Ernest Lee, MD, PhD

Title(s)RESIDENT PHYSICIAN, Dermatology
SchoolSchool of Medicine
AddressLocation Required, #001
Pronounshe/him/his
ORCID ORCID Icon0000-0001-5144-2552 Additional info
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    Collapse Biography 
    Collapse Education and Training
    California Institute of TechnologyBS2012Physics
    University of California, Los AngelesPhD2018Bioengineering
    David Geffen School of Medicine at UCLAMD2020Medicine
    Cedars-Sinai Medical CenterInternship2021Internal Medicine
    University of California, San FranciscoResidency2024Dermatology
    Collapse Awards and Honors
    2021Forbes 30 under 30 in Science
    UCLA2020Emil Bogen Research Prize
    UCLA2019Alpha Omega Alpha Honor Society, Junior Member
    UCLA2019Edward K. Rice Outstanding Doctoral Student Award
    UCLA2018Department of Bioengineering Outstanding PhD Student Award
    UCLA2017National Psoriasis Foundation Early Career Research Grant
    UCLA2015Hertz Foundation Graduate Fellowship Finalist

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sweet syndrome in a patient with rectal adenocarcinoma and HIV following neoadjuvant chemoradiation. JAAD Case Rep. 2024 Jan; 43:72-75. Wilkerson K, Bradley FE, Lee EY, Cohen JN, Chang AY. PMID: 38234372; PMCID: PMC10793161.
      View in: PubMed   Mentions:
    2. Excess psoriasis and psoriatic arthritis mortality during the COVID-19 pandemic in the United States: A nationwide population-based study from 2010 to 2021. J Eur Acad Dermatol Venereol. 2023 Jun; 37(6):1221-1227. Liu Y, He X, Lee EY, Lv F, Yao L, Meng Q, Zhang L, Ng WH, Zhang Y, Elias PM, Man M, Yeo YH, Li Z. PMID: 36808772.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    3. Severe recurrence of reactive infectious mucocutaneous eruption with extensive ocular involvement in an adult due to SARS-CoV-2. JAAD Case Rep. 2023 Jun; 36:1-3. Wu D, Lee EY, Lifton J, Zullo SW, Seiger K, Nadadur R, Fox LP, Escobar DJ, Dobry AS, Yung M, Kangelaris KN, Arakaki RY. PMID: 36819988; PMCID: PMC9931421.
      View in: PubMed   Mentions:
    4. Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity. Front Cell Infect Microbiol. 2022; 12:884065. Grando K, Nicastro LK, Tursi SA, De Anda J, Lee EY, Wong GCL, Tükel Ç. PMID: 35646719; PMCID: PMC9131096.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    5. Histidine-Mediated Ion Specific Effects Enable Salt Tolerance of a Pore-Forming Marine Antimicrobial Peptide. Angew Chem Int Ed Engl. 2022 06 20; 61(25):e202108501. Xian W, Hennefarth MR, Lee MW, Do T, Lee EY, Alexandrova AN, Wong GCL. PMID: 35352449; PMCID: PMC9189074.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    6. Quantitative readability analysis of online patient educational materials for dermatofibrosarcoma protuberans. Int J Dermatol. 2022 05; 61(5):e196-e197. Kirchner A, Patel M, Kulkarni V, Usman A, Lee EY. PMID: 34165781.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Readability assessment of patient-facing online educational content for pyoderma gangrenosum. J Am Acad Dermatol. 2022 05; 86(5):1127-1128. Kirchner A, Kulkarni V, Rajkumar J, Usman A, Hassan S, Lee EY. PMID: 33882279.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Lee EY, Chan LC, Wang H, Lieng J, Hung M, Srinivasan Y, Wang J, Waschek JA, Ferguson AL, Lee KF, Yount NY, Yeaman MR, Wong GCL. PMID: 33372152; PMCID: PMC7817161.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    9. Ocular lichen planus treated with lifitegrast. Int J Dermatol. 2021 Jun; 60(6):e231-e233. Lee EY, Arzeno J, Ni C, Holland V. PMID: 32989726.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Discovery of Novel Type II Bacteriocins Using a New High-Dimensional Bioinformatic Algorithm. Front Immunol. 2020; 11:1873. Yount NY, Weaver DC, de Anda J, Lee EY, Lee MW, Wong GCL, Yeaman MR. PMID: 33013838; PMCID: PMC7494827.
