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Geoffrey Manley, MD, PhD

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-8300
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, San Francisco, CAPostdoc Fellowship1999Molecular Biophysics
    Cornell University Medical College, New York, NYMD1995Medicine
    Memorial Sloan Kettering Cancer Center, New York, NYPostdoc Fellowship1995Neuroscience
    Cornell University, New York, NYPhD1994Neuroscience
    University of Kentucky, Lexington, KYBS1988Biology

    Collapse Overview 
    Collapse Overview
    Dr. Manley is Chief of Neurosurgery at Zuckerberg San Francisco General Hospital and Professor and Vice Chairman of Neurological Surgery at UCSF. He is a trauma neurosurgeon and Co-Director of the Brain and Spinal Injury Center. Dr. Manley's research interests range from molecular aspects of traumatic brain injury (TBI) to the clinical care of TBI victims. This work spans from the laboratory to the bedside in an effort to develop translational models and data repositories to improve the diagnosis, prognosis and treatment of mild to severe brain injuries. He is the Contact Principal Investigator for both the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) U01 research project funded by the National Institute of Neurological Disorders and Strokee and the Department of Defense TBI Endpoints Development (TED) Initiative. Dr. Manley is also the contact PI of the recently awarded TRACK-TBI Network that will soon be launching innovative phase 2 clinical TBI trials.

    Collapse Research 
    Collapse Research Activities and Funding
    Transforming Research and Clinical Knowledge in Traumatic Brain Injury Network (TRACK-TBI NET)
    Medical Technology Enterprise Consortium/DoD 2018-674Sep 14, 2018 - Nov 30, 2023
    Role: Principal Investigator
    TRACK-TBI Precision Medicine - Pathomechanistic Classification of Traumatic Brain Injury: The Bridge to Targeted Therapies
    DOD US Army Med. Res. Acq. Activity W81XWH-18-2-0042Aug 1, 2018 - Jul 31, 2021
    Role: Principal Investigator
    Transforming Research and Clinical Knowledge in Traumatic Brain Injury
    NIH/NINDS U01NS086090Apr 1, 2015 - Mar 31, 2016
    Role: Principal Investigator
    Traumatic Brain Injury Endpoints Development (TED) Initiative
    DOD US Army Med. Res. Acq. Activity W81XWH-14-2-0176Sep 30, 2014 - Sep 29, 2019
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold. JAMA Neurol. 2020 Jun 15. Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann L, Saigal R, Ding Q, Hirschi R, Zeiler FA, Ferguson A, Manley G. PMID: 32539101.
      View in: PubMed   Mentions:    Fields:    
    2. Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI): an overview of initial enrollment and demographics. Neurosurg Focus. 2020 05 01; 48(5):E6. Tsolinas RE, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris MH, Yue JK, Winkler EA, Suen CG, Pascual LU, Ferguson AR, Huie JR, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, Kyritsis N, Haefeli J, Weinstein PR, de Almeida Neto CA, Kuo YH, Taggard D, Talbott JF, Whetstone WD, Manley GT, Bresnahan JC, Beattie MS, Dhall SS. PMID: 32357323.
      View in: PubMed   Mentions:    Fields:    
    3. Clinical Predictors of 3- and 6-Month Outcome for Mild Traumatic Brain Injury Patients with a Negative Head CT Scan in the Emergency Department: A TRACK-TBI Pilot Study. Brain Sci. 2020 May 01; 10(5). Madhok DY, Yue JK, Sun X, Suen CG, Coss NA, Jain S, Manley GT. PMID: 32369967.
      View in: PubMed   Mentions:
    4. Invariance of the Bifactor Structure of Mild Traumatic Brain Injury (mTBI) Symptoms on the Rivermead Postconcussion Symptoms Questionnaire Across Time, Demographic Characteristics, and Clinical Groups: A TRACK-TBI Study. Assessment. 2020 Apr 24; 1073191120913941. Agtarap S, Kramer MD, Campbell-Sills L, Yuh E, Mukherjee P, Manley GT, McCrea MA, Dikmen S, Giacino JT, Stein MB, Nelson LD. PMID: 32326739.
      View in: PubMed   Mentions:    Fields:    
    5. Substance use on admission toxicology screen is associated with peri-injury factors and six-month outcome after traumatic brain injury: A TRACK-TBI Pilot study. J Clin Neurosci. 2020 May; 75:149-156. Yue JK, Phelps RRL, Winkler EA, Deng H, Upadhyayula PS, Vassar MJ, Madhok DY, Schnyer DM, Puccio AM, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT. PMID: 32173156.
      View in: PubMed   Mentions:    Fields:    
    6. Sideline Concussion Assessment: The Current State of the Art. Neurosurgery. 2020 Mar 03. Yue JK, Phelps RRL, Chandra A, Winkler EA, Manley GT, Berger MS. PMID: 32126135.
      View in: PubMed   Mentions:    Fields:    
    7. Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies. J Neurotrauma. 2020 Jun 01; 37(11):1283-1290. Meeuws S, Yue JK, Huijben JA, Nair N, Lingsma HF, Bell MJ, Manley GT, Maas AIR. PMID: 32000562.
      View in: PubMed   Mentions:    Fields:    
    8. Revisits, readmissions, and outcomes for pediatric traumatic brain injury in California, 2005-2014. PLoS One. 2020; 15(1):e0227981. Hsia RY, Mannix RC, Guo J, Kornblith AE, Lin F, Sokolove PE, Manley GT. PMID: 31978188.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med. 2020 May; 46(5):919-929. Chesnut R, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK, Meyfroidt G, Michael DB, Oddo M, Okonkwo D, Patel M, Robertson C, Rosenfeld JV, Rubiano AM, Sahuquillo J, Servadei F, Shutter L, Stein D, Stocchetti N, Taccone FS, Timmons S, Tsai E, Ullman JS, Vespa P, Videtta W, Wright DW, Zammit C, Hawryluk GWJ. PMID: 31965267.
      View in: PubMed   Mentions: 1     Fields:    
    10. Modeling the characteristics of spontaneous otoacoustic emissions in lizards. Hear Res. 2020 Jan; 385:107840. Wit HP, Manley GA, van Dijk P. PMID: 31760263.
      View in: PubMed   Mentions:    Fields:    
    11. Functional Status Examination Yields Higher Measurement Precision of Functional Limitations after Traumatic Injury than the Glasgow Outcome Scale-Extended: A Preliminary Study. J Neurotrauma. 2020 Feb 15; 37(4):675-679. Nelson LD, Brett BL, Magnus BE, Balsis S, McCrea MA, Manley GT, Temkin N, Dikmen S. PMID: 31663425.
      View in: PubMed   Mentions:    Fields:    
    12. Suppression tuning of spontaneous otoacoustic emissions in the barn owl (Tyto alba). Hear Res. 2020 Jan; 385:107835. Engler S, Köppl C, Manley GA, de Kleine E, van Dijk P. PMID: 31710933.
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    13. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med. 2019 12; 45(12):1783-1794. Hawryluk GWJ, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK, Meyfroidt G, Michael DB, Oddo M, Okonkwo D, Patel M, Robertson C, Rosenfeld JV, Rubiano AM, Sahuquillo J, Servadei F, Shutter L, Stein D, Stocchetti N, Taccone FS, Timmons S, Tsai E, Ullman JS, Vespa P, Videtta W, Wright DW, Zammit C, Chesnut RM. PMID: 31659383.
      View in: PubMed   Mentions: 2     Fields:    
    14. The Functional Status Examination in Mild Traumatic Brain Injury: A TRACK-TBI Sub-Study. Arch Clin Neuropsychol. 2019 Oct 24; 34(7):1165-1174. Zahniser E, Temkin NR, Machamer J, Barber J, Manley GT, Markowitz AJ, Dikmen SS. PMID: 30608522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. Lancet Neurol. 2019 10; 18(10):923-934. Steyerberg EW, Wiegers E, Sewalt C, Buki A, Citerio G, De Keyser V, Ercole A, Kunzmann K, Lanyon L, Lecky F, Lingsma H, Manley G, Nelson D, Peul W, Stocchetti N, von Steinbüchel N, Vande Vyvere T, Verheyden J, Wilson L, Maas AIR, Menon DK. PMID: 31526754.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Clinical Implementation of Novel Spinal Cord Perfusion Pressure Protocol in Acute Traumatic Spinal Cord Injury at U.S. Level I Trauma Center: TRACK-SCI Study. World Neurosurg. 2020 Jan; 133:e391-e396. Yue JK, Hemmerle DD, Winkler EA, Thomas LH, Fernandez XD, Kyritsis N, Pan JZ, Pascual LU, Singh V, Weinstein PR, Talbott JF, Huie JR, Ferguson AR, Whetstone WD, Manley GT, Beattie MS, Bresnahan JC, Mummaneni PV, Dhall SS. PMID: 31526882.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Pediatric firearm-related traumatic brain injury in United States trauma centers. J Neurosurg Pediatr. 2019 Sep 06; 1-11. Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE. PMID: 31491751.
      View in: PubMed   Mentions:    Fields:    
    18. The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data. Front Neuroinform. 2019; 13:60. Kim H, Irimia A, Hobel SM, Pogosyan M, Tang H, Petrosyan P, Blanco REC, Duffy BA, Zhao L, Crawford KL, Liew SL, Clark K, Law M, Mukherjee P, Manley GT, Van Horn JD, Toga AW. PMID: 31555116.
      View in: PubMed   Mentions:
    19. Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study. Lancet Neurol. 2019 10; 18(10):953-961. Yue JK, Yuh EL, Korley FK, Winkler EA, Sun X, Puffer RC, Deng H, Choy W, Chandra A, Taylor SR, Ferguson AR, Huie JR, Rabinowitz M, Puccio AM, Mukherjee P, Vassar MJ, Wang KKW, Diaz-Arrastia R, Okonkwo DO, Jain S, Manley GT. PMID: 31451409.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery. 2019 08 01; 85(2):E401-E402. Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS. PMID: 31173137.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery. 2019 08 01; 85(2):199-203. Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS. PMID: 30496474.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study. JAMA Neurol. 2019 Jun 03. Nelson LD, Temkin NR, Dikmen S, Barber J, Giacino JT, Yuh E, Levin HS, McCrea MA, Stein MB, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, Crawford K, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson A, Foreman B, Gardner R, Gaudette E, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Jain S, Korley F, Kramer J, Kreitzer N, Lindsell C, Machamer J, Madden C, Martin A, McAllister T, Merchant R, Noel F, Palacios E, Perl D, Puccio A, Rabinowitz M, Robertson CS, Rosand J, Sander A, Satris G, Schnyer D, Seabury S, Sherer M, Taylor S, Toga A, Valadka A, Vassar MJ, Vespa P, Wang K, Yue JK, Zafonte R. PMID: 31157856.
