Huong Kratochvil * UCSF Profiles

Huong Kratochvil, PhD

Title(s)	Postdoctoral Scholar, Pharmaceutical Chemistry
School	School of Pharmacy
ORCID	0000-0001-8039-6823
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Biography

Education and Training

The University of Texas at Austin, Austin, TX	B.S.	05/2010	Chemistry
University of Wisconsin-Madison, Madison, WI	Ph.D.	10/2016	Chemistry

Research

Research Activities and Funding

A structural and biophysical study of the matrix proteins in influenza A/B viruses: Mechanisms of proton conduction and roles of protein-protein interactions
NIH/NIGMS F32GM125217Sep 1, 2017 - Aug 31, 2020
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.

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Zhang K, Ahmed IA, Kratochvil HT, DeGrado WF, Gai F, Jo H. Synthesis and application of the blue fluorescent amino acid l-4-cyanotryptophan to assess peptide-membrane interactions. Chem Commun (Camb). 2019 Apr 25; 55(35):5095-5098. PMID: 30957824.

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Wu H, Saltzberg DJ, Kratochvil HT, Jo H, Sali A, DeGrado WF. Glutamine Side Chain 13C-18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly. J Am Chem Soc. 2019 May 08; 141(18):7320-7326. PMID: 30998340.

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Zhang SQ, Huang H, Yang J, Kratochvil HT, Lolicato M, Liu Y, Shu X, Liu L, DeGrado WF. Designed peptides that assemble into cross-a amyloid-like structures. Nat Chem Biol. 2018 09; 14(9):870-875. PMID: 30061717.

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Huong T. Kratochvil, Martin T. Zanni. Two-dimensional infrared (2D IR) spectroscopy for elucidating ion occupancies in the selectivity filter of ion channels1. Biomedical Spectroscopy and Imaging. 2018 May 7; 7(1-2):3-15.

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Huong T. Kratochvil, Jessica L. Thomaston, Feng Gai, William F. DeGrado. Proton Stabilization and Conduction Pathway in the Matrix Protein M2. Biophysical Journal. 2018 Feb 1; 114(3):240a-241a.

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Shao-Qing Zhang, Lijun Liu, Junjiao Yang, Marco Lolicato, Huong Kratochvil, Xiaokun Shu, William F. DeGrado. De Novo Design of Cross-a Amyloid-Like Fibrils with Cellular Activity. Biophysical Journal. 2018 Feb 1; 114(3):410a.

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Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy. J Am Chem Soc. 2017 07 05; 139(26):8837-8845. PMID: 28472884.

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Schneider SH, Kratochvil HT, Zanni MT, Boxer SG. Solvent-Independent Anharmonicity for Carbonyl Oscillators. J Phys Chem B. 2017 03 16; 121(10):2331-2338. PMID: 28225620.

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Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy. Science. 2016 09 02; 353(6303):1040-1044. PMID: 27701114.

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Kratochvil HT, Ha DG, Zanni MT. Counting tagged molecules one by one: Quantitative photoactivation and bleaching of photoactivatable fluorophores. J Chem Phys. 2015 Sep 14; 143(10):104201. PMID: 26374025.

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Buchanan LE, Dunkelberger EB, Tran HQ, Cheng PN, Chiu CC, Cao P, Raleigh DP, de Pablo JJ, Nowick JS, Zanni MT. Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient ß-sheet. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19285-90. PMID: 24218609.

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