      View in: PubMed   Mentions: 7     Fields:    
    11. Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation. Front Immunol. 2020; 11:1629. Lee EY, Srinivasan Y, de Anda J, Nicastro LK, Tükel Ç, Wong GCL. PMID: 32849553; PMCID: PMC7412598.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    12. Standing electric scooter injuries: Impact on a community. Am J Surg. 2021 01; 221(1):227-232. Bloom MB, Noorzad A, Lin C, Little M, Lee EY, Margulies DR, Torbati SS. PMID: 32778397; PMCID: PMC7933485.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    13. Machine learning for precision dermatology: Advances, opportunities, and outlook. J Am Acad Dermatol. 2021 May; 84(5):1458-1459. Lee EY, Maloney NJ, Cheng K, Bach DQ. PMID: 32645400; PMCID: PMC8023050.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Telehealth Solutions for In-hospital Communication with Patients Under Isolation During COVID-19. West J Emerg Med. 2020 Jun 23; 21(4):801-806. Fang J, Liu YT, Lee EY, Yadav K. PMID: 32726245; PMCID: PMC7390554.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsPHPublic Health
    15. Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1. ACS Infect Dis. 2020 05 08; 6(5):1204-1213. Dishman AF, Lee MW, de Anda J, Lee EY, He J, Huppler AR, Wong GCL, Volkman BF. PMID: 32243126; PMCID: PMC7258946.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    16. Circulating biomarkers predictive of tumor response to cancer immunotherapy. Expert Rev Mol Diagn. 2019 10; 19(10):895-904. Lee EY, Kulkarni RP. PMID: 31469965; PMCID: PMC6773262.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    17. Improved prediction of HIT in the SICU using an improved model of the Warkentin 4-T system: 3-T. Am J Surg. 2020 01; 219(1):54-57. Bloom MB, Johnson J, Volod O, Lee EY, White T, Margulies DR. PMID: 31400811; PMCID: PMC6917902.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis. Nat Commun. 2019 05 01; 10(1):1731. Lande R, Lee EY, Palazzo R, Marinari B, Pietraforte I, Santos GS, Mattenberger Y, Spadaro F, Stefanantoni K, Iannace N, Dufour AM, Falchi M, Bianco M, Botti E, Bianchi L, Alvarez M, Riccieri V, Truchetet ME, C L Wong G, Chizzolini C, Frasca L. PMID: 31043596; PMCID: PMC6494823.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    19. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. 2019 05; 569(7755):236-240. Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. PMID: 31043745; PMCID: PMC6716525.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    20. Off-label studies on apremilast in dermatology: a review. J Dermatolog Treat. 2020 Mar; 31(2):131-140. Maloney NJ, Zhao J, Tegtmeyer K, Lee EY, Cheng K. PMID: 30935262; PMCID: PMC6774908.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    21. Unifying structural signature of eukaryotic α-helical host defense peptides. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6944-6953. Yount NY, Weaver DC, Lee EY, Lee MW, Wang H, Chan LC, Wong GCL, Yeaman MR. PMID: 30877253; PMCID: PMC6452647.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    22. Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9. Nat Commun. 2019 03 04; 10(1):1012. Lee EY, Zhang C, Di Domizio J, Jin F, Connell W, Hung M, Malkoff N, Veksler V, Gilliet M, Ren P, Wong GCL. PMID: 30833557; PMCID: PMC6399285.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    23. Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly. Curr Opin Colloid Interface Sci. 2018 Nov; 38:204-213. Lee MW, Lee EY, Ferguson AL, Wong GCL. PMID: 31093008; PMCID: PMC6513345.
