Fanny Elahi, MD, PhD

Title(s)Research Associate, Neurology
SchoolSchool of Medicine
AddressLocation Required, #001
Phone415-476-6880
ORCID ORCID Icon0000-0003-4663-4992 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2018Behavioral Neurology
    University of California, Los AngelesResidency2015Neurology
    Icahn School of Medicine at Mount SinaiMD2011Medicine
    Oxford UniversityDPhil2008Neurogenetics
    Columbia UniversityBS2003Comparative Lit & Society
    Collapse Awards and Honors
    New Vision Research2019New Vision Investigator Award
    American Academy of Neurology2016  - 2018Research Fellowship in Behavioral Neurology
    Alpha Omega Alpha Honor Society2008Carolyn L. Kuckein research scholarship
    Medical Research Council, UK2004  - 2008MRC DPhil scholarship
    Northwick Park Institute for Medical Research 2004  - 2007NPIMR student scholarship
    The Royal Society, UK2003Royal Society student scholarship

    Collapse Overview 
    Collapse Overview
    Fanny Elahi is a board-certified neurologist with specific expertise in the evaluation and management of patients with cognitive and behavioral disorders due to degenerative brain diseases such as Alzheimer's disease and related disorders. She completed her bachelor's degree at Columbia University, her MD from Icahn School of Medicine, at Mount Sinai, and her DPhil from Oxford University. She pursued her residency in neurology at the University of California, Los Angeles and joined the University of California, San Francisco Memory and Aging Center in 2015 where she trained in neurodegenerative disorders prior to joining the faculty in the department of Neurology. Her research is focused on the identification of early biomarkers of degenerative brain disease with a particular interest in characterization of contributions of immune dysregulation and vascular disease to brain dysfunction, mood and cognitive changes, and ultimately progressive brain degeneration. Her work has been supported by the American Academy of Neurology in partnership with the Allergan foundation, the Alzheimer's Disease Research Center at the UCSF Memory and Aging Center, the National Institute of Neurological Disorders and Stroke, as well as philanthropic donations.

    Collapse Research 
    Collapse Research Activities and Funding
    A Precision Medicine Approach To Study Targetable Pathways in Vascular Dementia
    NIH IK2CX002180Jan 1, 2021 - Dec 31, 2026
    Role: Principal Investigator
    The Clinical Significance of Incidental White Matter Lesions on MRI Amongst a Diverse Population with Cognitive Complaints (INDEED)
    NIH/NINDS U19 NS120384Oct 1, 2020 - Sep 30, 2026
    Role: Co-Investigator
    Description: Subaward to investigate novel biomarkers of endothelial inflammation in a diverse cohort of 6000 individuals with white matter disease.
    New Approaches to Dementia Heterogeneity
    NIH/NIA P30 AG062422Sep 1, 2020 - May 31, 2024
    Role: Co-Investigator
    Description: Supplement associated with the CDA award (IK2 CX002180).
    Elucidating the role of placental growth factor in diffuse white matter disease
    NIH/NINDS R01 NS116990Feb 1, 2020 - Mar 31, 2023
    Role: Co-Investigator
    “Liquid biopsy” of white matter degeneration and bioenergetic failure in neurodegenerative disorders
    Larry L. Hillblom Foundation 2019-A-012-SUPJul 1, 2019 - Jun 30, 2021
    Role: Principal Investigator
    Multi-cellular exosome-based biomarkers to capture the dysfunction of the neurovascular unit in early-preclinical stages of AD-related brain degeneration
    Donors Cure Foundation CCAD201903Jun 1, 2019 - May 31, 2021
    Role: Principal Investigator
    Immunomodulation to promote cerebrovascular and cognitive health
    AHA / Allen Frontiers Group 62100829-138877Feb 1, 2019 - Jan 31, 2024
    Role: Co-Investigator
    Novel imaging and endothelial biomarkers of small vessel cerebrovascular disease
    NIH/NINDS UH3NS100608Sep 30, 2016 - Jun 30, 2021
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cerebral Small Vessel Disease-Related Dementia: More Questions Than Answers. Stroke. 2023 03; 54(3):648-660. Elahi FM, Wang MM, Meschia JF. PMID: 36848423.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Placental growth factor as a sensitive biomarker for vascular cognitive impairment. Alzheimers Dement. 2023 Feb 23. Hinman JD, Elahi F, Chong D, Radabaugh H, Ferguson A, Maillard P, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Wilcock D, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, DeCarli C, Kramer J. PMID: 36815663.
