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Hirofumi Noguchi, PhD

Title(s)Postdoctoral Scholar, Neurology
SchoolSchool of Medicine
Phone415-514-4949
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Noguchi H, Miyagi-Shiohira C, Nakashima Y, Ebi N, Hamada E, Tamaki Y, Kuwae K, Kitamura S, Kobayashi N, Saitoh I, Watanabe M. A novel preservation solution containing a JNK inhibitory peptide efficiently improves islet yield for porcine islet isolation. Transplantation. 2018 Dec 20. PMID: 30557272.
      View in: PubMed
    2. Nahar S, Nakashima Y, Miyagi-Shiohira C, Kinjo T, Toyoda Z, Kobayashi N, Saitoh I, Watanabe M, Noguchi H, Fujita J. Cytokines in adipose-derived mesenchymal stem cells promote the healing of liver disease. World J Stem Cells. 2018 Nov 26; 10(11):146-159. PMID: 30631390.
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    3. Nakashima Y, Nahar S, Miyagi-Shiohira C, Kinjo T, Toyoda Z, Kobayashi N, Saitoh I, Watanabe M, Fujita J, Noguchi H. A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of the Proteins Secreted by Human Adipose-Derived Mesenchymal Stem Cells. Cell Transplant. 2018 Oct; 27(10):1469-1494. PMID: 30226075.
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    4. Nahar S, Nakashima Y, Miyagi-Shiohira C, Kinjo T, Kobayashi N, Saitoh I, Watanabe M, Noguchi H, Fujita J. A Comparison of the Preservation of Mouse Adipose Tissue-Derived Mesenchymal Stem Cells Using the University of Wisconsin Solution and Hank's Balanced Salt Solution. Stem Cells Int. 2018; 2018:1625464. PMID: 30258463.
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    5. Nakashima Y, Miyagi-Shiohira C, Noguchi H, Omasa T. The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson's Disease. Brain Sci. 2018 Aug 31; 8(9). PMID: 30200351.
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    6. Miyagi-Shiohira C, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Noguchi H. Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA. Sci Rep. 2018 Aug 17; 8(1):12341. PMID: 30120295.
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    7. Hamada E, Ebi N, Miyagi-Shiohira C, Tamaki Y, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Kinjo T, Noguchi H. Comparison Between Modified Extracellular-Type Trehalose-Containing Kyoto Solution and University of Wisconsin Solution in 18-Hour Pancreas Preservation for Islet Transplantation. Pancreas. 2018 08; 47(7):e46-e47. PMID: 29985851.
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    8. Noguchi H, Miyagi-Shiohira C, Nakashima Y, Ebi N, Hamada E, Tamaki Y, Kuwae K, Kobayashi N, Saitoh I, Watanabe M. Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation. Sci Rep. 2018 Jul 23; 8(1):11082. PMID: 30038242.
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    9. Nakashima Y, Nahar S, Miyagi-Shiohira C, Kinjo T, Kobayashi N, Saitoh I, Watanabe M, Fujita J, Noguchi H. A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Cells Cultured in DMEM 10% FBS and Chemically Defined Medium Using Human Adipose-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2018 Jul 13; 19(7). PMID: 30011845.
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    10. Nakashima Y, Miyagi-Shiohira C, Noguchi H, Omasa T. Atorvastatin Inhibits the HIF1a-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells. Mol Ther. 2018 Jul 05; 26(7):1715-1734. PMID: 29929789.
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    11. Murao N, Matsubara S, Matsuda T, Noguchi H, Mutoh T, Mutoh M, Koseki H, Namihira M, Nakashima K. Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain. Neurosci Res. 2018 May 31. PMID: 29859850.
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    12. Nakashima Y, Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi H. Adhesion characteristics of porcine pancreatic islets and exocrine tissue to coating materials. Islets. 2018 05 04; 10(3):e1460294. PMID: 29757700.
