Frederick Hecht, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1545 Divisadero Street
San Francisco CA 94115
Phone415-475-4082
ORCID ORCID Icon0000-0002-5782-1171 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, San FranciscoPost-doctoral fellowship1993Clinical epidemiology -general internal medicine
    Einstein-Montifiore Residency Program in Social Medicine, Bronx, NY1989Internal Medicine residency
    SUNY Brooklyn, Brooklyn, NYMD1986Medicine
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    I am trained in Internal Medicine, with additional training in clinical research methods, biostatistics, and behavioral medicine. My research focus for many years was on HIV. I developed one of the largest cohorts in the world of persons followed from primary HIV (within 6 months of infection), the Options Project, in which we have examined clinical, behavioral, cardiovascular, and immunologic research questions. In 2002, I became Director of Research at the UCSF Osher Center for Integrative Medicine. My research is driven by the belief that modern medicine has made impressive advances in treating a range of health conditions, but that further advances for many of the most important health problems of our era, including obesity, diabetes, heart disease, and mental health issues require improved development and implementation of lifestyle and other non-pharmacologic approaches. An important goal of my research program is to rigorously test whether we can improve interventions for chronic health problems such as HIV, diabetes, obesity, and stress, by incorporating mindfulness and/or yoga-based components. A current example is an NIH-funded study to test whether including training in mindful eating practices decreases eating in response to food cravings and enhances adherence to a nutritional plan in type 2 diabetes.

    In my role as Director of the UCSF Osher Center Research Program, I have played a key leadership role in building it into an internationally recognized integrative medicine research center that is distinguished by the application of innovative and rigorous research designs to studying mindfulness-based interventions, yoga, acupuncture, interoceptive awareness, and behavioral interventions. I served in a variety of leadership roles in HIV medicine and integrative medicine, including as chair of the Organizing Committee of the 2016 International Congress on Integrative Medicine and Health, which gives me a broad view of the field. I have a strong commitment to mentoring. I have led UCSF’s highly successful Training Research in Integrative Medicine (TRIM) fellowship program since 2006, and have served as a primary or main co-mentor on 11 K awards. I have served as PI or co-PI/project director for 29 grants, 17 of them from NIH, including leading three Program Project grants.

    Collapse Research 
    Collapse Research Activities and Funding
    Feasibility Clinical Trial of Integrated Mind-Body Therapy for Chronic Low Back Pain
    NIH R34AT010921Dec 15, 2020 - Nov 30, 2023
    Role: Co-Principal Investigator
    2020 International Congress for Integrative Medicine and Health
    NIH R13AT010842Dec 15, 2019 - Dec 14, 2020
    Role: Principal Investigator
    Optimizing lifestyle interventions with mindfulness-based strategies in type 2 diabetes
    NIH R33AT009333Sep 15, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Optimizing lifestyle interventions with mindfulness-based strategies in type 2 diabetes
    NIH R61AT009333Sep 15, 2016 - Sep 14, 2018
    Role: Principal Investigator
    Predictors of Outcomes in MBSR Participants from Teacher Factors
    NIH R34AT008948Aug 1, 2016 - Jul 31, 2020
    Role: Principal Investigator
    2016 International Congress on Integrative Medicine and Health
    NIH R13AT009166Mar 1, 2016 - Feb 28, 2017
    Role: Principal Investigator
    Mentoring and Research in Integrative Medicine
    NIH K24AT007827Mar 1, 2013 - Feb 28, 2023
    Role: Principal Investigator
    DARE: Delaney AIDS Research Enterprise to find a cure.