      View in: PubMed   Mentions:    Fields:    
    3. Immune cell counts in cerebrospinal fluid predict cognitive function in aging and neurodegenerative disease. Alzheimers Dement. 2023 Feb 15. Snyder A, Grant H, Chou A, Lindbergh CA, Kramer JH, Miller BL, Elahi FM. PMID: 36791265.
      View in: PubMed   Mentions:    Fields:    
    4. Blood-brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain. Alzheimer's & Dementia. 2022 Dec 20; 18(S6). Tabdili TY, Belmonte BK, Brathaban BN, Iorio IE, Park PR, VandeBunte VA, Casaletto CK, Kramer KJ, Akassoglou AK, Elahi EF. .
      View in: Publisher Site   Mentions:
    5. An introduction to therapeutic challenges of vascular cognitive impairment. Alzheimer's & Dementia. 2022 Dec 20; 18(S5). Elahi EF. .
      View in: Publisher Site   Mentions:
    6. Sex modifies the association between hippocampal blood flow and episodic memory in cognitively unimpaired individuals. Alzheimer's & Dementia. 2022 Dec 20; 18(S3). Brugulat-Serrat BA, Cobigo CY, Fonseca FC, Tsuei TT, Goldberger GL, Rosen RH, Kramer KJ, Elahi EF, Staffaroni SA, Casaletto CK. .
      View in: Publisher Site   Mentions:
    7. Real world clinical perspective on PDE5i utility in dementia. Alzheimer's & Dementia. 2022 Dec 20; 18(S10). Elahi EF. .
      View in: Publisher Site   Mentions:
    8. Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment. Cell. 2022 Dec 07. Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. PMID: 36516855.
      View in: PubMed   Mentions: 5     Fields:    
    9. Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia. Brain. 2022 11 21; 145(11):4080-4096. Younes K, Borghesani V, Montembeault M, Spina S, Mandelli ML, Welch AE, Weis E, Callahan P, Elahi FM, Hua AY, Perry DC, Karydas A, Geschwind D, Huang E, Grinberg LT, Kramer JH, Boxer AL, Rabinovici GD, Rosen HJ, Seeley WW, Miller ZA, Miller BL, Sturm VE, Rankin KP, Gorno-Tempini ML. PMID: 35731122.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology. Alzheimers Dement (Amst). 2022; 14(1):e12338. Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ. PMID: 35814617; PMCID: PMC9257197.
      View in: PubMed   Mentions:
    11. Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2022 Jun 16. Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, Chan JR, Green AJ. PMID: 35710320; PMCID: PMC9984688.
      View in: PubMed   Mentions: 1     Fields:    
    12. Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2022 Feb 01; 12(1):2008. Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 35105918; PMCID: PMC8807814.
      View in: PubMed   Mentions:    Fields:    
    13. CSF and plasma placental growth factor as a biomarker for small-vessel damage in VCID. Alzheimer's & Dementia. 2022 Feb 1; 17. Sudduth ST, Winder WZ, Elahi EF, Nelson NP, Jicha JG, Wilcock WD. .
      View in: Publisher Site   Mentions:
    14. Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology. Alzheimer's & Dementia. 2021 Dec 31; 17(S5). Abdelhak AA, Solomon SI, Saias SA, Montes MS, Cordano CC, Asken AB, Fonseca FC, Oertel OF, Arfanakis AK, Staffaroni SA, Geschwind GM, Elahi EF, Green GA. .
      View in: Publisher Site   Mentions:
    15. Plasma Biomarkers of Angiogenesis Related to Small Vessel Brain Disease in SPRINT. Innovation in Aging. 2021 Dec 17; 5(Suppl 1):667-667. Pajewski PN, Elahi EF, Ix IJ, Nasrallah NI, Hinman HJ, Launer LL, Williamson WJ, Wilcock WD. .
      View in: Publisher Site   Mentions:
    16. Plasma Biomarkers of Angiogenesis Related to Small Vessel Brain Disease in SPRINT. Innovation in Aging. 2021 Dec 17; 5(Suppl 1):670-671. Pajewski PN, Elahi EF, Ix IJ, Nasrallah NI, Hinman HJ, Launer LL, Williamson WJ, Wilcock WD. .
