Emily Blythe, PhD

Title(s)Postdoctoral Scholar, Psychiatry
SchoolSchool of Medicine
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Effects of GPCR trafficking on the spatiotemporal control of signaling
    NIH F32CA260118Feb 1, 2021 - Jan 31, 2024
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Profiling the proximal proteome of the activated μ-opioid receptor. Nat Chem Biol. 2024 Mar 25. Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. PMID: 38528119.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    2. β-Arrestin-independent endosomal cAMP signaling by a polypeptide hormone GPCR. Nat Chem Biol. 2024 Mar; 20(3):323-332. Blythe EE, von Zastrow M. PMID: 37749347; PMCID: PMC10907292.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    3. State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides. Cell. 2022 10 13; 185(21):3950-3965.e25. Dai SA, Hu Q, Gao R, Blythe EE, Touhara KK, Peacock H, Zhang Z, von Zastrow M, Suga H, Shokat KM. PMID: 36170854; PMCID: PMC9747239.
      View in: PubMed   Mentions: 8     Fields:    
    4. Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing. Structure. 2019 12 03; 27(12):1820-1829.e4. Blythe EE, Gates SN, Deshaies RJ, Martin A. PMID: 31623962; PMCID: PMC6929323.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    5. Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2. J Biol Chem. 2017 07 28; 292(30):12516-12527. Xu ER, Blythe EE, Fischer G, Hyvönen M. PMID: 28584056; PMCID: PMC5535026.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    6. Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy. Proc Natl Acad Sci U S A. 2017 05 30; 114(22):E4380-E4388. Blythe EE, Olson KC, Chau V, Deshaies RJ. PMID: 28512218; PMCID: PMC5465906.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    7. Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor. Mol Cell Proteomics. 2016 09; 15(9):2970-86. Xue L, Blythe EE, Freiberger EC, Mamrosh JL, Hebert AS, Reitsma JM, Hess S, Coon JJ, Deshaies RJ. PMID: 27406709; PMCID: PMC5013311.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    8. An unusual pattern of ligand-receptor interactions for the α7 nicotinic acetylcholine receptor, with implications for the binding of varenicline. Mol Pharmacol. 2013 Aug; 84(2):201-7. Van Arnam EB, Blythe EE, Lester HA, Dougherty DA. PMID: 23680636; PMCID: PMC3716316.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
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