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    13. Noguchi H, Miyagi-Shiohira C, Nakashima Y. Induced Tissue-Specific Stem Cells and Epigenetic Memory in Induced Pluripotent Stem Cells. Int J Mol Sci. 2018 Mar 21; 19(4). PMID: 29561778.
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    14. Nakashima Y, Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi H. A proteome analysis of pig pancreatic islets and exocrine tissue by liquid chromatography with tandem mass spectrometry. Islets. 2017 11 02; 9(6):159-176. PMID: 29099648.
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    15. Kawamura Y, Katada S, Noguchi H, Yamamoto H, Sanosaka T, Iihara K, Nakashima K. Synergistic induction of astrocytic differentiation by factors secreted from meninges in the mouse developing brain. FEBS Lett. 2017 11; 591(22):3709-3720. PMID: 29029363.
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    16. Xu J, Sadahira T, Kinoshita R, Li SA, Huang P, Wada K, Araki M, Ochiai K, Noguchi H, Sakaguchi M, Nasu Y, Watanabe M. Exogenous DKK-3/REIC inhibits Wnt/ß-catenin signaling and cell proliferation in human kidney cancer KPK1. Oncol Lett. 2017 Nov; 14(5):5638-5642. PMID: 29098038.
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    17. Noguchi H, Sugimoto K, Miyagi-Shiohira C, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y. RCAN-11R peptide provides immunosuppression for fully mismatched islet allografts in mice. Sci Rep. 2017 06 08; 7(1):3043. PMID: 28596584.
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    18. Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda-Andoh T, Okano H, Nakashima K. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017 06 06; 8(6):1743-1756. PMID: 28591654.
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    19. Murakami T, Saitoh I, Sato M, Inada E, Soda M, Oda M, Domon H, Iwase Y, Sawami T, Matsueda K, Terao Y, Ohshima H, Noguchi H, Hayasaki H. Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers. Arch Oral Biol. 2017 Sep; 81:110-120. PMID: 28500952.
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    20. Noguchi H. Facilitating Transplantation. Cell Med. 2017 Jan 08; 9(1-2):1-2. PMID: 28174668.
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    21. Saitoh I, Sato M, Soda M, Inada E, Iwase Y, Murakami T, Ohshima H, Hayasaki H, Noguchi H. Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose. PLoS One. 2016; 11(9):e0163580. PMID: 27662374.
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    22. Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S. Enhanced Adipogenic Differentiation of Human Adipose-Derived Stem Cells in an In Vitro Microenvironment: The Preparation of Adipose-Like Microtissues Using a Three-Dimensional Culture. Cell Med. 2017 Jan 08; 9(1-2):35-44. PMID: 28174673.
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    23. Noguchi H, Kimura A, Murao N, Namihira M, Nakashima K. Prenatal deletion of DNA methyltransferase 1 in neural stem cells impairs neurogenesis and causes anxiety-like behavior in adulthood. Neurogenesis (Austin). 2016; 3(1):e1232679. PMID: 27844025.
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    24. Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H. Comparison of Purification Solutions With Different Osmolality for Porcine Islet Purification. Cell Med. 2017 Jan 08; 9(1-2):53-59. PMID: 28174675.
      View in: PubMed
    25. Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H. Evaluation of Serum-Free, Xeno-Free Cryopreservation Solutions for Human Adipose-Derived Mesenchymal Stem Cells. Cell Med. 2017 Jan 08; 9(1-2):15-20. PMID: 28174671.
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    26. Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H. The Evaluation of Islet Purification Methods That Use Large Bottles to Create a Continuous Density Gradient. Cell Med. 2017 Jan 08; 9(1-2):45-51. PMID: 28174674.
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    27. Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I. Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions. Nat Biotechnol. 2016 Oct; 34(10):1060-1065. PMID: 27571369.
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    28. Noguchi H, Murao N, Kimura A, Matsuda T, Namihira M, Nakashima K. DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus. J Neurosci. 2016 06 01; 36(22):6050-68. PMID: 27251626.
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    29. Noguchi H. Creating a Future of Transplantation. Cell Med. 2015 Dec 17; 8(1-2):1. PMID: 26858902; PMCID: PMC4733905.
