Eunsol Yang, PhD, PharmD

Photo of Eunsol Yang, PhD, PharmD
Title(s)Assistant Researcher, Bioengineering
SchoolSchool of Pharmacy
Address1700 4th Street, #512
San Francisco CA 94158
PronounsShe/Her/Hers
ORCID ORCID Icon0000-0003-2581-349X Additional info
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    Collapse Overview 
    Collapse overview
    My research integrates multi-dimensional data into computational, model-informed approaches to optimize therapies across the drug lifecycle—from development to real-world use. Focusing on tuberculosis, type 2 diabetes, and drug repurposing, I develop translational frameworks to guide rational dose selection and regimen design and characterize patient heterogeneity to inform evidence-based treatment strategies. My goal is to generate clinically actionable, data-driven insights that enable treatment optimization—delivering “the right drug, at the right dose, to the right patient”—and ultimately advance human health.

    Collapse Biography 
    Collapse education and training
    Seoul National UniversityPhD02/2022Clinical Pharmacology
    Korea UniversityPharmD02/2018Pharmacy
    Collapse awards and honors
    American Society for Clinical Pharmacology and Therapeutics2024Presidential Trainee Awards

    Collapse Research 
    Collapse Featured Publications
    Collapse research activities and funding
    Characterizing patient heterogeneity in longitudinal glycemic outcomes in youth-onset type 2 diabetes to guide optimized treatment
    UCSF Mary Anne Koda-Kimble Seed Award for Innovation May 1, 2026 - Jun 1, 2027
    Role: Principal Investigator
    Protocol to review available pharmacokinetic evidence and models to inform updated dosing guidance of first-line medicines
    World Health Organization CA-0249985Nov 15, 2024 - Jul 31, 2025
    Role: Co-Investigator
    Evaluation of TB006 for the treatment of Glioblastoma
    The Ben & Catherine Ivy Foundation A144180Aug 1, 2024 - Jul 31, 2026
    Role: Co-Investigator
    Artificial intelligence-based methods to predict disease progression in youth with type 2 diabetes: a digital twin study
    American Diabetes Association 7-24-ICTST2DY-05Jul 1, 2024 - Jun 30, 2026
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Exploratory Evaluation of Solanidine as an Endogenous Marker for CYP2D6-Mediated Drug-Drug-Gene Interactions of Venlafaxine in Koreans. Clin Transl Sci. 2026 May; 19(5):e70564. Bae S, Lee GY, Yang E, Chae W, Yu KS, Cho JY, Kim A, Gu N, Lee S. PMID: 42026020; PMCID: PMC13106024.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Tuberculosis Disease Severity Assessment Using Clinical Variables and Radiology Enabled by Artificial Intelligence. J Infect Dis. 2026 Apr 16. Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, Grinev A, Xu AY, Yang E, Velásquez GE, Harrison L, Rosenthal A, Savic RM, Jacobson KR, Farhat MR. PMID: 41989328.
      View in: PubMed   Mentions:    Fields:    
    3. Pharmacokinetics and Dose Optimization of Ethambutol in Children on First-line Antituberculosis Therapy: An Individual Patient Data Meta-Analysis. J Infect Dis. 2026 Mar 30. Chung TK, Yang E, Shin M, Solans BP, Zhou X, Hwang S, Yoon MC, Purohit D, Yang D, Mouksassi S, Béranger A, Bekker A, Kwara A, Panjasawatwong N, Savic RM. PMID: 41906661.
      View in: PubMed   Mentions:    Fields:    
    4. Pharmacokinetic and pharmacogenomic predictors of hepatotoxicity in the HIRIF trial for drug-susceptible tuberculosis. Clin Infect Dis. 2026 Mar 06. Yang E, Van Brantegem P, Peloquin CA, Brooks MB, Coit JM, Vargas Vásquez D, Sánchez Garavito E, Calderón RI, Jiménez J, Tintaya K, Garcia D, Osso E, Mackay EA, Platt G, Lecca L, Savic RM, Davies GR, Mitnick CD, Velásquez GE. PMID: 41789820.