      View in: PubMed   Mentions: 1     Fields:    
    23. Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement. Acta Neurochir (Wien). 2019 07; 161(7):1261-1274. Hutchinson PJ, Kolias AG, Tajsic T, Adeleye A, Aklilu AT, Apriawan T, Bajamal AH, Barthélemy EJ, Devi BI, Bhat D, Bulters D, Chesnut R, Citerio G, Cooper DJ, Czosnyka M, Edem I, El-Ghandour NMF, Figaji A, Fountas KN, Gallagher C, Hawryluk GWJ, Iaccarino C, Joseph M, Khan T, Laeke T, Levchenko O, Liu B, Liu W, Maas A, Manley GT, Manson P, Mazzeo AT, Menon DK, Michael DB, Muehlschlegel S, Okonkwo DO, Park KB, Rosenfeld JV, Rosseau G, Rubiano AM, Shabani HK, Stocchetti N, Timmons SD, Timofeev I, Uff C, Ullman JS, Valadka A, Waran V, Wells A, Wilson MH, Servadei F. PMID: 31134383.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Divergent Six Month Functional Recovery Trajectories and Predictors after Traumatic Brain Injury: Novel Insights from the Citicoline Brain Injury Treatment Trial Study. J Neurotrauma. 2019 09 01; 36(17):2521-2532. Gardner RC, Cheng J, Ferguson AR, Boylan R, Boscardin J, Zafonte RD, Manley GT. PMID: 30909795.
      View in: PubMed   Mentions:    Fields:    
    25. Diagnosing the GOSE: Structural and Psychometric Properties Using Item Response Theory, a TRACK-TBI Pilot Study. J Neurotrauma. 2019 09 01; 36(17):2493-2505. Ranson J, Magnus BE, Temkin N, Dikmen S, Giacino JT, Okonkwo DO, Valadka AB, Manley GT, Nelson LD. PMID: 30907261.
      View in: PubMed   Mentions: 1     Fields:    
    26. Functional Status Examination versus Glasgow Outcome Scale Extended as Outcome Measures in Traumatic Brain Injuries: How Do They Compare? J Neurotrauma. 2019 08 15; 36(16):2423-2429. Dikmen S, Machamer J, Manley GT, Yuh EL, Nelson LD, Temkin NR. PMID: 30827167.
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    27. The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury: Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial. Crit Care Med. 2019 05; 47(5):623-631. Merck LH, Yeatts SD, Silbergleit R, Manley GT, Pauls Q, Palesch Y, Conwit R, Le Roux P, Miller J, Frankel M, Wright DW. PMID: 30730438.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. A Comparison of Satisfaction With Life and the Glasgow Outcome Scale-Extended After Traumatic Brain Injury: An Analysis of the TRACK-TBI Pilot Study. J Head Trauma Rehabil. 2019 May/Jun; 34(3):E10-E17. Kreitzer NP, Hart K, Lindsell CJ, Manley GT, Dikmen SS, Ratcliff JJ, Yue JK, Adeoye OM. PMID: 30499935.
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    29. Age and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study. Neurol Res. 2019 Jul; 41(7):609-623. Yue JK, Levin HS, Suen CG, Morrissey MR, Runyon SJ, Winkler EA, Puffer RC, Deng H, Robinson CK, Rick JW, Phelps RRL, Sharma S, Taylor SR, Vassar MJ, Cnossen MC, Lingsma HF, Gardner RC, Temkin NR, Barber J, Dikmen SS, Yuh EL, Mukherjee P, Stein MB, Cage TA, Valadka AB, Okonkwo DO, Manley GT. PMID: 31007155.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study. Front Neurol. 2019; 10:343. Yue JK, Cnossen MC, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, Manley GT. PMID: 31024436.
      View in: PubMed   Mentions:
    31. Characterizing the Response to Cerebrospinal Fluid Drainage in Patients with an External Ventricular Drain: The Pressure Equalization Ratio. Neurocrit Care. 2019 04; 30(2):340-347. Candanedo C, Doron O, Hemphill JC, Ramirez de Noriega F, Manley GT, Patal R, Rosenthal G. PMID: 30251075.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study. JAMA Psychiatry. 2019 03 01; 76(3):249-258. Stein MB, Jain S, Giacino JT, Levin H, Dikmen S, Nelson LD, Vassar MJ, Okonkwo DO, Diaz-Arrastia R, Robertson CS, Mukherjee P, McCrea M, Mac Donald CL, Yue JK, Yuh E, Sun X, Campbell-Sills L, Temkin N, Manley GT, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, Crawford K, Diaz-Arrastia R, Dikmen S, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson A, Foreman B, Gardner R, Gaudette E, Giacino JT, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Jain S, Korley F, Kramer J, Kreitzer N, Levin H, Lindsell C, Machamer J, Madden C, Martin A, McAllister T, McCrea M, Merchant R, Mukherjee P, Nelson LD, Noel F, Okonkwo DO, Palacios E, Perl D, Puccio A, Rabinowitz M, Robertson CS, Rosand J, Sander A, Satris G, Schnyer D, Seabury S, Sherer M, Stein MB, Taylor S, Toga A, Temkin N, Valadka A, Vassar MJ, Vespa P, Wang K, Yue JK, Yuh E, Zafonte R. PMID: 30698636.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Value of aggressive surgical and intensive care unit in elderly patients with traumatic spinal cord injury. Neurosurg Focus. 2019 03 01; 46(3):E3. Lau D, Dalle Ore CL, Tarapore PE, Huang M, Manley G, Singh V, Mummaneni PV, Beattie M, Bresnahan J, Ferguson AR, Talbott JF, Whetstone W, Dhall SS. PMID: 30835676.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. The Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study. J Neurotrauma. 2019 06; 36(11):1786-1793. Zahniser E, Nelson LD, Dikmen SS, Machamer JE, Stein MB, Yuh E, Manley GT, Temkin NR. PMID: 30543138.
      View in: PubMed   Mentions:    Fields:    
    35. Rehabilitation Trajectories and Outcomes in Individuals With Mild Traumatic Brain Injury and Psychiatric Histories: A TRACK-TBI Pilot Study. J Head Trauma Rehabil. 2019 Jan/Feb; 34(1):36-44. Bertisch H, Satris G, Temkin N, Barber J, Manley GT. PMID: 29863617.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Ten-year trends in traumatic brain injury: a retrospective cohort study of California emergency department and hospital revisits and readmissions. BMJ Open. 2018 12 14; 8(12):e022297. Hsia RY, Markowitz AJ, Lin F, Guo J, Madhok DY, Manley GT. PMID: 30552250.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Military-related risk factors for dementia. Alzheimers Dement. 2018 12; 14(12):1651-1662. Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, Weiner M, Wellington C, Yaffe K, Bain L, Pacifico AM, Carrillo MC. PMID: 30415806.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    38. State of the Science on Pediatric Mild Traumatic Brain Injury: Progress Toward Clinical Translation. JAMA Pediatr. 2018 11 01; 172(11):e182846. McCrea M, Manley G. PMID: 30193296.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. A swine model of intracellular cerebral edema - Cerebral physiology and intracranial compliance. J Clin Neurosci. 2018 Dec; 58:192-199. Ramirez de Noriega F, Manley GT, Moscovici S, Itshayek E, Tamir I, Fellig Y, Shkara RA, Rosenthal G. PMID: 30454689.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    40. Analysis of high-frequency PbtO2 measures in traumatic brain injury: insights into the treatment threshold. J Neurosurg. 2018 Oct 01; 1-11. Hirschi R, Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann LL, Saigal R, Ding Q, Ferguson AR, Manley G. PMID: 30497191.
      View in: PubMed   Mentions: 1     Fields:    
    41. Testing a Multivariate Proteomic Panel for Traumatic Brain Injury Biomarker Discovery: A TRACK-TBI Pilot Study. J Neurotrauma. 2019 01 01; 36(1):100-110. Huie JR, Diaz-Arrastia R, Yue JK, Sorani MD, Puccio AM, Okonkwo DO, Manley GT, Ferguson AR. PMID: 30084741.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Temporal lobe contusions on computed tomography are associated with impaired 6-month functional recovery after mild traumatic brain injury: a TRACK-TBI study. Neurol Res. 2018 Nov; 40(11):972-981. Yue JK, Winkler EA, Puffer RC, Deng H, Phelps RRL, Wagle S, Morrissey MR, Rivera EJ, Runyon SJ, Vassar MJ, Taylor SR, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Schnyer DM, Puccio AM, Valadka AB, Okonkwo DO, Manley GT. PMID: 30175944.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. Adult Firearm-Related Traumatic Brain Injury in United States Trauma Centers. J Neurotrauma. 2019 01 15; 36(2):322-337. Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE. PMID: 29855212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda. J Neurotrauma. 2018 11 15; 35(22):2615-2631. Wickwire EM, Schnyer DM, Germain A, Williams SG, Lettieri CJ, McKeon AB, Scharf SM, Stocker R, Albrecht J, Badjatia N, Markowitz AJ, Manley GT. PMID: 29877132.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Prediction of Persistent Post-Concussion Symptoms after Mild Traumatic Brain Injury. J Neurotrauma. 2018 11 15; 35(22):2691-2698. Cnossen MC, van der Naalt J, Spikman JM, Nieboer D, Yue JK, Winkler EA, Manley GT, von Steinbuechel N, Polinder S, Steyerberg EW, Lingsma HF. PMID: 29690799.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    46. Performance Evaluation of a Multiplex Assay for Simultaneous Detection of Four Clinically Relevant Traumatic Brain Injury Biomarkers. J Neurotrauma. 2018 Jul 23. Korley FK, Yue JK, Wilson DH, Hrusovsky K, Diaz-Arrastia R, Ferguson AR, Yuh EL, Mukherjee P, Wang KKW, Valadka AB, Puccio AM, Okonkwo DO, Manley GT. PMID: 29690824.