      View in: PubMed, PubMed Central
    30. Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H. Cryopreservation of Adipose-Derived Mesenchymal Stem Cells. Cell Med. 2015 Dec 17; 8(1-2):3-7. PMID: 26858903; PMCID: PMC4733906.
      View in: PubMed, PubMed Central
    31. Noguchi H, Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M. Islet Culture/Preservation Before Islet Transplantation. Cell Med. 2015 Dec 17; 8(1-2):25-9. PMID: 26858905; PMCID: PMC4733908.
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    32. Saitoh I, Inada E, Iwase Y, Noguchi H, Murakami T, Soda M, Kubota N, Hasegawa H, Akasaka E, Matsumoto Y, Oka K, Yamasaki Y, Hayasaki H, Sato M. Choice of Feeders Is Important When First Establishing iPSCs Derived From Primarily Cultured Human Deciduous Tooth Dental Pulp Cells. Cell Med. 2015 Dec 17; 8(1-2):9-23. PMID: 26858904.
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    33. Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S. Spheroid Formation and Evaluation of Hepatic Cells in a Three-Dimensional Culture Device. Cell Med. 2015 Dec 17; 8(1-2):47-56. PMID: 26858908.
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    34. Noguchi H, Kimura A, Murao N, Matsuda T, Namihira M, Nakashima K. Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus. Neurosci Res. 2015 Jun; 95:1-11. PMID: 25659757.
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    35. Tsugata T, Nikoh N, Kin T, Saitoh I, Noguchi Y, Ueki H, Watanabe M, James Shapiro AM, Noguchi H. Potential Factors for the Differentiation of ESCs/iPSCs Into Insulin-Producing Cells. Cell Med. 2015 Feb 08; 7(2):83-93. PMID: 26858897; PMCID: PMC4733840.
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    36. Noguchi H. Basic and Clinical Science for Organ Biology. Cell Med. 2015 Feb 08; 7(2):49. PMID: 26858892; PMCID: PMC4733835.
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    37. Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S. Three-Dimensional In Vitro Hepatic Constructs Formed Using Combinatorial Tapered Stencil for Cluster Culture (TASCL) Device. Cell Med. 2015 Feb 08; 7(2):67-74. PMID: 26858895.
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    38. Murao N, Matsuda T, Noguchi H, Koseki H, Namihira M, Nakashima K. Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells. Neurogenesis (Austin). 2014; 1(1):e976026. PMID: 27504471; PMCID: PMC4973607.
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    39. Yukawa H, Nakagawa S, Yoshizumi Y, Watanabe M, Saito H, Miyamoto Y, Noguchi H, Oishi K, Ono K, Sawada M, Kato I, Onoshima D, Obayashi M, Hayashi Y, Kaji N, Ishikawa T, Hayashi S, Baba Y. Novel positively charged nanoparticle labeling for in vivo imaging of adipose tissue-derived stem cells. PLoS One. 2014; 9(11):e110142. PMID: 25365191.
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    40. Shimoda M, Chen S, Noguchi H, Takita M, Sugimoto K, Itoh T, Chujo D, Iwahashi S, Naziruddin B, Levy MF, Matsumoto S, Grayburn PA. A new method for generating insulin-secreting cells from human pancreatic epithelial cells after islet isolation transformed by NeuroD1. Hum Gene Ther Methods. 2014 Jun; 25(3):206-19. PMID: 24845703.
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    41. Kuise T, Noguchi H, Tazawa H, Kawai T, Iwamuro M, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells. Biomed Eng Online. 2014 May 27; 13:64. PMID: 24886514.
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    42. Adefuin AM, Kimura A, Noguchi H, Nakashima K, Namihira M. Epigenetic mechanisms regulating differentiation of neural stem/precursor cells. Epigenomics. 2014; 6(6):637-49. PMID: 25531257.
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    43. Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei FY, Hakim F, Kume S, Tomizawa K. Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors. Stem Cells Transl Med. 2014 Jan; 3(1):114-27. PMID: 24292793; PMCID: PMC3902286.
