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Hao Shao, PhD

Title(s)Specialist, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-7073
ORCID ORCID Icon0000-0003-4437-5536 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Differential scanning fluorimetry (DSF) screen to identify inhibitors of Hsp60 protein-protein interactions. Org Biomol Chem. 2020 Jun 10; 18(22):4157-4163. Shao H, Oltion K, Wu T, Gestwicki JE. PMID: 32458889.
      View in: PubMed   Mentions: 1     Fields:    
    2. A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography. ACS Chem Biol. 2020 06 19; 15(6):1381-1391. Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Blecha JE, VanBrocklin HF, Seo Y, Sayeed M, Feldman BJ, Aggarwal R, Behr SC, Shao H, Wilson DM, Villanueva-Meyer JE, Gestwicki JE, Evans MJ. PMID: 32255605.
      View in: PubMed   Mentions:    Fields:    
    3. Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98. Bioorg Med Chem Lett. 2020 03 01; 30(5):126954. Shao H, Gestwicki JE. PMID: 31952963.
      View in: PubMed   Mentions:    Fields:    
    4. Inhibitors and chemical probes for molecular chaperone networks. J Biol Chem. 2019 02 08; 294(6):2151-2161. Gestwicki JE, Shao H. PMID: 30213856.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    5. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26; 61(14):6163-6177. Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers L, Gestwicki JE. PMID: 29953808.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    6. Rational design and screening of peptide-based inhibitors of heat shock factor 1 (HSF1). Bioorg Med Chem. 2018 10 15; 26(19):5299-5306. Ran X, Burchfiel ET, Dong B, Rettko NJ, Dunyak BM, Shao H, Thiele DJ, Gestwicki JE. PMID: 29661622.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex. J Biol Chem. 2018 03 16; 293(11):4014-4025. Taylor IR, Dunyak BM, Komiyama T, Shao H, Ran X, Assimon VA, Kalyanaraman C, Rauch JN, Jacobson MP, Zuiderweg ERP, Gestwicki JE. PMID: 29414793.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    8. Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells. Cancer Res. 2016 10 15; 76(20):5926-5932. Gabai VL, Yaglom JA, Wang Y, Meng L, Shao H, Kim G, Colvin T, Gestwicki J, Sherman MY. PMID: 27503927.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    9. Protein Cross-Linking Capillary Electrophoresis for Protein-Protein Interaction Analysis. Anal Chem. 2016 08 16; 88(16):8272-8. Ouimet CM, Shao H, Rauch JN, Dawod M, Nordhues B, Dickey CA, Gestwicki JE, Kennedy RT. PMID: 27434096.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    10. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. Int J Antimicrob Agents. 2016 Apr; 47(4):289-96. Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. PMID: 27013001.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    11. Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70). Curr Top Med Chem. 2016; 16(25):2729-40. Li X, Shao H, Taylor IR, Gestwicki JE. PMID: 27072701.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    12. Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. Medchemcomm. 2015 May 01; 6(5):912-918. Assimon VA, Shao H, Garneau-Tsodikova S, Gestwicki JE. PMID: 27087913.
      View in: PubMed   Mentions:
    13. Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73. Oncotarget. 2014 Sep 15; 5(17):7691-704. Lam F, Abbas AY, Shao H, Teo T, Adams J, Li P, Bradshaw TD, Fischer PM, Walsby E, Pepper C, Chen Y, Ding J, Wang S. PMID: 25277198.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    14. A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine. Oncotarget. 2014 Jan 30; 5(2):375-85. Walsby E, Pratt G, Shao H, Abbas AY, Fischer PM, Bradshaw TD, Brennan P, Fegan C, Wang S, Pepper C. PMID: 24495868.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    15. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. Eur J Med Chem. 2013; 70:447-55. Shao H, Shi S, Foley DW, Lam F, Abbas AY, Liu X, Huang S, Jiang X, Baharin N, Fischer PM, Wang S. PMID: 24185375.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    16. Comparative structural and functional studies of 4-(thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 inhibitors suggest the basis for isotype selectivity. J Med Chem. 2013 Feb 14; 56(3):660-70. Hole AJ, Baumli S, Shao H, Shi S, Huang S, Pepper C, Fischer PM, Wang S, Endicott JA, Noble ME. PMID: 23252711.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure-activity relationship, and anticancer activities. J Med Chem. 2013 Feb 14; 56(3):640-59. Shao H, Shi S, Huang S, Hole AJ, Abbas AY, Baumli S, Liu X, Lam F, Foley DW, Fischer PM, Noble M, Endicott JA, Pepper C, Wang S. PMID: 23301767.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    18. Synthesis and biological evaluation of imidazo[4,5-b]pyridine and 4-heteroaryl-pyrimidine derivatives as anti-cancer agents. Eur J Med Chem. 2012 Nov; 57:311-22. Lukasik PM, Elabar S, Lam F, Shao H, Liu X, Abbas AY, Wang S. PMID: 23085105.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Anti-inflammatory activity of Gentiana striata Maxim. Nat Prod Res. 2012; 26(11):1038-44. Cao F, Shao H, Li Q, Li J, Li W, Li C. PMID: 21985356.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
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