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Systemic proportional pulse index is associated with incident probable dementia: a post-hoc analysis of the SPRINT-MIND trial in the United States. J Geriatr Neurol. 2026 Jul 01.
Mazimba S, Nyirenda N, Bolaji O, Ashur N, Stafford P, Phiri J, Kabwe JC, Kwon Y, Brewer LC, Chihota B, Mubanga M, Mohammed SF, Breathett K, Forde AT, Raju M, Akanksha A, Vidic A, Mehta N, Lin E, Bilchick KC, Saylor D, Johnson A, Addison D. PMID: 42621653; PMCID: PMC13488910.
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Estimated pulse wave velocity, dementia risk, and vascular aging phenotypes: a post-hoc analysis of the SPRINT-MIND trial in the United States. J Geriatr Neurol. 2026 Jun; 5(1):16-23.
Nyirenda N, Chihota B, Bolaji O, Forde AT, Stafford P, Ashur N, Bilchick KC, Phiri J, Kabwe JC, Brewer LC, Mubanga M, Mohammed SF, Breathett K, Raju M, Vidic A, Mehta N, Lin E, Saylor D, Addison D, Kwon Y, Mazimba S. PMID: 42621620; PMCID: PMC13488911.
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Pemigatinib for Unresectable or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor-2 Rearrangement: Results From the Phase III FIGHT-302 Trial. J Clin Oncol. 2026 Aug 10; 44(23):2187-2197.
Bekaii-Saab TS, Melisi D, Wilmink H, Garufi C, Tran N, Tortora G, De Braud F, Frodin JE, Lonardi S, Lin E, Babiker H, Lin B, Fornaro L, Muñoz Martín A, Bridgewater J, Knox JJ, De Vos-Geelen J, Scott-Brown M, Veronese L, Ioannidis S, Gilmartin A, Janik JE, Guo Y, Furuse J, Ioka T, Rimassa L, Vogel A. PMID: 42223137.
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Clinical Outcomes and Prognostic Features of Diffuse Hemispheric Glioma, H3 G34-Mutant: An International Multi-institutional Study. Clin Cancer Res. 2026 Jun 01; 32(11):2243-2254.
Crowell C, Mankuzhy NP, Bennett J, Bandopadhayay P, Sturm D, Green AL, Gupta T, Chatterjee A, Epari S, Chinnaswamy G, Prasad M, Patel SH, MacNeil M, Vanan MI, Larouche V, Renzi S, Jones J, Perreault S, Mata-Mbemba D, Sangatsuda Y, Yoshimoto K, Lin E, Feddersen C, Cruz O, Pavon-Mengual M, Vizzini O, Zápotocký M, Popovacki A, Klawinski D, Hansford JR, Schlosser MP, Omene E, Alexander KL, Satgunaseelan L, Williams A, Yao K, Ronsley R, Cheng S, Ludlow L, Eisenstat D, Khuong-Quang DA, Tabouret E, André N, Matheson K, Chan A, Lim-Fat MJ, Lapointe S, Cayrol R, Coleman C, Juretic N, McThenia S, Khan S, Wright-Nadkarni M, Salloum R, Galvin RT, Sener U, Hawkins C, Imber BS, Karajannis MA, Jones DTW, Ligon KL, Jabado N, Erker C. PMID: 41801141; PMCID: PMC13223545.
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HumansCells
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Trajectories in renal perfusion pressure during hemodynamically guided therapy are associated with worsening renal function and patient outcomes. J Cardiol. 2026 04; 87(4):314-322.
Lin E, Bilchick K, Mehta N, Kwon Y, Ilonze O, Breathett K, Phiri J, Ernest R, Vidic A, Kabwe J, Bolaji O, Bandaru J, Mubanga M, Krittanawong C, Ashur N, Mazimba S. PMID: 41349944.
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Humans
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Pharmacological considerations for next-generation protein therapeutics in cardiovascular disease. J Pharmacol Exp Ther. 2025 Dec; 392(12):103696.
Lin E, Momin N. PMID: 41478659; PMCID: PMC12799588.
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HumansAnimals
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Predicting outcomes in patients with pulmonary hypertension using right ventricular global longitudinal strain versus tricuspid annular plane systolic excursion (TAPSE) and fractional area change: a retrospective analysis. J Cardiovasc Imaging. 2025 Oct 30; 33(1):15.
Alturaif N, Lin E, Sundararaghavan A, Mercurio V, Wilkinson T, Hilton T, Ilonze O, Breathett K, Kabwe J, Phiri J, Graham B, Hilton JF, Mihalek A, Ashur N, Patterson D, Bilchick K, Mazimba S. PMID: 41168886; PMCID: PMC12573895.
