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Hengameh Shams, PhD

Title(s)Postdoctoral Scholar, Neurology
SchoolSchool of Medicine
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, Berkeley, BerkeleyPh.D.2016Applied Science and Technology
    Sharif University of Technology, Tehran, IranM.S.2009Physics/Biophysics
    University of Tehran, Tehran, IranB.S.2007Physics
    Collapse Awards and Honors
    American Society of Cell Biology2019Travel Grant
    University of California, Berkeley2017Berkeley Postdoctoral Association Professional Development Award
    Biophysical Society2016Biophysical Society Committee on Diversity and Inclusion Travel Award
    University of California2015  - 2016The UC Dissertation Fellowship
    University of California, Berkeley2011  - 2013Chancellor’s Fellowship

    Collapse Research 
    Collapse Research Activities and Funding
    Characterization of the interplay between T and B lymphocytes in multiple sclerosis using functional proteomics
    National Multiple Sclerosis Society FG-1807-31603Jul 1, 2019 - Jun 30, 2022
    Role: Investigator
    Characterization of the interplay between T and B lymphocytes in multiple sclerosis using functional proteomics guided by genotype-phenotype association models
    UCSF-CTSI Postdoctoral Fellowship 5TL1TR001871-04Jul 1, 2019 - Jun 30, 2020
    Role: Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Haydari Z, Shams H, Jahed Z, Mofrad MRK. Kindlin Assists Talin to Promote Integrin Activation. Biophys J. 2020 Mar 03. PMID: 32191864.
      View in: PubMed
    2. Harris AR, Belardi B, Jreij P, Wei K, Shams H, Bausch A, Fletcher DA. Steric regulation of tandem calponin homology domain actin-binding affinity. Mol Biol Cell. 2019 12 15; 30(26):3112-3122. PMID: 31693446.
      View in: PubMed
    3. Van Agthoven JF, Shams H, Cochran FV, Alonso JL, Kintzing JR, Garakani K, Adair BD, Xiong JP, Mofrad MRK, Cochran JR, Arnaout MA. Structural Basis of the Differential Binding of Engineered Knottins to Integrins aVß3 and a5ß1. Structure. 2019 09 03; 27(9):1443-1451.e6. PMID: 31353240.
      View in: PubMed
    4. Didonna A, Cantó E, Shams H, Isobe N, Zhao C, Caillier SJ, Condello C, Yamate-Morgan H, Tiwari-Woodruff SK, Mofrad MRK, Hauser SL, Oksenberg JR. Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation. J Autoimmun. 2019 Jul; 101:56-69. PMID: 31010726.
      View in: PubMed
    5. Shams H, Hoffman BD, Mofrad MRK. The "Stressful" Life of Cell Adhesion Molecules: On the Mechanosensitivity of Integrin Adhesome. J Biomech Eng. 2018 02 01; 140(2). PMID: 29272321.
      View in: PubMed
    6. Shams H, Mofrad MRK. a-Actinin Induces a Kink in the Transmembrane Domain of ß3-Integrin and Impairs Activation via Talin. Biophys J. 2017 Aug 22; 113(4):948-956. PMID: 28834730.
      View in: PubMed
    7. H. Shams, M. Soheilypour, M. Peyro, R. Moussavi-Baygi, M. R. K. Mofrad.Looking “Under the Hood” of Cellular Mechanotransduction with Computational Tools: A Systems Biomechanics Approach across Multiple Scales. ACS Biomater. Sci. Eng. . 2017; 3(11):2712-2726.
    8. Garakani K, Shams H, Mofrad MRK. Mechanosensitive Conformation of Vinculin Regulates Its Binding to MAPK1. Biophys J. 2017 May 09; 112(9):1885-1893. PMID: 28494959.
      View in: PubMed
    9. Shams H, Golji J, Garakani K, Mofrad MR. Dynamic Regulation of a-Actinin's Calponin Homology Domains on F-Actin. Biophys J. 2016 Mar 29; 110(6):1444-55. PMID: 27028653.
      View in: PubMed
    10. Boyer PD, Shams H, Baker SL, Mofrad MRK, Islam MF, Dahl KN. Enhanced intracellular delivery of small molecules and drugs via non-covalent ternary dispersions of single-wall carbon nanotubes. J Mater Chem B. 2016 Feb 21; 4(7):1324-1330. PMID: 32262987.
      View in: PubMed
    11. P. D. Boyer, H. Shams, S. L. Baker, M. R. K. Mofrad, M. F. Islam, K. N. Dahl.Enhanced intracellular delivery of small molecules and drugs via non-covalent ternary dispersions of single-wall carbon nanotubes. J. Mater. Chem. B. 2016; 4:1324.
    12. Jahed Z, Shams H, Mofrad MR. A Disulfide Bond Is Required for the Transmission of Forces through SUN-KASH Complexes. Biophys J. 2015 Aug 04; 109(3):501-9. PMID: 26244732.
      View in: PubMed
    13. Truong T, Shams H, Mofrad MR. Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation. Integr Biol (Camb). 2015 Oct; 7(10):1285-96. PMID: 26156744.
      View in: PubMed
    14. Jahed Z, Shams H, Mehrbod M, Mofrad MR. Mechanotransduction pathways linking the extracellular matrix to the nucleus. Int Rev Cell Mol Biol. 2014; 310:171-220. PMID: 24725427.
      View in: PubMed
    15. Shams H, Holt BD, Mahboobi SH, Jahed Z, Islam MF, Dahl KN, Mofrad MR. Actin reorganization through dynamic interactions with single-wall carbon nanotubes. ACS Nano. 2014 Jan 28; 8(1):188-97. PMID: 24351114.
      View in: PubMed
    16. Shams H, Golji J, Mofrad MR. A molecular trajectory of a-actinin activation. Biophys J. 2012 Nov 21; 103(10):2050-9. PMID: 23200039.
      View in: PubMed
    17. Holt BD, Shams H, Horst TA, Basu S, Rape AD, Wang YL, Rohde GK, Mofrad MR, Islam MF, Dahl KN. Altered cell mechanics from the inside: dispersed single wall carbon nanotubes integrate with and restructure actin. J Funct Biomater. 2012 May 23; 3(2):398-417. PMID: 24955540.
      View in: PubMed
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