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Giang Le, MD

TitleFellow
SchoolUCSF School of Medicine
DepartmentAnesthesia
Address513 Parnassus Avenue
San Francisco CA 94117
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hoang HN, Driver RW, Beyer RL, Malde AK, Le G, Abbenante G, Mark AE, Fairlie DP. Protein a-turns recreated in structurally stable small molecules. Angew Chem Int Ed Engl. 2011 Nov 18; 50(47):11107-11. PMID: 21956852.
      View in: PubMed
    2. Wielens J, Headey SJ, Deadman JJ, Rhodes DI, Le G, Parker MW, Chalmers DK, Scanlon MJ. Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1. ChemMedChem. 2011 Feb 07; 6(2):258-61. PMID: 21275048.
      View in: PubMed
    3. Barry GD, Suen JY, Le G, Cotterell A, Reid RC, Fairlie DP. Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28; 53(20):7428-40. PMID: 20873792.
      View in: PubMed
    4. Löser R, Abbenante G, Madala PK, Halili M, Le G, Fairlie DP. Noncovalent tripeptidyl benzyl- and cyclohexyl-amine inhibitors of the cysteine protease caspase-1. J Med Chem. 2010 Mar 25; 53(6):2651-5. PMID: 20170165.
      View in: PubMed
    5. Halili MA, Andrews MR, Labzin LI, Schroder K, Matthias G, Cao C, Lovelace E, Reid RC, Le G, Hume DA, Irvine KM, Matthias P, Fairlie DP, Sweet MJ. Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. J Leukoc Biol. 2010 Jun; 87(6):1103-14. PMID: 20200406.
      View in: PubMed
    6. Iyer A, Fenning A, Lim J, Le G, Reid RC, Halili MA, Fairlie DP, Brown L. Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. Br J Pharmacol. 2010 Apr; 159(7):1408-17. PMID: 20180942; PMCID: PMC2850398.
    7. Ruiz-Gómez G, Lim J, Halili MA, Le G, Madala PK, Abbenante G, Fairlie DP. Structure-activity relationships for substrate-based inhibitors of human complement factor B. J Med Chem. 2009 Oct 08; 52(19):6042-52. PMID: 19743866.
      View in: PubMed
    8. Halili MA, Ruiz-Gómez G, Le G, Abbenante G, Fairlie DP. Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. Biochemistry. 2009 Sep 08; 48(35):8466-72. PMID: 19642650.
      View in: PubMed
    9. Le G, Abbenante G, Fairlie DP. Profiling the enzymatic properties and inhibition of human complement factor B. J Biol Chem. 2007 Nov 30; 282(48):34809-16. PMID: 17921140.
      View in: PubMed
    10. Abbenante G, Le G, Fairlie DP. Unexpected photolytic decomposition of alkyl azides under mild conditions. Chem Commun (Camb). 2007 Nov 21; (43):4501-3. PMID: 17971969.
      View in: PubMed
    11. Barry GD, Suen JY, Low HB, Pfeiffer B, Flanagan B, Halili M, Le G, Fairlie DP. A refined agonist pharmacophore for protease activated receptor 2. Bioorg Med Chem Lett. 2007 Oct 15; 17(20):5552-7. PMID: 17765542.
      View in: PubMed
    12. Blakeney JS, Reid RC, Le G, Fairlie DP. Nonpeptidic ligands for peptide-activated G protein-coupled receptors. Chem Rev. 2007 Jul; 107(7):2960-3041. PMID: 17622179.
      View in: PubMed
    13. Becker B, Condie GC, Le G, Meutermans W. Carbohydrate-based scaffolds in drug discovery. Mini Rev Med Chem. 2006 Dec; 6(12):1299-309. PMID: 17168806.
      View in: PubMed
    14. Meutermans W, Le G, Becker B. Carbohydrates as scaffolds in drug discovery. ChemMedChem. 2006 Nov; 1(11):1164-94. PMID: 16983718.
      View in: PubMed
    15. Le G, Abbenante G, Madala PK, Hoang HN, Fairlie DP. Organic azide inhibitors of cysteine proteases. J Am Chem Soc. 2006 Sep 27; 128(38):12396-7. PMID: 16984172.
      View in: PubMed
    16. Barry GD, Le G, Fairlie DP. Agonists and antagonists of protease activated receptors (PARs). Curr Med Chem. 2006; 13(3):243-65. PMID: 16475935.
      View in: PubMed
    17. Le G, Abbenante G. Inhibitors of TACE and Caspase-1 as anti-inflammatory drugs. Curr Med Chem. 2005; 12(25):2963-77. PMID: 16378499.
      View in: PubMed
    18. Le G, Abbenante G, Becker B, Grathwohl M, Halliday J, Tometzki G, Zuegg J, Meutermans W. Molecular diversity through sugar scaffolds. Drug Discov Today. 2003 Aug 01; 8(15):701-9. PMID: 12927513.
      View in: PubMed
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