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1
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Semi-supervised Learning for Generalizable Intracranial Hemorrhage Detection and Segmentation. Radiol Artif Intell. 2024 05; 6(3):e230077.
Lin E, Yuh EL. PMID: 38446043; PMCID: PMC11140498.
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3 Fields:
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Humans
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Regional Blocks Benefit Patients Undergoing Bilateral Mastectomy with Immediate Implant-Based Reconstruction, Even After Discharge. Ann Surg Oncol. 2024 Jan; 31(1):316-324.
Tokita HK, Assel M, Simon BA, Lin E, Sarraf L, Masson G, Pilewskie M, Vingan P, Vickers A, Nelson JA. PMID: 37747581; PMCID: PMC11200308.
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1 Fields:
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Humans
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Beyond the AJR: Exploring the Yield of Head CT in Patients With Altered Mental Status. AJR Am J Roentgenol. 2023 Nov; 221(5):698.
Lin E, Yuh EL. PMID: 36883771.
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Computational Approaches for Acute Traumatic Brain Injury Image Recognition. Front Neurol. 2022; 13:791816.
Lin E, Yuh EL. PMID: 35370919; PMCID: PMC8964403.
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7
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Precision medicine in trauma: a transformational frontier in patient care, education, and research. Eur J Trauma Emerg Surg. 2022 Aug; 48(4):2607-2612.
Davis CS, Wilkinson KH, Lin E, Carpenter NJ, Georgeades C, Lomberk G, Urrutia R. PMID: 34786598; PMCID: PMC8594650.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK. Mol Cell. 2021 09 16; 81(18):3803-3819.e7.
Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, Lin E, Ketkar A, Eoff R, Xu ZG, Chen ZZ, Li HY, Lin HK. PMID: 34547240; PMCID: PMC8462099.
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46 Fields:
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HumansAnimalsCells
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Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor. Cancers (Basel). 2020 Jun 10; 12(6).
Novak CM, Horst EN, Lin E, Mehta G. PMID: 32532057; PMCID: PMC7352213.
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26
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Multicentre retrospective study of intravascular large B-cell lymphoma treated at academic institutions within the United States. Br J Haematol. 2019 07; 186(2):255-262.
Geer M, Roberts E, Shango M, Till BG, Smith SD, Abbas H, Hill BT, Kaplan J, Barr PM, Caimi P, Stephens DM, Lin E, Herrera AF, Rosenbaum E, Amengual JE, Boonstra PS, Devata S, Wilcox RA, Kaminski MS, Phillips TJ. PMID: 31044423; PMCID: PMC8989046.
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19 Fields:
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HumansCTClinical Trials
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A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow: Executive Summary. Nutr Clin Pract. 2018 Oct; 33(5):594-596.
Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C, American Society for Parenteral and Enteral Nutrition, Academy of Nutrition and Dietetics, American . PMID: 30208264.
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4 Fields:
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A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow. J Acad Nutr Diet. 2018 08; 118(8):1506-1525.
Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30055713.
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Humans
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A call to action for optimizing the electronic health record in the parenteral nutrition workflow. Am J Health Syst Pharm. 2018 Sep 15; 75(18):1400-1420.
Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C. PMID: 30065062.
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6 Fields:
Translation:
Humans
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A Call to Action for Optimizing the Electronic Health Record in the Parenteral Nutrition Workflow. Nutr Clin Pract. 2018 Oct; 33(5):e1-e21.
Vanek VW, Ayers P, Kraft M, Bouche JM, Do VT, Durham CW, Guenter P, Hoggle L, Kent S, Lin ET, Molinar LS, Plogsted SW, Poehls JM, Turner P, Van Way C, American Society for Parenteral and Enteral Nutrition, Academy of Nutrition and Dietetics, American . PMID: 30043492.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Nuclear F-actin and myosins drive relocalization of heterochromatic breaks. Nature. 2018 07; 559(7712):54-60.
Caridi CP, D'Agostino C, Ryu T, Zapotoczny G, Delabaere L, Li X, Khodaverdian VY, Amaral N, Lin E, Rau AR, Chiolo I. PMID: 29925946; PMCID: PMC6051730.
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PubMed Mentions:
202 Fields:
Translation:
AnimalsCells
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Microanalysis of the antiretroviral nevirapine in human hair from HIV-infected patients by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2011 Oct; 401(6):1923-33.
Huang Y, Yang Q, Yoon K, Lei Y, Shi R, Gee W, Lin ET, Greenblatt RM, Gandhi M. PMID: 21847531; PMCID: PMC3477620.