      View in: Publisher Site   Mentions:
    17. Retinal biomarkers predict future cognitive performance in progranulin-haploinsufficient frontotemporal dementia. Alzheimer's & Dementia. 2021 Dec 1; 17(S4). Oertel OF, Younes YK, Cobigo CY, Keihani KA, Fonseca FC, Bennett BD, Abdelhak AA, Saias SA, Montes MS, Chen CR, Cordano CC, Green GA, Elahi EF. .
      View in: Publisher Site   Mentions:
    18. Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT). Alzheimers Dement. 2022 08; 18(8):1472-1483. Pajewski NM, Elahi FM, Tamura MK, Hinman JD, Nasrallah IM, Ix JH, Miller LM, Launer LJ, Wright CB, Supiano MA, Lerner AJ, Sudduth TL, Killeen AA, Cheung AK, Reboussin DM, Wilcock DM, Williamson JD. PMID: 34786815; PMCID: PMC9110563.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    19. Interbatch Reliability of Blood-Based Cytokine and Chemokine Measurements in Community-Dwelling Older Adults: A Cross-Sectional Study. J Gerontol A Biol Sci Med Sci. 2021 10 13; 76(11):1954-1961. Lindbergh CA, Asken BM, Casaletto KB, Elahi FM, Goldberger LA, Fonseca C, You M, Apple AC, Staffaroni AM, Fitch R, Rivera Contreras W, Wang P, Karydas A, Kramer JH, Hillblom Aging Network. PMID: 34110415; PMCID: PMC8514070.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition. Geroscience. 2022 02; 44(1):25-37. Whitehead SN, Bruno A, Burns JM, Carmichael ST, Csiszar A, Edwards JD, Elahi FM, Faraco G, Gould DB, Gustafson DR, Hachinski V, Rosenberg G, Sorond FA, Shih AY, Tse KH, Ungvari Z, Wilcock DM, Zuloaga KL, Barone FC. PMID: 34606040; PMCID: PMC8488071.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2021 08 10; 11(1):16198. Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 34376699; PMCID: PMC8355229.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment. J Int Neuropsychol Soc. 2022 07; 28(6):588-599. Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB. PMID: 34158138; PMCID: PMC8692495.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    23. Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney. Alzheimers Dement. 2022 01; 18(1):178-190. Sexton CE, Anstey KJ, Baldacci F, Barnum CJ, Barron AM, Blennow K, Brodaty H, Burnham S, Elahi FM, Götz J, Jeon YH, Koronyo-Hamaoui M, Landau SM, Lautenschlager NT, Laws SM, Lipnicki DM, Lu H, Masters CL, Moyle W, Nakamura A, Pasinetti GM, Rao N, Rowe C, Sachdev PS, Schofield PR, Sigurdsson EM, Smith K, Srikanth V, Szoeke C, Tansey MG, Whitmer R, Whitmer R, Wilcock D, Wong TY, Bain LJ, Carrillo MC. PMID: 34058063; PMCID: PMC9396711.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers. Alzheimers Dement (Amst). 2021; 13(1):e12181. Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH. PMID: 34013017; PMCID: PMC8111703.
      View in: PubMed   Mentions: 6  
    25. APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults. Hippocampus. 2021 08; 31(8):845-857. Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH. PMID: 33835624; PMCID: PMC8295213.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Instrumental variable meta-analysis of aggregated randomized drug trial data for evaluating proposed target mechanisms. BMJ. 2021 02 25; 372:n346. Ackley SF, Elahi F, Glymour MM. PMID: 33632740.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis. BMJ. 2021 02 25; 372:n156. Ackley SF, Zimmerman SC, Brenowitz WD, Tchetgen Tchetgen EJ, Gold AL, Manly JJ, Mayeda ER, Filshtein TJ, Power MC, Elahi FM, Brickman AM, Glymour MM. PMID: 33632704; PMCID: PMC7905687.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    28. Pathophysiologic mechanisms of cerebral endotheliopathy and stroke due to Sars-CoV-2. J Cereb Blood Flow Metab. 2021 06; 41(6):1179-1192. Kakarla V, Kaneko N, Nour M, Khatibi K, Elahi F, Liebeskind DS, Hinman JD. PMID: 33530831; PMCID: PMC8142132.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols. Alzheimers Dement. 2021 04; 17(4):704-715. Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SM, MarkVCID Consortium. PMID: 33480172; PMCID: PMC8122220.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    30. Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage. J Alzheimers Dis. 2021; 80(1):471-474. Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB. PMID: 33612550.
