Loading...

Fanny Elahi, MD, PhD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-6880
vCardDownload vCard
    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Overview 
    Collapse Overview
    Fanny Elahi is a board-certified neurologist with specific expertise in the evaluation and management of patients with cognitive and behavioral disorders due to degenerative brain diseases such as Alzheimer's disease and related disorders. She completed her bachelor's degree at Columbia University, her MD from Icahn School of Medicine, at Mount Sinai, and her DPhil from Oxford University. She pursued her residency in neurology at the University of California, Los Angeles and joined the University of California, San Francisco Memory and Aging Center in 2015 where she trained in neurodegenerative disorders prior to joining the faculty in the department of Neurology. Her research is focused on the identification of early biomarkers of degenerative brain disease with a particular interest in characterization of contributions of immune dysregulation and vascular disease to brain dysfunction, mood and cognitive changes, and ultimately progressive brain degeneration. Her work has been supported by the American Academy of Neurology in partnership with the Allergan foundation, the Alzheimer's Disease Research Center at the UCSF Memory and Aging Center, the National Institute of Neurological Disorders and Stroke, as well as philanthropic donations.

    Collapse Research 
    Collapse Research Activities and Funding
    Multi-cellular exosome-based biomarkers to capture the dysfunction of the neurovascular unit in early-preclinical stages of AD-related brain degeneration
    Donors Cure Foundation CCAD201903Jun 1, 2019 - May 31, 2021
    Role: Principal Investigator
    Immunomodulation to promote cerebrovascular and cognitive health
    AHA / Allen Frontiers Group Feb 1, 2019 - Jan 31, 2024
    Role: Co-Investigator
    Novel imaging and endothelial biomarkers of small vessel cerebrovascular disease
    NIH/NINDS UH3NS100608Sep 30, 2016 - Jun 30, 2021
    Role: Co-Investigator
    Effects of chronic inflammation on brain structure and function
    NIH/NIA R01AG048234Apr 15, 2015 - Jan 31, 2020
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. REM sleep is associated with white matter integrity in cognitively healthy, older adults. PLoS One. 2020; 15(7):e0235395. Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM. PMID: 32645032.
      View in: PubMed   Mentions:    Fields:    
    2. ß-amyloid and tau drive early Alzheimer's disease decline while glucose hypometabolism drives late decline. Commun Biol. 2020 Jul 06; 3(1):352. Hammond TC, Xing X, Wang C, Ma D, Nho K, Crane PK, Elahi F, Ziegler DA, Liang G, Cheng Q, Yanckello LM, Jacobs N, Lin AL. PMID: 32632135.
      View in: PubMed   Mentions:
    3. Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates. Am J Geriatr Psychiatry. 2020 May 15. Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB. PMID: 32527600.
      View in: PubMed   Mentions:    Fields:    
    4. Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. Brain Behav Immun. 2020 May 06. Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH. PMID: 32387511.
      View in: PubMed   Mentions:    Fields:    
    5. Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy. FASEB J. 2020 Apr; 34(4):5967-5974. Abner EL, Elahi FM, Jicha GA, Mustapic M, Al-Janabi O, Kramer JH, Kapogiannis D, Goetzl EJ. PMID: 32157747.
      View in: PubMed   Mentions:    Fields:    
    6. The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases. Expert Rev Mol Diagn. 2020 Apr; 20(4):421-441. Baldacci F, Mazzucchi S, Della Vecchia A, Giampietri L, Giannini N, Koronyo-Hamaoui M, Ceravolo R, Siciliano G, Bonuccelli U, Elahi FM, Vergallo A, Lista S, Giorgi FS, Hampel H. PMID: 32066283.
      View in: PubMed   Mentions:    Fields:    
    7. An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury. PLoS One. 2020; 15(1):e0227835. Altendahl M, Maillard P, Harvey D, Cotter D, Walters S, Wolf A, Singh B, Kakarla V, Azizkhanian I, Sheth SA, Xiao G, Fox E, You M, Leng M, Elashoff D, Kramer JH, Decarli C, Elahi F, Hinman JD. PMID: 31978079.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease. Alzheimers Dement. 2020 04; 16(4):681-695. Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH. PMID: 31879236.
      View in: PubMed   Mentions:    Fields:    
    9. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. 2020 01; 577(7790):399-404. Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. PMID: 31915375.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimers Dement. 2020 01; 16(1):11-21. Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ. PMID: 31914230.
      View in: PubMed   Mentions:    Fields:    
    11. Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration. Alzheimers Dement. 2020 01; 16(1):91-105. Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K. PMID: 31914227.
      View in: PubMed   Mentions:    Fields:    
    12. Acute Insulin Resistance and Rapid Alterations in Neuronal Derived Blood Exosome Concentration After Branched Endovascular Aortic Aneurysm Repair. Eur J Vasc Endovasc Surg. 2020 Mar; 59(3):457-463. Hiramoto JS, Elahi FM, Gasper WJ, Reilly LM, Chuter TA, Goetzl EJ. PMID: 31866237.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. Stem Cells. 2020 01; 38(1):15-21. Elahi FM, Farwell DG, Nolta JA, Anderson JD. PMID: 31381842.
      View in: PubMed   Mentions: 8     Fields:    
    14. Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. J Gerontol A Biol Sci Med Sci. 2019 Sep 24. Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH. PMID: 31549145.
      View in: PubMed   Mentions:    Fields:    
    15. Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality. Alzheimers Dement. 2019 07; 15(7):907-916. Filshtein TJ, Brenowitz WD, Mayeda ER, Hohman TJ, Walter S, Jones RN, Elahi FM, Glymour MM. PMID: 31327391.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p846-p847. Sophia A. Weiner-Light, Samantha Walters, Nina Djukic, Michelle You, Devyn Cotter, Marie Altendahl, Fanny Elahi, Adam M. Staffaroni, Cutter A. Lindbergh, Joel H. Kramer, Kaitlin B. Casaletto. .