      View in: PubMed   Mentions: 2     Fields:    
    47. Sub-classifying patients with mild traumatic brain injury: A clustering approach based on baseline clinical characteristics and 90-day and 180-day outcomes. PLoS One. 2018; 13(7):e0198741. Si B, Dumkrieger G, Wu T, Zafonte R, Valadka AB, Okonkwo DO, Manley GT, Wang L, Dodick DW, Schwedt TJ, Li J. PMID: 29995912.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    48. Age-Related Differences in Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein and Tau for Identifying Acute Intracranial Trauma on Computed Tomography: A TRACK-TBI Study. J Neurotrauma. 2018 10 15; 35(20):2341-2350. Gardner RC, Rubenstein R, Wang KKW, Korley FK, Yue JK, Yuh EL, Mukherje P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT. PMID: 29717620.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. Predictors of 30-Day Outcomes in Octogenarians with Traumatic C2 Fractures Undergoing Surgery. World Neurosurg. 2018 Aug; 116:e1214-e1222. Yue JK, Ordaz A, Winkler EA, Deng H, Suen CG, Burke JF, Chan AK, Manley GT, Dhall SS, Tarapore PE. PMID: 29886301.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study. Brain Inj. 2018; 32(9):1071-1078. Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT. PMID: 29863894.
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    51. Motor Evoked Potentials Correlate With Magnetic Resonance Imaging and Early Recovery After Acute Spinal Cord Injury. Neurosurgery. 2018 06 01; 82(6):870-876. Dhall SS, Haefeli J, Talbott JF, Ferguson AR, Readdy WJ, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Whetstone WD. PMID: 28973360.
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    52. Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and Concussion: Results From the TRACK-TBI Study. JAMA Netw Open. 2018 05 18; 1(1):e180210. Seabury SA, Gaudette É, Goldman DP, Markowitz AJ, Brooks J, McCrea MA, Okonkwo DO, Manley GT, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, Crawford K, Diaz-Arrastia R, Dikmen S, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson A, Foreman B, Gardner R, Giacino J, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Jain S, Korley F, Kramer J, Kreitzer N, Levin H, Lindsell C, Machamer J, Madden C, Martin A, McAllister T, Merchant R, Mukherjee P, Nelson L, Noel F, Palacios E, Perl D, Puccio A, Rabinowitz M, Robertson C, Rosand J, Sander A, Satris G, Schnyer D, Sherer M, Stein M, Taylor S, Temkin N, Toga A, Valadka A, Vassar M, Vespa P, Wang K, Yue J, Yuh E, Zafonte R. PMID: 30646055.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    53. Optimizing Outcome Assessment in Multicenter TBI Trials: Perspectives From TRACK-TBI and the TBI Endpoints Development Initiative. J Head Trauma Rehabil. 2018 May/Jun; 33(3):147-157. Bodien YG, McCrea M, Dikmen S, Temkin N, Boase K, Machamer J, Taylor SR, Sherer M, Levin H, Kramer JH, Corrigan JD, McAllister TW, Whyte J, Manley GT, Giacino JT. PMID: 29385010.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    54. Functional Status Examination in Patients with Moderate-to-Severe Traumatic Brain Injuries. J Neurotrauma. 2018 05 15; 35(10):1132-1137. Machamer J, Temkin NR, Manley GT, Dikmen S. PMID: 29415608.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    55. Utility of Repeat Head CT in Patients with Blunt Traumatic Brain Injury Presenting with Small Isolated Falcine or Tentorial Subdural Hematomas. AJNR Am J Neuroradiol. 2018 Apr; 39(4):654-657. Devulapalli KK, Talbott JF, Narvid J, Gean A, Rehani B, Manley G, Uzelac A, Yuh E, Huang MC. PMID: 29496726.
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    56. Cerebral blood vessel damage in traumatic brain injury. Clin Biomech (Bristol, Avon). 2019 04; 64:98-113. Monson KL, Converse MI, Manley GT. PMID: 29478776.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    57. Geriatric Traumatic Brain Injury: Epidemiology, Outcomes, Knowledge Gaps, and Future Directions. J Neurotrauma. 2018 Apr 01; 35(7):889-906. Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT. PMID: 29212411.
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    58. The Berlin International Consensus Meeting on Concussion in Sport. Neurosurgery. 2018 02 01; 82(2):232-236. Davis GA, Ellenbogen RG, Bailes J, Cantu RC, Johnston KM, Manley GT, Nagahiro S, Sills A, Tator CH, McCrory P. PMID: 29106653.
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    59. An update on diagnostic and prognostic biomarkers for traumatic brain injury. Expert Rev Mol Diagn. 2018 02; 18(2):165-180. Wang KK, Yang Z, Zhu T, Shi Y, Rubenstein R, Tyndall JA, Manley GT. PMID: 29338452.
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    60. Reply to: Prehospital Intubation: Further Confounders in Trial Results. Prehosp Emerg Care. 2018 Jul-Aug; 22(4):537. Nuño T, Denninghoff KR, Pauls Q, Yeatts SD, Silbergleit R, Palesch YY, Merck LH, Manley G, Wright DW. PMID: 29338483.
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    61. Preinjury employment status as a risk factor for symptomatology and disability in mild traumatic brain injury: A TRACK-TBI analysis. NeuroRehabilitation. 2018; 43(2):169-182. Yue JK, Rick JW, Morrissey MR, Taylor SR, Deng H, Suen CG, Vassar MJ, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Gardner RC, Valadka AB, Okonkwo DO, Cage TA, Manley GT. PMID: 30040754.
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    62. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 2017 12; 16(12):987-1048. Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A, Bragge P, Brazinova A, Büki A, Chesnut RM, Citerio G, Coburn M, Cooper DJ, Crowder AT, Czeiter E, Czosnyka M, Diaz-Arrastia R, Dreier JP, Duhaime AC, Ercole A, van Essen TA, Feigin VL, Gao G, Giacino J, Gonzalez-Lara LE, Gruen RL, Gupta D, Hartings JA, Hill S, Jiang JY, Ketharanathan N, Kompanje EJO, Lanyon L, Laureys S, Lecky F, Levin H, Lingsma HF, Maegele M, Majdan M, Manley G, Marsteller J, Mascia L, McFadyen C, Mondello S, Newcombe V, Palotie A, Parizel PM, Peul W, Piercy J, Polinder S, Puybasset L, Rasmussen TE, Rossaint R, Smielewski P, Söderberg J, Stanworth SJ, Stein MB, von Steinbüchel N, Stewart W, Steyerberg EW, Stocchetti N, Synnot A, Te Ao B, Tenovuo O, Theadom A, Tibboel D, Videtta W, Wang KKW, Williams WH, Wilson L, Yaffe K. PMID: 29122524.
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    63. Safety and effectiveness of early chemical deep venous thrombosis prophylaxis after spinal cord injury: pilot prospective data. Neurosurg Focus. 2017 Nov; 43(5):E21. DiGiorgio AM, Tsolinas R, Alazzeh M, Haefeli J, Talbott JF, Ferguson AR, Bresnahan JC, Beattie MS, Manley GT, Whetstone WD, Mummaneni PV, Dhall SS. PMID: 29088948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    64. The diagnostic values of UCH-L1 in traumatic brain injury: A meta-analysis. Brain Inj. 2018; 32(1):1-17. Shahjouei S, Sadeghi-Naini M, Yang Z, Kobeissy F, Rathore D, Shokraneh F, Blackburn S, Manley GT, Wang KKW. PMID: 29087740.
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    65. Infographic: Consensus statement on concussion in sport. Br J Sports Med. 2017 Nov; 51(21):1557-1558. McCrory P, Meeuwisse W, Dvorak J, Aubry M, Bailes J, Broglio S, Cantu RC, Cassidy D, Echemendia RJ, Castellani RJ, Davis GA, Ellenbogen R, Emery C, Engebretsen L, Feddermann-Demont N, Giza CC, Guskiewicz KM, Herring S, Iverson GL, Johnston KM, Kissick J, Kutcher J, Leddy JJ, Maddocks D, Makdissi M, Manley G, McCrea M, Meehan WP, Nagahiro S, Patricios J, Putukian M, Schneider KJ, Sills A, Tator CH, Turner M, Vos PE. PMID: 28899991.
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    66. Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau-Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers. JAMA Neurol. 2017 09 01; 74(9):1063-1072. Rubenstein R, Chang B, Yue JK, Chiu A, Winkler EA, Puccio AM, Diaz-Arrastia R, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Davies P, Agarwal S, Lin F, Sarkis G, Yadikar H, Yang Z, Manley GT, Wang KKW, Cooper SR, Dams-O'Connor K, Borrasso AJ, Inoue T, Maas AIR, Menon DK, Schnyer DM, Vassar MJ. PMID: 28738126.
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    67. Apolipoprotein E epsilon 4 (APOE-e4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury. Brain Behav. 2017 09; 7(9):e00791. Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT. PMID: 28948085.
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    68. Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury. J Clin Neurosci. 2017 Nov; 45:293-298. Yue JK, Ngwenya LB, Upadhyayula PS, Deng H, Winkler EA, Burke JF, Lee YM, Robinson CK, Ferguson AR, Lingsma HF, Cnossen MC, Pirracchio R, Korley FK, Vassar MJ, Yuh EL, Mukherjee P, Gordon WA, Valadka AB, Okonkwo DO, Manley GT. PMID: 28789959.
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    69. Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence. Brain Sci. 2017 Jul 25; 7(8). Yue JK, Burke JF, Upadhyayula PS, Winkler EA, Deng H, Robinson CK, Pirracchio R, Suen CG, Sharma S, Ferguson AR, Ngwenya LB, Stein MB, Manley GT, Tarapore PE. PMID: 28757598.
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    70. Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury. J Neurosurg. 2018 05; 128(5):1530-1537. Ngwenya LB, Suen CG, Tarapore PE, Manley GT, Huang MC. PMID: 28644101.
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    71. Validating Multidimensional Outcome Assessment Using the TBI Common Data Elements: An Analysis of the TRACK-TBI Pilot Sample. J Neurotrauma. 2017 Jun 08. Nelson LD, Ranson J, Ferguson AR, Giacino J, Okonkwo DO, Valadka A, Manley G, McCrea M. PMID: 28595478.
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    72. Morbidity and Mortality Associated with Surgery of Traumatic C2 Fractures in Octogenarians. Neurosurgery. 2017 Jun 01; 80(6):854-862. Dhall SS, Yue JK, Winkler EA, Mummaneni PV, Manley GT, Tarapore PE. PMID: 28368543.