    NIH U19AI096109Jul 8, 2011 - Jun 30, 2017
    Role: Co-Investigator
    Metabolic and Immunologic Effects of Meditation
    NIH P01AT005013Sep 30, 2008 - May 31, 2015
    Role: Principal Investigator
    The Biology of HIV Transmission
    NIH P01AI071713Sep 1, 2007 - Aug 31, 2014
    Role: Principal Investigator
    Training Researchers in Clinical Integrative Medicine (TRIM)
    NIH T32AT003997Jul 1, 2007 - Aug 31, 2022
    Role: Principal Investigator
    Human Natural Killer Cell Biology
    NIH P01AI064520Sep 16, 2005 - Feb 28, 2011
    Role: Co-Investigator
    MBSR, Stress Arousal and Immune Response in Early HIV
    NIH P01AT002024Sep 30, 2004 - Jun 30, 2010
    Role: Principal Investigator
    Yoga, Health, and Meditation
    NIH R21AT001942Sep 22, 2003 - Mar 31, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Featured Content 
    Collapse Featured Videos
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Exploratory Analysis of Racial/Ethnic and Educational Differences in a Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention. Psychosom Med. 2021 Jul-Aug 01; 83(6):503-514. Daubenmier J, Chao MT, Hartogensis W, Liu R, Moran PJ, Acree MC, Kristeller J, Epel ES, Hecht FM. PMID: 33214537.
      View in: PubMed   Mentions:    Fields:    
    2. Frequency of Post Treatment Control Varies by ART Restart and Viral Load Criteria. AIDS. 2021 Jun 14. Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ, CHAMP study team . PMID: 34127579.
      View in: PubMed   Mentions: 1     Fields:    
    3. Cellular activation, differentiation and proliferation influence the dynamics of genetically-intact proviruses over time. J Infect Dis. 2021 May 26. Horsburgh BA, Hiener B, Fisher K, Lee E, Morgan H, Eden JS, von Stockenstrom S, Odevall L, Milush JM, Hoh R, Fromentin R, Chomont N, Hecht FM, Schlub TE, Deeks SG, Palmer S. PMID: 34037766.
      View in: PubMed   Mentions:    Fields:    
    4. Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus. J Infect Dis. 2021 May 20; 223(9):1621-1630. Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW. PMID: 32915986.
      View in: PubMed   Mentions: 2     Fields:    
    5. Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials. Ann Surg. 2021 03 01; 273(3):424-432. Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW. PMID: 32773637.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. JCI Insight. 2021 02 08; 6(3). Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. PMID: 33351785.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART. PLoS Pathog. 2021 01; 17(1):e1009214. Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. PMID: 33465157.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Corrigendum: Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience. Front Psychol. 2020; 11:631816. Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM. PMID: 33488490.
      View in: PubMed   Mentions:
    9. Feasibility of continuous fever monitoring using wearable devices. Sci Rep. 2020 12 14; 10(1):21640. Smarr BL, Aschbacher K, Fisher SM, Chowdhary A, Dilchert S, Puldon K, Rao A, Hecht FM, Mason AE. PMID: 33318528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial. Glob Adv Health Med. 2020; 9:2164956120964712. Dhruva A, Wu C, Miaskowski C, Hartogensis W, Rugo HS, Adler SR, Kaptchuk TJ, Kelkar R, Agarawal S, Vadodaria A, Garris E, Hecht FM. PMID: 33312762.
      View in: PubMed   Mentions:
    11. Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience. Front Psychol. 2020; 11:573134. Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM. PMID: 33329215.
      View in: PubMed   Mentions:
    12. Can We Agree What Skilled Mindfulness-Based Teaching Looks Like? Lessons From Studying the MBI:TAC. Glob Adv Health Med. 2020; 9:2164956120964733. S Crane R, Hecht FM, Brewer J, Griffith GM, Hartogensis W, Koerbel L, Moran P, Sansom S, Yiangou A, Kuyken W. PMID: 33110709.
      View in: PubMed   Mentions:
    13. Pilot Cluster Randomized Controlled Trial of Integrative Nutritional Counseling Versus Standard Diabetes Self-Management Education for Chinese Americans with Type 2 Diabetes. Health Equity. 2020; 4(1):410-420. Ho EY, Pak S, Leung G, Xu S, Yu CK, Hecht FM, Jih J, Chao MT. PMID: 33111026.
      View in: PubMed   Mentions:
    14. Intervention Enhancement Strategies Among Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Evaluating the Impact With a Randomized Trial. JMIR Diabetes. 2020 Sep 09; 5(3):e15835. Saslow LR, Moskowitz JT, Mason AE, Daubenmier J, Liestenfeltz B, Missel AL, Bayandorian H, Aikens JE, Kim S, Hecht FM. PMID: 32902391.