      View in: PubMed   Mentions: 9  
    24. What Can Pleiotropic Proteins in Innate Immunity Teach Us about Bioconjugation and Molecular Design? Bioconjug Chem. 2018 07 18; 29(7):2127-2139. Lee MW, Lee EY, Wong GCL. PMID: 29771496; PMCID: PMC6540093.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    25. Multigenerational memory and adaptive adhesion in early bacterial biofilm communities. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4471-4476. Lee CK, de Anda J, Baker AE, Bennett RR, Luo Y, Lee EY, Keefe JA, Helali JS, Ma J, Zhao K, Golestanian R, O'Toole GA, Wong GCL. PMID: 29559526; PMCID: PMC5924909.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    26. Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors. Sci Rep. 2018 03 05; 8(1):4032. Takahashi T, Kulkarni NN, Lee EY, Zhang LJ, Wong GCL, Gallo RL. PMID: 29507358; PMCID: PMC5838106.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    27. Modulation of toll-like receptor signaling by antimicrobial peptides. Semin Cell Dev Biol. 2019 04; 88:173-184. Lee EY, Lee MW, Wong GCL. PMID: 29432957; PMCID: PMC6087683.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    28. Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission. ACS Cent Sci. 2017 Nov 22; 3(11):1156-1167. Lee MW, Lee EY, Lai GH, Kennedy NW, Posey AE, Xian W, Ferguson AL, Hill RB, Wong GCL. PMID: 29202017; PMCID: PMC5704292.
      View in: PubMed   Mentions: 15  
    29. What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning? Interface Focus. 2017 Dec 06; 7(6):20160153. Lee EY, Lee MW, Fulan BM, Ferguson AL, Wong GCL. PMID: 29147555; PMCID: PMC5665795.
      View in: PubMed   Mentions: 45  
    30. Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation. ACS Nano. 2017 12 26; 11(12):12145-12155. Lee EY, Takahashi T, Curk T, Dobnikar J, Gallo RL, Wong GCL. PMID: 29016111; PMCID: PMC5936640.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    31. High-Speed "4D" Computational Microscopy of Bacterial Surface Motility. ACS Nano. 2017 09 26; 11(9):9340-9351. de Anda J, Lee EY, Lee CK, Bennett RR, Ji X, Soltani S, Harrison MC, Baker AE, Luo Y, Chou T, O'Toole GA, Armani AM, Golestanian R, Wong GCL. PMID: 28836761; PMCID: PMC5978429.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    32. Machine learning-enabled discovery and design of membrane-active peptides. Bioorg Med Chem. 2018 06 01; 26(10):2708-2718. Lee EY, Wong GCL, Ferguson AL. PMID: 28728899; PMCID: PMC5758442.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    33. A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity. J Innate Immun. 2017; 9(5):456-463. Stolzenberg E, Berry D, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA. PMID: 28651250; PMCID: PMC5865636.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    34. Direct Antimicrobial Activity of IFN-β. J Immunol. 2017 05 15; 198(10):4036-4045. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM. PMID: 28411186; PMCID: PMC5469413.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    35. Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9. PLoS Pathog. 2017 Apr; 13(4):e1006315. Tursi SA, Lee EY, Medeiros NJ, Lee MH, Nicastro LK, Buttaro B, Gallucci S, Wilson RP, Wong GCL, Tükel Ç. PMID: 28410407; PMCID: PMC5406031.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    36. Mapping membrane activity in undiscovered peptide sequence space using machine learning. Proc Natl Acad Sci U S A. 2016 11 29; 113(48):13588-13593. Lee EY, Fulan BM, Wong GC, Ferguson AL. PMID: 27849600; PMCID: PMC5137689.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    37. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog. 2016 06; 12(6):e1005705. Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. PMID: 27355424; PMCID: PMC4927120.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    38. Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures. Langmuir. 2016 Mar 15; 32(10):2450-7. Sankhagowit S, Lee EY, Wong GC, Malmstadt N. PMID: 26866900; PMCID: PMC6559366.
      View in: PubMed   Mentions: 9     Fields:    
    39. A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes. Adv Colloid Interface Sci. 2016 06; 232:17-24. Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GCL. PMID: 26956527; PMCID: PMC6519935.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
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