Ida Sim, PhD, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
ORCID ORCID Icon0000-0002-1045-8459 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Stanford, CAM.D.1990
    Massachussetts General Hospital, Boston, MA1993Primary Care Internal Medicine Residency
    Stanford University, Stanford, CAPhD1997Medical Informatics
    Stanford University, Stanford, CA1997Fellowship, Health Services Research
    Collapse Awards and Honors
    National Academy of Medicine2022Elected Member
    American Society for Clinical Investigation2010Elected Member
    American College of Medial Informatics2007Elected Fellow
    American Medical Informatics Association2005Leadership Award
    White House Office of Science Technology and Policy2000United States Presidential Early Career Award for Scientists and Engineers

    Collapse Overview 
    Collapse Overview
    Ida Sim, MD, PhD is a primary care physician, informatics researcher, and entrepreneur. She is a Professor of Medicine and UCSF Director of the UCSF UC Berkeley Joint Program in Computational Precision Health. Her other UCSF positions include Director of Digital Health for the Division of General Internal Medicine and Co-Director, Informatics and Research Innovation at UCSF's Clinical and Translational Sciences Institute. Dr. Sim is a global leader in the technology and policy of large-scale health data sharing.

    Dr. Sim is a co-founder of Open mHealth, a non-profit organization that is breaking down barriers to mobile health app and data integration through an open software architecture. Open mHealth is an IEEE family of global standards. IEEE 1752.1 was officially approved in 2021. Dr. Sim has multiple grants from NIH, NSF, and AHRQ on mobile health methodology and digital health for primary care. In 2019, she co-developed CommonHealth, an open source software suite bringing to the Android ecosystem the equivalent of Apple Health's ability to access and share EHR data.

    Dr. Sim is also co-founder of Vivli, the world's largest data sharing platform for participant-level clinical trial data. In 2005, she was the founding Project Coordinator of the World Health Organization's International Clinical Trials Registry Platform, where she led the establishment of the first global policy on clinical trial registration.

    Dr. Sim has served on multiple advisory committees on health information infrastructure for clinical care and research, including committees of the National Research Council and National Academy of Medicine. She is a recipient of the United States Presidential Early Career Award for Scientists and Engineers (PECASE), a Fellow of the American College of Medical Informatics, and a member of the American Society for Clinical Investigation.
    Collapse In The News
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    Collapse Research 
    Collapse Research Activities and Funding
    Mobile Patient-Reported Outcomes for Value and Effectiveness (mPROVE)
    NIH U18HS026883Sep 1, 2019 - Aug 31, 2022
    Role: Principal Investigator
    Open mHealth: Community-Based Data and Metadata Standards for Mobile Health
    NIH R24EB025845Aug 17, 2017 - May 31, 2021
    Role: Principal Investigator
    Ontology-Based Integration of Human Studies Data
    NIH R01RR026040Sep 9, 2009 - May 31, 2013
    Role: Principal Investigator
    The Trial Bank Project
    NIH R01LM006780Jul 1, 1999 - Mar 31, 2011
    Role: Principal Investigator

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    Collapse Clinical Trials
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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      Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
      1. Paging the Clinical Informatics Community: Respond STAT to Dobbs v. Jackson's Women's Health Organization. Appl Clin Inform. 2023 01; 14(1):164-171. Arvisais-Anhalt S, Ravi A, Weia B, Aarts J, Ahmad HB, Araj E, Bauml JA, Benham-Hutchins M, Boyd AD, Brecht-Doscher A, Butler-Henderson K, Butte AJ, Cardilo AB, Chilukuri N, Cho MK, Cohen JK, Craven CK, Crusco S, Dadabhoy F, Dash D, DeBolt C, Elkin PL, Fayanju OA, Fochtmann LJ, Graham JV, Hanna JJ, Hersh W, Hofford MR, Hron JD, Huang SS, Jackson BR, Kaplan B, Kelly W, Ko K, Koppel R, Kurapati N, Labbad G, Lee JJ, Lehmann CU, Leitner S, Liao ZC, Medford RJ, Melnick ER, Muniyappa AN, Murray SG, Neinstein AB, Nichols-Johnson V, Novak LL, Ogan WS, Ozeran L, Pageler NM, Pandita D, Perumbeti A, Petersen C, Pierce L, Puttagunta R, Ramaswamy P, Rogers KM, Rosenbloom ST, Ryan A, Saleh S, Sarabu C, Schreiber R, Shaw KA, Sim I, Sirintrapun SJ, Solomonides A, Spector JD, Starren JB, Stoffel M, Subbian V, Swanson K, Tomes A, Trang K, Unertl KM, Weon JL, Whooley MA, Wiley K, Williamson DFK, Winkelstein P, Wong J, Xie J, Yarahuan JKW, Yung N, Zera C, Ratanawongsa N, Sadasivaiah S. PMID: 36535703; PMCID: PMC9977563.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      2. Data and Computation: A Contemporary Landscape. Intelligent Systems in Medicine and Health. 2022 Nov 10; 51-72. Sim SI, Sirota SM. .