      View in: PubMed   Mentions:
    15. Focus on the Breath: Brain Decoding Reveals Internal States of Attention During Meditation. Front Hum Neurosci. 2020; 14:336. Weng HY, Lewis-Peacock JA, Hecht FM, Uncapher MR, Ziegler DA, Farb NAS, Goldman V, Skinner S, Duncan LG, Chao MT, Gazzaley A. PMID: 33005138.
      View in: PubMed   Mentions:
    16. Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection. J Virol. 2020 07 01; 94(14). Scharf L, Tauriainen J, Buggert M, Hartogensis W, Nolan DJ, Deeks SG, Salemi M, Hecht FM, Karlsson AC. PMID: 32350076.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    17. Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy. J Clin Invest. 2020 07 01; 130(7):3543-3559. Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF. PMID: 32191639.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    18. "It Gave Me Hope" Experiences of Diverse Safety Net Patients in a Group Acupuncture Intervention for Painful Diabetic Neuropathy. Health Equity. 2020; 4(1):225-231. Liu R, Santana T, Schillinger D, Hecht FM, Chao MT. PMID: 32462104.
      View in: PubMed   Mentions:
    19. Semen virome of men with HIV on or off antiretroviral treatment. AIDS. 2020 05 01; 34(6):827-832. Li Y, Altan E, Pilcher C, Hartogensis W, Hecht FM, Deng X, Delwart E. PMID: 32271249.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies. AIDS. 2020 04 01; 34(5):659-668. Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31913161.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Human Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy. J Infect Dis. 2020 02 18; 221(5):744-755. Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU, Deeks SG, Lewin SR. PMID: 31796951.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites. J Virol. 2020 01 17; 94(3). Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31723024.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    23. Correction: Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2020 Jan 13; 9(1):e17226. Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F. PMID: 31929107.
      View in: PubMed   Mentions:
    24. Correction to: Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study. Nutr Metab (Lond). 2019; 16:91. Mason AE, Saslow LR, Moran PJ, Kim S, Wali PK, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM. PMID: 31892933.
      View in: PubMed   Mentions:
    25. Ketogenic Diets for Diabetes and Obesity. JAMA Intern Med. 2019 12 01; 179(12):1734. Hecht FM. PMID: 31790525.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Do stress eating or compulsive eating influence metabolic health in a mindfulness-based weight loss intervention? Health Psychol. 2020 Feb; 39(2):147-158. Radin RM, Epel ES, Daubenmier J, Moran P, Schleicher S, Kristeller J, Hecht FM, Mason AE. PMID: 31724424.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. A Randomized Clinical Trial of Group Acupuncture for Painful Diabetic Neuropathy Among Diverse Safety Net Patients. Pain Med. 2019 11 01; 20(11):2292-2302. Chao MT, Schillinger D, Nguyen U, Santana T, Liu R, Gregorich S, Hecht FM. PMID: 31127837.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Effects of a Mindfulness-Based Intervention on Distress, Weight Gain, and Glucose Control for Pregnant Low-Income Women: A Quasi-Experimental Trial Using the ORBIT Model. Int J Behav Med. 2019 Oct; 26(5):461-473. Epel E, Laraia B, Coleman-Phox K, Leung C, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland N, Bush N, Lustig RH, Dallman M, Hecht FM, Adler N. PMID: 30993601.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Acupressure and Therapeutic Touch in Childhood Cancer to Promote Subjective and Intersubjective Experiences of Well-being During Curative Treatment. Glob Adv Health Med. 2019; 8:2164956119880143. Hu H, Shear D, Thakkar R, Thompson-Lastad A, Pinderhughes H, Hecht FM, Lown EA. PMID: 31632842.
      View in: PubMed   Mentions:
    30. Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy. Front Microbiol. 2019; 10:2214. Lee E, Bacchetti P, Milush J, Shao W, Boritz E, Douek D, Fromentin R, Liegler T, Hoh R, Deeks SG, Hecht FM, Chomont N, Palmer S. PMID: 31611857.
      View in: PubMed   Mentions:
    31. A Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention on Cardiovascular Reactivity to Social-Evaluative Threat Among Adults with Obesity. Mindfulness (N Y). 2019 Dec; 10(12):2583-2595. Daubenmier J, Epel ES, Moran PJ, Thompson J, Mason AE, Acree M, Goldman V, Kristeller J, Hecht FM, Mendes WB. PMID: 32266044.
      View in: PubMed   Mentions:
    32. Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study. Nutr Metab (Lond). 2019; 16:58. Mason AE, Saslow LR, Moran PJ, Kim S, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM. PMID: 31467583.
      View in: PubMed   Mentions:
    33. Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial. Glob Adv Health Med. 2019; 8:2164956119870444. Lown EA, Banerjee A, Vittinghoff E, Dvorak CC, Hartogensis W, Melton A, Mangurian C, Hu H, Shear D, Adcock R, Morgan M, Golden C, Hecht FM. PMID: 31453017.
      View in: PubMed   Mentions:
    34. Academic Consortium for Integrative Medicine & Health Commentary to CMS; RE: National Coverage Analysis (NCA) Tracking Sheet for Acupuncture for Chronic Low Back Pain (CAG-00452N). Glob Adv Health Med. 2019; 8:2164956119857648. Nielsen A, Tick H, Mao JJ, Hecht F, Consortium Pain Task Force . PMID: 31321149.
      View in: PubMed   Mentions:
    35. Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2019 02 20; 8(2):e11002. Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F. PMID: 30545813.
      View in: PubMed   Mentions:
    36. PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. Nat Commun. 2019 02 18; 10(1):814. Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. PMID: 30778080.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    37. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    38. Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1. AIDS. 2018 09 24; 32(15):2119-2128. Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N, Perelson AS, Lewin SR. PMID: 30005017.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    39. Burnout and gender in surgical training: A call to re-evaluate coping and dysfunction. Am J Surg. 2018 10; 216(4):800-804. Lebares CC, Braun HJ, Guvva EV, Epel ES, Hecht FM. PMID: 30197022.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Weight Loss Maintenance and Cellular Aging in the Supporting Health Through Nutrition and Exercise Study. Psychosom Med. 2018 09; 80(7):609-619. Mason AE, Hecht FM, Daubenmier JJ, Sbarra DA, Lin J, Moran PJ, Schleicher SG, Acree M, Prather AA, Epel ES. PMID: 29901486.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. A randomized, controlled trial of mindfulness-based stress reduction in HIV infection. Brain Behav Immun. 2018 10; 73:331-339. Hecht FM, Moskowitz JT, Moran P, Epel ES, Bacchetti P, Acree M, Kemeny ME, Mendes WB, Duncan LG, Weng H, Levy JA, Deeks SG, Folkman S. PMID: 29842903.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    42. Increasing Physical Activity in Mothers Using Video Exercise Groups and Exercise Mobile Apps: Randomized Controlled Trial. J Med Internet Res. 2018 05 18; 20(5):e179. Mascarenhas MN, Chan JM, Vittinghoff E, Van Blarigan EL, Hecht F. PMID: 29776899.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Novel Interventions to Reduce Stress and Overeating in Overweight Pregnant Women: A Feasibility Study. Matern Child Health J. 2018 05; 22(5):670-678. Laraia BA, Adler NE, Coleman-Phox K, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland NE, Lustig RH, Dallman MF, Hecht FM, Bush NR, de Groat CL, Epel E. PMID: 29455384.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Authors' Reply: Comment on "An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial". J Med Internet Res. 2018 05 01; 20(5):e181. Saslow L, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, Bayandorian H, Daubenmier J, Hecht FM, Moskowitz JT. PMID: 29716886.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Positive and Negative Self-Conscious Emotion and Transmission Risk Following HIV Diagnosis. AIDS Behav. 2018 05; 22(5):1496-1502. Batchelder AW, Carrico AW, Acree M, Hecht FM, Moskowitz JT. PMID: 29086116.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    46. Intervention Integrity in Mindfulness-Based Research. Mindfulness (N Y). 2018; 9(5):1370-1380. Crane RS, Hecht FM. PMID: 30294386.
      View in: PubMed   Mentions:
    47. Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. J Immunol. 2018 03 01; 200(5):1876-1888. Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 29352005.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    48. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Nutr Diabetes. 2017 12 21; 7(12):304. Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, Ploutz-Snyder R, Goldman V, Cox RM, Mason AE, Moran P, Hecht FM. PMID: 29269731.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    49. Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants. Cell Rep. 2017 Oct 17; 21(3):813-822. Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 29045846.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansCells
    50. Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. Retrovirology. 2017 Aug 22; 14(1):41. de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. PMID: 28830571.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    51. Enriched environment and stress exposure influence splenic B lymphocyte composition. PLoS One. 2017; 12(7):e0180771. Gurfein BT, Hasdemir B, Milush JM, Touma C, Palme R, Nixon DF, Darcel N, Hecht FM, Bhargava A. PMID: 28704473.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81. Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. PMID: 28498985.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    53. Improving Assessment of the Spectrum of Reward-Related Eating: The RED-13. Front Psychol. 2017; 8:795. Mason AE, Vainik U, Acree M, Tomiyama AJ, Dagher A, Epel ES, Hecht FM. PMID: 28611698.
      View in: PubMed   Mentions:
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    171. Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus. PLoS Pathog. 2008 Oct; 4(10):e1000185. Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, Liegler TJ, Hecht FM, Grant RM, Nixon DF. PMID: 18949024.
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    172. Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy. Brain Behav Immun. 2008 Nov; 22(8):1257-62. Carrico AW, Johnson MO, Morin SF, Remien RH, Riley ED, Hecht FM, Fuchs D. PMID: 18703133.
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    173. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. AIDS. 2008 Apr 23; 22(7):835-9. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. PMID: 18427201.
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    174. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nat Med. 2008 Apr; 14(4):413-20. Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ. PMID: 18376407.
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    175. Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection. J Virol. 2008 May; 82(10):4785-92. Long BR, Ndhlovu LC, Oksenberg JR, Lanier LL, Hecht FM, Nixon DF, Barbour JD. PMID: 18305035.
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    176. Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals. J Clin Microbiol. 2008 Apr; 46(4):1494-7. Louie B, Wong E, Klausner JD, Liska S, Hecht F, Dowling T, Obeso M, Phillips SS, Pandori MW. PMID: 18234875.
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    177. Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2. J Infect Dis. 2008 Jan 01; 197(1):117-25. Michaëlsson J, Long BR, Loo CP, Lanier LL, Spotts G, Hecht FM, Nixon DF. PMID: 18171294.
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    178. Clinical presentation and diagnosis of primary HIV-1 infection. Curr Opin HIV AIDS. 2008 Jan; 3(1):10-5. Daar ES, Pilcher CD, Hecht FM. PMID: 19372938.
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    179. Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus. Clin Vaccine Immunol. 2008 Jan; 15(1):120-30. Long BR, Michaelsson J, Loo CP, Ballan WM, Vu BA, Hecht FM, Lanier LL, Chapman JM, Nixon DF. PMID: 18003818.
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    180. FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection. J Leukoc Biol. 2008 Feb; 83(2):254-62. Ndhlovu LC, Loo CP, Spotts G, Nixon DF, Hecht FM. PMID: 17982112.
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    181. T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS Pathog. 2007 Nov; 3(11):e165. Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF. PMID: 17997601.
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    182. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. Nat Immunol. 2007 Dec; 8(12):1324-36. Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK. PMID: 17952079.
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    183. Loss of T cell responses following long-term cryopreservation. J Immunol Methods. 2007 Sep 30; 326(1-2):93-115. Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ. PMID: 17707394.
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    184. The relation between symptoms, viral load, and viral load set point in primary HIV infection. . 2007 Aug 01; 45(4):445-8. Kelley CF, Barbour JD, Hecht FM. PMID: 17514014.
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    186. Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy. AIDS Res Hum Retroviruses. 2007 May; 23(5):741-7. Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini SE. PMID: 17531001.
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    187. Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression. PLoS Pathog. 2007 Apr; 3(4):e43. Barbour JD, Sriram U, Caillier SJ, Levy JA, Hecht FM, Oksenberg JR. PMID: 17447840.
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    188. Lessons from an HIV transmission pair. J Infect Dis. 2007 May 01; 195(9):1239-41. Hecht FM, Wolf LE, Lo B. PMID: 17396989.
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    189. Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set point. J Virol. 2007 Jun; 81(11):5759-65. Northfield JW, Loo CP, Barbour JD, Spotts G, Hecht FM, Klenerman P, Nixon DF, Michaëlsson J. PMID: 17376902.