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    44. Murakami T, Saitoh I, Inada E, Kurosawa M, Iwase Y, Noguchi H, Terao Y, Yamasaki Y, Hayasaki H, Sato M. STO Feeder Cells Are Useful for Propagation of Primarily Cultured Human Deciduous Dental Pulp Cells by Eliminating Contaminating Bacteria and Promoting Cellular Outgrowth. Cell Med. 2013 Dec 30; 6(1-2):75-81. PMID: 26858883; PMCID: PMC4735889.
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    45. Noguchi H. Organ Biology-New Development. Cell Med. 2013 Dec 30; 6(1-2):1-2. PMID: 26858873; PMCID: PMC4735879.
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    46. Kawai T, Noguchi H, Kuise T, Nakatsuka A, Katayama A, Imagawa N, Kataoka HU, Saitoh I, Noguchi Y, Watanabe M, Fujiwara T. Comparison of Incubation Solutions Prior to the Purification of Porcine Islet Cells. Cell Med. 2013 Dec 30; 6(1-2):9-14. PMID: 26858875.
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    47. Katayama A, Noguchi H, Kuise T, Nakatsuka A, Hirota D, Kataoka HU, Kawai T, Inoue K, Imagawa N, Saitoh I, Noguchi Y, Watanabe M, Wada J, Fujiwara T. Comparison of New Preservation Solutions, HN-1 and University of Wisconsin Solution, in Pancreas Preservation for Porcine Islet Isolation. Cell Med. 2013 Dec 30; 6(1-2):3-8. PMID: 26858874.
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    48. Kubota Y, Noguchi H, Seita M, Yuasa T, Sasamoto H, Nakaji S, Okitsu T, Fujiwara T, Kobayashi N. Maintenance of Viability and Function of Rat Islets With the Use of ROCK Inhibitor Y-27632. Cell Med. 2013 Dec 30; 6(1-2):15-23. PMID: 26858876.
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    49. Seita M, Noguchi H, Kubota Y, Kawamoto H, Nakaji S, Kobayashi N, Fujiwara T. Development of Canine Models of Type 1 Diabetes With Partial Pancreatectomy and the Administration of Streptozotocin. Cell Med. 2013 Dec 30; 6(1-2):25-31. PMID: 26858877.
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    50. Yuniarti N, Juliandi B, MuhChyi C, Noguchi H, Sanosaka T, Nakashima K. Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis. Neurosci Res. 2013 Sep-Oct; 77(1-2):42-9. PMID: 23831515.
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    51. Noguchi H. Long-Expected New Start. Cell Med. 2013 Nov 10; 5(2-3):43. PMID: 26858863; PMCID: PMC4733853.
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    52. Miyamoto Y, Koshidaka Y, Noguchi H, Oishi K, Saito H, Yukawa H, Kaji N, Ikeya T, Suzuki S, Iwata H, Baba Y, Murase K, Hayashi S. Observation of Positively Charged Magnetic Nanoparticles Inside HepG2 Spheroids Using Electron Microscopy. Cell Med. 2013 Nov 10; 5(2-3):89-96. PMID: 26858871.
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    53. Kataoka HU, Noguchi H. ER Stress and ß-Cell Pathogenesis of Type 1 and Type 2 Diabetes and Islet Transplantation. Cell Med. 2013 Nov 10; 5(2-3):53-7. PMID: 26858865; PMCID: PMC4733855.
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    54. Noguchi H, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Culture Conditions for Mouse Pancreatic Stem Cells. Cell Med. 2013 Nov 10; 5(2-3):63-8. PMID: 26858867.
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    55. Kuise T, Noguchi H, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Isolation Efficiency of Mouse Pancreatic Stem Cells Is Age Dependent. Cell Med. 2013 Nov 10; 5(2-3):69-73. PMID: 26858868.