        View in: Publisher Site   Mentions:
      3. Ontology-based categorization of clinical studies by their conditions. J Biomed Inform. 2022 11; 135:104235. Liu H, Carini S, Chen Z, Phillips Hey S, Sim I, Weng C. PMID: 36283581.
        View in: PubMed   Mentions:    Fields:    
      4. Personalized Data Science and Personalized (N-of-1) Trials: Promising Paradigms for Individualized Health Care. Harvard data science review. 2022 Sep 8. Duan DN, Norman ND, Schmid SC, Sim SI, Kravitz KR. .
        View in: Publisher Site   Mentions:
      5. Falling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis. J Clin Invest. 2022 09 01; 132(17). Horwitz RI, Hayes-Conroy A, Singer BH, Cullen MR, Badal K, Sim I. PMID: 36047497; PMCID: PMC9435645.
        View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
      6. Data Sharing and Reuse. . 2022 Jul 20; 2137-2158. Sim SI. .
        View in: Publisher Site   Mentions:
      7. Long COVID and Medicine's Two Cultures. Am J Med. 2022 08; 135(8):945-949. Horwitz RI, Conroy AH, Cullen MR, Colella K, Mawn M, Singer BH, Sim I. PMID: 35417745.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      8. COVID-19 interventional trials: Analysis of data sharing intentions during a time of pandemic. Contemp Clin Trials. 2022 04; 115:106709. Larson K, Sim I, von Isenburg M, Levenstein M, Rockhold F, Neumann S, D'Arcy C, Graham E, Zuckerman D, Li R. PMID: 35182738; PMCID: PMC8847110.
        View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
      9. Standardized Integration of Person-Generated Data Into Routine Clinical Care. JMIR Mhealth Uhealth. 2022 02 10; 10(2):e31048. Zeng B, Bove R, Carini S, Lee JS, Pollak JP, Schleimer E, Sim I. PMID: 35142627; PMCID: PMC8874926.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      10. Biosocial Pathogenesis. Psychother Psychosom. 2022; 91(2):73-77. Horwitz RI, Singer BH, Hayes-Conroy A, Cullen MR, Mawn M, Colella K, Sim I. PMID: 35104822.
        View in: PubMed   Mentions: 2     Fields:    Translation:Humans
      11. Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial. JAMA Cardiol. 2022 02 01; 7(2):167-174. Marcus GM, Modrow MF, Schmid CH, Sigona K, Nah G, Yang J, Chu TC, Joyce S, Gettabecha S, Ogomori K, Yang V, Butcher X, Hills MT, McCall D, Sciarappa K, Sim I, Pletcher MJ, Olgin JE. PMID: 34775507; PMCID: PMC8591553.
        View in: PubMed   Mentions: 15     Fields:    Translation:Humans
      12. Perceptions of Older Men Using a Mobile Health App to Monitor Lower Urinary Tract Symptoms and Tamsulosin Side Effects: Mixed Methods Study. JMIR Hum Factors. 2021 Dec 24; 8(4):e30767. Wang EY, Breyer BN, Lee AW, Rios N, Oni-Orisan A, Steinman MA, Sim I, Kenfield SA, Bauer SR. PMID: 34951599; PMCID: PMC8742207.