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    73. Prehospital Intubation is Associated with Favorable Outcomes and Lower Mortality in ProTECT III. Prehosp Emerg Care. 2017 Sep-Oct; 21(5):539-544. Denninghoff KR, Nuño T, Pauls Q, Yeatts SD, Silbergleit R, Palesch YY, Merck LH, Manley GT, Wright DW. PMID: 28489506.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    74. A systematic review of potential long-term effects of sport-related concussion. Br J Sports Med. 2017 Jun; 51(12):969-977. Manley G, Gardner AJ, Schneider KJ, Guskiewicz KM, Bailes J, Cantu RC, Castellani RJ, Turner M, Jordan BD, Randolph C, Dvorák J, Hayden KA, Tator CH, McCrory P, Iverson GL. PMID: 28455362.
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    75. Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review. Br J Sports Med. 2017 Jun; 51(12):919-929. McCrea M, Meier T, Huber D, Ptito A, Bigler E, Debert CT, Manley G, Menon D, Chen JK, Wall R, Schneider KJ, McAllister T. PMID: 28455364.
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    76. Consensus statement on concussion in sport-the 5th international conference on concussion in sport held in Berlin, October 2016. Br J Sports Med. 2017 Jun; 51(11):838-847. McCrory P, Meeuwisse W, Dvorák J, Aubry M, Bailes J, Broglio S, Cantu RC, Cassidy D, Echemendia RJ, Castellani RJ, Davis GA, Ellenbogen R, Emery C, Engebretsen L, Feddermann-Demont N, Giza CC, Guskiewicz KM, Herring S, Iverson GL, Johnston KM, Kissick J, Kutcher J, Leddy JJ, Maddocks D, Makdissi M, Manley GT, McCrea M, Meehan WP, Nagahiro S, Patricios J, Putukian M, Schneider KJ, Sills A, Tator CH, Turner M, Vos PE. PMID: 28446457.
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    77. The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a Public-Private Regulatory Collaboration to Accelerate Diagnosis and Treatment of Traumatic Brain Injury. J Neurotrauma. 2017 Mar 31. Manley GT, MacDonald CL, Markowitz A, Stephenson D, Robbins A, Gardner RC, Winkler EA, Bodien Y, Taylor S, Yue JK, Kannan L, Kumar A, McCrea M, Wang KKW. PMID: 28363253.
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    78. Development of a Prediction Model for Post-Concussive Symptoms following Mild Traumatic Brain Injury: A TRACK-TBI Pilot Study. J Neurotrauma. 2017 Mar 27. Cnossen MC, Winkler EA, Yue JK, Okonkwo DO, Valadka A, Steyerberg EW, Lingsma H, Manley GT. PMID: 28343409.
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    79. Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis. PLoS One. 2017; 12(3):e0169490. Nielson JL, Cooper SR, Yue JK, Sorani MD, Inoue T, Yuh EL, Mukherjee P, Petrossian TC, Paquette J, Lum PY, Carlsson GE, Vassar MJ, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Manley GT, Ferguson AR. PMID: 28257413.
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    80. Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury. J Neurotrauma. 2017 04 15; 34(8):1546-1557. Palacios EM, Yuh EL, Chang YS, Yue JK, Schnyer DM, Okonkwo DO, Valadka AB, Gordon WA, Maas AIR, Vassar M, Manley GT, Mukherjee P. PMID: 28085565.
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    81. Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome. Brain Inj. 2017; 31(13-14):1820-1829. Yue JK, Winkler EA, Sharma S, Vassar MJ, Ratcliff JJ, Korley FK, Seabury SA, Ferguson AR, Lingsma HF, Deng H, Meeuws S, Adeoye OM, Rick JW, Robinson CK, Duarte SM, Yuh EL, Mukherjee P, Dikmen SS, McAllister TW, Diaz-Arrastia R, Valadka AB, Gordon WA, Okonkwo DO, Manley GT. PMID: 29166203.
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    82. Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury. AJNR Am J Neuroradiol. 2017 Mar; 38(3):648-655. Haefeli J, Mabray MC, Whetstone WD, Dhall SS, Pan JZ, Upadhyayula P, Manley GT, Bresnahan JC, Beattie MS, Ferguson AR, Talbott JF. PMID: 28007771.
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    83. Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015. Neurosurgery. 2016 Dec; 79(6):912-929. Collins MW, Kontos AP, Okonkwo DO, Almquist J, Bailes J, Barisa M, Bazarian J, Bloom OJ, Brody DL, Cantu R, Cardenas J, Clugston J, Cohen R, Echemendia R, Elbin RJ, Ellenbogen R, Fonseca J, Gioia G, Guskiewicz K, Heyer R, Hotz G, Iverson GL, Jordan B, Manley G, Maroon J, McAllister T, McCrea M, Mucha A, Pieroth E, Podell K, Pombo M, Shetty T, Sills A, Solomon G, Thomas DG, Valovich McLeod TC, Yates T, Zafonte R. PMID: 27741219.
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    84. DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury. Neurogenetics. 2017 01; 18(1):29-38. Yue JK, Winkler EA, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KK, Puccio AM, Mukherjee P, Diaz-Arrastia R, Gordon WA, Valadka AB, Okonkwo DO, Manley GT. PMID: 27826691.
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    85. Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 Nov; 79(5):708-714. Readdy WJ, Saigal R, Whetstone WD, Mefford AN, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. PMID: 27759678.
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    86. COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. J Clin Neurosci. 2017 Jan; 35:109-116. Winkler EA, Yue JK, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Tarapore PE, Burchard EG, Hu D, Eng C, Wang KK, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT. PMID: 27769642.
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    87. Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients. Neurobiol Sleep Circadian Rhythms. 2017 Jan; 2:85-93. Yue JK, Robinson CK, Winkler EA, Upadhyayula PS, Burke JF, Pirracchio R, Suen CG, Deng H, Ngwenya LB, Dhall SS, Manley GT, Tarapore PE. PMID: 31236497.
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    88. Advances in Neurotrauma Research. Neurosurg Clin N Am. 2016 Oct; 27(4):xv-xvi. Vespa PM, Hirt D, Manley GT. PMID: 27637404.
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    89. Cerebral Edema in Traumatic Brain Injury: Pathophysiology and Prospective Therapeutic Targets. Neurosurg Clin N Am. 2016 Oct; 27(4):473-88. Winkler EA, Minter D, Yue JK, Manley GT. PMID: 27637397.
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    90. Higher Mean Arterial Pressure Values Correlate with Neurologic Improvement in Patients with Initially Complete Spinal Cord Injuries. World Neurosurg. 2016 Dec; 96:72-79. Catapano JS, John Hawryluk GW, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. PMID: 27565460.
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    91. Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review. Respir Care. 2016 Sep; 61(9):1232-44. Ngwenya LB, Burke JF, Manley GT. PMID: 27435860.
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    92. Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries. Stat Methods Med Res. 2018 01; 27(1):286-297. Pirracchio R, Yue JK, Manley GT, van der Laan MJ, Hubbard AE. PMID: 27363429.
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    93. Developing a Cognition Endpoint for Traumatic Brain Injury Clinical Trials. J Neurotrauma. 2017 01 15; 34(2):363-371. Silverberg ND, Crane PK, Dams-O'Connor K, Holdnack J, Ivins BJ, Lange RT, Manley GT, McCrea M, Iverson GL. PMID: 27188248.
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    94. Screening for Post-Traumatic Stress Disorder in a Civilian Emergency Department Population with Traumatic Brain Injury. J Neurotrauma. 2017 01 01; 34(1):50-58. Haarbauer-Krupa J, Taylor CA, Yue JK, Winkler EA, Pirracchio R, Cooper SR, Burke JF, Stein MB, Manley GT. PMID: 26936513.
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    95. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg. 2016 06; 80(6):989-97. Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. PMID: 26881489.
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    96. Establishing a Traumatic Brain Injury Program of Care: Benchmarking Outcomes after Institutional Adoption of Evidence-Based Guidelines. J Neurotrauma. 2016 11 15; 33(22):2026-2033. Tarapore PE, Vassar MJ, Cooper S, Lay T, Galletly J, Manley GT, Huang MC. PMID: 26917004.
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    97. A novel antagonist of p75NTR reduces peripheral expansion and CNS trafficking of pro-inflammatory monocytes and spares function after traumatic brain injury. J Neuroinflammation. 2016 Apr 22; 13(1):88. Lee S, Mattingly A, Lin A, Sacramento J, Mannent L, Castel MN, Canolle B, Delbary-Gossart S, Ferzaz B, Morganti JM, Rosi S, Ferguson AR, Manley GT, Bresnahan JC, Beattie MS. PMID: 27102880.
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    98. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. Brain. 2016 06; 139(Pt 6):1762-82. Delbary-Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, Lin A, Sacramento J, Salegio EA, Castel MN, Delesque-Touchard N, Alam A, Laboudie P, Ferzaz B, Savi P, Herbert JM, Manley GT, Ferguson AR, Bresnahan JC, Bono F, Beattie MS. PMID: 27084575.
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    99. Adult sports-related traumatic brain injury in United States trauma centers. Neurosurg Focus. 2016 Apr; 40(4):E4. Winkler EA, Yue JK, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE. PMID: 27032921.
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    100. Pediatric sports-related traumatic brain injury in United States trauma centers. Neurosurg Focus. 2016 Apr; 40(4):E3. Yue JK, Winkler EA, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE. PMID: 27032920.
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    101. Brain tissue oxygen tension and its response to physiological manipulations: influence of distance from injury site in a swine model of traumatic brain injury. J Neurosurg. 2016 11; 125(5):1217-1228. Hawryluk GW, Phan N, Ferguson AR, Morabito D, Derugin N, Stewart CL, Knudson MM, Manley G, Rosenthal G. PMID: 26848909.
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    102. Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury. J Neurotrauma. 2016 05 15; 33(10):954-62. Mabray MC, Talbott JF, Whetstone WD, Dhall SS, Phillips DB, Pan JZ, Manley GT, Bresnahan JC, Beattie MS, Haefeli J, Ferguson AR. PMID: 26414451.
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    103. Plasma Anti-Glial Fibrillary Acidic Protein Autoantibody Levels during the Acute and Chronic Phases of Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study. J Neurotrauma. 2016 07 01; 33(13):1270-7. Wang KK, Yang Z, Yue JK, Zhang Z, Winkler EA, Puccio AM, Diaz-Arrastia R, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Manley GT, Cooper SR, Dams-O'Connor K, Hricik AJ, Inoue T, Maas AI, Menon DK, Schnyer DM, Sinha TK, Vassar MJ. PMID: 26560343.
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    104. COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury. Neurogenetics. 2016 Jan; 17(1):31-41. Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, Puccio AM, Wang KK, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT. PMID: 26576546.