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    56. Oishi K, Miyamoto Y, Saito H, Murase K, Ono K, Sawada M, Watanabe M, Noguchi Y, Fujiwara T, Hayashi S, Noguchi H. In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle. PLoS One. 2013; 8(2):e57046. PMID: 23451139.
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    57. Huang P, Watanabe M, Kaku H, Ueki H, Noguchi H, Sugimoto M, Hirata T, Yamada H, Takei K, Zheng S, Xu K, Nasu Y, Fujii Y, Liu C, Kumon H. Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line. Mol Clin Oncol. 2013 Jan; 1(1):180-184. PMID: 24649144.
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    58. Sugimoto M, Watanabe M, Kaku H, Li SA, Noguchi H, Ueki H, Sakaguchi M, Huh NH, Nasu Y, Kumon H. Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy. Oncol Rep. 2012 Nov; 28(5):1645-52. PMID: 22941469.
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    59. Noguchi H. Organ/Cell Transplantation and Regenerative Medicine. Cell Med. 2012 Jan; 3(1-3):1-2. PMID: 28058174.
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    60. Yukawa H, Noguchi H, Oishi K, Miyamoto Y, Inoue M, Hasegawa M, Hayashi S, Baba Y. Differentiation of Mouse Pancreatic Stem Cells Into Insulin-Producing Cells by Recombinant Sendai Virus-Mediated Gene Transfer Technology. Cell Med. 2012 Jan; 3(1-3):51-61. PMID: 28058181.
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    61. Saitoh I, Sato M, Iwase Y, Inada E, Nomura T, Akasaka E, Yamasaki Y, Noguchi H. Generation of Mouse STO Feeder Cell Lines That Confer Resistance to Several Types of Selective Drugs. Cell Med. 2012 Jan; 3(1-3):97-102. PMID: 28058186.
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    62. Oishi K, Noguchi H, Saito H, Yukawa H, Miyamoto Y, Ono K, Murase K, Sawada M, Hayashi S. Novel Positive-Charged Nanoparticles for Efficient Magnetic Resonance Imaging of Islet Transplantation. Cell Med. 2012 Jan; 3(1-3):43-49. PMID: 28058180.
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    63. Noguchi H, Naziruddin B, Shimoda M, Chujo D, Takita M, Sugimoto K, Itoh T, Onaca N, Levy MF, Matsumoto S. A Combined Continuous Density/Osmolality Gradient for Supplemental Purification of Human Islets. Cell Med. 2012 Jan; 3(1-3):33-41. PMID: 28058179.
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    64. Miyamoto Y, Noguchi H, Yukawa H, Oishi K, Matsushita K, Iwata H, Hayashi S. Cryopreservation of Induced Pluripotent Stem Cells. Cell Med. 2012 Jan; 3(1-3):89-95. PMID: 28058185.
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    65. Ueki H, Watanabe M, Kaku H, Huang P, Li SA, Ochiai K, Hirata T, Noguchi H, Yamada H, Takei K, Nasu Y, Kashiwakura Y, Kumon H. A novel gene expression system for detecting viable bladder cancer cells. Int J Oncol. 2012 Jul; 41(1):135-40. PMID: 22470055.
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    66. Kanamune J, Iwanaga Y, Kina T, Noguchi H, Matsumura K, Uemoto S, Hyon SH. Attenuation of murine graft-versus-host disease by a tea polyphenol. Cell Transplant. 2012; 21(5):909-18. PMID: 22330060.
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    67. Noguchi H. Stem cell applications in diabetes. J Stem Cells. 2012; 7(4):229-44. PMID: 24196798.
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    68. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Ueda M, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Onaca N, Levy MF, Matsumoto S. Comparison of ulinastatin, gabexate mesilate, and nafamostat mesilate in preservation solution for islet isolation. Cell Transplant. 2012; 21(2-3):509-16. PMID: 22793059.
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    69. Noguchi H, Naziruddin B, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Evaluation of osmolality of density gradient for human islet purification. Cell Transplant. 2012; 21(2-3):493-500. PMID: 22793057.
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    70. Hayashi T, Misawa H, Nakahara H, Noguchi H, Yoshida A, Kobayashi N, Tanaka M, Ozaki T. Transplantation of osteogenically differentiated mouse iPS cells for bone repair. Cell Transplant. 2012; 21(2-3):591-600. PMID: 22793068.
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    71. Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S. Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using a1-antitrypsin. Cell Transplant. 2012; 21(2-3):465-71. PMID: 22793054.
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    72. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Fresh islets are more effective for islet transplantation than cultured islets. Cell Transplant. 2012; 21(2-3):517-23. PMID: 22793060.
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    73. Takita M, Matsumoto S, Noguchi H, Shimoda M, Ikemoto T, Chujo D, Tamura Y, Olsen GS, Naziruddin B, Purcell K, Onaca N, Levy MF. Adverse events in clinical islet transplantation: one institutional experience. Cell Transplant. 2012; 21(2-3):547-51. PMID: 22793063.
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    74. Naziruddin B, Matsumoto S, Noguchi H, Takita M, Shimoda M, Fujita Y, Chujo D, Tate C, Onaca N, Lamont J, Kobayashi N, Levy MF. Improved pancreatic islet isolation outcome in autologous transplantation for chronic pancreatitis. Cell Transplant. 2012; 21(2-3):553-8. PMID: 22793064.
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    75. Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S. Islet purification method using large bottles effectively achieves high islet yield from pig pancreas. Cell Transplant. 2012; 21(2-3):501-8. PMID: 22793058.
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    76. Miyamoto Y, Oishi K, Yukawa H, Noguchi H, Sasaki M, Iwata H, Hayashi S. Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin. Cell Transplant. 2012; 21(2-3):617-22. PMID: 22793071.
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    77. Kuise T, Noguchi H. Recent progress in pancreatic islet transplantation. World J Transplant. 2011 Dec 24; 1(1):13-8. PMID: 24175188.
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    78. Yukawa H, Watanabe M, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Baba Y, Hayashi S. Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots. Biomaterials. 2012 Mar; 33(7):2177-86. PMID: 22192539.
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    79. Noguchi H, Yamada T, Tanaka K. [Islet transplantation]. Nihon Rinsho. 2011 Dec; 69(12):2209-13. PMID: 22242321.
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    80. Obika M, Noguchi H. Diagnosis and evaluation of nonalcoholic fatty liver disease. Exp Diabetes Res. 2012; 2012:145754. PMID: 22110476; PMCID: PMC3205741.
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    81. Takasaki Y, Watanabe M, Yukawa H, Sabarudin A, Inagaki K, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Umemura T, Hayashi S, Baba Y, Haraguchi H. Estimation of the distribution of intravenously injected adipose tissue-derived stem cells labeled with quantum dots in mice organs through the determination of their metallic components by ICPMS. Anal Chem. 2011 Nov 01; 83(21):8252-8. PMID: 21958307.
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    82. Noguchi H. Pancreas procurement and preservation for islet transplantation: personal considerations. J Transplant. 2011; 2011:783168. PMID: 21918716; PMCID: PMC3171759.
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    83. Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H. Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1. Biochem Biophys Res Commun. 2011 Aug 26; 412(2):391-5. PMID: 21835165.
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    164. Izutsu T, Shimotsu S, Matsumoto T, Okada T, Kikuchi A, Kojimoto M, Noguchi H, Yoshikawa K. Deliberate self-harm and childhood hyperactivity in junior high school students. Eur Child Adolesc Psychiatry. 2006 Mar; 15(3):172-6. PMID: 16447027.
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    165. Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JR, Kobayashi E, Tanaka N, Kobayashi N. Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts. Cell Transplant. 2006; 15(4):325-34. PMID: 16898226.
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    166. Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Okitsu T, Chen Y, Tabata Y, Misawa H, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2. Cell Transplant. 2006; 15(10):939-44. PMID: 17299999.
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    167. Miki A, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Tanaka K, Narushima M, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Maintenance of neovascularization at the implantation site of an artificial device by bFGF and endothelial cell transplant. Cell Transplant. 2006; 15(10):893-901. PMID: 17299994.
