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Emil Lin, PhD

Title(s)Professor Emeritus, Bioengineering
SchoolSchool of Pharmacy
Address1700 4th St.
San Francisco CA 94158
Phone415-476-5035
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    NON-CLINICAL ADME STUDIES
    NIH N01DA48842May 3, 2004 - May 2, 2008
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow: Executive Summary. Nutr Clin Pract. 2018 Oct; 33(5):594-596. Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30208264.
      View in: PubMed   Mentions:    Fields:    
    2. A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow. J Acad Nutr Diet. 2018 08; 118(8):1506-1525. Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30055713.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. A call to action for optimizing the electronic health record in the parenteral nutrition workflow. Am J Health Syst Pharm. 2018 Sep 15; 75(18):1400-1420. Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30065062.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow. Nutr Clin Pract. 2018 Oct; 33(5):e1-e21. Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30043492.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Nuclear F-actin and myosins drive relocalization of heterochromatic breaks. Nature. 2018 07; 559(7712):54-60. Caridi CP, D'Agostino C, Ryu T, Zapotoczny G, Delabaere L, Li X, Khodaverdian VY, Amaral N, Lin E, Rau AR, Chiolo I. PMID: 29925946.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    6. Microanalysis of the antiretroviral nevirapine in human hair from HIV-infected patients by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2011 Oct; 401(6):1923-33. Huang Y, Yang Q, Yoon K, Lei Y, Shi R, Gee W, Lin ET, Greenblatt RM, Gandhi M. PMID: 21847531.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    7. A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. BMC Clin Pharmacol. 2009 Aug 01; 9:13. Harris DS, Everhart T, Jacob P, Lin E, Mendelson JE, Jones RT. PMID: 19646280.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    8. Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice. Neurobiol Dis. 2009 Dec; 36(3):413-20. Li M, Huang Y, Ma AA, Lin E, Diamond MI. PMID: 19591939.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    9. Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease. J Med Chem. 2008 Nov 27; 51(22):7099-110. Zhang X, Tellew JE, Luo Z, Moorjani M, Lin E, Lanier MC, Chen Y, Williams JP, Saunders J, Lechner SM, Markison S, Joswig T, Petroski R, Piercey J, Kargo W, Malany S, Santos M, Gross RS, Wen J, Jalali K, O'Brien Z, Stotz CE, Crespo MI, Díaz JL, Slee DH. PMID: 18947224.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Sensitive analysis of anti-HIV drugs, efavirenz, lopinavir and ritonavir, in human hair by liquid chromatography coupled with tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Nov; 22(21):3401-9. Huang Y, Gandhi M, Greenblatt RM, Gee W, Lin ET, Messenkoff N. PMID: 18837069.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    11. Pharmacokinetics and tolerability of oseltamivir combined with probenecid. Antimicrob Agents Chemother. 2008 Sep; 52(9):3013-21. Holodniy M, Penzak SR, Straight TM, Davey RT, Lee KK, Goetz MB, Raisch DW, Cunningham F, Lin ET, Olivo N, Deyton LR. PMID: 18559644.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    12. Increased indomethacin dosing for persistent patent ductus arteriosus in preterm infants: a multicenter, randomized, controlled trial. J Pediatr. 2008 Aug; 153(2):183-9. Jegatheesan P, Ianus V, Buchh B, Yoon G, Chorne N, Ewig A, Lin E, Fields S, Moon-Grady A, Tacy T, Milstein J, Schreiber M, Padbury J, Clyman R. PMID: 18534218.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists. Bioorg Med Chem Lett. 2008 Mar 15; 18(6):1778-83. Zhang X, Rueter JK, Chen Y, Moorjani M, Lanier MC, Lin E, Gross RS, Tellew JE, Williams JP, Lechner SM, Markison S, Joswig T, Malany S, Santos M, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH. PMID: 18329269.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy. J Med Chem. 2008 Feb 14; 51(3):400-6. Slee DH, Zhang X, Moorjani M, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Wen J, O'Brien Z, Saunders J. PMID: 18189346.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    15. Risk factors for persistent ductus arteriosus patency during indomethacin treatment. J Pediatr. 2007 Dec; 151(6):629-34. Chorne N, Jegatheesan P, Lin E, Shi R, Clyman RI. PMID: 18035143.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    16. Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice. J Biol Chem. 2007 Aug 03; 282(31):22765-74. Yang R, Wilcox DM, Haasch DL, Jung PM, Nguyen PT, Voorbach MJ, Doktor S, Brodjian S, Bush EN, Lin E, Jacobson PB, Collins CA, Landschulz KT, Trevillyan JM, Rondinone CM, Surowy TK. PMID: 17550900.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    17. Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metab Dispos. 2007 Jul; 35(7):1126-34. Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL. PMID: 17431031.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    18. Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metab Dispos. 2006 Jul; 34(7):1136-44. Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET. PMID: 16581945.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    19. Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. J Pharmacol Exp Ther. 2006 May; 317(2):732-8. Yu Z, Ng VY, Su P, Engler MM, Engler MB, Huang Y, Lin E, Kroetz DL. PMID: 16421287.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Dose-response effect of tetracyclines on cerebral matrix metalloproteinase-9 after vascular endothelial growth factor hyperstimulation. J Cereb Blood Flow Metab. 2006 Sep; 26(9):1157-64. Lee CZ, Yao JS, Huang Y, Zhai W, Liu W, Guglielmo BJ, Lin E, Yang GY, Young WL. PMID: 16395286.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    21. Liquid chromatographic tandem mass spectrometric assay for the uremic toxin 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in human plasma. Rapid Commun Mass Spectrom. 2006; 20(10):1611-4. Huang Y, Sun H, Frassetto L, Benet LZ, Lin ET. PMID: 16628600.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1). Pharmacogenet Genomics. 2005 Apr; 15(4):201-9. Fujita T, Brown C, Carlson EJ, Taylor T, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Fujita K, Castro R, Chen CW, Lin ET, Brett CM, Burchard EG, Ferrin TE, Huang CC, Leabman MK, Giacomini KM. PMID: 15864112.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    23. Relative bioavailability of ketoprofen 20% in a poloxamer-lecithin organogel. Am J Health Syst Pharm. 2004 Dec 01; 61(23):2541-4. Dowling TC, Arjomand M, Lin ET, Allen LV, McPherson ML. PMID: 15595229.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    24. Pharmacokinetics of quinacrine in the treatment of prion disease. BMC Infect Dis. 2004 Nov 29; 4:53. Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ. PMID: 15569390.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    25. 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. Nat Med. 2004 Jun; 10(6):638-42. Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S, Lin ET, Hatton D, Zucchi R, Grandy DK. PMID: 15146179.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    26. Liquid chromatographic-tandem mass spectrometric assay for the simultaneous determination of didanosine and stavudine in human plasma, bronchoalveolar lavage fluid, alveolar cells, peripheral blood mononuclear cells, seminal plasma, cerebrospinal fluid and tonsil tissue. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jan 05; 799(1):51-61. Huang Y, Zurlinden E, Lin E, Li X, Tokumoto J, Golden J, Murr A, Engstrom J, Conte J. PMID: 14659435.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    27. Effect of sex and AIDS status on the plasma and intrapulmonary pharmacokinetics of rifampicin. Clin Pharmacokinet. 2004; 43(6):395-404. Conte JE, Golden JA, Kipps JE, Lin ET, Zurlinden E. PMID: 15086276.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    28. Pharmacokinetics and subjective effects of sublingual buprenorphine, alone or in combination with naloxone: lack of dose proportionality. Clin Pharmacokinet. 2004; 43(5):329-40. Harris DS, Mendelson JE, Lin ET, Upton RA, Jones RT. PMID: 15080765.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    29. Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence. J Pharmacol Exp Ther. 2004 Feb; 308(2):512-20. Wang D, Raehal KM, Lin ET, Lowery JJ, Kieffer BL, Bilsky EJ, Sadée W. PMID: 14600246.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    30. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clin Pharmacol Ther. 2003 Nov; 74(5):487-98. Pauli-Magnus C, Feiner J, Brett C, Lin E, Kroetz DL. PMID: 14586389.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    31. A high-performance liquid chromatographic-tandem mass spectrometric method for the determination of cethromycin (ABT-773) in human plasma, bronchoalveolar lavage fluid, and alveolar cells. J Chromatogr Sci. 2003 Oct; 41(9):494-9. Ren Q, Conte JE, Zurlinden E, Lin ET. PMID: 14596787.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Intra- and interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor. Antimicrob Agents Chemother. 2003 Jul; 47(7):2351-3. Phan DD, Chin-Hong P, Lin ET, Anderle P, Sadee W, Guglielmo BJ. PMID: 12821497.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    33. A high-pressure liquid chromatographic-tandem mass spectrometric method for the determination of ethambutol in human plasma, bronchoalveolar lavage fluid, and alveolar cells. J Chromatogr Sci. 2002 Feb; 40(2):113-8. Conte JE, Lin E, Zhao Y, Zurlinden E. PMID: 11881704.
      View in: PubMed   Mentions: 3     Fields:    
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