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    105. Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury. Nat Commun. 2015 Oct 14; 6:8581. Nielson JL, Paquette J, Liu AW, Guandique CF, Tovar CA, Inoue T, Irvine KA, Gensel JC, Kloke J, Petrossian TC, Lum PY, Carlsson GE, Manley GT, Young W, Beattie MS, Bresnahan JC, Ferguson AR. PMID: 26466022.
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    106. Perioperative morbidity and mortality after lumbar trauma in the elderly. Neurosurg Focus. 2015 Oct; 39(4):E2. Winkler EA, Yue JK, Birk H, Robinson CK, Manley GT, Dhall SS, Tarapore PE. PMID: 26424342.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    107. A Review of the Effectiveness of Neuroimaging Modalities for the Detection of Traumatic Brain Injury. J Neurotrauma. 2015 Nov 15; 32(22):1693-721. Amyot F, Arciniegas DB, Brazaitis MP, Curley KC, Diaz-Arrastia R, Gandjbakhche A, Herscovitch P, Hinds SR, Manley GT, Pacifico A, Razumovsky A, Riley J, Salzer W, Shih R, Smirniotopoulos JG, Stocker D. PMID: 26176603.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    108. Circulating Brain-Derived Neurotrophic Factor Has Diagnostic and Prognostic Value in Traumatic Brain Injury. J Neurotrauma. 2016 Jan 15; 33(2):215-25. Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Lingsma HF, Puccio AM, Schnyer DM. PMID: 26159676.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    109. Mean Arterial Blood Pressure Correlates with Neurological Recovery after Human Spinal Cord Injury: Analysis of High Frequency Physiologic Data. J Neurotrauma. 2015 Dec 15; 32(24):1958-67. Hawryluk G, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. PMID: 25669633.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    110. Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome. J Neurosurg Spine. 2015 Nov; 23(5):574-580. Readdy WJ, Whetstone WD, Ferguson AR, Talbott JF, Inoue T, Saigal R, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Dhall SS. PMID: 26230417.
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    111. The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015 Oct; 23(4):495-504. Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. PMID: 26161519.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    112. Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury. J Neurotrauma. 2015 Oct 01; 32(19):1458-64. Yao X, Uchida K, Papadopoulos MC, Zador Z, Manley GT, Verkman AS. PMID: 25790314.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    113. Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice. Glia. 2015 Oct; 63(10):1860-9. Yao X, Smith AJ, Jin BJ, Zador Z, Manley GT, Verkman AS. PMID: 25944186.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    114. Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury. Neurogenetics. 2015 Jul; 16(3):169-80. Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT. PMID: 25633559.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    115. Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging. J Neurotrauma. 2015 Apr 15; 32(8):527-33. McMahon PJ, Panczykowski DM, Yue JK, Puccio AM, Inoue T, Sorani MD, Lingsma HF, Maas AI, Valadka AB, Yuh EL, Mukherjee P, Manley GT, Okonkwo DO. PMID: 25264814.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    116. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. Neurosurgery. 2015 Jan; 76(1):67-80. Maas AI, Menon DK, Steyerberg EW, Citerio G, Lecky F, Manley GT, Hill S, Legrand V, Sorgner A. PMID: 25525693.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    117. Genetic data sharing and privacy. Neuroinformatics. 2015 Jan; 13(1):1-6. Sorani MD, Yue JK, Sharma S, Manley GT, Ferguson AR. PMID: 25326433.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    118. Classification of traumatic brain injury: past, present, and future. Handb Clin Neurol. 2015; 127:15-21. Hawryluk GW, Manley GT. PMID: 25702207.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    119. Very early administration of progesterone for acute traumatic brain injury. N Engl J Med. 2014 Dec 25; 371(26):2457-66. Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS, Barsan WG. PMID: 25493974.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCTClinical Trials
    120. Outcome prediction after mild and complicated mild traumatic brain injury: external validation of existing models and identification of new predictors using the TRACK-TBI pilot study. J Neurotrauma. 2015 Jan 15; 32(2):83-94. Lingsma HF, Yue JK, Maas AI, Steyerberg EW, Manley GT. PMID: 25025611.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    121. Polyetheretherketone implants for the repair of large cranial defects: a 3-center experience. Neurosurgery. 2014 Nov; 75(5):523-9; discussion 528-9. Rosenthal G, Ng I, Moscovici S, Lee KK, Lay T, Martin C, Manley GT. PMID: 24979096.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    122. Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia. Neurosci Lett. 2015 Jan 01; 584:368-72. Yao X, Derugin N, Manley GT, Verkman AS. PMID: 25449874.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    123. Imaging concussion: a review. Neurosurgery. 2014 Oct; 75 Suppl 4:S50-63. Yuh EL, Hawryluk GW, Manley GT. PMID: 25232884.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    124. The Glasgow Coma Scale at 40 years: standing the test of time. Lancet Neurol. 2014 Aug; 13(8):844-54. Teasdale G, Maas A, Lecky F, Manley G, Stocchetti N, Murray G. PMID: 25030516.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    125. Diffusion tensor imaging for outcome prediction in mild traumatic brain injury: a TRACK-TBI study. J Neurotrauma. 2014 Sep 01; 31(17):1457-77. Yuh EL, Cooper SR, Mukherjee P, Yue JK, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Schnyer DM, Vassar MJ, Maas AI, Manley GT. PMID: 24742275.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    126. ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study. Am J Emerg Med. 2014 Aug; 32(8):844-50. Ratcliff JJ, Adeoye O, Lindsell CJ, Hart KW, Pancioli A, McMullan JT, Yue JK, Nishijima DK, Gordon WA, Valadka AB, Okonkwo DO, Lingsma HF, Maas AI, Manley GT. PMID: 24857248.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    127. The emergency department social work intervention for mild traumatic brain injury (SWIFT-Acute): a pilot study. Brain Inj. 2014; 28(4):448-55. Moore M, Winkelman A, Kwong S, Segal SP, Manley GT, Shumway M. PMID: 24702522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    128. Decompressive craniectomy for acute subdural hematomas. J Neurosurg. 2014 May; 120(5):1247-9; author reply 1249. Kolias AG, Hutchinson PJ, Menon DK, Manley GT, Gallagher CN, Servadei F. PMID: 24655100.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    129. Informatics for neurocritical care: challenges and opportunities. Neurocrit Care. 2014 Feb; 20(1):132-41. Sivaganesan A, Manley GT, Huang MC. PMID: 23884510.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    130. Medical and surgical management after spinal cord injury: vasopressor usage, early surgerys, and complications. J Neurotrauma. 2014 Feb 01; 31(3):284-91. Inoue T, Manley GT, Patel N, Whetstone WD. PMID: 24020382.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    131. Symptomatology and functional outcome in mild traumatic brain injury: results from the prospective TRACK-TBI study. J Neurotrauma. 2014 Jan 01; 31(1):26-33. McMahon P, Hricik A, Yue JK, Puccio AM, Inoue T, Lingsma HF, Beers SR, Gordon WA, Valadka AB, Manley GT, Okonkwo DO. PMID: 23952719.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    132. The impact of previous traumatic brain injury on health and functioning: a TRACK-TBI study. J Neurotrauma. 2013 Dec 15; 30(24):2014-20. Dams-O'Connor K, Spielman L, Singh A, Gordon WA, Lingsma HF, Maas AI, Manley GT, Mukherjee P, Okonkwo DO, Puccio AM, Schnyer DM, Valadka AB, Yue JK, Yuh EL. PMID: 23924069.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    133. Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein. J Neurotrauma. 2014 Jan 01; 31(1):19-25. Diaz-Arrastia R, Wang KK, Papa L, Sorani MD, Yue JK, Puccio AM, McMahon PJ, Inoue T, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Okonkwo DO, Manley GT. PMID: 23865516.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    134. Transforming research and clinical knowledge in traumatic brain injury pilot: multicenter implementation of the common data elements for traumatic brain injury. J Neurotrauma. 2013 Nov 15; 30(22):1831-44. Yue JK, Vassar MJ, Lingsma HF, Cooper SR, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Puccio AM, Schnyer DM, Manley GT. PMID: 23815563.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCTClinical Trials
    135. Progress in developing common data elements for traumatic brain injury research: version two--the end of the beginning. J Neurotrauma. 2013 Nov 15; 30(22):1852-61. Hicks R, Giacino J, Harrison-Felix C, Manley G, Valadka A, Wilde EA. PMID: 23725058.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    136. Traumatic brain injury: an international knowledge-based approach. JAMA. 2013 Aug 07; 310(5):473-4. Manley GT, Maas AI. PMID: 23925611.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    137. GFAP-BDP as an acute diagnostic marker in traumatic brain injury: results from the prospective transforming research and clinical knowledge in traumatic brain injury study. J Neurotrauma. 2013 Sep 01; 30(17):1490-7. Okonkwo DO, Yue JK, Puccio AM, Panczykowski DM, Inoue T, McMahon PJ, Sorani MD, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Manley GT. PMID: 23489259.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCTClinical Trials
    138. Military risk factors for Alzheimer's disease. Alzheimers Dement. 2013 Jul; 9(4):445-51. Weiner MW, Friedl KE, Pacifico A, Chapman JC, Jaffee MS, Little DM, Manley GT, McKee A, Petersen RC, Pitman RK, Yaffe K, Zetterberg H, Obana R, Bain LJ, Carrillo MC. PMID: 23809365.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    139. Combined SCI and TBI: recovery of forelimb function after unilateral cervical spinal cord injury (SCI) is retarded by contralateral traumatic brain injury (TBI), and ipsilateral TBI balances the effects of SCI on paw placement. Exp Neurol. 2013 Oct; 248:136-47. Inoue T, Lin A, Ma X, McKenna SL, Creasey GH, Manley GT, Ferguson AR, Bresnahan JC, Beattie MS. PMID: 23770071.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    140. Altering physiological networks using drugs: steps towards personalized physiology. BMC Med Genomics. 2013; 6 Suppl 2:S7. Grossman AD, Cohen MJ, Manley GT, Butte AJ. PMID: 23819503.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    141. Resting state magnetoencephalography functional connectivity in traumatic brain injury. J Neurosurg. 2013 Jun; 118(6):1306-16. Tarapore PE, Findlay AM, Lahue SC, Lee H, Honma SM, Mizuiri D, Luks TL, Manley GT, Nagarajan SS, Mukherjee P. PMID: 23600939.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    142. Summary of evidence-based guideline update: evaluation and management of concussion in sports: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2013 Jun 11; 80(24):2250-7. Giza CC, Kutcher JS, Ashwal S, Barth J, Getchius TS, Gioia GA, Gronseth GS, Guskiewicz K, Mandel S, Manley G, McKeag DB, Thurman DJ, Zafonte R. PMID: 23508730.