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    168. Noguchi H, Matsumoto S. Protein transduction technology offers a novel therapeutic approach for diabetes. J Hepatobiliary Pancreat Surg. 2006; 13(4):306-13. PMID: 16858541.
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    169. Matsumoto S, Noguchi H, Yonekawa Y, Okitsu T, Iwanaga Y, Liu X, Nagata H, Kobayashi N, Ricordi C. Pancreatic islet transplantation for treating diabetes. Expert Opin Biol Ther. 2006 Jan; 6(1):23-37. PMID: 16370912.
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    170. Noguchi H, Xu G, Matsumoto S, Kaneto H, Kobayashi N, Bonner-Weir S, Hayashi S. Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant. 2006; 15(10):929-38. PMID: 17299998.
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    171. Noguchi H, Bonner-Weir S, Wei FY, Matsushita M, Matsumoto S. BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence. Diabetes. 2005 Oct; 54(10):2859-66. PMID: 16186386.
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    172. Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H, Lakey JR, Leboulch P, Tanaka N, Yoon JW. A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol. 2005 Oct; 23(10):1274-82. PMID: 16186810.
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    173. Noguchi H, Nakai Y, Matsumoto S, Kawaguchi M, Ueda M, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Minami K, Masui Y, Futaki S, Tanaka K. Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function. Am J Transplant. 2005 Aug; 5(8):1848-55. PMID: 15996231.
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    174. Noguchi H, Matsushita M, Matsumoto S, Lu YF, Matsui H, Bonner-Weir S. Mechanism of PDX-1 protein transduction. Biochem Biophys Res Commun. 2005 Jun 24; 332(1):68-74. PMID: 15896300.
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    175. Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Yamada Y, Fukuda K, Tsukiyama K, Suzuki H, Kawasaki Y, Shimodaira M, Matsuoka K, Shibata T, Kasai Y, Maekawa T, Shapiro J, Tanaka K. Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet. 2005 May 7-13; 365(9471):1642-4. PMID: 15889479.
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    176. Yonekawa Y, Matsumoto S, Okitsu T, Arata T, Iwanaga Y, Noguchi H, Nagata H, O'Neil JJ, Tanaka K. Effective islet isolation method with extremely high islet yields from adult pigs. Cell Transplant. 2005; 14(10):757-62. PMID: 16454350.
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    177. Noguchi H, Matsumoto S, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Matsushita M, Wei FY, Matsui H, Minami K, Seino S, Masui Y, Futaki S, Tanaka K. PDX-1 protein is internalized by lipid raft-dependent macropinocytosis. Cell Transplant. 2005; 14(9):637-45. PMID: 16405074.
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    178. Uetsuka H, Naomoto Y, Fujiwara T, Shirakawa Y, Noguchi H, Yamatsuji T, Haisa M, Matsuoka J, Gunduz M, Takubo K, Tanaka N. Primary malignant melanoma of the esophagus: long-term survival following pre- and postoperative adjuvant hormone/chemotherapy. Dig Dis Sci. 2004 Oct; 49(10):1646-51. PMID: 15573920.
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    179. Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H. Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett. 2004 Aug 13; 572(1-3):221-6. PMID: 15304352.
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    180. Shirakawa Y, Naomoto Y, Noma K, Ono R, Nobuhisa T, Kobayashi M, Fujiwara T, Noguchi H, Ohkawa T, Yamatsuji T, Haisa M, Matsuoka J, Gunduz M, Tanaka N. Free jejunal graft for hypopharyngeal and esophageal reconstruction. Langenbecks Arch Surg. 2004 Oct; 389(5):387-90. PMID: 15605170.
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    181. Matsumura T, Takesue M, Westerman KA, Okitsu T, Sakaguchi M, Fukazawa T, Totsugawa T, Noguchi H, Yamamoto S, Stolz DB, Tanaka N, Leboulch P, Kobayashi N. Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT. Transplantation. 2004 May 15; 77(9):1357-65. PMID: 15167590.
