Feroz Papa, MD, PhD
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Title(s) | Professor, Medicine |
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School | School of Medicine |
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Address | 1700 4th St San Francisco CA 94158
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Phone | 415-476-2117 |
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vCard | Download vCard |
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Biography University of California, San Francisco | Postdoctoral Studies | | Graduate Division |
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
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Targeting Adaptive IRE1a Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib. Int J Mol Sci. 2020 Aug 31; 21(17).
Yamashita Y, Morita S, Hosoi H, Kobata H, Kishimoto S, Ishibashi T, Mishima H, Kinoshita A, Backes BJ, Yoshiura KI, Papa FR, Sonoki T, Tamura S. PMID: 32878237.
View in: PubMed Mentions: Fields:
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Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1a activation to protect ß-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress. J Diabetes Investig. 2020 Jul; 11(4):801-813.
Ishibashi T, Morita S, Kishimoto S, Uraki S, Takeshima K, Furukawa Y, Inaba H, Ariyasu H, Iwakura H, Furuta H, Nishi M, Papa FR, Akamizu T. PMID: 31925927.
View in: PubMed Mentions: 2 Fields:
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Parallel Signaling through IRE1a and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival. Cancer Res. 2019 12 15; 79(24):6190-6203.
Moore PC, Qi JY, Thamsen M, Ghosh R, Peng J, Gliedt MJ, Meza-Acevedo R, Warren RE, Hiniker A, Kim GE, Maly DJ, Backes BJ, Papa FR, Oakes SA. PMID: 31672843.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1. ACS Chem Biol. 2019 12 20; 14(12):2595-2605.
Feldman HC, Vidadala VN, Potter ZE, Papa FR, Backes BJ, Maly DJ. PMID: 31609569.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Endoplasmic reticulum stress, degeneration of pancreatic islet ß-cells, and therapeutic modulation of the unfolded protein response in diabetes. Mol Metab. 2019 09; 27S:S60-S68.
Ghosh R, Colon-Negron K, Papa FR. PMID: 31500832.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Small Molecules to Improve ER Proteostasis in Disease. Trends Pharmacol Sci. 2019 09; 40(9):684-695.
Gonzalez-Teuber V, Albert-Gasco H, Auyeung VC, Papa FR, Mallucci GR, Hetz C. PMID: 31377018.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11291-11298.
Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. PMID: 31101715.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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Small molecule inhibition of IRE1a kinase/RNase has anti-fibrotic effects in the lung. PLoS One. 2019; 14(1):e0209824.
Thamsen M, Ghosh R, Auyeung VC, Brumwell A, Chapman HA, Backes BJ, Perara G, Maly DJ, Sheppard D, Papa FR. PMID: 30625178.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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Pancreatic Neuroendocrine Tumors Require Homeostatic Signaling from the Unfolded Protein Response. The FASEB Journal. 2018 Apr 1; 32:407.12-407.12.
Scott A. Oakes, Paul C. Moore, Jenny Y. Qi, Rachel Warren, Maike Thamsen, Rajarshi Ghosh, Micah J. Gliedt, Anne Hiniker, Grace E. Kim, Dustin J. Maly, Bradley J. Backes, Feroz R. Papa. .
View in: Publisher Site Mentions:
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The Unfolded Protein Response and Cell Fate Control. Mol Cell. 2018 01 18; 69(2):169-181.
Hetz C, Papa FR. PMID: 29107536.
View in: PubMed Mentions: 176 Fields: Translation: HumansAnimalsCells
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Targeting ABL-IRE1a Signaling Spares ER-Stressed Pancreatic ß Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 05 02; 25(5):1207.
PMID: 28467938.
View in: PubMed Mentions: 7 Fields:
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Targeting ABL-IRE1a Signaling Spares ER-Stressed Pancreatic ß Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 Apr 04; 25(4):883-897.e8.
PMID: 28380378.
View in: PubMed Mentions: 32 Fields: Translation: HumansAnimalsCells
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All trans retinoic acid depresses the content and activity of the mitochondrial ATP synthase in human keratinocytes. Biochem Biophys Res Commun. 2017 Jan 08; 482(2):301-304.
PMID: 27856255.
View in: PubMed Mentions: 1 Fields: Translation: HumansCells
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Structural and Functional Analysis of the Allosteric Inhibition of IRE1a with ATP-Competitive Ligands. ACS Chem Biol. 2016 08 19; 11(8):2195-205.