      View in: Publisher Site   Mentions:
    17. Neuron-Derived Exosome Proteins May Contribute to Progression From Repetitive Mild Traumatic Brain Injuries to Chronic Traumatic Encephalopathy. Front Neurosci. 2019; 13:452. Goetzl EJ, Ledreux A, Granholm AC, Elahi FM, Goetzl L, Hiramoto J, Kapogiannis D. PMID: 31133789.
      View in: PubMed   Mentions:
    18. A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure. Hum Brain Mapp. 2019 08 15; 40(12):3522-3533. Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH. PMID: 31062904.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time. Front Aging Neurosci. 2019; 11:25. Bettcher BM, Neuhaus J, Wynn MJ, Elahi FM, Casaletto KB, Saloner R, Fitch R, Karydas A, Kramer JH. PMID: 30814948.
      View in: PubMed   Mentions:
    20. Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials. Brain. 2019 02 01; 142(2):443-459. Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ. PMID: 30698757.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    21. Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults. Neurobiol Aging. 2019 05; 77:13-19. Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH. PMID: 30772736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia. Alzheimers Dement (Amst). 2019 Dec; 11:61-66. Winston CN, Goetzl EJ, Schwartz JB, Elahi FM, Rissman RA. PMID: 31032394.
      View in: PubMed   Mentions:
    23. Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury. FASEB J. 2019 04; 33(4):5082-5088. Goetzl EJ, Elahi FM, Mustapic M, Kapogiannis D, Pryhoda M, Gilmore A, Gorgens KA, Davidson B, Granholm AC, Ledreux A. PMID: 30605353.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 02; 137(2):209-226. Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS. PMID: 30413934.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders. Front Aging Neurosci. 2018; 10:343. Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH. PMID: 30483114.
      View in: PubMed   Mentions:
    26. New Antibody-Free Mass Spectrometry-Based Quantification Reveals That C9ORF72 Long Protein Isoform Is Reduced in the Frontal Cortex of Hexanucleotide-Repeat Expansion Carriers. Front Neurosci. 2018; 12:589. Viodé A, Fournier C, Camuzat A, Fenaille F, Latouche M, Elahi F, Le Ber I, Junot C, Lamari F, Anquetil V, Becher F. PMID: 30210275.
      View in: PubMed   Mentions:
    27. ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE. Alzheimer's & Dementia. 2018 Jul 1; 14(7):p767. Fanny Elahi, Marie Altendahl, Teresa J. Filshtein, Kaitlin Casaletto, Adam M. Staffaroni, Wilfredo Rivera Contreras, Anna M. Karydas, Yann Cobigo, Evan Fletcher, Baljeet Singh, Oliver Martinez, Howard J. Rosen, Jason Hinman, Katerina Akassoglou, Maria Glymour, Charlie S. DeCarli, Edward J. Goetzl, Joel H. Kramer. .
      View in: Publisher Site   Mentions:
    28. Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults. Am J Geriatr Psychiatry. 2018 09; 26(9):952-963. Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH. PMID: 30017239.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    29. A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence? Cytokine. 2018 11; 111:481-489. Casaletto KB, Elahi FM, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher BM, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH. PMID: 29908923.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults. Neurobiol Aging. 2018 09; 69:68-75. Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH. PMID: 29859365.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed. J Neurosci. 2018 03 14; 38(11):2809-2817. Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH. PMID: 29440553.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    32. Neuroimaging in Dementia. Semin Neurol. 2017 10; 37(5):510-537. Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD. PMID: 29207412.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers. Neurology. 2017 Oct 24; 89(17):1782-1788. Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH. PMID: 28939668.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease. Neuroimage Clin. 2017; 16:595-603. Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ. PMID: 28975068.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    35. A clinicopathological approach to the diagnosis of dementia. Nat Rev Neurol. 2017 Aug; 13(8):457-476. Elahi FM, Miller BL. PMID: 28708131.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. Independent and epistatic effects of Val66Met BDNF and ApoE polymorphisms on BETA-AMYLOID deposition in cognitively normal individuals using PiB-PET imaging. Alzheimer's & Dementia. 2012 Jul 1; 8(4):s757-s758. Emmanuel During, Fanny Elahi, Kewei Chen, Matthew Huentelman, Jason Corneveaux, Pradeep Thiyyagura, Xiaofen Liu, Auttawut Roontiva, Richard Caselli, Adam Fleisher, Bai Lu, Eric Reiman. .
      View in: Publisher Site   Mentions:
    37. The concept of FDG-PET endophenotype in Alzheimer's disease. Neurol Sci. 2011 Aug; 32(4):559-69. During EH, Osorio RS, Elahi FM, Mosconi L, de Leon MJ. PMID: 21630036.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. A critical review of dissociative trance and possession disorders: etiological, diagnostic, therapeutic, and nosological issues. Can J Psychiatry. 2011 Apr; 56(4):235-42. During EH, Elahi FM, Taieb O, Moro MR, Baubet T. PMID: 21507280.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Functional genetic analysis of mutations implicated in a human speech and language disorder. Hum Mol Genet. 2006 Nov 01; 15(21):3154-67. Vernes SC, Nicod J, Elahi FM, Coventry JA, Kenny N, Coupe AM, Bird LE, Davies KE, Fisher SE. PMID: 16984964.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    Fanny's Networks
    Concepts (141)
    Derived automatically from this person's publications.
    _
    Co-Authors (64)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _