Gemma Rooney, PhD

TitleLicensing Officer
SchoolUCSF Chancellor/EVC/FAS
DepartmentInnovation Ventures
Address600 16th St
San Francisco CA 94158
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    Gemma joined the Office of Innovation, Technology & Alliances (ITA) in April 2014. Her responsibilities include: evaluating new invention disclosures for patentability/commercial value; guiding campus inventors through the patent assessment/prosecution process; and commercializing UCSF's intellectual property by licensing technologies to appropriate development partners.

    As a biomedical scientist, with postdoctoral training at the University of California San Francisco and the Mayo Clinic College of Medicine, her primary career objective has been to pursue research that could improve patient health and quality of life. She became very interested in translating science concepts into marketable products that could improve patient health outcomes. To this end, she is motivated to apply her scientific expertise to help basic researchers and clinicians to bring their ideas, concepts and products into active patient use.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rooney G, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016 Jan 06; 36(1):142-52. PMID: 26740656; PMCID: PMC4701956.
    2. Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney G, Rauen KA, Weiss LA, Rowitch DH, Ullian EM. Dysregulation of astrocyte extracellular signaling in Costello syndrome. Sci Transl Med. 2015 May 06; 7(286):286ra66. PMID: 25947161; PMCID: PMC4474402.
    3. Madigan NN, Chen BK, Knight AM, Rooney G, Sweeney E, Kinnavane L, Yaszemski MJ, Dockery P, O'Brien T, McMahon SS, Windebank AJ. Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord. Tissue Eng Part A. 2014 Nov; 20(21-22):2985-97. PMID: 24854680; PMCID: PMC4229864.
    4. Donnelly EM, Madigan NN, Rooney G, Knight A, Chen B, Ball B, Kinnavane L, Garcia Y, Dockery P, Fraher J, Strappe PM, Windebank AJ, O'Brien T, McMahon SS. Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord. Cytotherapy. 2012 Nov; 14(10):1235-44. PMID: 23066785.
      View in: PubMed
    5. Chen BK, Knight AM, Madigan NN, Gross L, Dadsetan M, Nesbitt JJ, Rooney G, Currier BL, Yaszemski MJ, Spinner RJ, Windebank AJ. Comparison of polymer scaffolds in rat spinal cord: a step toward quantitative assessment of combinatorial approaches to spinal cord repair. Biomaterials. 2011 Nov; 32(32):8077-86. PMID: 21803415; PMCID: PMC3163757.
    6. Rooney G, Knight AM, Madigan NN, Gross L, Chen B, Giraldo CV, Seo S, Nesbitt JJ, Dadsetan M, Yaszemski MJ, Windebank AJ. Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels. Tissue Eng Part A. 2011 May; 17(9-10):1287-302. PMID: 21198413; PMCID: PMC3079174.
    7. Donnelly EM, Strappe PM, McGinley LM, Madigan NN, Geurts E, Rooney G, Windebank AJ, Fraher J, Dockery P, O'Brien T, McMahon SS. Lentiviral vector-mediated knockdown of the NG2 [corrected] proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar. J Gene Med. 2010 Nov; 12(11):863-72. PMID: 21105148.
      View in: PubMed
    8. Moloney TC, Rooney G, Barry FP, Howard L, Dowd E. Potential of rat bone marrow-derived mesenchymal stem cells as vehicles for delivery of neurotrophins to the Parkinsonian rat brain. Brain Res. 2010 Nov 04; 1359:33-43. PMID: 20732313.
      View in: PubMed
    9. McMahon SS, Albermann S, Rooney G, Shaw G, Garcia Y, Sweeney E, Hynes J, Dockery P, O'Brien T, Windebank AJ, Allsopp TE, Barry FP. Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury. Cytotherapy. 2010 May; 12(3):313-25. PMID: 20370348.
      View in: PubMed
    10. Rooney G, Endo T, Ameenuddin S, Chen B, Vaishya S, Gross L, Schiefer TK, Currier BL, Spinner RJ, Yaszemski MJ, Windebank AJ. Importance of the vasculature in cyst formation after spinal cord injury. J Neurosurg Spine. 2009 Oct; 11(4):432-7. PMID: 19929340; PMCID: PMC2981802.
    11. Rooney G, McMahon SS, Ritter T, Garcia Y, Moran C, Madigan NN, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP. Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells. Tissue Eng Part A. 2009 Oct; 15(10):3049-59. PMID: 19335061.
      View in: PubMed
    12. Olson HE, Rooney G, Gross L, Nesbitt JJ, Galvin KE, Knight A, Chen B, Yaszemski MJ, Windebank AJ. Neural stem cell- and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord. Tissue Eng Part A. 2009 Jul; 15(7):1797-805. PMID: 19191513; PMCID: PMC2792101.
    13. McMahon SS, Albermann S, Rooney G, Moran C, Hynes J, Garcia Y, Dockery P, O'Brien T, Windebank AJ, Barry FP. Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury. J Anat. 2009 Sep; 215(3):267-79. PMID: 19558472; PMCID: PMC2750760.
    14. Rooney G, Howard L, O'Brien T, Windebank AJ, Barry FP. Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation. Stem Cells Dev. 2009 Apr; 18(3):387-98. PMID: 18554089.
      View in: PubMed
    15. Krych AJ, Rooney G, Chen B, Schermerhorn TC, Ameenuddin S, Gross L, Moore MJ, Currier BL, Spinner RJ, Friedman JA, Yaszemski MJ, Windebank AJ. Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord. Acta Biomater. 2009 Sep; 5(7):2551-9. PMID: 19409869; PMCID: PMC2731813.
    16. Rooney G, Vaishya S, Ameenuddin S, Currier BL, Schiefer TK, Knight A, Chen B, Mishra PK, Spinner RJ, Macura SI, Yaszemski MJ, Windebank AJ. Rigid fixation of the spinal column improves scaffold alignment and prevents scoliosis in the transected rat spinal cord. Spine (Phila Pa 1976). 2008 Nov 15; 33(24):E914-9. PMID: 19011531; PMCID: PMC2773001.
    17. Rooney G, Moran C, McMahon SS, Ritter T, Maenz M, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP. Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate. Tissue Eng Part A. 2008 May; 14(5):681-90. PMID: 18402551.
      View in: PubMed
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