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Gilad Doitsh, PhD

TitleSpecialist-Pediatric Immunology
InstitutionUniversity of California San Francisco
DepartmentSurgery
Address35 Medical Center Way
San Francisco CA 94143
Phone415-476-9326
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    Collapse Biography 
    Collapse Awards and Honors
    UCSF2014  - 2015CFAR Early Career Investigator Award for Excellence in Basic Research.
    The Gladstone Institutes, UCSF2010  - 2011The Gladstone Institute of Virology and Immunology Award for Scientific Excellence

    Collapse Overview 

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 Oct 06; 111:373-381. PMID: 30300855.
      View in: PubMed
    2. Doitsh G, Greene WC. Dissecting How CD4 T Cells Are Lost During HIV Infection. Cell Host Microbe. 2016 Mar 09; 19(3):280-91. PMID: 26962940; PMCID: PMC4835240 [Available on 03/09/17].
      View in: PubMed, PubMed Central
    3. Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Cell Host Microbe. 2015 Oct 14; 18(4):463-70. PMID: 26468749; PMCID: PMC4627664 [Available on 10/14/16].
      View in: PubMed, PubMed Central
    4. Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC. Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells. Cell Rep. 2015 Sep 08; 12(10):1555-1563. PMID: 26321639; PMCID: PMC4565731.
      View in: PubMed, PubMed Central
    5. Geng X, Doitsh G, Yang Z, Galloway NL, Greene WC. Efficient delivery of lentiviral vectors into resting human CD4 T cells. Gene Ther. 2014 Apr; 21(4):444-9. PMID: 24572792; PMCID: PMC4006095.
      View in: PubMed, PubMed Central
    6. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2014 Jan 23; 505(7484):509-14. PMID: 24356306; PMCID: PMC4047036.
      View in: PubMed, PubMed Central
    7. Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014 Jan 24; 343(6169):428-32. PMID: 24356113; PMCID: PMC3976200.
      View in: PubMed, PubMed Central
    8. Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC. Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell. 2010 Nov 24; 143(5):789-801. PMID: 21111238; PMCID: PMC3026834.
      View in: PubMed, PubMed Central
    9. Doitsh G, Shaul Y. Enhancer I predominance in hepatitis B virus gene expression. Mol Cell Biol. 2004 Feb; 24(4):1799-808. PMID: 14749394; PMCID: PMC344184.
      View in: PubMed, PubMed Central
    10. Doitsh G, Shaul Y. A long HBV transcript encoding pX is inefficiently exported from the nucleus. Virology. 2003 May 10; 309(2):339-49. PMID: 12758180.
      View in: PubMed
    11. Shamay M, Barak O, Doitsh G, Ben-Dor I, Shaul Y. Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription. J Biol Chem. 2002 Mar 22; 277(12):9982-8. PMID: 11788598.
      View in: PubMed
    12. Doitsh G, Shaul Y. HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX. Oncogene. 1999 Dec 09; 18(52):7506-13. PMID: 10602509.
      View in: PubMed
    13. Haviv I, Shamay M, Doitsh G, Shaul Y. Hepatitis B virus pX targets TFIIB in transcription coactivation. Mol Cell Biol. 1998 Mar; 18(3):1562-9. PMID: 9488473; PMCID: PMC108871.
      View in: PubMed, PubMed Central
    14. Ori A, Zauberman A, Doitsh G, Paran N, Oren M, Shaul Y. p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53. EMBO J. 1998 Jan 15; 17(2):544-53. PMID: 9430645; PMCID: PMC1170404.
      View in: PubMed, PubMed Central
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