Giuseppe Cullaro, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Phone415-353-2318
ORCID ORCID Icon0000-0002-2935-0245 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Boston University, Boston, MABS05/2009Biochemistry and Molecular Biology
    Boston University School of Medicine, Boston, MAMD05/2013
    New York Presbyterian—Columbia University, New York, NY06/2016Internal Medicine Residency
    University of California, San Francisco, San Francisco, CA06/2019Gastroenterology Fellowship
    University of California, San Francisco, San Francisco, CAMAS06/2019Masters in Clinical Research
    New York Presbyterian—Cornell and Columbia University, New York, NY06/2020Advanced/Transplant Hepatology
    Collapse Awards and Honors
    Boston University School of Medicine2013Alpha Omega Alpha
    New York Presbyterian—Columbia University2015House Staff Teaching Award
    American College of Gastroenterology2017GI Jeopardy Champion
    American Transplant Congress2019Young Investigator Award
    American Association For The Study Of Liver Disease2019AASLD Foundation Advanced/Transplant Hepatology Award
    American Association For The Study Of Liver Disease2019AASLD Early Career Investigator Award in Clinical/Translational Science

    Collapse Overview 
    Collapse Overview
    I am a gastroenterologist and transplant hepatologist who cares for patients with general hepatology and transplant hepatology needs.

    My academic interests lie at the intersection of hepatology and nephrology. Specifically, I focus on improving outcomes for patients with end-stage liver disease by identifying predictive markers of future kidney dysfunction—markers that may inform the mechanism of disease pathogenesis and allow for the implementation of preventative strategies.

    I earned my undergraduate and medical degrees from Boston University. I completed a residency in Internal Medicine at New York Presbyterian—Columbia University, followed by a gastroenterology fellowship at UCSF, and a transplant hepatology fellowship at New York Presbyterian—Cornell and Columbia University in 2020. I obtained a Master of Advanced Studies in Clinical Research through the UCSF Graduate Division in 2019.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Biomarkers to Identify Advanced Kidney Dysfunction Among Outpatients with Cirrhosis
    AASLD AASLD Foundation Advanced/Transplant Hepatology AwJul 1, 2019 - Jul 1, 2021
    Role: PI
    Description: The goal of this study is to investigate novel biomarkers of future advanced kidney dysfunction among patients with end-stage liver disease.

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Controversies in terlipressin and transplantation in the United States: How do we MELD the two? Liver Transpl. 2024 Mar 28. Przybyszewski EM, Wilechansky RM, McLean Diaz P, Allegretti AS, VanWagner LB, Cullaro G, Levitsky J, Ginès P, Piano S, Asrani SK, Patidar KR, from the HRS-Harmony Consortium. PMID: 38537069.
      View in: PubMed   Mentions:    Fields:    
    2. Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among cirrhosis patients. Liver Transpl. 2024 Mar 27. Cullaro G, Chiou SH, Fenton C, Ge J, McCulloch CE, Rubin J, Shui AM, Yao F, Lai JC. PMID: 38535488.
      View in: PubMed   Mentions:    Fields:    
    3. The association between mean arterial pressure and acute kidney injury reversal among decompensated cirrhosis patients. Hepatology. 2024 Mar 27. Cullaro G, Allegretti AS, Fenton C, Ge J, Patidar KR, Rubin J, Sharma A, Lai JC. PMID: 38537129.
      View in: PubMed   Mentions:    Fields:    
    4. From past to present to future: Terlipressin and hepatorenal syndrome-acute kidney injury. Hepatology. 2024 Feb 14. Allegretti AS, Patidar KR, Ma AT, Cullaro G. PMID: 38353565.