        View in: PubMed   Mentions:
      13. Tracking Lower Urinary Tract Symptoms and Tamsulosin Side Effects Among Older Men Using a Mobile App (PERSONAL): Feasibility and Usability Study. JMIR Form Res. 2021 Dec 10; 5(12):e30762. Lee AW, Kenfield SA, Wang EY, Enriquez A, Oni-Orisan A, Steinman MA, Sim I, Breyer BN, Bauer SR. PMID: 34889745; PMCID: PMC8709917.
        View in: PubMed   Mentions:
      14. Rethinking Table 1. J Clin Epidemiol. 2022 02; 142:242-245. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH. PMID: 34800675.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      15. HIPAA and the Leak of "Deidentified" EHR Data. N Engl J Med. 2021 Sep 16; 385(12):e38. Sim I, Cassel C. PMID: 34525298.
        View in: PubMed   Mentions:    Fields:    Translation:Humans
        View in: Publisher Site   Mentions:
      17. Chronic pain treatment preferences change following participation in N-of-1 trials, but not always in the expected direction. J Clin Epidemiol. 2021 11; 139:167-176. Kravitz RL, Marois M, Sim I, Ward D, Kanekar SS, Yu A, Dounias P, Yang J, Wang Y, Schmid CH. PMID: 34400254.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      18. Biosocial medicine: Biology, biography, and the tailored care of the patient. SSM Popul Health. 2021 Sep; 15:100863. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH. PMID: 34430699; PMCID: PMC8374477.
        View in: PubMed   Mentions: 2  
      19. Correction: Data Sharing Goals for Nonprofit Funders of Clinical Trials. J Particip Med. 2021 Jun 30; 13(2):e31371. Coetzee T, Ball MP, Boutin M, Bronson A, Dexter DT, English RA, Furlong P, Goodman AD, Grossman C, Hernandez AF, Hinners JE, Hudson L, Kennedy A, Marchisotto MJ, Matrisian L, Myers E, Nowell WB, Nosek BA, Sherer T, Shore C, Sim I, Smolensky L, Williams C, Wood J, Terry SF. PMID: 34255670; PMCID: PMC8280826.
        View in: PubMed   Mentions:
      20. Mobile Health: making the leap to research and clinics. NPJ Digit Med. 2021 May 14; 4(1):83. Ku JP, Sim I. PMID: 33990671; PMCID: PMC8121913.
        View in: PubMed   Mentions: 6  
      21. Data Sharing Goals for Nonprofit Funders of Clinical Trials. J Particip Med. 2021 Mar 29; 13(1):e23011. Coetzee T, Ball MP, Boutin M, Bronson A, Dexter DT, English RA, Furlong P, Goodman AD, Grossman C, Hernandez AF, Hinners JE, Hudson L, Kennedy A, Marchisotto MJ, Myers E, Nowell WB, Nosek BA, Sherer T, Shore C, Sim I, Smolensky L, Williams C, Wood J, Terry SF, Matrisian L. PMID: 33779573; PMCID: PMC8088851.
        View in: PubMed   Mentions:
      22. COVID-19 trials: declarations of data sharing intentions at trial registration and at publication. Trials. 2021 Feb 18; 22(1):153. Li R, von Isenburg M, Levenstein M, Neumann S, Wood J, Sim I. PMID: 33602275; PMCID: PMC7891481.
        View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
      23. Digital Medicine Community Perspectives and Challenges: Survey Study. JMIR Mhealth Uhealth. 2021 02 03; 9(2):e24570. Bent B, Sim I, Dunn JP. PMID: 33533721; PMCID: PMC7889423.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      24. Timely access to trial data in the context of a pandemic: the time is now. BMJ Open. 2020 10 29; 10(10):e039326. Li R, Wood J, Baskaran A, Neumann S, Graham E, Levenstein M, Sim I. PMID: 33122319; PMCID: PMC7597502.
        View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
      25. Ethical Framework for Assessing Manual and Digital Contact Tracing for COVID-19. Ann Intern Med. 2021 03; 174(3):395-400. Lo B, Sim I. PMID: 33076694; PMCID: PMC7573931.