      View in: PubMed   Mentions: 165     Fields:    Translation:Humans
    143. Mosaic evolution of the mammalian auditory periphery. Adv Exp Med Biol. 2013; 787:3-9. Manley GA. PMID: 23716203.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    144. Magnetic resonance imaging improves 3-month outcome prediction in mild traumatic brain injury. Ann Neurol. 2013 Feb; 73(2):224-35. Yuh EL, Mukherjee P, Lingsma HF, Yue JK, Ferguson AR, Gordon WA, Valadka AB, Schnyer DM, Okonkwo DO, Maas AI, Manley GT. PMID: 23224915.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    145. Early management of severe traumatic brain injury. Lancet. 2012 Sep 22; 380(9847):1088-98. Rosenfeld JV, Maas AI, Bragge P, Morganti-Kossmann MC, Manley GT, Gruen RL. PMID: 22998718.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    146. A longitudinal MRI study of traumatic axonal injury in patients with moderate and severe traumatic brain injury. J Neurol Neurosurg Psychiatry. 2012 Dec; 83(12):1193-200. Moen KG, Skandsen T, Folvik M, Brezova V, Kvistad KA, Rydland J, Manley GT, Vik A. PMID: 22933813.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    147. Coagulopathy after traumatic brain injury. Neurosurgery. 2012 Jun; 70(6):1334-45. Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT. PMID: 22307074.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    148. Quantitative CT improves outcome prediction in acute traumatic brain injury. J Neurotrauma. 2012 Mar 20; 29(5):735-46. Yuh EL, Cooper SR, Ferguson AR, Manley GT. PMID: 21970562.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    149. Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice. J Neurotrauma. 2011 09 22. Lu DC, Zador Z, Yao J, Fazlollahi F, Manley GT. PMID: 21939392.
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    150. Re-orientation of clinical research in traumatic brain injury: report of an international workshop on comparative effectiveness research. J Neurotrauma. 2012 Jan 01; 29(1):32-46. Maas AI, Menon DK, Lingsma HF, Pineda JA, Sandel ME, Manley GT. PMID: 21545277.
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    151. The effect of decompressive hemicraniectomy on brain temperature after severe brain injury. Neurocrit Care. 2011 Aug; 15(1):101-6. Nakagawa K, Hills NK, Kamel H, Patel PV, Manley GT, Hemphill JC. PMID: 21061187.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    152. Marked reduction in wound complication rates following decompressive hemicraniectomy with an improved operative closure technique. J Clin Neurosci. 2011 Sep; 18(9):1201-5. Sughrue ME, Bloch OG, Manley GT, Stiver SI. PMID: 21752652.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    153. Temporizing treatment of hyperacute subdural hemorrhage by subdural evacuation port system placement. J Neurosurg. 2011 Oct; 115(4):844-8. Flint AC, Gean AD, Manley GT, Rao VA, Sheridan WF, von Koch CS. PMID: 21682569.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    154. Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research. J Neurotrauma. 2011 Jun; 28(6):1101-19. Nakagawa A, Manley GT, Gean AD, Ohtani K, Armonda R, Tsukamoto A, Yamamoto H, Takayama K, Tominaga T. PMID: 21332411.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    155. Tight squeeze, slow burn: inflammation and the aetiology of cervical myelopathy. Brain. 2011 May; 134(Pt 5):1259-61. Beattie MS, Manley GT. PMID: 21596766.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    156. Dynamic, multi-level network models of clinical trials. Pac Symp Biocomput. 2011; 38-49. Sorani MD, Manley GT, Claude Hemphill J, Baranzini SE. PMID: 21121031.
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    157. [Neuromonitoring and neurocritical care for severe TBI: current update]. No Shinkei Geka. 2010 Dec; 38(12):1081-95. Nakagawa A, Manley G, Tominaga T. PMID: 21160100.
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    158. NIH Roundtable on Emergency Trauma Research. Ann Emerg Med. 2010 Nov; 56(5):538-50. Cairns CB, Maier RV, Adeoye O, Baptiste D, Barsan WG, Blackbourne L, Burd R, Carpenter C, Chang D, Cioffi W, Cornwell E, Dean JM, Dyer C, Jaffe D, Manley G, Meurer WJ, Neumar R, Silbergleit R, Stevens M, Wang M, Weiner D, Wright D. PMID: 21036294.
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    159. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Arch Phys Med Rehabil. 2010 Nov; 91(11):1667-72. Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. PMID: 21044710.
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    160. Common data elements for research on traumatic brain injury and psychological health: current status and future development. Arch Phys Med Rehabil. 2010 Nov; 91(11):1692-6. Whyte J, Vasterling J, Manley GT. PMID: 21044713.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    161. Hemicraniectomy: a new model for human electrophysiology with high spatio-temporal resolution. J Cogn Neurosci. 2010 Nov; 22(11):2491-502. Voytek B, Secundo L, Bidet-Caulet A, Scabini D, Stiver SI, Gean AD, Manley GT, Knight RT. PMID: 19925193.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    162. Abrupt increase in rat carotid blood flow induces rapid alteration of artery mechanical properties. J Mech Behav Biomed Mater. 2011 Jan; 4(1):9-15. Monson KL, Matsumoto MM, Young WL, Manley GT, Hashimoto T. PMID: 21094476.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    163. Benign anterior temporal epidural hematoma: indolent lesion with a characteristic CT imaging appearance after blunt head trauma. Radiology. 2010 Oct; 257(1):212-8. Gean AD, Fischbein NJ, Purcell DD, Aiken AH, Manley GT, Stiver SI. PMID: 20713606.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    164. Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury. J Neurosurg. 2011 Jan; 114(1):62-70. Rosenthal G, Sanchez-Mejia RO, Phan N, Hemphill JC, Martin C, Manley GT. PMID: 20707619.
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    165. Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis. Crit Care. 2010; 14(1):R10. Cohen MJ, Grossman AD, Morabito D, Knudson MM, Butte AJ, Manley GT. PMID: 20122274.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    166. Interobserver variability in the assessment of CT imaging features of traumatic brain injury. J Neurotrauma. 2010 Feb; 27(2):325-30. Chun KA, Manley GT, Stiver SI, Aiken AH, Phan N, Wang V, Meeker M, Cheng SC, Gean AD, Wintermark M. PMID: 19895192.
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    167. Clinical trials in traumatic brain injury: past experience and current developments. Neurotherapeutics. 2010 Jan; 7(1):115-26. Maas AI, Roozenbeek B, Manley GT. PMID: 20129503.
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    168. Infection in the intensive care unit alters physiological networks. BMC Bioinformatics. 2009 Sep 17; 10 Suppl 9:S4. Grossman AD, Cohen MJ, Manley GT, Butte AJ. PMID: 19761574.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    169. Rib head disarticulation for multilevel transpedicular thoracic corpectomies and expandable cage reconstruction. Neurol India. 2009 Jul-Aug; 57(4):469-74. Chou D, Eltgroth M, Yang I, Lu D, Manley G. PMID: 19770550.
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    170. Race\ethnicity and outcome after traumatic brain injury at a single, diverse center. J Trauma. 2009 Jul; 67(1):75-80. Sorani MD, Lee M, Kim H, Meeker M, Manley GT. PMID: 19590312.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    171. Introduction: decompressive craniectomy for trauma and cerebrovascular disease. Neurosurg Focus. 2009 Jun; 26(6):E1. Manley GT. PMID: 19485713.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    172. Survival with good outcome after cerebral herniation and Duret hemorrhage caused by traumatic brain injury. J Neurosurg. 2009 Jun; 110(6):1242-6. Stiver SI, Gean AD, Manley GT. PMID: 19012479.
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    173. Effects of white, grey, and pia mater properties on tissue level stresses and strains in the compressed spinal cord. J Neurotrauma. 2009 Apr; 26(4):585-95. Sparrey CJ, Manley GT, Keaveny TM. PMID: 19292657.
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    174. Refining resuscitation strategies using tissue oxygen and perfusion monitoring in critical organ beds. J Trauma. 2009 Feb; 66(2):353-7. Wan JJ, Cohen MJ, Rosenthal G, Haitsma IK, Morabito DJ, Derugin N, Knudson MM, Manley GT. PMID: 19204507.
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    175. Role of aquaporin-4 in cerebral edema and stroke. Handb Exp Pharmacol. 2009; (190):159-70. Zador Z, Stiver S, Wang V, Manley GT. PMID: 19096776.
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    176. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2009 Jan; 37(1):379-380. Rosenthal G, Hemphill JC, Manley G. PMID: 19318818.
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    177. The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury. Neurosurgery. 2008 Dec; 63(6):1159-64; discussion 1164-5. Stewart C, Haitsma I, Zador Z, Hemphill JC, Morabito D, Manley G, Rosenthal G. PMID: 19057329.
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    178. Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury. Brain. 2008 Dec; 131(Pt 12):3209-21. Niogi SN, Mukherjee P, Ghajar J, Johnson CE, Kolster R, Lee H, Suh M, Zimmerman RD, Manley GT, McCandliss BD. PMID: 18952679.
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    179. Biaxial response of passive human cerebral arteries. Ann Biomed Eng. 2008 Dec; 36(12):2028-41. Monson KL, Barbaro NM, Manley GT. PMID: 18855141.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    180. Computer-aided assessment of head computed tomography (CT) studies in patients with suspected traumatic brain injury. J Neurotrauma. 2008 Oct; 25(10):1163-72. Yuh EL, Gean AD, Manley GT, Callen AL, Wintermark M. PMID: 18986221.
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    181. Relationship of "dose" of intracranial hypertension to outcome in severe traumatic brain injury. J Neurosurg. 2008 Oct; 109(4):678-84. Vik A, Nag T, Fredriksli OA, Skandsen T, Moen KG, Schirmer-Mikalsen K, Manley GT. PMID: 18826355.
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    182. Prehospital management of traumatic brain injury. Neurosurg Focus. 2008 Oct; 25(4):E5. Stiver SI, Manley GT. PMID: 18828703.
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    183. Genetic variation in human aquaporins and effects on phenotypes of water homeostasis. Hum Mutat. 2008 Sep; 29(9):1108-17. Sorani MD, Manley GT, Giacomini KM. PMID: 18470935.