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27 Fields:
Translation:
Humans
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A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. BMC Clin Pharmacol. 2009 Aug 01; 9:13.
Harris DS, Everhart T, Jacob P, Lin E, Mendelson JE, Jones RT. PMID: 19646280; PMCID: PMC2731040.
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4 Fields:
Translation:
HumansCTClinical Trials
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Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice. Neurobiol Dis. 2009 Dec; 36(3):413-20.
Li M, Huang Y, Ma AA, Lin E, Diamond MI. PMID: 19591939.
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38 Fields:
Translation:
AnimalsCells
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Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease. J Med Chem. 2008 Nov 27; 51(22):7099-110.
Zhang X, Tellew JE, Luo Z, Moorjani M, Lin E, Lanier MC, Chen Y, Williams JP, Saunders J, Lechner SM, Markison S, Joswig T, Petroski R, Piercey J, Kargo W, Malany S, Santos M, Gross RS, Wen J, Jalali K, O'Brien Z, Stotz CE, Crespo MI, Díaz JL, Slee DH. PMID: 18947224.
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2 Fields:
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HumansAnimalsCells
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Sensitive analysis of anti-HIV drugs, efavirenz, lopinavir and ritonavir, in human hair by liquid chromatography coupled with tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Nov; 22(21):3401-9.
Huang Y, Gandhi M, Greenblatt RM, Gee W, Lin ET, Messenkoff N. PMID: 18837069; PMCID: PMC2669487.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Pharmacokinetics and tolerability of oseltamivir combined with probenecid. Antimicrob Agents Chemother. 2008 Sep; 52(9):3013-21.
Holodniy M, Penzak SR, Straight TM, Davey RT, Lee KK, Goetz MB, Raisch DW, Cunningham F, Lin ET, Olivo N, Deyton LR. PMID: 18559644; PMCID: PMC2533494.
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26 Fields:
Translation:
Humans
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Increased indomethacin dosing for persistent patent ductus arteriosus in preterm infants: a multicenter, randomized, controlled trial. J Pediatr. 2008 Aug; 153(2):183-9.
Jegatheesan P, Ianus V, Buchh B, Yoon G, Chorne N, Ewig A, Lin E, Fields S, Moon-Grady A, Tacy T, Milstein J, Schreiber M, Padbury J, Clyman R. PMID: 18534218.
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13 Fields:
Translation:
Humans
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2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents. J Med Chem. 2008 Mar 27; 51(6):1719-29.
Slee DH, Chen Y, Zhang X, Moorjani M, Lanier MC, Lin E, Rueter JK, Williams JP, Lechner SM, Markison S, Malany S, Santos M, Gross RS, Jalali K, Sai Y, Zuo Z, Yang C, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J. PMID: 18307292.
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7 Fields:
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HumansAnimalsCells
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2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 2. Reduction of hERG activity, observed species selectivity, and structure-activity relationships. J Med Chem. 2008 Mar 27; 51(6):1730-9.
Slee DH, Moorjani M, Zhang X, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Jalali K, Sai Y, Zuo Z, Yang C, Wen J, O'Brien Z, Petroski R, Saunders J. PMID: 18307293.
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3 Fields:
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HumansAnimalsCells
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Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists. Bioorg Med Chem Lett. 2008 Mar 15; 18(6):1778-83.
Zhang X, Rueter JK, Chen Y, Moorjani M, Lanier MC, Lin E, Gross RS, Tellew JE, Williams JP, Lechner SM, Markison S, Joswig T, Malany S, Santos M, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH. PMID: 18329269.
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4 Fields:
Translation:
HumansAnimalsCells
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Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy. J Med Chem. 2008 Feb 14; 51(3):400-6.
Slee DH, Zhang X, Moorjani M, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Wen J, O'Brien Z, Saunders J. PMID: 18189346.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Risk factors for persistent ductus arteriosus patency during indomethacin treatment. J Pediatr. 2007 Dec; 151(6):629-34.
Chorne N, Jegatheesan P, Lin E, Shi R, Clyman RI. PMID: 18035143.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice. J Biol Chem. 2007 Aug 03; 282(31):22765-74.
Yang R, Wilcox DM, Haasch DL, Jung PM, Nguyen PT, Voorbach MJ, Doktor S, Brodjian S, Bush EN, Lin E, Jacobson PB, Collins CA, Landschulz KT, Trevillyan JM, Rondinone CM, Surowy TK. PMID: 17550900.
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34 Fields:
Translation:
AnimalsCells
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Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metab Dispos. 2007 Jul; 35(7):1126-34.
Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL. PMID: 17431031.
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PubMed Mentions:
84 Fields:
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HumansAnimalsCells
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Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metab Dispos. 2006 Jul; 34(7):1136-44.
Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET. PMID: 16581945.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. J Pharmacol Exp Ther. 2006 May; 317(2):732-8.
Yu Z, Ng VY, Su P, Engler MM, Engler MB, Huang Y, Lin E, Kroetz DL. PMID: 16421287.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Dose-response effect of tetracyclines on cerebral matrix metalloproteinase-9 after vascular endothelial growth factor hyperstimulation. J Cereb Blood Flow Metab. 2006 Sep; 26(9):1157-64.
Lee CZ, Yao JS, Huang Y, Zhai W, Liu W, Guglielmo BJ, Lin E, Yang GY, Young WL. PMID: 16395286.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Liquid chromatographic tandem mass spectrometric assay for the uremic toxin 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in human plasma. Rapid Commun Mass Spectrom. 2006; 20(10):1611-4.
Huang Y, Sun H, Frassetto L, Benet LZ, Lin ET. PMID: 16628600.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1). Pharmacogenet Genomics. 2005 Apr; 15(4):201-9.
Fujita T, Brown C, Carlson EJ, Taylor T, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Fujita K, Castro R, Chen CW, Lin ET, Brett CM, Burchard EG, Ferrin TE, Huang CC, Leabman MK, Giacomini KM. PMID: 15864112.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Relative bioavailability of ketoprofen 20% in a poloxamer-lecithin organogel. Am J Health Syst Pharm. 2004 Dec 01; 61(23):2541-4.
Dowling TC, Arjomand M, Lin ET, Allen LV, McPherson ML. PMID: 15595229.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Pharmacokinetics of quinacrine in the treatment of prion disease. BMC Infect Dis. 2004 Nov 29; 4:53.
Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ. PMID: 15569390; PMCID: PMC535929.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. Nat Med. 2004 Jun; 10(6):638-42.
Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S, Lin ET, Hatton D, Zucchi R, Grandy DK. PMID: 15146179.
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PubMed Mentions:
160 Fields:
Translation:
HumansAnimalsCells
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Liquid chromatographic-tandem mass spectrometric assay for the simultaneous determination of didanosine and stavudine in human plasma, bronchoalveolar lavage fluid, alveolar cells, peripheral blood mononuclear cells, seminal plasma, cerebrospinal fluid and tonsil tissue. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jan 05; 799(1):51-61.
Huang Y, Zurlinden E, Lin E, Li X, Tokumoto J, Golden J, Murr A, Engstrom J, Conte J. PMID: 14659435.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Pharmacokinetics and subjective effects of sublingual buprenorphine, alone or in combination with naloxone: lack of dose proportionality. Clin Pharmacokinet. 2004; 43(5):329-40.
Harris DS, Mendelson JE, Lin ET, Upton RA, Jones RT. PMID: 15080765.
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PubMed Mentions:
32 Fields:
Translation:
HumansCTClinical Trials
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Effect of sex and AIDS status on the plasma and intrapulmonary pharmacokinetics of rifampicin. Clin Pharmacokinet. 2004; 43(6):395-404.
Conte JE, Golden JA, Kipps JE, Lin ET, Zurlinden E. PMID: 15086276.
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25 Fields:
Translation:
HumansCTClinical Trials
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Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence. J Pharmacol Exp Ther. 2004 Feb; 308(2):512-20.
Wang D, Raehal KM, Lin ET, Lowery JJ, Kieffer BL, Bilsky EJ, Sadée W. PMID: 14600246.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clin Pharmacol Ther. 2003 Nov; 74(5):487-98.
Pauli-Magnus C, Feiner J, Brett C, Lin E, Kroetz DL. PMID: 14586389.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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A high-performance liquid chromatographic-tandem mass spectrometric method for the determination of cethromycin (ABT-773) in human plasma, bronchoalveolar lavage fluid, and alveolar cells. J Chromatogr Sci. 2003 Oct; 41(9):494-9.
Ren Q, Conte JE, Zurlinden E, Lin ET. PMID: 14596787.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Intra- and interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor. Antimicrob Agents Chemother. 2003 Jul; 47(7):2351-3.
Phan DD, Chin-Hong P, Lin ET, Anderle P, Sadee W, Guglielmo BJ. PMID: 12821497; PMCID: PMC161865.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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A high-pressure liquid chromatographic-tandem mass spectrometric method for the determination of ethambutol in human plasma, bronchoalveolar lavage fluid, and alveolar cells. J Chromatogr Sci. 2002 Feb; 40(2):113-8.
Conte JE, Lin E, Zhao Y, Zurlinden E. PMID: 11881704.
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PubMed Mentions:
5 Fields: