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Haifan Wu, PhD

Title(s)Postdoctoral Scholar, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address555 Mission Bay Blvd South
San Francisco CA 94158
Phone415-502-0338
ORCID ORCID Icon0000-0002-2050-9950 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of South FloridaPhD05/2015Bioorganic chemistry
    Nanjing University, ChinaBS06/2010Chemistry

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Glutamine Side Chain 13C-18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly. J Am Chem Soc. 2019 05 08; 141(18):7320-7326. Wu H, Saltzberg DJ, Kratochvil HT, Jo H, Sali A, DeGrado WF. PMID: 30998340.
      View in: PubMed   Mentions:    Fields:    
    2. Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals. J Am Chem Soc. 2019 03 20; 141(11):4526-4530. Zhang Q, Schepis A, Huang H, Yang J, Ma W, Torra J, Zhang SQ, Yang L, Wu H, Nonell S, Dong Z, Kornberg TB, Coughlin SR, Shu X. PMID: 30821975.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Exposing the Nucleation Site in a-Helix Folding: A Joint Experimental and Simulation Study. J Phys Chem B. 2019 02 28; 123(8):1797-1807. Acharyya A, Ge Y, Wu H, DeGrado WF, Voelz VA, Gai F. PMID: 30694671.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    4. Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry. Proc Natl Acad Sci U S A. 2018 10 30; 115(44):11162-11167. Yang B, Wu H, Schnier PD, Liu Y, Liu J, Wang N, DeGrado WF, Wang L. PMID: 30322930.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    5. Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins. Angew Chem Int Ed Engl. 2018 09 24; 57(39):12702-12706. Liu J, Cheng R, Wu H, Li S, Wang PG, DeGrado WF, Rozovsky S, Wang L. PMID: 30118570.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Design of a Short Thermally Stable a-Helix Embedded in a Macrocycle. Chembiochem. 2018 05 04; 19(9):902-906. Wu H, Acharyya A, Wu Y, Liu L, Jo H, Gai F, DeGrado WF. PMID: 29417711.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    7. De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):10852-10857. Dang B, Wu H, Mulligan VK, Mravic M, Wu Y, Lemmin T, Ford A, Silva DA, Baker D, DeGrado WF. PMID: 28973862.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Zinc-binding structure of a catalytic amyloid from solid-state NMR. Proc Natl Acad Sci U S A. 2017 06 13; 114(24):6191-6196. Lee M, Wang T, Makhlynets OV, Wu Y, Polizzi NF, Wu H, Gosavi PM, Stöhr J, Korendovych IV, DeGrado WF, Hong M. PMID: 28566494.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    9. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nat Chem. 2017 09; 9(9):874-881. Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. PMID: 28837163.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Inserting CO2 into Aryl C-H Bonds of Metal-Organic Frameworks: CO2 Utilization for Direct Heterogeneous C-H Activation. Angew Chem Int Ed Engl. 2016 04 25; 55(18):5472-6. Gao WY, Wu H, Leng K, Sun Y, Ma S. PMID: 27080057.
      View in: PubMed   Mentions: 2     Fields:    
    11. RGD mimetics ?-AApeptides and methods of use (US 20,140,004,039 A1): a patent evaluation. Expert Opin Ther Pat. 2016; 26(1):131-7. Wu H, Jiang J, Xu H, Li Q, Cai J. PMID: 26560186.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    12. New Class of Heterogeneous Helical Peptidomimetics. Org Lett. 2015 Jul 17; 17(14):3524-7. Wu H, Qiao Q, Teng P, Hu Y, Antoniadis D, Zuo X, Cai J. PMID: 26153619.