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    184. Focal lesions in acute mild traumatic brain injury and neurocognitive outcome: CT versus 3T MRI. J Neurotrauma. 2008 Sep; 25(9):1049-56. Lee H, Wintermark M, Gean AD, Ghajar J, Manley GT, Mukherjee P. PMID: 18707244.
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    185. Reversible monoparesis following decompressive hemicraniectomy for traumatic brain injury. J Neurosurg. 2008 Aug; 109(2):245-54. Stiver SI, Wintermark M, Manley GT. PMID: 18671636.
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    186. Classification of traumatic brain injury for targeted therapies. J Neurotrauma. 2008 Jul; 25(7):719-38. Saatman KE, Duhaime AC, Bullock R, Maas AI, Valadka A, Manley GT. PMID: 18627252.
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    187. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008 Jun; 36(6):1917-24. Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT. PMID: 18496376.
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    188. Novel variants in human Aquaporin-4 reduce cellular water permeability. Hum Mol Genet. 2008 Aug 01; 17(15):2379-89. Sorani MD, Zador Z, Hurowitz E, Yan D, Giacomini KM, Manley GT. PMID: 18511455.
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    189. Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci. 2008 May 21; 28(21):5460-4. Yao X, Hrabetová S, Nicholson C, Manley GT. PMID: 18495879.
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    190. Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury. J Neurotrauma. 2008 May; 25(5):503-12. Flint AC, Manley GT, Gean AD, Hemphill JC, Rosenthal G. PMID: 18346002.
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    191. Characterizing the dose-response relationship between mannitol and intracranial pressure in traumatic brain injury patients using a high-frequency physiological data collection system. J Neurotrauma. 2008 Apr; 25(4):291-8. Sorani MD, Morabito D, Rosenthal G, Giacomini KM, Manley GT. PMID: 18373479.
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    192. Cerebral salt wasting and elevated brain natriuretic peptide levels after traumatic brain injury: 2 case reports. Surg Neurol. 2008 Mar; 69(3):226-9. Lu DC, Binder DK, Chien B, Maisel A, Manley GT. PMID: 18325424.
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    193. Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation. J Neurosurg. 2008 Mar; 108(3):575-87. Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, Knudson MM, Manley G. PMID: 18312106.
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    194. Extent of microstructural white matter injury in postconcussive syndrome correlates with impaired cognitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain injury. AJNR Am J Neuroradiol. 2008 May; 29(5):967-73. Niogi SN, Mukherjee P, Ghajar J, Johnson C, Kolster RA, Sarkar R, Lee H, Meeker M, Zimmerman RD, Manley GT, McCandliss BD. PMID: 18272556.
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    195. Recognition of paroxysmal autonomic instability with dystonia (PAID) in a patient with traumatic brain injury. J Trauma. 2008 Feb; 64(2):500-2. Wang VY, Manley G. PMID: 18301221.
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    196. Predictive values of age and the Glasgow Coma Scale in traumatic brain injury patients treated with decompressive craniectomy. Acta Neurochir Suppl. 2008; 102:109-12. Potts MB, Chi JH, Meeker M, Holland MC, Claude HJ, Manley GT. PMID: 19388299.
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    197. In vitro comparison of two generations of Licox and Neurotrend catheters. Acta Neurochir Suppl. 2008; 102:197-202. Haitsma I, Rosenthal G, Morabito D, Rollins M, Maas AI, Manley GT. PMID: 19388316.
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    198. The role of lung function in brain tissue oxygenation following traumatic brain injury. J Neurosurg. 2008 Jan; 108(1):59-65. Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Meeker M, Wang V, Manley GT. PMID: 18173311.
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    199. Dose-response relationship of mannitol and intracranial pressure: a metaanalysis. J Neurosurg. 2008 Jan; 108(1):80-7. Sorani MD, Manley GT. PMID: 18173314.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    200. Motor trephine syndrome: a mechanistic hypothesis. Acta Neurochir Suppl. 2008; 102:273-7. Stiver SI, Wintermark M, Manley GT. PMID: 19388328.
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    201. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma. 2007 Dec; 63(6):1254-61; discussion 1261-2. Cohen MJ, Brohi K, Ganter MT, Manley GT, Mackersie RC, Pittet JF. PMID: 18212647.
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    202. Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain. FASEB J. 2008 Mar; 22(3):870-9. Zador Z, Magzoub M, Jin S, Manley GT, Papadopoulos MC, Verkman AS. PMID: 17965267.
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    203. The role of early follow-up computed tomography imaging in the management of traumatic brain injury patients with intracranial hemorrhage. J Trauma. 2007 Jul; 63(1):75-82. Smith JS, Chang EF, Rosenthal G, Meeker M, von Koch C, Manley GT, Holland MC. PMID: 17622872.
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    204. Emergent placement of halo orthosis after a traumatic cervical injury leading to a cerebral abscess. J Trauma. 2007 Jun; 62(6):E11-3. Quiñones-Hinojosa A, Chi JH, Manley GT. PMID: 17563638.
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    205. The role of aquaporin-4 in cerebral water transport and edema. Neurosurg Focus. 2007 May 15; 22(5):E3. Bloch O, Manley GT. PMID: 17613234.
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    206. Aquaporins: role in cerebral edema and brain water balance. Prog Brain Res. 2007; 161:185-94. Zador Z, Bloch O, Yao X, Manley GT. PMID: 17618977.
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    207. New approaches to physiological informatics in neurocritical care. Neurocrit Care. 2007; 7(1):45-52. Sorani MD, Hemphill JC, Morabito D, Rosenthal G, Manley GT. PMID: 17565451.
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    208. Guidelines for the management of severe traumatic brain injury. II. Hyperosmolar therapy. J Neurotrauma. 2007; 24 Suppl 1:S14-20. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511539.
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    209. Guidelines for the management of severe traumatic brain injury. VII. Intracranial pressure monitoring technology. J Neurotrauma. 2007; 24 Suppl 1:S45-54. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511545.
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    210. Guidelines for the management of severe traumatic brain injury. VIII. Intracranial pressure thresholds. J Neurotrauma. 2007; 24 Suppl 1:S55-8. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511546.
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    211. Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds. J Neurotrauma. 2007; 24 Suppl 1:S59-64. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511547.
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    212. Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds. J Neurotrauma. 2007; 24 Suppl 1:S65-70. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511548.
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    213. Guidelines for the management of severe traumatic brain injury. I. Blood pressure and oxygenation. J Neurotrauma. 2007; 24 Suppl 1:S7-13. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511549.
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    214. Guidelines for the management of severe traumatic brain injury. XII. Nutrition. J Neurotrauma. 2007; 24 Suppl 1:S77-82. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511551.
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    215. Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis. J Neurotrauma. 2007; 24 Suppl 1:S83-6. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511552.
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    216. Guidelines for the management of severe traumatic brain injury. XIV. Hyperventilation. J Neurotrauma. 2007; 24 Suppl 1:S87-90. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511553.
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    217. Guidelines for the management of severe traumatic brain injury. III. Prophylactic hypothermia. J Neurotrauma. 2007; 24 Suppl 1:S21-5. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511540.
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    218. Guidelines for the management of severe traumatic brain injury. IV. Infection prophylaxis. J Neurotrauma. 2007; 24 Suppl 1:S26-31. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511541.
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    219. Guidelines for the management of severe traumatic brain injury. V. Deep vein thrombosis prophylaxis. J Neurotrauma. 2007; 24 Suppl 1:S32-6. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511543.
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    220. Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma. 2007; 24 Suppl 1:S37-44. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511544.
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    221. Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives. J Neurotrauma. 2007; 24 Suppl 1:S71-6. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511550.
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    222. Guidelines for the management of severe traumatic brain injury. XV. Steroids. J Neurotrauma. 2007; 24 Suppl 1:S91-5. Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. PMID: 17511554.
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    223. Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J. 2007 Jan; 21(1):108-16. Auguste KI, Jin S, Uchida K, Yan D, Manley GT, Papadopoulos MC, Verkman AS. PMID: 17135365.
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    224. Prehospital hypoxia affects outcome in patients with traumatic brain injury: a prospective multicenter study. J Trauma. 2006 Nov; 61(5):1134-41. Chi JH, Knudson MM, Vassar MJ, McCarthy MC, Shapiro MB, Mallet S, Holcroft JJ, Moncrief H, Noble J, Wisner D, Kaups KL, Bennick LD, Manley GT. PMID: 17099519.
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    225. Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study. J Trauma. 2006 Oct; 61(4):780-8; discussion 788-90. Ikossi DG, Knudson MM, Morabito DJ, Cohen MJ, Wan JJ, Khaw L, Stewart CJ, Hemphill C, Manley GT. PMID: 17033541.
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    226. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia. 2006 Apr 15; 53(6):631-6. Binder DK, Yao X, Zador Z, Sick TJ, Verkman AS, Manley GT. PMID: 16470808.
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    227. Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice. J Cereb Blood Flow Metab. 2006 Dec; 26(12):1527-37. Bloch O, Auguste KI, Manley GT, Verkman AS. PMID: 16552421.
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    228. Controlled cortical impact in swine: pathophysiology and biomechanics. J Neurotrauma. 2006 Feb; 23(2):128-39. Manley GT, Rosenthal G, Lam M, Morabito D, Yan D, Derugin N, Bollen A, Knudson MM, Panter SS. PMID: 16503797.
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    229. Impaired pain sensation in mice lacking Aquaporin-1 water channels. Biochem Biophys Res Commun. 2006 Mar 24; 341(4):1022-8. Oshio K, Watanabe H, Yan D, Verkman AS, Manley GT. PMID: 16476579.
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    230. Increased seizure duration in mice lacking aquaporin-4 water channels. Acta Neurochir Suppl. 2006; 96:389-92. Binder DK, Yao X, Verkman AS, Manley GT. PMID: 16671491.
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    231. Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial. J Trauma. 2005 Dec; 59(6):1298-304; discussion 1304. Livingston DH, Lavery RF, Mosenthal AC, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R. PMID: 16394900.
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    232. Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci. 2005 Dec 15; 118(Pt 24):5691-8. Saadoun S, Papadopoulos MC, Watanabe H, Yan D, Manley GT, Verkman AS. PMID: 16303850.
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    233. K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods. 2005 Nov; 2(11):825-7. Padmawar P, Yao X, Bloch O, Manley GT, Verkman AS. PMID: 16278651.
