 Haifan Wu, PhD
 Biography | University of South Florida | PhD | 05/2015 | Bioorganic chemistry | | Nanjing University, China | BS | 06/2010 | Chemistry |
Bibliographic
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Wu H, Saltzberg DJ, Kratochvil HT, Jo H, Sali A, DeGrado WF. Glutamine Side Chain 13C-18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly. J Am Chem Soc. 2019 May 08; 141(18):7320-7326. PMID: 30998340.
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Zhang Q, Schepis A, Huang H, Yang J, Ma W, Torra J, Zhang SQ, Yang L, Wu H, Nonell S, Dong Z, Kornberg TB, Coughlin SR, Shu X. Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals. J Am Chem Soc. 2019 Mar 20; 141(11):4526-4530. PMID: 30821975.
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Acharyya A, Ge Y, Wu H, DeGrado WF, Voelz VA, Gai F. Exposing the Nucleation Site in a-Helix Folding: A Joint Experimental and Simulation Study. J Phys Chem B. 2019 02 28; 123(8):1797-1807. PMID: 30694671.
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Yang B, Wu H, Schnier PD, Liu Y, Liu J, Wang N, DeGrado WF, Wang L. Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry. Proc Natl Acad Sci U S A. 2018 10 30; 115(44):11162-11167. PMID: 30322930.
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Liu J, Cheng R, Wu H, Li S, Wang PG, DeGrado WF, Rozovsky S, Wang L. Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins. Angew Chem Int Ed Engl. 2018 09 24; 57(39):12702-12706. PMID: 30118570.
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Wu H, Acharyya A, Wu Y, Liu L, Jo H, Gai F, DeGrado WF. Design of a Short Thermally Stable a-Helix Embedded in a Macrocycle. Chembiochem. 2018 05 04; 19(9):902-906. PMID: 29417711.
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Dang B, Wu H, Mulligan VK, Mravic M, Wu Y, Lemmin T, Ford A, Silva DA, Baker D, DeGrado WF. De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):10852-10857. PMID: 28973862.
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Lee M, Wang T, Makhlynets OV, Wu Y, Polizzi NF, Wu H, Gosavi PM, Stöhr J, Korendovych IV, DeGrado WF, Hong M. Zinc-binding structure of a catalytic amyloid from solid-state NMR. Proc Natl Acad Sci U S A. 2017 06 13; 114(24):6191-6196. PMID: 28566494.
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Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nat Chem. 2017 09; 9(9):874-881. PMID: 28837163.
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Gao WY, Wu H, Leng K, Sun Y, Ma S. Inserting CO2 into Aryl C-H Bonds of Metal-Organic Frameworks: CO2 Utilization for Direct Heterogeneous C-H Activation. Angew Chem Int Ed Engl. 2016 04 25; 55(18):5472-6. PMID: 27080057.
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Wu H, Jiang J, Xu H, Li Q, Cai J. RGD mimetics ?-AApeptides and methods of use (US 20,140,004,039 A1): a patent evaluation. Expert Opin Ther Pat. 2016; 26(1):131-7. PMID: 26560186.
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Wu H, Qiao Q, Teng P, Hu Y, Antoniadis D, Zuo X, Cai J. New Class of Heterogeneous Helical Peptidomimetics. Org Lett. 2015 Jul 17; 17(14):3524-7. PMID: 26153619.
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Li Y, Wu H, Teng P, Bai G, Lin X, Zuo X, Cao C, Cai J. Helical Antimicrobial Sulfono-?-AApeptides. J Med Chem. 2015 Jun 11; 58(11):4802-11. PMID: 26020456.
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Wu H, She F, Gao W, Prince A, Li Y, Wei L, Mercer A, Wojtas L, Ma S, Cai J. The synthesis of head-to-tail cyclic sulfono-?-AApeptides. Org Biomol Chem. 2015 Jan 21; 13(3):672-6. PMID: 25420701.
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Wu H, Qiao Q, Hu Y, Teng P, Gao W, Zuo X, Wojtas L, Larsen RW, Ma S, Cai J. Sulfono-?-AApeptides as a new class of nonnatural helical foldamer. Chemistry. 2015 Feb 02; 21(6):2501-7. PMID: 25504756.
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Teng P, Wu H, Lin L, Cai J. Antimicrobial ?-AApeptides (WO2013112548): a patent evaluation. Expert Opin Ther Pat. 2015 Jan; 25(1):111-8. PMID: 25331592.
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Hu Y, Cheng N, Wu H, Kang S, Ye RD, Cai J. Design, synthesis and characterization of fMLF-mimicking AApeptides. Chembiochem. 2014 Nov 03; 15(16):2420-6. PMID: 25224835.
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Li Y, Smith C, Wu H, Teng P, Shi Y, Padhee S, Jones T, Nguyen AM, Cao C, Yin H, Cai J. Short antimicrobial lipo-a/?-AA hybrid peptides. Chembiochem. 2014 Oct 13; 15(15):2275-80. PMID: 25169879.
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Teng P, Zhang X, Wu H, Qiao Q, Sebti SM, Cai J. Identification of novel inhibitors that disrupt STAT3-DNA interaction from a ?-AApeptide OBOC combinatorial library. Chem Commun (Camb). 2014 Aug 14; 50(63):8739-42. PMID: 24964402.
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Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. Chembiochem. 2014 Mar 21; 15(5):688-94. PMID: 24677440.
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Li Y, Smith C, Wu H, Padhee S, Manoj N, Cardiello J, Qiao Q, Cao C, Yin H, Cai J. Lipidated cyclic ?-AApeptides display both antimicrobial and anti-inflammatory activity. ACS Chem Biol. 2014 Jan 17; 9(1):211-7. PMID: 24144063.
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Wu H, Li Y, Bai G, Niu Y, Qiao Q, Tipton JD, Cao C, Cai J. ?-AApeptide-based small-molecule ligands that inhibit Aß aggregation. Chem Commun (Camb). 2014 May 25; 50(40):5206-8. PMID: 24158240.
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Wu H, Teng P, Niu Y, Li Q, Cai J. Polymyxin derivatives: a patent evaluation (WO2012168820). Expert Opin Ther Pat. 2013 Aug; 23(8):1075-81. PMID: 23806121.
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Niu Y, Wu H, Li Y, Hu Y, Padhee S, Li Q, Cao C, Cai J. AApeptides as a new class of antimicrobial agents. Org Biomol Chem. 2013 Jul 14; 11(26):4283-90. PMID: 23722277.
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Niu Y, Hu Y, Wu H, Cai J. Synthesis of AApeptides. Methods Mol Biol. 2013; 1081:35-46. PMID: 24014432.
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Niu Y, Wang RE, Wu H, Cai J. Recent development of small antimicrobial peptidomimetics. Future Med Chem. 2012 Sep; 4(14):1853-62. PMID: 23043481.
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Yang Y, Niu Y, Hong H, Wu H, Zhang Y, Engle JW, Barnhart TE, Cai J, Cai W. Radiolabeled ?-AApeptides: a new class of tracers for positron emission tomography. Chem Commun (Camb). 2012 Aug 14; 48(63):7850-2. PMID: 22785080.
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Wu H, Amin MN, Niu Y, Qiao Q, Harfouch N, Nimer A, Cai J. Solid-phase synthesis of ?-AApeptides using a submonomeric approach. Org Lett. 2012 Jul 06; 14(13):3446-9. PMID: 22731678.
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Niu Y, Padhee S, Wu H, Bai G, Qiao Q, Hu Y, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. Lipo-?-AApeptides as a new class of potent and broad-spectrum antimicrobial agents. J Med Chem. 2012 Apr 26; 55(8):4003-9. PMID: 22475244.
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Niu Y, Bai G, Wu H, Wang RE, Qiao Q, Padhee S, Buzzeo R, Cao C, Cai J. Cellular translocation of a ?-AApeptide mimetic of Tat peptide. Mol Pharm. 2012 May 07; 9(5):1529-34. PMID: 22413929.
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Wang RE, Niu Y, Wu H, Hu Y, Cai J. Development of NGR-based anti-cancer agents for targeted therapeutics and imaging. Anticancer Agents Med Chem. 2012 Jan; 12(1):76-86. PMID: 22023047.
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Wang RE, Costanza F, Niu Y, Wu H, Hu Y, Hang W, Sun Y, Cai J. Development of self-immolative dendrimers for drug delivery and sensing. J Control Release. 2012 Apr 30; 159(2):154-63. PMID: 22155555.
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Niu Y, Padhee S, Wu H, Bai G, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. Identification of ?-AApeptides with potent and broad-spectrum antimicrobial activity. Chem Commun (Camb). 2011 Nov 28; 47(44):12197-12199. PMID: 21963627.
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Niu Y, Jones AJ, Wu H, Varani G, Cai J. ?-AApeptides bind to RNA by mimicking RNA-binding proteins. Org Biomol Chem. 2011 Oct 07; 9(19):6604-9. PMID: 21826330.
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Padhee S, Hu Y, Niu Y, Bai G, Wu H, Costanza F, West L, Harrington L, Shaw LN, Cao C, Cai J. Non-hemolytic a-AApeptides as antimicrobial peptidomimetics. Chem Commun (Camb). 2011 Sep 14; 47(34):9729-31. PMID: 21779608.
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Wang RE, Niu Y, Wu H, Amin MN, Cai J. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011; 1(1):36-46. PMID: 23133793.
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