        View in: PubMed   Mentions: 16     Fields:    Translation:HumansPHPublic Health
      26. Chia, a large annotated corpus of clinical trial eligibility criteria. Sci Data. 2020 08 27; 7(1):281. Kury F, Butler A, Yuan C, Fu LH, Sun Y, Liu H, Sim I, Carini S, Weng C. PMID: 32855408; PMCID: PMC7452886.
        View in: PubMed   Mentions: 10     Fields:    Translation:Humans
      27. The digital biomarker discovery pipeline: An open-source software platform for the development of digital biomarkers using mHealth and wearables data. J Clin Transl Sci. 2020 Jul 14; 5(1):e19. Bent B, Wang K, Grzesiak E, Jiang C, Qi Y, Jiang Y, Cho P, Zingler K, Ogbeide FI, Zhao A, Runge R, Sim I, Dunn J. PMID: 33948242; PMCID: PMC8057397.
        View in: PubMed   Mentions: 18  
      28. PERSONAL: Feasibility Study Protocol for Placebo-Controlled, Randomized n-of-1 Trials of Tamsulosin for Lower Urinary Tract Symptoms. Front Digit Health. 2020; 2:7. Bauer SR, Breyer BN, Oni-Orisan A, Steinman MA, Sim I, McCulloch CE, Kenfield SA. PMID: 34713020; PMCID: PMC8521798.
        View in: PubMed   Mentions: 3  
      29. Feasibility, Acceptability, and Influence of mHealth-Supported N-of-1 Trials for Enhanced Cognitive and Emotional Well-Being in US Volunteers. Front Public Health. 2020; 8:260. Kravitz RL, Aguilera A, Chen EJ, Choi YK, Hekler E, Karr C, Kim KK, Phatak S, Sarkar S, Schueller SM, Sim I, Yang J, Schmid CH. PMID: 32695740; PMCID: PMC7336867.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      30. Data Sharing and Reuse. Principles and Practice of Clinical Trials. 2020 Jun 19; 1-22. Sim SI. .
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      31. Time for NIH to lead on data sharing. Science. 2020 03 20; 367(6484):1308-1309. Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R. PMID: 32193313.
        View in: PubMed   Mentions: 18     Fields:    
      32. Mobile Devices and Health. N Engl J Med. 2019 09 05; 381(10):956-968. Sim I. PMID: 31483966.
        View in: PubMed   Mentions: 136     Fields:    Translation:Humans
      33. How Clinical Trial Data Sharing Platforms Can Advance the Study of Biomarkers. J Law Med Ethics. 2019 09; 47(3):369-373. Li R, Sim I. PMID: 31560635.
        View in: PubMed   Mentions: 2     Fields:    Translation:Humans
      34. Effect of Mobile Device-Assisted N-of-1 Trial Participation on Analgesic Prescribing for Chronic Pain: Randomized Controlled Trial. J Gen Intern Med. 2020 01; 35(1):102-111. Odineal DD, Marois MT, Ward D, Schmid CH, Cabrera R, Sim I, Wang Y, Wilsey B, Duan N, Henry SG, Kravitz RL. PMID: 31463686; PMCID: PMC6957655.
        View in: PubMed   Mentions: 7     Fields:    Translation:Humans
      35. Why we need a small data paradigm. BMC Med. 2019 07 17; 17(1):133. Hekler EB, Klasnja P, Chevance G, Golaszewski NM, Lewis D, Sim I. PMID: 31311528; PMCID: PMC6636023.
        View in: PubMed   Mentions: 33     Fields:    Translation:Humans
      36. A randomized trial provided new evidence on the accuracy and efficiency of traditional vs. electronically annotated abstraction approaches in systematic reviews. J Clin Epidemiol. 2019 11; 115:77-89. Li T, Saldanha IJ, Jap J, Smith BT, Canner J, Hutfless SM, Branch V, Carini S, Chan W, de Bruijn B, Wallace BC, Walsh SA, Whamond EJ, Murad MH, Sim I, Berlin JA, Lau J, Dickersin K, Schmid CH. PMID: 31302205.