      View in: PubMed   Mentions: 2     Fields:    
    31. An introduction to therapeutic approaches to vascular cognitive impairment. Cereb Circ Cogn Behav. 2021; 2:100033. Hainsworth AH, Elahi FM, Corriveau RA. PMID: 34950896; PMCID: PMC8661126.
      View in: PubMed   Mentions: 3  
    32. ß-amyloid and tau drive early Alzheimer’s disease decline while glucose hypometabolism drives late decline. Alzheimer's & Dementia. 2020 Dec 7; 16(S5). Hammond HT, Xing XX, W WD, Nho NK, Crane CP, Elahi EF, Ziegler ZD, Liang LG, Cheng CQ, Jacobs JN, Lin LA, Initiative IA. .
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    33. Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia. Alzheimer's & Dementia. 2020 Dec 7; 16(S5). Ljubenkov LP, Staffaroni SA, Casaletto CK, Rojas RJ, Vandevrede VL, Heuer HH, Elahi EF, Brushaber BD, Foroud FT, Forsberg FL, Karydas KA, Boeve BB, Rosen RH, Boxer BA, Kramer KJ, Investigators IA. .
      View in: Publisher Site   Mentions:
    34. Fluid biomarkers of Alzheimer’s disease in the Systolic Blood Pressure Intervention Trial. Alzheimer's & Dementia. 2020 Dec 7; 16(S5). Pajewski PN, Elahi EF, Ix IJ, Nasrallah NI, Reboussin RD, Tamura TM, Wright WC, Hinman HJ, Miller ML, Sudduth ST, Wilcock WD, Williamson WJ. .
      View in: Publisher Site   Mentions:
    35. Evaluation of polygenic risk scores for 17 cancer types in relation to cognitive decline in the UK Biobank. Alzheimer's & Dementia. 2020 Dec 7; 16(S10). Graff GR, Ackley AS, Romero RM, Zimmerman ZS, Elahi EF, Lu LK, Witte WJ, Glymour GM. .
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    36. Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF). Alzheimers Dement. 2021 04; 17(4):574-583. Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH. PMID: 33215852; PMCID: PMC8044003.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection. Stroke. 2021 01; 52(1):260-270. Kaneko N, Satta S, Komuro Y, Muthukrishnan SD, Kakarla V, Guo L, An J, Elahi F, Kornblum HI, Liebeskind DS, Hsiai T, Hinman JD. PMID: 33161843; PMCID: PMC7769899.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    38. Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults. J Int Neuropsychol Soc. 2021 04; 27(4):382-388. Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer JH, Hillblom Aging Network. PMID: 33050976; PMCID: PMC8026481.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Sex-related differences in the relationship between β-amyloid and cognitive trajectories in older adults. Neuropsychology. 2020 Nov; 34(8):835-850. Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH, Hillblom Aging Network. PMID: 33030915; PMCID: PMC7839841.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Editorial: Lipids in the Brain. Front Neurol. 2020; 11:712. Albi E, Alessenko AV, Elahi FM, Ledesma MD. PMID: 32765414; PMCID: PMC7380326.
      View in: PubMed   Mentions: 1  
    41. Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. J Gerontol A Biol Sci Med Sci. 2020 07 13; 75(8):1558-1565. Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH. PMID: 31549145; PMCID: PMC7457183.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    42. REM sleep is associated with white matter integrity in cognitively healthy, older adults. PLoS One. 2020; 15(7):e0235395. Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM. PMID: 32645032; PMCID: PMC7347149.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    43. β-amyloid and tau drive early Alzheimer's disease decline while glucose hypometabolism drives late decline. Commun Biol. 2020 07 06; 3(1):352. Hammond TC, Xing X, Wang C, Ma D, Nho K, Crane PK, Elahi F, Ziegler DA, Liang G, Cheng Q, Yanckello LM, Jacobs N, Lin AL. PMID: 32632135; PMCID: PMC7338410.