      View in: PubMed   Mentions:    Fields:    
    5. Association between neighborhood-based material deprivation and liver transplant waitlist registrants demographics and mortality. Clin Transplant. 2024 Jan; 38(1):e15189. Cullaro G, Ge J, Lee BP, Lai JC, Wadhwani SI. PMID: 37937349; PMCID: PMC10842435.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Nonselective beta-blockers may lead to stage 2 acute kidney injury and waitlist mortality in child class C cirrhosis. Hepatol Commun. 2023 10 01; 7(10). Lai M, Fenton C, Ge J, Rubin J, Lai JC, Cullaro G. PMID: 37756037; PMCID: PMC10531476.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Prognostic significance of acute kidney injury stage 1B in hospitalized patients with cirrhosis: A US nationwide study. Liver Transpl. 2024 03 01; 30(3):244-253. Patidar KR, Cullaro G, Naved MA, Kabir S, Grama A, Orman ES, Piano S, Allegretti AS. PMID: 37556190; PMCID: PMC10853477.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States. J Clin Gastroenterol. 2023 08 01; 57(7):731-736. Wang M, Wadhwani SI, Cullaro G, Lai JC, Rubin JB. PMID: 35997698; PMCID: PMC9938839.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation. J Clin Gastroenterol. 2024 May-Jun 01; 58(5):516-521. Wang M, Ge J, Ha N, Shui AM, Huang CY, Cullaro G, Lai JC. PMID: 37279205; PMCID: PMC10700658.
      View in: PubMed   Mentions:    Fields:    
    10. Reply: Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis. Hepatology. 2023 08 01; 78(2):E35-E36. Cullaro G. PMID: 37119206.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Longer time to recovery from acute kidney injury is associated with major adverse kidney events in patients with cirrhosis. Aliment Pharmacol Ther. 2023 06; 57(12):1397-1406. Patidar KR, Naved MA, Kabir S, Grama A, Allegretti AS, Cullaro G, Asrani SK, Worden A, Desai AP, Ghabril MS, Nephew LD, Orman ES. PMID: 36883210; PMCID: PMC10441172.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Recent Advances in the Management of Hepatorenal Syndrome: A US Perspective. Clin Gastroenterol Hepatol. 2023 04; 21(4):897-901.e1. Patidar KR, Piano S, Cullaro G, Belcher JM, Allegretti AS, HRS-Harmony Consortia. PMID: 36801201; PMCID: PMC10038893.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Women with cirrhosis have lower self-rated health than men. Hepatol Commun. 2023 03 01; 7(3):e0065. Wang M, Huang CY, Cullaro G, Covinsky K, Lai JC. PMID: 36757393; PMCID: PMC9916108.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Much Ado About Something: The Clinical Pattern of Tolvaptan-Associated Liver Injury in Participants With ADPKD. Am J Kidney Dis. 2023 03; 81(3):259-260. Postalcioglu M, Cullaro G, Park M. PMID: 36528464.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Multicenter assessment of hypertension management among liver transplantation recipients. Liver Transpl. 2023 01 01; 29(1):122-124. Chebrolu S, Phipps M, Yao F, Lai J, Verna E, Serper M, Cullaro G, Asrani SK, VanWagner LB. PMID: 35839287.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium. Transplant Direct. 2022 Dec; 8(12):e1408. Barman PM, Patel YA, Xie J, Zhang M, Jo J, Sinha J, Answine A, Schluger A, Walter K, Biggins SW, Cullaro G, Wong R, Lai JC, VanWagner LB, Magee J, Verna EC, Sharma P. PMID: 36398193; PMCID: PMC9666195.
      View in: PubMed   Mentions:
    17. Factors associated with cardiovascular events after simultaneous liver-kidney transplant from the US Multicenter Simultaneous Liver-Kidney Transplant Consortium. Hepatol Commun. 2023 01 01; 7(1):e2108. Jo J, Crespo G, Gregory D, Sinha J, Xie J, Zhang M, Magee J, Barman P, Patel YA, Schluger A, Walters K, Biggins S, Filipek N, Cullaro G, Wong R, Lai JC, Perreault GJ, Verna EC, Sharma P, VanWagner LB. PMID: 36285830; PMCID: PMC9827959.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Acute Kidney Injury in Patients with Liver Disease. Clin J Am Soc Nephrol. 2022 11; 17(11):1674-1684. Cullaro G, Kanduri SR, Velez JCQ. PMID: 35902128; PMCID: PMC9718035.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium. Liver Transpl. 2022 11; 28(11):1756-1765. Sharma P, Xie J, Wang L, Zhang M, Magee J, Answine A, Barman P, Jo J, Sinha J, Schluger A, Perreault GJ, Walters KE, Cullaro G, Wong R, Filipek N, Biggins SW, Lai JC, VanWagner LB, Verna EC, Patel YA. PMID: 35665591.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis. Hepatology. 2022 10; 76(4):1069-1078. Cullaro G, Hsu CY, Lai JC. PMID: 35357707; PMCID: PMC10321149.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Timing of Acute Kidney Injury Recovery a Promising Indicator of Outcomes After Liver Transplantation. Transplantation. 2022 04 01; 106(4):700-701. Cullaro G. PMID: 34172645.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Improving the Model for End-Stage Liver Disease with sodium by incorporating kidney dysfunction types. Hepatology. 2022 09; 76(3):689-699. Cullaro G, Verna EC, McCulloch CE, Lai JC. PMID: 35298079; PMCID: PMC9378344.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Discordance in categorization of acute-on-chronic liver failure in the United Network for Organ Sharing database. J Hepatol. 2022 05; 76(5):1122-1126. Lee BP, Cullaro G, Vosooghi A, Yao F, Panchal S, Goldberg DS, Terrault NA, Mahmud N. PMID: 35074470; PMCID: PMC9018597.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Sex-based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation. Transplantation. 2021 11 01; 105(11):2420-2426. Cullaro G, Rubin J, Mehta N, Yao F, Verna EC, Lai JC. PMID: 33323764; PMCID: PMC8200371.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Frailty and the Risk of Acute Kidney Injury Among Patients With Cirrhosis. Hepatol Commun. 2022 04; 6(4):910-919. Cullaro G, Verna EC, Duarte-Rojo A, Kappus MR, Ganger DR, Rahimi RS, Boyarsky B, Segev DL, McAdams-DeMarco M, Ladner DP, Volk ML, Hsu CY, Lai JC. PMID: 34676697; PMCID: PMC8948591.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    26. Estimating Glomerular Filtration Rate in Cirrhosis: A Variable Science That Needs Clinical Awareness. Liver Transpl. 2021 11; 27(11):1525-1526. Cullaro G, Verna EC. PMID: 34411404.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US SLKT Consortium. Liver Transpl. 2021 11; 27(11):1613-1622. Cullaro G, Sharma P, Jo J, Rassiwala J, VanWagner LB, Wong R, Lai JC, Magee J, Schluger A, Barman P, Patel YA, Walter K, Biggins SW, Verna EC. PMID: 34265161; PMCID: PMC8982673.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis. Dig Dis Sci. 2022 07; 67(7):3426-3435. Cullaro G, Rubin JB, Fortune BE, Crawford CV, Verna EC, Hsu CY, Liu KD, Brown RS, Lai JC, Rosenblatt R. PMID: 34292470; PMCID: PMC9568372.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium. Liver Transpl. 2021 08; 27(8):1144-1153. Sharma P, Sui Z, Zhang M, Magee JC, Barman P, Patel Y, Schluger A, Walter K, Biggins SW, Cullaro G, Wong R, Lai JC, Jo J, Sinha J, VanWagner L, Verna EC. PMID: 33641218; PMCID: PMC8823286.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Early Kidney Allograft Failure After Simultaneous Liver-kidney Transplantation: Evidence for Utilization of the Safety Net? Transplantation. 2021 04 01; 105(4):816-823. Cullaro G, Verna EC, Emond JC, Orandi BJ, Mohan S, Lai JC. PMID: 32413016; PMCID: PMC7971118.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Women who undergo liver transplant have longer length of stay post-transplant compared with men. Liver Int. 2020 07; 40(7):1725-1735. Rubin JB, Cullaro G, Ge J, Lai JC. PMID: 32412164; PMCID: PMC7968877.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation. Clin Transplant. 2020 06; 34(6):e13848. Sheshadri A, Cullaro G, Johansen KL, Lai JC. PMID: 32112458; PMCID: PMC10123007.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes. Liver Transpl. 2020 04; 26(4):498-506. Cullaro G, Verna EC, Lee BP, Lai JC. PMID: 31785069; PMCID: PMC8056970.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    34. Not All Episodes of Acute Kidney Injury Are Equal in Patients With Cirrhosis, Based on Patterns of Renal Dysfunction. Clin Gastroenterol Hepatol. 2020 07; 18(8):1694-1695. Cullaro G, Asrani SK. PMID: 32184186.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. A Comprehensive Review of Outcome Predictors in Low MELD Patients. Transplantation. 2020 02; 104(2):242-250. Mazumder NR, Atiemo K, Kappus M, Cullaro G, Harinstein ME, Ladner D, Verna E, Lai J, Levitsky J. PMID: 31517785; PMCID: PMC6994330.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes. Liver Transpl. 2020 02; 26(2):283-293. Cullaro G, Sharma R, Trebicka J, Cárdenas A, Verna EC. PMID: 31714011; PMCID: PMC8046290.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma. Liver Transpl. 2020 03; 26(3):349-358. Cullaro G, Rubin JB, Mehta N, Lai JC. PMID: 31610089; PMCID: PMC7036008.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes. Transplantation. 2019 05; 103(5):959-964. Cullaro G, Hirose R, Lai JC. PMID: 30086097; PMCID: PMC6363909.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. National Trends and Long-term Outcomes of Liver Transplant for Alcohol-Associated Liver Disease in the United States. JAMA Intern Med. 2019 03 01; 179(3):340-348. Lee BP, Vittinghoff E, Dodge JL, Cullaro G, Terrault NA. PMID: 30667468; PMCID: PMC6439700.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    40. Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2019 10; 17(11):2364-2370. Cullaro G, Verna EC, Lai JC. PMID: 30716479; PMCID: PMC6675672.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    41. "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis. Hepatology. 2018 11; 68(5):1953-1960. Cullaro G, Park M, Lai JC. PMID: 29698588; PMCID: PMC6203679.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    42. Early Postoperative Neutrophil Gelatinase-Associated Lipocalin Predicts the Development of Chronic Kidney Disease After Liver Transplantation. Transplantation. 2018 05; 102(5):809-815. Cullaro G, Pisa JF, Brown RS, Wagener G, Verna EC. PMID: 29300232; PMCID: PMC5924424.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Sex-based disparities in delisting for being "too sick" for liver transplantation. Am J Transplant. 2018 05; 18(5):1214-1219. Cullaro G, Sarkar M, Lai JC. PMID: 29194969; PMCID: PMC5910224.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    44. Ascites Neutrophil Gelatinase-Associated Lipocalin Identifies Spontaneous Bacterial Peritonitis and Predicts Mortality in Hospitalized Patients with Cirrhosis. Dig Dis Sci. 2017 12; 62(12):3487-3494. Cullaro G, Kim G, Pereira MR, Brown RS, Verna EC. PMID: 29098551.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    45. Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B. J Hepatol. 2017 02; 66(2):275-281. Lai CL, Wong D, Ip P, Kopaniszen M, Seto WK, Fung J, Huang FY, Lee B, Cullaro G, Chong CK, Wu R, Cheng C, Yuen J, Ngai V, Yuen MF. PMID: 27639844.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    46. Knockdown of heme oxygenase-2 impairs corneal epithelial cell wound healing. J Cell Physiol. 2011 Jul; 226(7):1732-40. Halilovic A, Patil KA, Bellner L, Marrazzo G, Castellano K, Cullaro G, Dunn MW, Schwartzman ML. PMID: 21506105; PMCID: PMC3078528.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    47. Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury. Invest Ophthalmol Vis Sci. 2008 Aug; 49(8):3379-86. Patil K, Bellner L, Cullaro G, Gotlinger KH, Dunn MW, Schwartzman ML. PMID: 18441305; PMCID: PMC2574648.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
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