        View in: PubMed   Mentions: 9     Fields:    Translation:Humans
      37. Role of Health Information Technology in Addressing Health Disparities: Patient, Clinician, and System Perspectives. Med Care. 2019 06; 57 Suppl 6 Suppl 2:S115-S120. Zhang X, Hailu B, Tabor DC, Gold R, Sayre MH, Sim I, Jean-Francois B, Casnoff CA, Cullen T, Thomas VA, Artiles L, Williams K, Le PT, Aklin CF, James R. PMID: 31095049; PMCID: PMC6589829.
        View in: PubMed   Mentions: 19     Fields:    Translation:Humans
      38. A Case for n-of-1 Trials-Reply. JAMA Intern Med. 2019 03 01; 179(3):453. Kravitz RL, Sim I, Duan N. PMID: 30830192.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      39. Finding Benefit in n-of-1 Trials-Reply. JAMA Intern Med. 2019 03 01; 179(3):455. Kravitz RL, Schmid CH, Sim I. PMID: 30830195.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      40. The Global academic research organization network: Data sharing to cure diseases and enable learning health systems. Learn Health Syst. 2019 Jan; 3(1):e10073. Fukushima M, Austin C, Sato N, Maruyama T, Navarro E, Rocca M, Demotes J, Haendel M, Volchenboum SL, Cowperthwaite M, Silverstein JC, Webb C, Sim I, Chase M, Speakman J, Augustine E, Ford DE, Kush R. PMID: 31245596; PMCID: PMC6508835.
        View in: PubMed   Mentions: 5  
      41. Moving Data Sharing Forward: The Launch of the Vivli Platform. NAM Perspectives. 2018 Nov 19; 8(11). Li LR, Scott SJ, Rockhold RF, Hill HN, Wood WJ, Sim SI. .
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      42. Patient Perceptions of Their Own Data in mHealth Technology-Enabled N-of-1 Trials for Chronic Pain: Qualitative Study. JMIR Mhealth Uhealth. 2018 Oct 11; 6(10):e10291. Whitney RL, Whitney RL, Ward DH, Marois MT, Schmid CH, Sim I, Kravitz RL. PMID: 30309834; PMCID: PMC6231865.
        View in: PubMed   Mentions: 13     Fields:    
      43. Effect of Mobile Device-Supported Single-Patient Multi-crossover Trials on Treatment of Chronic Musculoskeletal Pain: A Randomized Clinical Trial. JAMA Intern Med. 2018 10 01; 178(10):1368-1377. Kravitz RL, Schmid CH, Marois M, Wilsey B, Ward D, Hays RD, Duan N, Wang Y, MacDonald S, Jerant A, Servadio JL, Haddad D, Sim I. PMID: 30193253; PMCID: PMC6233756.
        View in: PubMed   Mentions: 24     Fields:    Translation:Humans
      44. Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K). IEEE Pervasive Comput. 2017 Apr-Jun; 16(2):18-22. Kumar S, Abowd G, Abraham WT, al'Absi M, Chau DHP, Ertin E, Estrin D, Ganesan D, Hnat T, Hossain SM, Ives Z, Kerr J, Marlin BM, Murphy S, Rehg JM, Nahum-Shani I, Shetty V, Sim I, Spring B, Srivastava M, Wetter D. PMID: 29276451; PMCID: PMC5739587.
        View in: PubMed   Mentions: 11  
      45. Evaluating Data Abstraction Assistant, a novel software application for data abstraction during systematic reviews: protocol for a randomized controlled trial. Syst Rev. 2016 11 22; 5(1):196. Saldanha IJ, Schmid CH, Lau J, Dickersin K, Berlin JA, Jap J, Smith BT, Carini S, Chan W, De Bruijn B, Wallace BC, Hutfless SM, Sim I, Murad MH, Walsh SA, Whamond EJ, Li T. PMID: 27876082; PMCID: PMC5120497.
        View in: PubMed   Mentions: 6     Fields:    Translation:Humans
      46. A Global, Neutral Platform for Sharing Trial Data. N Engl J Med. 2016 Jun 23; 374(25):2411-3. Bierer BE, Li R, Barnes M, Sim I. PMID: 27168194.