      View in: PubMed   Mentions: 28  Translation:Humans
    44. Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates. Am J Geriatr Psychiatry. 2020 09; 28(9):946-956. Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB, Hillblom Aging Network. PMID: 32527600; PMCID: PMC7484115.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. Brain Behav Immun. 2020 08; 88:699-710. Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH. PMID: 32387511; PMCID: PMC7416443.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    46. Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy. FASEB J. 2020 04; 34(4):5967-5974. Abner EL, Elahi FM, Jicha GA, Mustapic M, Al-Janabi O, Kramer JH, Kapogiannis D, Goetzl EJ. PMID: 32157747; PMCID: PMC7233139.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    47. The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases. Expert Rev Mol Diagn. 2020 04; 20(4):421-441. Baldacci F, Mazzucchi S, Della Vecchia A, Giampietri L, Giannini N, Koronyo-Hamaoui M, Ceravolo R, Siciliano G, Bonuccelli U, Elahi FM, Vergallo A, Lista S, Giorgi FS, Hampel H. PMID: 32066283; PMCID: PMC7445079.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    48. An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury. PLoS One. 2020; 15(1):e0227835. Altendahl M, Maillard P, Harvey D, Cotter D, Walters S, Wolf A, Singh B, Kakarla V, Azizkhanian I, Sheth SA, Xiao G, Fox E, You M, Leng M, Elashoff D, Kramer JH, Decarli C, Elahi F, Hinman JD. PMID: 31978079; PMCID: PMC6980497.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    49. Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease. Alzheimers Dement. 2020 04; 16(4):681-695. Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH. PMID: 31879236; PMCID: PMC7138729.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    50. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. 2020 01; 577(7790):399-404. Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. PMID: 31915375; PMCID: PMC7445078.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansCells
    51. Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage. J Alzheimers Dis. 2020; 78(1):265-276. Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB. PMID: 32986672; PMCID: PMC7727314.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    52. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimers Dement. 2020 01; 16(1):11-21. Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ, ARTFL/LEFFTDS consortium. PMID: 31914230; PMCID: PMC6842665.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    53. Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration. Alzheimers Dement. 2020 01; 16(1):91-105. Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K, ARTFL/LEFFTDS Study. PMID: 31914227; PMCID: PMC6953618.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    54. Acute Insulin Resistance and Rapid Alterations in Neuronal Derived Blood Exosome Concentration After Branched Endovascular Aortic Aneurysm Repair. Eur J Vasc Endovasc Surg. 2020 Mar; 59(3):457-463. Hiramoto JS, Elahi FM, Gasper WJ, Reilly LM, Chuter TA, Goetzl EJ. PMID: 31866237.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    55. Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. Stem Cells. 2020 01; 38(1):15-21. Elahi FM, Farwell DG, Nolta JA, Anderson JD. PMID: 31381842; PMCID: PMC7004029.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    56. STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p846-p847. Weiner-Light WS, Walters WS, Djukic DN, You YM, Cotter CD, Altendahl AM, Elahi EF, Staffaroni SA, Lindbergh LC, Kramer KJ, Casaletto CK. .
      View in: Publisher Site   Mentions:
    57. Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality. Alzheimers Dement. 2019 07; 15(7):907-916. Filshtein TJ, Brenowitz WD, Mayeda ER, Hohman TJ, Walter S, Jones RN, Elahi FM, Glymour MM. PMID: 31327391; PMCID: PMC7049165.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    58. Neuron-Derived Exosome Proteins May Contribute to Progression From Repetitive Mild Traumatic Brain Injuries to Chronic Traumatic Encephalopathy. Front Neurosci. 2019; 13:452. Goetzl EJ, Ledreux A, Granholm AC, Elahi FM, Goetzl L, Hiramoto J, Kapogiannis D. PMID: 31133789; PMCID: PMC6517542.
      View in: PubMed   Mentions: 22  
    59. A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure. Hum Brain Mapp. 2019 08 15; 40(12):3522-3533. Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH. PMID: 31062904; PMCID: PMC6693488.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    60. Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time. Front Aging Neurosci. 2019; 11:25. Bettcher BM, Neuhaus J, Wynn MJ, Elahi FM, Casaletto KB, Saloner R, Fitch R, Karydas A, Kramer JH. PMID: 30814948; PMCID: PMC6381047.
      View in: PubMed   Mentions: 23  
    61. Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials. Brain. 2019 02 01; 142(2):443-459. Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ. PMID: 30698757; PMCID: PMC6351779.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCTClinical Trials
    62. Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults. Neurobiol Aging. 2019 05; 77:13-19. Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH. PMID: 30772736; PMCID: PMC6486874.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    63. Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia. Alzheimers Dement (Amst). 2019 Dec; 11:61-66. Winston CN, Goetzl EJ, Schwartz JB, Elahi FM, Rissman RA. PMID: 31032394; PMCID: PMC6477776.
