PMID: 19073949.
      View in: PubMed
    49. Mowry E, Deen S, Malikova I, Pelletier J, Bacchetti P, Waubant E. The onset location of multiple sclerosis predicts the location of subsequent relapses. J Neurol Neurosurg Psychiatry. 2009 Apr; 80(4):400-3. PMID: 19066192.
      View in: PubMed
    50. Chabas D, Castillo-Trivino T, Mowry E, Strober JB, Glenn OA, Waubant E. Vanishing MS T2-bright lesions before puberty: a distinct MRI phenotype? Neurology. 2008 Sep 30; 71(14):1090-3. PMID: 18824673.
      View in: PubMed
    51. Kranick SM, Mowry E, Rosenfeld MR. Progressive multifocal leukoencephalopathy after rituximab in a case of non-Hodgkin lymphoma. Neurology. 2007 Aug 14; 69(7):704-6. PMID: 17698796.
      View in: PubMed
    52. Mowry E, Woo JH, Ances BM. Technology insight: can neuroimaging provide insights into the role of ischemia in Baló's concentric sclerosis? Nat Clin Pract Neurol. 2007 Jun; 3(6):341-8. PMID: 17549060.
      View in: PubMed
    53. Mowry E, Woo JH, Ances BM. Baló's concentric sclerosis presenting as a stroke-like syndrome. Nat Clin Pract Neurol. 2007 Jun; 3(6):349-54. PMID: 17549061.
      View in: PubMed
    54. Mowry E, Balcer LJ, Galetta SL. Multiple sclerosis and the ophthalmologist. Compr Ophthalmol Update. 2007 Jan-Feb; 8(1):39-49. PMID: 17394758.
      View in: PubMed
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