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    234. Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study. Neurosurgery. 2005 Oct; 57(4):727-36; discussion 727-36. Ware ML, Nemani VM, Meeker M, Lee C, Morabito DJ, Manley GT. PMID: 16239885.
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    235. Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. J Neurochem. 2005 Oct; 95(1):254-62. Bloch O, Papadopoulos MC, Manley GT, Verkman AS. PMID: 16181429.
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    236. Pregnancy-related vertebral hemangioma. Case report, review of the literature, and management algorithm. Neurosurg Focus. 2005 Sep 15; 19(3):E7. Chi JH, Manley GT, Chou D. PMID: 16190606.
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    237. Airbag deployment and improperly restrained children: a lethal combination. J Trauma. 2005 Sep; 59(3):729-33. Quiñones-Hinojosa A, Jun P, Manley GT, Knudson MM, Gupta N. PMID: 16361920.
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    238. Evaluation of the portable infrared pupillometer. Neurosurgery. 2005 Jul; 57(1):198-203; discussion 198-203. Du R, Meeker M, Bacchetti P, Larson MD, Holland MC, Manley GT. PMID: 15987563.
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    239. Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results. AJNR Am J Neuroradiol. 2005 May; 26(5):1095-100. Hemphill JC, Smith WS, Sonne DC, Morabito D, Manley GT. PMID: 15891166.
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    240. Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care. Physiol Meas. 2005 Aug; 26(4):373-86. Hemphill JC, Barton CW, Morabito D, Manley GT. PMID: 15886433.
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    241. Significance of source and size in the mechanical response of human cerebral blood vessels. J Biomech. 2005 Apr; 38(4):737-44. Monson KL, Goldsmith W, Barbaro NM, Manley GT. PMID: 15713294.
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    242. Pupil examination: validity and clinical utility of an automated pupillometer. J Neurosci Nurs. 2005 Feb; 37(1):34-40. Meeker M, Du R, Bacchetti P, Privitera CM, Larson MD, Holland MC, Manley G. PMID: 15794443.
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    243. Expression of the aquaporin-1 water channel in human glial tumors. Neurosurgery. 2005 Feb; 56(2):375-81; discussion 375-81. Oshio K, Binder DK, Liang Y, Bollen A, Feuerstein B, Berger MS, Manley GT. PMID: 15670385.
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    244. Brain tissue oxygen monitoring in intracerebral hemorrhage. Neurocrit Care. 2005; 3(3):260-70. Hemphill JC, Morabito D, Farrant M, Manley GT. PMID: 16377842.
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    245. A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients. Acad Emerg Med. 2005 Jan; 12(1):1-6. Barton CW, Hemphill JC, Morabito D, Manley G. PMID: 15635130.
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    246. Diffusion tensor imaging with three-dimensional fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal "disconnection" syndrome: case report. Neurosurgery. 2005; 56(1):189. Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT. PMID: 15617604.
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    247. Diffusion Tensor Imaging with Three-dimensional Fiber Tractography of Traumatic Axonal Shearing Injury: An Imaging Correlate for the Posterior Callosal "Disconnection" Syndrome: Case Report. Neurosurgery. 2005 Jan 01; 56(1):E195-E201. Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT. PMID: 28184703.
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    248. Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J. 2005 Jan; 19(1):76-8. Oshio K, Watanabe H, Song Y, Verkman AS, Manley GT. PMID: 15533949.
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    249. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J. 2004 Aug; 18(11):1291-3. Papadopoulos MC, Manley GT, Krishna S, Verkman AS. PMID: 15208268.
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    250. The effect of age on functional outcome in mild traumatic brain injury: 6-month report of a prospective multicenter trial. J Trauma. 2004 May; 56(5):1042-8. Mosenthal AC, Livingston DH, Lavery RF, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R. PMID: 15179244.
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    251. Volumetric proton spectroscopic imaging of mild traumatic brain injury. AJNR Am J Neuroradiol. 2004 May; 25(5):730-7. Govindaraju V, Gauger GE, Manley GT, Ebel A, Meeker M, Maudsley AA. PMID: 15140711.
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    252. Transcranial motor evoked potential recording in a case of Kernohan's notch syndrome: case report. Neurosurgery. 2004 Apr; 54(4):999-1002; discussion 1002-3. Binder DK, Lyon R, Manley GT. PMID: 15046669.
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    253. Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport. 2004 Feb 09; 15(2):259-62. Binder DK, Oshio K, Ma T, Verkman AS, Manley GT. PMID: 15076748.
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    254. Expression of aquaporin water channels in mouse spinal cord. Neuroscience. 2004; 127(3):685-93. Oshio K, Binder DK, Yang B, Schecter S, Verkman AS, Manley GT. PMID: 15283967.
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    255. New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience. 2004; 129(4):983-91. Manley GT, Binder DK, Papadopoulos MC, Verkman AS. PMID: 15561413.
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    256. Diagnosis of posttraumatic transverse sinus thrombosis with magnetic resonance imaging/magnetic resonance venography: report of two cases. J Trauma. 2004 Jan; 56(1):201-4. Quiñones-Hinojosa A, Binder DK, Hemphill JC, Manley GT. PMID: 14749592.
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    257. Molecular mechanisms of brain tumor edema. Neuroscience. 2004; 129(4):1011-20. Papadopoulos MC, Saadoun S, Binder DK, Manley GT, Krishna S, Verkman AS. PMID: 15561416.
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    258. Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C426-32. Solenov E, Watanabe H, Manley GT, Verkman AS. PMID: 14576087.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    259. Axial mechanical properties of fresh human cerebral blood vessels. J Biomech Eng. 2003 Apr; 125(2):288-94. Monson KL, Goldsmith W, Barbaro NM, Manley GT. PMID: 12751292.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    260. Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201. J Trauma. 2003 Feb; 54(2):242-52. Knudson MM, Lee S, Erickson V, Morabito D, Derugin N, Manley GT. PMID: 12579047.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    261. Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation. Adv Exp Med Biol. 2003; 530:311-7. Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM. PMID: 14562727.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    262. Aquaporin-1 expression in human glial tumors suggests a potential novel therapeutic target for tumor-associated edema. Acta Neurochir Suppl. 2003; 86:499-502. Oshio K, Binder DK, Bollen A, Verkman AS, Berger MS, Manley GT. PMID: 14753494.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    263. Aquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production. Acta Neurochir Suppl. 2003; 86:525-8. Oshio K, Song Y, Verkman AS, Manley GT. PMID: 14753499.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    264. Computational study of the contribution of the vasculature on the dynamic response of the brain. Stapp Car Crash J. 2002 Nov; 46:145-64. Zhang L, Bae J, Hardy WN, Monson KL, Manley GT, Goldsmith W, Yang KH, King AI. PMID: 17096223.
      View in: PubMed   Mentions: 9     Fields:    
    265. Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine. Acad Emerg Med. 2002 Oct; 9(10):969-76. Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT. PMID: 12359531.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    266. Infrared pupillometry during uncal herniation. J Neurosurg Anesthesiol. 2002 Jul; 14(3):223-8. Manley GT, Larson MD. PMID: 12172296.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    267. Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice. J Neurosci Methods. 2002 Jan 15; 113(1):85-90. Solenov EI, Vetrivel L, Oshio K, Manley GT, Verkman AS. PMID: 11741725.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    268. Hypotension, hypoxia, and head injury: frequency, duration, and consequences. Arch Surg. 2001 Oct; 136(10):1118-23. Manley G, Knudson MM, Morabito D, Damron S, Erickson V, Pitts L. PMID: 11585502.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    269. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001 Apr; 32(4):891-7. Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC. PMID: 11283388.
      View in: PubMed   Mentions: 350     Fields:    Translation:Humans
    270. Carbon dioxide reactivity and pressure autoregulation of brain tissue oxygen. Neurosurgery. 2001 Feb; 48(2):377-83; discussion 383-4. Hemphill JC, Knudson MM, Derugin N, Morabito D, Manley GT. PMID: 11220382.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    271. Cerebral oxygenation during hemorrhagic shock: perils of hyperventilation and the therapeutic potential of hypoventilation. J Trauma. 2000 Jun; 48(6):1025-32; discussion 1032-3. Manley GT, Hemphill JC, Morabito D, Derugin N, Erickson V, Pitts LH, Knudson MM. PMID: 10866246.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    272. Skeletal muscle function and water permeability in aquaporin-4 deficient mice. Am J Physiol Cell Physiol. 2000 Jun; 278(6):C1108-15. Yang B, Verbavatz JM, Song Y, Vetrivel L, Manley G, Kao WM, Ma T, Verkman AS. PMID: 10837338.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    273. Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice. Exp Physiol. 2000 Mar; 85 Spec No:233S-241S. Verkman AS, Yang B, Song Y, Manley GT, Ma T. PMID: 10795927.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    274. Acute posterior fossa syndrome following lumbar drainage for treatment of suboccipital pseudomeningocele. Report of three cases. J Neurosurg. 2000 Mar; 92(3):469-74. Manley GT, Dillon W. PMID: 10701537.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    275. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med. 2000 Feb; 6(2):159-63. Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman AS. PMID: 10655103.
      View in: PubMed   Mentions: 369     Fields:    Translation:Animals
    276. Brain tissue oxygenation during hemorrhagic shock, resuscitation, and alterations in ventilation. J Trauma. 1999 Feb; 46(2):261-7. Manley GT, Pitts LH, Morabito D, Doyle CA, Gibson J, Gimbel M, Hopf HW, Knudson MM. PMID: 10029031.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    277. Detection of Bartonella henselae by polymerase chain reaction in brain tissue of an immunocompromised patient with multiple enhancing lesions. Case report and review of the literature. J Neurosurg. 1998 Oct; 89(4):640-4. George TI, Manley G, Koehler JE, Hung VS, McDermott M, Bollen A. PMID: 9761060.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    278. Inhibition of proliferation and induction of differentiation in medulloblastoma- and astrocytoma-derived cell lines with phenylacetate. J Neurosurg. 1995 Oct; 83(4):672-81. Stockhammer G, Manley GT, Johnson R, Rosenblum MK, Samid D, Lieberman FS. PMID: 7674018.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    279. Measurement of heparan sulphate in normal human serum by laser nephelometry. Clin Chim Acta. 1984 Mar 13; 137(3):355-9. Warren C, Manley G. PMID: 6230179.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    280. Excretion patterns of glycosaminoglycans and glycoproteins in normal human urine. J Clin Pathol. 1968 May; 21(3):339-45. Manley G, Severn M, Hawksworth J. PMID: 4235293.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
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