PMID: 27227314.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
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Correction: X-Box Binding Protein 1 (XBP1s) Is a Critical Determinant of Pseudomonas aeruginosa Homoserine Lactone-Mediated Apoptosis. PLoS Pathog. 2016 May; 12(5):e1005628.
PMID: 27191388.
View in: PubMed Mentions: Fields:
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COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015 Jun; 47(6):654-60.
PMID: 25894502.
View in: PubMed Mentions: 61 Fields: Translation: HumansCells
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Druggable sensors of the unfolded protein response. Nat Chem Biol. 2014 Nov; 10(11):892-901.
PMID: 25325700.
View in: PubMed Mentions: 54 Fields: Translation: HumansAnimalsCells
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The role of endoplasmic reticulum stress in human pathology. Annu Rev Pathol. 2015; 10:173-94.
PMID: 25387057.
View in: PubMed Mentions: 159 Fields: Translation: HumansAnimalsCells
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Allosteric inhibition of the IRE1a RNase preserves cell viability and function during endoplasmic reticulum stress. Cell. 2014 Jul 31; 158(3):534-48.
PMID: 25018104.
View in: PubMed Mentions: 133 Fields: Translation: HumansAnimalsCells
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Feroz Papa: Saving cells from themselves. J Cell Biol. 2014 Mar 03; 204(5):628-9.
PMID: 24590168.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Establishment of a system for monitoring endoplasmic reticulum redox state in mammalian cells. Lab Invest. 2013 Nov; 93(11):1254-8.
PMID: 24042438.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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X-box binding protein 1 (XBP1s) is a critical determinant of Pseudomonas aeruginosa homoserine lactone-mediated apoptosis. PLoS Pathog. 2013; 9(8):e1003576.
PMID: 23990788.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCells
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Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis. Respir Res. 2012 Nov 20; 13:105.
PMID: 23167970.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
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Divergent allosteric control of the IRE1a endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec; 8(12):982-9.
PMID: 23086298.
View in: PubMed Mentions: 69 Fields: Translation: HumansCells
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IRE1a cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science. 2012 Nov 09; 338(6108):818-22.
PMID: 23042294.
View in: PubMed Mentions: 207 Fields: Translation: HumansAnimalsCells
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Endoplasmic reticulum stress, pancreatic ß-cell degeneration, and diabetes. Cold Spring Harb Perspect Med. 2012 Sep 01; 2(9):a007666.
PMID: 22951443.
View in: PubMed Mentions: 66 Fields: Translation: HumansCells
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IRE1a induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab. 2012 Aug 08; 16(2):250-64.
PMID: 22883233.
View in: PubMed Mentions: 243 Fields: Translation: HumansAnimalsCells
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IRE1-dependent activation of AMPK in response to nitric oxide. Mol Cell Biol. 2011 Nov; 31(21):4286-97.
Meares GP, Hughes KJ, Naatz A, Papa FR, Urano F, Hansen PA, Benveniste EN, Corbett JA. PMID: 21896783.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
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Signaling cell death from the endoplasmic reticulum stress response. Curr Opin Cell Biol. 2011 Apr; 23(2):143-9.
PMID: 21146390.
View in: PubMed Mentions: 112 Fields: Translation: HumansAnimalsCells
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The UPR and cell fate at a glance. J Cell Sci. 2010 Apr 01; 123(Pt 7):1003-6.
Merksamer PI, Papa FR. PMID: 20332117.
View in: PubMed Mentions: 46 Fields: Translation: HumansAnimalsCells
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Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1. J Biol Chem. 2010 Feb 26; 285(9):6693-705.
Lei X, Zhang S, Barbour SE, Bohrer A, Ford EL, Koizumi A, Papa FR, Ramanadham S. PMID: 20032468.
View in: PubMed Mentions: 34 Fields: Translation: HumansAnimalsCells
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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell. 2009 Aug 07; 138(3):562-75.
Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR. PMID: 19665977.
View in: PubMed Mentions: 325 Fields: Translation: AnimalsCells
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IRE1a Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates. Journal of End-to-End-testing. 2009 Aug 7; 138(33):562-575.
Dan Han, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, Feroz R. Papa. .
View in: Publisher Site Mentions:
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IRE1a Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates. Journal of End-to-End-testing. 2009 Aug 7; 138(3):562-575.