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    190. Symptom management with massage and acupuncture in postoperative cancer patients: a randomized controlled trial. J Pain Symptom Manage. 2007 Mar; 33(3):258-66. Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM. PMID: 17349495.
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    191. Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape. PLoS One. 2007 Feb 21; 2(2):e225. Karlsson AC, Iversen AK, Chapman JM, de Oliviera T, Spotts G, McMichael AJ, Davenport MP, Hecht FM, Nixon DF. PMID: 17311088.
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    192. Lessons from primary HIV infection. Focus. 2007 Feb; 22(2):1-5. Hecht F, Pilcher C. PMID: 17549830.
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    193. Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance. AIDS. 2007 Jan 11; 21(2):239-41. Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM. PMID: 17197817.
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    194. Physicians' communication with patients about adherence to HIV medication in San Francisco and Copenhagen: a qualitative study using Grounded Theory. BMC Health Serv Res. 2006 Dec 04; 6:154. Barfod TS, Hecht FM, Rubow C, Gerstoft J. PMID: 17144910.
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    195. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med. 2006 Dec; 12(12):1365-71. Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. PMID: 17115046.
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    196. Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity. AIDS. 2006 Oct 24; 20(16):2123-5. Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM. PMID: 17053362.
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    197. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol. 2006 Nov; 80(21):10407-18. Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. PMID: 16956949.
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    198. A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection. J Infect Dis. 2006 Sep 15; 194(6):725-33. Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S, AIEDRP Network . PMID: 16941337.
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    199. Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection. AIDS Res Hum Retroviruses. 2006 Aug; 22(8):757-62. Norris PJ, Pappalardo BL, Custer B, Spotts G, Hecht FM, Busch MP. PMID: 16910831.
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    200. A piece of my mind. The CBC. JAMA. 2006 Jul 12; 296(2):149-50. Hecht FM. PMID: 16835410.
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    201. The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response. AIDS Res Hum Retroviruses. 2006 Jul; 22(7):640-7. Killian MS, Norris PJ, Rawal BD, Lebedeva M, Hecht FM, Levy JA, Busch MP. PMID: 16831088.
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    202. Similar changes in plasmacytoid dendritic cell and CD4 T-cell counts during primary HIV-1 infection and treatment. AIDS. 2006 Jun 12; 20(9):1247-52. Killian MS, Fujimura SH, Hecht FM, Levy JA. PMID: 16816552.
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    203. Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses. J Virol. 2006 Jun; 80(12):6155-64. Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM. PMID: 16731954.
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    204. Newly diagnosed HIV infection. N Engl J Med. 2006 Feb 16; 354(7):771-2; author reply 771-2. Chin-Hong PV, Hecht FM, Klausner JD. PMID: 16481652.
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    205. Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection. Clin Infect Dis. 2006 Mar 01; 42(5):700-8. Hare CB, Pappalardo BL, Busch MP, Karlsson AC, Phelps BH, Alexander SS, Bentsen C, Ramstead CA, Nixon DF, Levy JA, Hecht FM. PMID: 16447118.
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    206. Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2. Blood. 2006 Apr 15; 107(8):3081-3. Moll M, Snyder-Cappione J, Spotts G, Hecht FM, Sandberg JK, Nixon DF. PMID: 16368878.
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    207. Seroconversion following nonoccupational postexposure prophylaxis against HIV. Clin Infect Dis. 2005 Nov 15; 41(10):1507-13. Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN. PMID: 16231265.
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    208. Potential herpesvirus interaction during HIV type 1 primary infection. AIDS Res Hum Retroviruses. 2005 Oct; 21(10):869-75. Lennette ET, Busch MP, Hecht FM, Levy JA. PMID: 16225414.
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    209. Resistance testing in drug-naive HIV-infected patients: is it time? Clin Infect Dis. 2005 Nov 01; 41(9):1324-5. Hecht FM, Grant RM. PMID: 16206109.
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    210. Nucleic acid amplification testing for diagnosis of acute HIV infection: has the time come? AIDS. 2005 Aug 12; 19(12):1317-9. Busch MP, Hecht FM. PMID: 16052087.