        View in: PubMed   Mentions: 46     Fields:    Translation:Humans
      47. Two Ways of Knowing: Big Data and Evidence-Based Medicine. Ann Intern Med. 2016 Apr 19; 164(8):562-3. Sim I. PMID: 26809201.
        View in: PubMed   Mentions: 18     Fields:    Translation:Humans
      48. Multivariate analysis of the population representativeness of related clinical studies. J Biomed Inform. 2016 Apr; 60:66-76. He Z, Ryan P, Hoxha J, Wang S, Carini S, Sim I, Weng C. PMID: 26820188; PMCID: PMC4837055.
        View in: PubMed   Mentions: 16     Fields:    Translation:Humans
      49. Informatics: Make sense of health data. Nature. 2015 Nov 05; 527(7576):31-2. Elliott JH, Grimshaw J, Altman R, Bero L, Goodman SN, Henry D, Macleod M, Tovey D, Tugwell P, White H, Sim I. PMID: 26536942.
        View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
      50. Center of excellence for mobile sensor data-to-knowledge (MD2K). J Am Med Inform Assoc. 2015 Nov; 22(6):1137-42. Kumar S, Abowd GD, Abraham WT, al'Absi M, Beck JG, Chau DH, Condie T, Conroy DE, Ertin E, Estrin D, Ganesan D, Lam C, Marlin B, Marsh CB, Murphy SA, Nahum-Shani I, Patrick K, Rehg JM, Sharmin M, Shetty V, Sim I, Spring B, Srivastava M, Wetter DW. PMID: 26555017; PMCID: PMC5009911.
        View in: PubMed   Mentions: 24     Fields:    Translation:Humans
      51. The PREEMPT study - evaluating smartphone-assisted n-of-1 trials in patients with chronic pain: study protocol for a randomized controlled trial. Trials. 2015 Feb 27; 16:67. Barr C, Marois M, Sim I, Schmid CH, Wilsey B, Ward D, Duan N, Hays RD, Selsky J, Servadio J, Schwartz M, Dsouza C, Dhammi N, Holt Z, Baquero V, MacDonald S, Jerant A, Sprinkle R, Kravitz RL. PMID: 25881274; PMCID: PMC4367894.
        View in: PubMed   Mentions: 17     Fields:    Translation:Humans
      52. Visual aggregate analysis of eligibility features of clinical trials. J Biomed Inform. 2015 Apr; 54:241-55. He Z, Carini S, Sim I, Weng C. PMID: 25615940; PMCID: PMC4408222.
        View in: PubMed   Mentions: 13     Fields:    Translation:Humans
      53. Towards Constructing a New Taxonomy for Psychiatry Using Self-reported Symptoms. Stud Health Technol Inform. 2015; 216:736-40. Ross J, Neylan T, Weiner M, Chao L, Samuelson K, Sim I. PMID: 26262149.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      54. A method for analyzing commonalities in clinical trial target populations. AMIA Annu Symp Proc. 2014; 2014:1777-86. He Z, Carini S, Hao T, Sim I, Weng C. PMID: 25954450; PMCID: PMC4419878.
        View in: PubMed   Mentions: 16     Fields:    Translation:Humans
      55. Patient-centered care, collaboration, communication, and coordination: a report from AMIA's 2013 Policy Meeting. J Am Med Inform Assoc. 2015 Apr; 22(e1):e2-6. Brennan PF, Valdez R, Alexander G, Arora S, Bernstam EV, Edmunds M, Kirienko N, Martin RD, Sim I, Skiba D, Rosenbloom T. PMID: 25359545.
        View in: PubMed   Mentions: 9     Fields:    Translation:Humans
      56. Academic Medical Centers as digital health catalysts. Healthc (Amst). 2014 Sep; 2(3):173-6. DePasse JW, Chen CE, Sawyer A, Jethwani K, Sim I. PMID: 26250503.
        View in: PubMed   Mentions: 19     Fields:    
      57. The Ontology of Clinical Research (OCRe): an informatics foundation for the science of clinical research. J Biomed Inform. 2014 Dec; 52:78-91. Sim I, Tu SW, Carini S, Lehmann HP, Pollock BH, Peleg M, Wittkowski KM. PMID: 24239612; PMCID: PMC4019723.