      View in: PubMed   Mentions:    Fields:    
    5. Optimizing Venlafaxine Therapy in Pregnancy: A Maternal-Fetal PBPK Modeling Approach. Drug Des Devel Ther. 2025; 19:10367-10382. Choi SY, Yang E, Shin KH. PMID: 41312050; PMCID: PMC12649812.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Escitalopram Dose Optimization During Pregnancy: A PBPK Modeling Approach. Pharmaceutics. 2025 Oct 17; 17(10). Choi SY, Yang E, Shin KH. PMID: 41155976; PMCID: PMC12567279.
      View in: PubMed   Mentions: 1  
    7. Pharmacometabolomics uncovers key metabolic changes in the first-in-human study of β-lapachone derivative. Metabolomics. 2025 Aug 19; 21(5):122. Jang Y, Kang J, Li Y, Chae W, Yang E, Lee S, Cho JY. PMID: 40830312; PMCID: PMC12364990.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. ACTG A5409 (RAD-TB): Study protocol for a phase 2 randomized, adaptive, dose-ranging, open-label trial of novel regimens for the treatment of pulmonary tuberculosis. Trials. 2025 Aug 15; 26(1):291. Harrison LJ, Velásquez GE, Kempker RR, Imperial MZ, Nuermberger E, Dorman SE, Ignatius E, Granche J, Phillips PPJ, Furin J, Yang E, Foley C, Chiambah S, Rogers R, Van Grack A, Roa J, Shenje J, Nerette S, Kanyama C, Kyeyune RB, Mendoza-Ticona A, Murtaugh W, Foraida S, Goth M, Vernon A, Dooley KE, Savic RM. PMID: 40817073; PMCID: PMC12357366.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    9. ACTG A5409 (RAD-TB): Study Protocol for a Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis. Res Sq. 2025 Mar 26. Harrison L, Velasquez GE, Kempker RR, Imperial MZ, Nuermberger E, Dorman SE, Ignatius E, Granche J, Phillips PP, Furin J, Yang E, Foley C, Chiambah S, Rogers R, Van Grack A, Roa J, Shenje J, Nerette S, Kanyama C, Kyeyune RB, Mendoza-Ticona A, Murtaugh W, Foraida S, Goth M, Vernon A, Dooley KE, Savic RM. PMID: 40195983; PMCID: PMC11975035.
      View in: PubMed   Mentions:
    10. Tuberculosis disease severity assessment using clinical variables and radiology enabled by artificial intelligence. medRxiv. 2025 Mar 21. Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, Grinev A, Xu AY, Yang E, Velásquez GE, Harrison L, Rosenthal A, Savic RM, Jacobson KR, Farhat MR. PMID: 39228708; PMCID: PMC11370523.