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    211. New DNA viruses identified in patients with acute viral infection syndrome. J Virol. 2005 Jul; 79(13):8230-6. Jones MS, Kapoor A, Lukashov VV, Simmonds P, Hecht F, Delwart E. PMID: 15956568.
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    212. Randomized, controlled trial of breath therapy for patients with chronic low-back pain. Altern Ther Health Med. 2005 Jul-Aug; 11(4):44-52. Mehling WE, Hamel KA, Acree M, Byl N, Hecht FM. PMID: 16053121.
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    213. Bias control in trials of bodywork: a review of methodological issues. J Altern Complement Med. 2005 Apr; 11(2):333-42. Mehling WE, DiBlasi Z, Hecht F. PMID: 15865501.
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    214. Interleukin-2 therapy restores CD8 cell non-cytotoxic anti-HIV responses in primary infection subjects receiving HAART. AIDS. 2004 Oct 21; 18(15):1991-9. Martinez-Mariño B, Shiboski S, Hecht FM, Kahn JO, Levy JA. PMID: 15577620.
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    215. Persistence of primary drug resistance among recently HIV-1 infected adults. AIDS. 2004 Aug 20; 18(12):1683-9. Barbour JD, Hecht FM, Wrin T, Liegler TJ, Ramstead CA, Busch MP, Segal MR, Petropoulos CJ, Grant RM. PMID: 15280779.
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    216. Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment. Blood. 2004 Dec 01; 104(12):3672-8. Aandahl EM, Quigley MF, Moretto WJ, Moll M, Gonzalez VD, Sönnerborg A, Lindbäck S, Hecht FM, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK. PMID: 15308569.
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    217. Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection. J Infect Dis. 2004 Jul 15; 190(2):251-6. Barbour JD, Hecht FM, Wrin T, Segal MR, Ramstead CA, Liegler TJ, Busch MP, Petropoulos CJ, Hellmann NS, Kahn JO, Grant RM. PMID: 15216458.
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    218. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood. 2004 Aug 15; 104(4):942-7. Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM. PMID: 15117761.
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    219. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol. 2004 Mar; 78(5):2454-9. Aandahl EM, Michaëlsson J, Moretto WJ, Hecht FM, Nixon DF. PMID: 14963140.
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    220. Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. AIDS. 2003 Dec 05; 17(18):2581-91. Altfeld M, Addo MM, Rosenberg ES, Hecht FM, Lee PK, Vogel M, Yu XG, Draenert R, Johnston MN, Strick D, Allen TM, Feeney ME, Kahn JO, Sekaly RP, Levy JA, Rockstroh JK, Goulder PJ, Walker BD. PMID: 14685052.
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    221. Development of a new less-sensitive enzyme immunoassay for detection of early HIV-1 infection. . 2003 Jul 01; 33(3):349-55. Rawal BD, Degula A, Lebedeva L, Janssen RS, Hecht FM, Sheppard HW, Busch MP. PMID: 12843746.
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    223. Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine, and nelfinavir before complete HIV type 1 seroconversion. AIDS Res Hum Retroviruses. 2003 Mar; 19(3):189-99. Smith DE, Kaufmann GR, Kahn JO, Hecht FM, Grey PA, Zaunders JJ, Cunningham PH, Carr A, Duncombe C, Quan DC, Petersen A, Cooper DA. PMID: 12689411.
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    224. Changes in HIV testing after implementation of name-based HIV case surveillance in New Mexico. Am J Public Health. 2002 Nov; 92(11):1757. Lansky A, Lehman JS, Gatwood J, Hecht FM, Fleming PL. PMID: 12406803.
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    225. HIV testing within at-risk populations in the United States and the reasons for seeking or avoiding HIV testing. . 2002 Oct 01; 31(2):202-10. Kellerman SE, Lehman JS, Lansky A, Stevens MR, Hecht FM, Bindman AB, Wortley PM. PMID: 12394799.
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    227. Increased HLA-DR expression on peripheral blood monocytes in subsets of subjects with primary HIV infection is associated with elevated CD4 T-cell apoptosis and CD4 T-cell depletion. . 2002 Jun 01; 30(2):146-53. Gascon RL, Narváez AB, Zhang R, Kahn JO, Hecht FM, Herndier BG, McGrath MS. PMID: 12045676.
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