Geoffrey O'Donoghue, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentCellular Molecular Pharmacology
Address600 16th Street
San Francisco CA 94158
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    1. Pielak RM, O'Donoghue G, Lin JJ, Alfieri KN, Fay NC, Low-Nam ST, Groves JT. Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Proc Natl Acad Sci U S A. 2017 Nov 14; 114(46):12190-12195. PMID: 29087297.
      View in: PubMed
    2. Bugaj LJ, O'Donoghue G, Lim WA. Interrogating cellular perception and decision making with optogenetic tools. J Cell Biol. 2017 Jan 02; 216(1):25-28. PMID: 28003330.
      View in: PubMed
    3. Caculitan NG, Kai H, Liu EY, Fay N, Yu Y, Lohm├╝ller T, O'Donoghue G, Groves JT. Size-based chromatography of signaling clusters in a living cell membrane. Nano Lett. 2014 May 14; 14(5):2293-8. PMID: 24655064; PMCID: PMC4025576.
    4. O'Donoghue G, Pielak RM, Smoligovets AA, Lin JJ, Groves JT. Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells. Elife. 2013 Jul 03; 2:e00778. PMID: 23840928; PMCID: PMC3701909.
    5. Lau C, Mirkovic J, Yu CC, O'Donoghue G, Galindo L, Dasari R, de las Morenas A, Feld M, Stier E. Early detection of high-grade squamous intraepithelial lesions in the cervix with quantitative spectroscopic imaging. J Biomed Opt. 2013 Jul; 18(7):76013. PMID: 23843090; PMCID: PMC3706901.
    6. Belardi B, O'Donoghue G, Smith AW, Groves JT, Bertozzi CR. Investigating cell surface galectin-mediated cross-linking on glycoengineered cells. J Am Chem Soc. 2012 Jun 13; 134(23):9549-52. PMID: 22540968; PMCID: PMC3374418.
    7. Lohm├╝ller T, Triffo S, O'Donoghue G, Xu Q, Coyle MP, Groves JT. Supported membranes embedded with fixed arrays of gold nanoparticles. Nano Lett. 2011 Nov 09; 11(11):4912-8. PMID: 21967595; PMCID: PMC3212849.
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