      View in: PubMed   Mentions: 1  
    11. Effect of SLC22A1 polymorphism on the pharmacokinetics of proguanil in Korean: A semi-physiologic population pharmacokinetic approach. Clin Transl Sci. 2024 Dec; 17(12):e70103. Khwarg J, Yang E, Park CS, Ji SC, Yu KS, Lee S. PMID: 39668580; PMCID: PMC11638344.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Population pharmacokinetic analysis of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in patients and healthy volunteers. CPT Pharmacometrics Syst Pharmacol. 2024 12; 13(12):2150-2158. Yang E, Hwang I, Ji SC, Kim J, Lee S. PMID: 39268835; PMCID: PMC11646930.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects. Clin Pharmacol Drug Dev. 2024 02; 13(2):128-133. Khwarg J, Chung WK, Lee S, Yang E, Ryu C, Lee DY, Lee MJ, Jang IJ, Yu KS, Lee S. PMID: 38156730.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Effects of food and ethnicity on the pharmacokinetics of venadaparib, a next-generation PARP inhibitor, in healthy Korean, Caucasian, and Chinese male subjects. Invest New Drugs. 2024 02; 42(1):80-88. Kim HC, Yang E, Lee S, Oh J, Lee M, Lee C, Ha KS, Lee WS, Jang IJ, Yu KS. PMID: 38099989; PMCID: PMC10891214.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed-release formulations. Br J Clin Pharmacol. 2023 Sep; 89(9):2877-2887. Park S, Yang E, Kim B, Kwon J, Jang IJ, Lee SH. PMID: 37170677.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects. Drug Des Devel Ther. 2023; 17:1115-1124. Kim HC, Yang E, Ban MS, Kim YK, Hong SH, Jung J, Jang IJ, Lee S. PMID: 37077412; PMCID: PMC10106809.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Prediction of gastric pH-mediated drug exposure using physiologically-based pharmacokinetic modeling: A case study of itraconazole. CPT Pharmacometrics Syst Pharmacol. 2023 06; 12(6):865-877. Yang E, Yu KS, Lee S. PMID: 36967484; PMCID: PMC10272297.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole. Clin Pharmacokinet. 2023 04; 62(4):599-608. Yang E, Ji SC, Jang IJ, Lee S. PMID: 36897544; PMCID: PMC10085907.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects. Pharmaceutics. 2023 Feb 07; 15(2). Oh J, Yang E, Jang IJ, Lee H, Yoo H, Chung JY, Lee S, Oh J. PMID: 36839870; PMCID: PMC9958674.
      View in: PubMed   Mentions: 5  
    20. Evaluation of food effects on the pharmacokinetics of Pelargonium sidoides and Coptis with each bioactive compound berberine and epicatechin after a single oral dose of an expectorant and antitussive agent UI026 in healthy subjects. Transl Clin Pharmacol. 2022 Mar; 30(1):49-56. Park Y, Jung W, Yang E, Nam KY, Bong WR, Kim J, Kim KY, Lee S, Cho JY, Hong JH, Kim J. PMID: 35419311; PMCID: PMC8979756.
      View in: PubMed   Mentions: 2  
    21. Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole. Br J Clin Pharmacol. 2022 07; 88(7):3288-3296. Yang E, Kim S, Kim B, Kim B, Kim Y, Park SS, Song GS, Yu KS, Jang IJ, Lee S. PMID: 35146797; PMCID: PMC9305887.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    22. Comparative Pharmacokinetics Between a Fixed-Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects. Clin Pharmacol Drug Dev. 2022 05; 11(5):615-622. Na JY, Yang E, Kim JH, Kwon IS, Jin EH, Yu KS, Kim J, Lee S, Hong JH. PMID: 34997835.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese. Clin Transl Sci. 2022 02; 15(2):490-500. Yang E, Sunwoo J, Huh KY, Kim YK, Lee S, Jang IJ, Yu KS. PMID: 34670008; PMCID: PMC8841444.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. A first-in-human study of KMRC011, a potential treatment for acute radiation syndrome, to explore tolerability, pharmacokinetics, and pharmacodynamics. Clin Transl Sci. 2021 11; 14(6):2161-2170. Yang E, Choi H, Park JS, Noh YW, Choi CM, Lee WJ, Ko JW, Kim J. PMID: 34080313; PMCID: PMC8604209.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    25. Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study. Drug Des Devel Ther. 2021; 15:651-658. Yang E, Yoo H, Jang IJ, Yu KS, Lee S. PMID: 33628012; PMCID: PMC7898221.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes. Transl Vis Sci Technol. 2020 05; 9(6):20. Kim HM, Ha S, Hong HK, Hwang Y, Kim P, Yang E, Chung JY, Park S, Park YJ, Park KH, Kim H, Woo SJ. PMID: 32821517; PMCID: PMC7409074.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    27. Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects. Transl Clin Pharmacol. 2019 Dec; 27(4):134-140. Yang E, Lee S, Lee H, Hwang I, Jang IJ, Yu KS, Lee S. PMID: 32095481; PMCID: PMC7032963.
      View in: PubMed   Mentions: 2  
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