Dan Han, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, Feroz R. Papa. .
View in: Publisher Site Mentions:
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Rationalizing translation attenuation in the network architecture of the unfolded protein response. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20280-5.
Trusina A, Papa FR, Tang C. PMID: 19075238.
View in: PubMed Mentions: 20 Fields: Translation: AnimalsCells
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Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. Cell. 2008 Nov 28; 135(5):933-47.
Merksamer PI, Trusina A, Papa FR. PMID: 19026441.
View in: PubMed Mentions: 113 Fields: Translation: AnimalsCells
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Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress. Mol Cell Biol. 2008 Jun; 28(12):3943-51.
Upton JP, Austgen K, Nishino M, Coakley KM, Hagen A, Han D, Papa FR, Oakes SA. PMID: 18426910.
View in: PubMed Mentions: 78 Fields: Translation: AnimalsCells
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Translation Attenuation Mechanism in Unfolded Protein Response. Evolution from Cellular to Social Scales. 2008 Jan 1; 83-90.
Ala Trusina, Feroz Papa, Chao Tang. .
View in: Publisher Site Mentions:
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A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress. Biochem Biophys Res Commun. 2008 Jan 25; 365(4):777-83.
Han D, Upton JP, Hagen A, Callahan J, Oakes SA, Papa FR. PMID: 18035051.
View in: PubMed Mentions: 25 Fields: Translation: AnimalsCells
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Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol. 2006; 22:487-508.
Bernales S, Papa FR, Walter P. PMID: 16822172.
View in: PubMed Mentions: 240 Fields: Translation: AnimalsCells
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On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18773-84.
Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P. PMID: 16365312.
View in: PubMed Mentions: 194 Fields: Translation: HumansAnimalsCells
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Bypassing a kinase activity with an ATP-competitive drug. Science. 2003 Nov 28; 302(5650):1533-7.
Papa FR, Zhang C, Shokat K, Walter P. PMID: 14564015.
View in: PubMed Mentions: 100 Fields: Translation: Cells
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Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome. Mol Biol Cell. 1999 Mar; 10(3):741-56.
Papa FR, Amerik AY, Hochstrasser M. PMID: 10069815.
View in: PubMed Mentions: 40 Fields: Translation: AnimalsCells
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An evolutionarily conserved gene on human chromosome 5q33-q34, UBH1, encodes a novel deubiquitinating enzyme. Genomics. 1998 May 01; 49(3):411-8.
Hansen-Hagge TE, Janssen JW, Hameister H, Papa FR, Zechner U, Seriu T, Jauch A, Becke D, Hochstrasser M, Bartram CR. PMID: 9615226.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
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DUB-1, a deubiquitinating enzyme with growth-suppressing activity. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3275-9.
Zhu Y, Carroll M, Papa FR, Hochstrasser M, D'Andrea AD. PMID: 8622927.
View in: PubMed Mentions: 35 Fields: Translation: AnimalsCells
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The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Mol Cell Biol. 1995 Nov; 15(11):6311-21.
DeMarini DJ, Papa FR, Swaminathan S, Ursic D, Rasmussen TP, Culbertson MR, Hochstrasser M. PMID: 7565784.
View in: PubMed Mentions: 31 Fields: Translation: AnimalsCells
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The DOA pathway: studies on the functions and mechanisms of ubiquitin-dependent protein degradation in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol. 1995; 60:503-13.
Hochstrasser M, Papa FR, Chen P, Swaminathan S, Johnson P, Stillman L, Amerik AY, Li SJ. PMID: 8824423.
View in: PubMed Mentions: 8 Fields: Translation: HumansAnimalsCells
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The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature. 1993 Nov 25; 366(6453):313-9.
Papa FR, Hochstrasser M. PMID: 8247125.
View in: PubMed Mentions: 110 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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1993 | 1 | 1995 | 2 | 1996 | 1 | 1998 | 1 | 1999 | 1 | 2003 | 1 | 2005 | 1 | 2006 | 1 | 2007 | 1 | 2008 | 4 | 2009 | 4 | 2010 | 2 | 2011 | 1 | 2012 | 5 | 2013 | 2 | 2014 | 4 | 2015 | 1 | 2016 | 3 | 2017 | 3 | 2018 | 1 | 2019 | 6 | 2020 | 2 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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