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Gill Hirst, PhD

TitleSPECIALIST
SchoolUCSF School of Medicine
DepartmentSurgery
Address1600 Divisadero
San Francisco CA 94115
Phone415-353-7504
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    Collapse Research 
    Collapse Research Activities and Funding
    Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancers
    NIH/NCI U01CA196406Sep 16, 2015 - Aug 31, 2020
    Role: Co-Investigator
    Modeling the Impact of Targeted Therapy Based on Breast Cancer Subtypes
    NIH/NCI U01CA187945Sep 18, 2014 - Aug 31, 2019
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O & van ‘t Veer, L. . DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. npj Breast Cancer. 2017; 31(3).
    2. Quigley DA, Kandyba E, Huang P, Halliwill KD, Sjölund J, Pelorosso F, Wong CE, Hirst G, Wu D, Delrosario R, Kumar A, Balmain A, et al. Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer. Cell Rep. 2016 Jul 26; 16(4):1153-65. PMID: 27425619.
      View in: PubMed
    3. Rugo HS, Olopade OI, DeMichele A, Yau C, van 't Veer LJ, Buxton MB, Hogarth M, Hylton NM, Paoloni M, Perlmutter J, Symmans WF, Yee D, Chien AJ, Wallace AM, Kaplan HG, Boughey JC, Haddad TC, Albain KS, Liu MC, Isaacs C, Khan QJ, Lang JE, Viscusi RK, Pusztai L, Moulder SL, Chui SY, Kemmer KA, Elias AD, Edmiston KK, Euhus DM, Haley BB, Nanda R, Northfelt DW, Tripathy D, Wood WC, Ewing C, Schwab R, Lyandres J, Davis SE, Hirst G, Sanil A, Berry DA, Esserman LJ. Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer. N Engl J Med. 2016 Jul 07; 375(1):23-34. PMID: 27406347.
      View in: PubMed
    4. Park JW, Liu MC, Yee D, Yau C, van 't Veer LJ, Symmans WF, Paoloni M, Perlmutter J, Hylton NM, Hogarth M, DeMichele A, Buxton MB, Chien AJ, Wallace AM, Boughey JC, Haddad TC, Chui SY, Kemmer KA, Kaplan HG, Isaacs C, Nanda R, Tripathy D, Albain KS, Edmiston KK, Elias AD, Northfelt DW, Pusztai L, Moulder SL, Lang JE, Viscusi RK, Euhus DM, Haley BB, Khan QJ, Wood WC, Melisko M, Schwab R, Helsten T, Lyandres J, Davis SE, Hirst G, Sanil A, Esserman LJ, Berry DA. Adaptive Randomization of Neratinib in Early Breast Cancer. N Engl J Med. 2016 Jul 07; 375(1):11-22. PMID: 27406346.
      View in: PubMed
    5. McCreery MQ, Halliwill KD, Chin D, Delrosario R, Hirst G, Vuong P, Jen KY, Hewinson J, Adams DJ, Balmain A. Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Nat Med. 2015 Dec; 21(12):1514-20. PMID: 26523969.
      View in: PubMed
    6. Hirst G, Balmain A. Forty years of cancer modelling in the mouse. Eur J Cancer. 2004 Sep; 40(13):1974-80. PMID: 15315806.
      View in: PubMed
    7. Hirst G, Illand M. Automated fluorescent detection of microsatellite instability. Mol Biotechnol. 2001 Mar; 17(3):239-47. PMID: 11434312.
      View in: PubMed
    8. Hirst G, Brown R. Detection of the Replication Error Phenotype in Ovarian Cancer-PCR Analysis of Microsatellite Instability. Methods Mol Med. 2001; 39:375-82. PMID: 21340793.
      View in: PubMed
    9. Durant ST, Morris MM, Illand M, McKay HJ, McCormick C, Hirst G, Borts RH, Brown R. Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes. Curr Biol. 1999 Jan 14; 9(1):51-4. PMID: 9889125.
      View in: PubMed
    10. Hirst G. PCR analysis of microsatellite instability. Methods Mol Med. 1999; 28:155-65. PMID: 21374036.
      View in: PubMed
    11. Simpson BJ, Langdon SP, Rabiasz GJ, Macleod KG, Hirst G, Bartlett JM, Crew AJ, Hawkins RA, Macineira-Perez PP, Smyth JF, Miller WR. Estrogen regulation of transforming growth factor-alpha in ovarian cancer. J Steroid Biochem Mol Biol. 1998 Feb; 64(3-4):137-45. PMID: 9605408.
      View in: PubMed
    12. Brown R, Hirst G, Gallagher WM, McIlwrath AJ, Margison GP, van der Zee AG, Anthoney DA. hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene. 1997 Jul 03; 15(1):45-52. PMID: 9233776.
      View in: PubMed
    13. Langdon SP, Rabiasz GJ, Hirst G, King RJ, Hawkins RA, Smyth JF, Miller WR. Expression of the heat shock protein HSP27 in human ovarian cancer. Clin Cancer Res. 1995 Dec; 1(12):1603-9. PMID: 9815962.
      View in: PubMed
    14. Bartlett J, Rabiasz G, Scott W, Langdon S, Hirst G, Lee A, Smyth J, Miller W. Growth-control of human ovarian-carcinoma cells by insulin-like growth-factors. Oncol Rep. 1995 Sep; 2(5):857-62. PMID: 21597831.
      View in: PubMed
    15. Langdon SP, Hirst G, Miller EP, Hawkins RA, Tesdale AL, Smyth JF, Miller WR. The regulation of growth and protein expression by estrogen in vitro: a study of 8 human ovarian carcinoma cell lines. J Steroid Biochem Mol Biol. 1994 Aug; 50(3-4):131-5. PMID: 8049141.
      View in: PubMed
    16. Jepson MA, Simmons NL, Hirst GL, Hirst G. Identification of M cells and their distribution in rabbit intestinal Peyer's patches and appendix. Cell Tissue Res. 1993 Jul; 273(1):127-36. PMID: 8364955.
      View in: PubMed
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