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    182. Noguchi H, Matsushita M, Okitsu T, Moriwaki A, Tomizawa K, Kang S, Li ST, Kobayashi N, Matsumoto S, Tanaka K, Tanaka N, Matsui H. A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat Med. 2004 Mar; 10(3):305-9. PMID: 14770176.
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    183. Matsumoto H, Tanaka K, Noguchi H, Hayakawa Y. Cause of mortality in insects under severe stress. Eur J Biochem. 2003 Aug; 270(16):3469-76. PMID: 12899705.
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    184. Noguchi H, Kaneto H, Weir GC, Bonner-Weir S. PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells. Diabetes. 2003 Jul; 52(7):1732-7. PMID: 12829640.
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    185. Watanabe T, Shibata N, Westerman KA, Okitsu T, Allain JE, Sakaguchi M, Totsugawa T, Maruyama M, Matsumura T, Noguchi H, Yamamoto S, Hikida M, Ohmori A, Reth M, Weber A, Tanaka N, Leboulch P, Kobayashi N. Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers. Transplantation. 2003 Jun 15; 75(11):1873-80. PMID: 12811248.
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    186. Kobayashi O, Sakaguchi M, Okitsu T, Totsugawa T, Maruyama M, Matsumura T, Watanabe T, Noguchi H, Kosaka Y, Fujiwara T, Tanaka N. Improvement in the differentiated hepatic phenotype of immortalized human hepatocytes by adenovirus mediated p21 gene transfer. ASAIO J. 2002 Jul-Aug; 48(4):355-9. PMID: 12141463.
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    187. Noguchi H, Kobayashi N, Westerman KA, Sakaguchi M, Okitsu T, Totsugawa T, Watanabe T, Matsumura T, Fujiwara T, Ueda T, Miyazaki M, Tanaka N, Leboulch P. Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization. Hum Gene Ther. 2002 Jan 20; 13(2):321-34. PMID: 11812287.
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    188. Arikura J, Kobayashi N, Okitsu T, Noguchi H, Totsugawa T, Watanabe T, Matsumura T, Maruyama M, Kosaka Y, Tanaka N, Onodera K, Kasai S. UW solution: a promising tool for cryopreservation of primarily isolated rat hepatocytes. J Hepatobiliary Pancreat Surg. 2002; 9(6):742-9. PMID: 12658410.
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    189. Totsugawa T, Kobayashi N, Okitsu T, Noguchi H, Watanabe T, Matsumura T, Maruyama M, Fujiwara T, Sakaguchi M, Tanaka N. Lentiviral transfer of the LacZ gene into human endothelial cells and human bone marrow mesenchymal stem cells. Cell Transplant. 2002; 11(5):481-8. PMID: 12382678.
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    190. Kunieda T, Kobayashi N, Sakaguchi M, Okitsu T, Totsugawa T, Watanabe T, Matsumura T, Maruyama M, Noguchi H, Takesue M, Shibata N, Ohmoto K, Fujiwara T, Yamamoto S, Tanaka N. Transduction of immortalized human hepatocytes with p21 to enhance differentiated phenotypes. Cell Transplant. 2002; 11(5):421-8. PMID: 12382668.
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    191. Kobayashi N, Noguchi H, Westerman KA, Watanabe T, Matsumura T, Totsugawa T, Fujiwara T, Leboulch P, Tanaka N. Successful Retroviral Gene Transfer of Simian Virus 40 T Antigen and Herpes Simplex Virus-Thymidine Kinase into Human Hepatocytes 1. Cell Transplant. 2001 May/Jul; 10(4-5):377-381. PMID: 28886299.
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    192. Kobayashi N, Noguchi H, Westerman KA, Watanabe T, Matsumura T, Totsugawa T, Fujiwara T, Leboulch P, Tanaka N. Cre/loxP-Based Reversible Immortalization of Human Hepatocytes 1. Cell Transplant. 2001 May/Jul; 10(4-5):383-386. PMID: 28886302.
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