      View in: PubMed   Mentions: 8     Fields:    
    13. Helical Antimicrobial Sulfono-?-AApeptides. J Med Chem. 2015 Jun 11; 58(11):4802-11. Li Y, Wu H, Teng P, Bai G, Lin X, Zuo X, Cao C, Cai J. PMID: 26020456.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    14. The synthesis of head-to-tail cyclic sulfono-?-AApeptides. Org Biomol Chem. 2015 Jan 21; 13(3):672-6. Wu H, She F, Gao W, Prince A, Li Y, Wei L, Mercer A, Wojtas L, Ma S, Cai J. PMID: 25420701.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    15. Sulfono-?-AApeptides as a new class of nonnatural helical foldamer. Chemistry. 2015 Feb 02; 21(6):2501-7. Wu H, Qiao Q, Hu Y, Teng P, Gao W, Zuo X, Wojtas L, Larsen RW, Ma S, Cai J. PMID: 25504756.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    16. Antimicrobial ?-AApeptides (WO2013112548): a patent evaluation. Expert Opin Ther Pat. 2015 Jan; 25(1):111-8. Teng P, Wu H, Lin L, Cai J. PMID: 25331592.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Design, synthesis and characterization of fMLF-mimicking AApeptides. Chembiochem. 2014 Nov 03; 15(16):2420-6. Hu Y, Cheng N, Wu H, Kang S, Ye RD, Cai J. PMID: 25224835.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    18. Short antimicrobial lipo-a/?-AA hybrid peptides. Chembiochem. 2014 Oct 13; 15(15):2275-80. Li Y, Smith C, Wu H, Teng P, Shi Y, Padhee S, Jones T, Nguyen AM, Cao C, Yin H, Cai J. PMID: 25169879.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    19. Identification of novel inhibitors that disrupt STAT3-DNA interaction from a ?-AApeptide OBOC combinatorial library. Chem Commun (Camb). 2014 Aug 14; 50(63):8739-42. Teng P, Zhang X, Wu H, Qiao Q, Sebti SM, Cai J. PMID: 24964402.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    20. The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. Chembiochem. 2014 Mar 21; 15(5):688-94. Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. PMID: 24677440.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Lipidated cyclic ?-AApeptides display both antimicrobial and anti-inflammatory activity. ACS Chem Biol. 2014 Jan 17; 9(1):211-7. Li Y, Smith C, Wu H, Padhee S, Manoj N, Cardiello J, Qiao Q, Cao C, Yin H, Cai J. PMID: 24144063.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    22. ?-AApeptide-based small-molecule ligands that inhibit Aß aggregation. Chem Commun (Camb). 2014 May 25; 50(40):5206-8. Wu H, Li Y, Bai G, Niu Y, Qiao Q, Tipton JD, Cao C, Cai J. PMID: 24158240.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    23. Polymyxin derivatives: a patent evaluation (WO2012168820). Expert Opin Ther Pat. 2013 Aug; 23(8):1075-81. Wu H, Teng P, Niu Y, Li Q, Cai J. PMID: 23806121.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    24. AApeptides as a new class of antimicrobial agents. Org Biomol Chem. 2013 Jul 14; 11(26):4283-90. Niu Y, Wu H, Li Y, Hu Y, Padhee S, Li Q, Cao C, Cai J. PMID: 23722277.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    25. Synthesis of AApeptides. Methods Mol Biol. 2013; 1081:35-46. Niu Y, Hu Y, Wu H, Cai J. PMID: 24014432.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    26. Recent development of small antimicrobial peptidomimetics. Future Med Chem. 2012 Sep; 4(14):1853-62. Niu Y, Wang RE, Wu H, Cai J. PMID: 23043481.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    27. Radiolabeled ?-AApeptides: a new class of tracers for positron emission tomography. Chem Commun (Camb). 2012 Aug 14; 48(63):7850-2. Yang Y, Niu Y, Hong H, Wu H, Zhang Y, Engle JW, Barnhart TE, Cai J, Cai W. PMID: 22785080.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    28. Solid-phase synthesis of ?-AApeptides using a submonomeric approach. Org Lett. 2012 Jul 06; 14(13):3446-9. Wu H, Amin MN, Niu Y, Qiao Q, Harfouch N, Nimer A, Cai J. PMID: 22731678.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    29. Lipo-?-AApeptides as a new class of potent and broad-spectrum antimicrobial agents. J Med Chem. 2012 Apr 26; 55(8):4003-9. Niu Y, Padhee S, Wu H, Bai G, Qiao Q, Hu Y, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. PMID: 22475244.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    30. Cellular translocation of a ?-AApeptide mimetic of Tat peptide. Mol Pharm. 2012 May 07; 9(5):1529-34. Niu Y, Bai G, Wu H, Wang RE, Qiao Q, Padhee S, Buzzeo R, Cao C, Cai J. PMID: 22413929.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    31. Development of NGR-based anti-cancer agents for targeted therapeutics and imaging. Anticancer Agents Med Chem. 2012 Jan; 12(1):76-86. Wang RE, Niu Y, Wu H, Hu Y, Cai J. PMID: 22023047.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    32. Development of self-immolative dendrimers for drug delivery and sensing. J Control Release. 2012 Apr 30; 159(2):154-63. Wang RE, Costanza F, Niu Y, Wu H, Hu Y, Hang W, Sun Y, Cai J. PMID: 22155555.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    33. Identification of ?-AApeptides with potent and broad-spectrum antimicrobial activity. Chem Commun (Camb). 2011 Nov 28; 47(44):12197-12199. Niu Y, Padhee S, Wu H, Bai G, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. PMID: 21963627.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    34. ?-AApeptides bind to RNA by mimicking RNA-binding proteins. Org Biomol Chem. 2011 Oct 07; 9(19):6604-9. Niu Y, Jones AJ, Wu H, Varani G, Cai J. PMID: 21826330.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    35. Non-hemolytic a-AApeptides as antimicrobial peptidomimetics. Chem Commun (Camb). 2011 Sep 14; 47(34):9729-31. Padhee S, Hu Y, Niu Y, Bai G, Wu H, Costanza F, West L, Harrington L, Shaw LN, Cao C, Cai J. PMID: 21779608.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    36. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011; 1(1):36-46. Wang RE, Niu Y, Wu H, Amin MN, Cai J. PMID: 23133793.
      View in: PubMed   Mentions:
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