      View in: PubMed   Mentions: 37  
    64. Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury. FASEB J. 2019 04; 33(4):5082-5088. Goetzl EJ, Elahi FM, Mustapic M, Kapogiannis D, Pryhoda M, Gilmore A, Gorgens KA, Davidson B, Granholm AC, Ledreux A. PMID: 30605353; PMCID: PMC6436652.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    65. "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders. Front Aging Neurosci. 2018; 10:343. Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH. PMID: 30483114; PMCID: PMC6244607.
      View in: PubMed   Mentions: 14  
    66. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 02; 137(2):209-226. Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS. PMID: 30413934; PMCID: PMC6358498.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    67. New Antibody-Free Mass Spectrometry-Based Quantification Reveals That C9ORF72 Long Protein Isoform Is Reduced in the Frontal Cortex of Hexanucleotide-Repeat Expansion Carriers. Front Neurosci. 2018; 12:589. Viodé A, Fournier C, Camuzat A, Fenaille F, NeuroCEB Brain Bank, Latouche M, Elahi F, Le Ber I, Junot C, Lamari F, Anquetil V, Becher F. PMID: 30210275; PMCID: PMC6122177.
      View in: PubMed   Mentions: 10  
    68. ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE. Alzheimer's & Dementia. 2018 Jul 1; 14(7):p767. Elahi EF, Altendahl AM, Filshtein FT, Casaletto CK, Staffaroni SA, Contreras CW, Karydas KA, Cobigo CY, Fletcher FE, Singh SB, Martinez MO, Rosen RH, Hinman HJ, Akassoglou AK, Glymour GM, DeCarli DC, Goetzl GE, Kramer KJ. .
      View in: Publisher Site   Mentions:
    69. Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults. Am J Geriatr Psychiatry. 2018 09; 26(9):952-963. Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH. PMID: 30017239; PMCID: PMC6108924.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    70. A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence? Cytokine. 2018 11; 111:481-489. Casaletto KB, Elahi FM, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher BM, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH. PMID: 29908923; PMCID: PMC6289877.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    71. Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults. Neurobiol Aging. 2018 09; 69:68-75. Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH. PMID: 29859365; PMCID: PMC6430612.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    72. The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed. J Neurosci. 2018 03 14; 38(11):2809-2817. Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH. PMID: 29440553; PMCID: PMC5852659.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    73. Neuroimaging in Dementia. Semin Neurol. 2017 10; 37(5):510-537. Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD. PMID: 29207412; PMCID: PMC5823524.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    74. Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers. Neurology. 2017 Oct 24; 89(17):1782-1788. Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH. PMID: 28939668; PMCID: PMC5664306.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    75. Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease. Neuroimage Clin. 2017; 16:595-603. Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ. PMID: 28975068; PMCID: PMC5614750.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    76. A clinicopathological approach to the diagnosis of dementia. Nat Rev Neurol. 2017 Aug; 13(8):457-476. Elahi FM, Miller BL. PMID: 28708131; PMCID: PMC5771416.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    77. Independent and epistatic effects of Val66Met BDNF and ApoE polymorphisms on BETA-AMYLOID deposition in cognitively normal individuals using PiB-PET imaging. Alzheimer's & Dementia. 2012 Jul 1; 8(4):s757-s758. During DE, Elahi EF, Chen CK, Huentelman HM, Corneveaux CJ, Thiyyagura TP, Liu LX, Roontiva RA, Caselli CR, Fleisher FA, Lu LB, Reiman RE. .
      View in: Publisher Site   Mentions:
    78. The concept of FDG-PET endophenotype in Alzheimer's disease. Neurol Sci. 2011 Aug; 32(4):559-69. During EH, Osorio RS, Elahi FM, Mosconi L, de Leon MJ. PMID: 21630036; PMCID: PMC3831649.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    79. A critical review of dissociative trance and possession disorders: etiological, diagnostic, therapeutic, and nosological issues. Can J Psychiatry. 2011 Apr; 56(4):235-42. During EH, Elahi FM, Taieb O, Moro MR, Baubet T. PMID: 21507280.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    80. Functional genetic analysis of mutations implicated in a human speech and language disorder. Hum Mol Genet. 2006 Nov 01; 15(21):3154-67. Vernes SC, Nicod J, Elahi FM, Coventry JA, Kenny N, Coupe AM, Bird LE, Davies KE, Fisher SE. PMID: 16984964.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
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