        View in: PubMed   Mentions: 26     Fields:    Translation:Humans
      58. Sponsorship and design characteristics of trials registered in Contemp Clin Trials. 2013 Mar; 34(2):348-55. Roumiantseva D, Carini S, Sim I, Wagner TH. PMID: 23380028.
        View in: PubMed   Mentions: 11     Fields:    Translation:Humans
      59. Deriving an abstraction network to support quality assurance in OCRe. AMIA Annu Symp Proc. 2012; 2012:681-9. Ochs C, Agrawal A, Perl Y, Halper M, Tu SW, Carini S, Sim I, Noy N, Musen M, Geller J. PMID: 23304341; PMCID: PMC3540580.
        View in: PubMed   Mentions: 11     Fields:    
      60. Ontology-based federated data access to human studies information. AMIA Annu Symp Proc. 2012; 2012:856-65. Sim I, Carini S, Tu SW, Detwiler LT, Brinkley J, Mollah SA, Burke K, Lehmann HP, Chakraborty S, Wittkowski KM, Pollock BH, Johnson TM, Huser V, Human Studies Database Project. PMID: 23304360; PMCID: PMC3540523.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      61. Making sense of mobile health data: an open architecture to improve individual- and population-level health. J Med Internet Res. 2012 Aug 09; 14(4):e112. Chen C, Haddad D, Selsky J, Hoffman JE, Kravitz RL, Estrin DE, Sim I. PMID: 22875563; PMCID: PMC3510692.
        View in: PubMed   Mentions: 39     Fields:    Translation:HumansPHPublic Health
      62. EliXR-TIME: A Temporal Knowledge Representation for Clinical Research Eligibility Criteria. AMIA Jt Summits Transl Sci Proc. 2012; 2012:71-80. Boland MR, Tu SW, Carini S, Sim I, Weng C. PMID: 22779055; PMCID: PMC3392056.
        View in: PubMed   Mentions: 18  
      63. Study Protocol Representation. Clinical Research Informatics. 2012 Jan 1; 155-174. Sim SI, Niland NJ. .
        View in: Publisher Site   Mentions:
      64. Information Technology research challenges for healthcare: from discovery to delivery. ACM SIGHIT Record. 2011 Mar 1; 1(1):4-9. Graham GS, Estrin ED, Horvitz HE, Kohane KI, Mynatt ME, Sim SI. .
        View in: Publisher Site   Mentions:
      65. Network analysis of clinical trials on depression: implications for comparative effectiveness research. AMIA Annu Symp Proc. 2010 Nov 13; 2010:51-5. Bhavnani SK, Carini S, Ross J, Sim I. PMID: 21346939; PMCID: PMC3041357.
        View in: PubMed   Mentions: 6     Fields:    Translation:Humans
      66. Health care delivery. Open mHealth architecture: an engine for health care innovation. Science. 2010 Nov 05; 330(6005):759-60. Estrin D, Sim I. PMID: 21051617.
        View in: PubMed   Mentions: 75     Fields:    Translation:Humans
      67. ExaCT: automatic extraction of clinical trial characteristics from journal publications. BMC Med Inform Decis Mak. 2010 Sep 28; 10:56. Kiritchenko S, de Bruijn B, Carini S, Martin J, Sim I. PMID: 20920176; PMCID: PMC2954855.
        View in: PubMed   Mentions: 44     Fields:    Translation:Humans
      68. A practical method for transforming free-text eligibility criteria into computable criteria. J Biomed Inform. 2011 Apr; 44(2):239-50. Tu SW, Peleg M, Carini S, Bobak M, Ross J, Rubin D, Sim I. PMID: 20851207; PMCID: PMC3129371.
        View in: PubMed   Mentions: 63     Fields:    
      69. Analysis of eligibility criteria complexity in clinical trials. Summit Transl Bioinform. 2010 Mar 01; 2010:46-50. Ross J, Tu S, Carini S, Sim I. PMID: 21347148; PMCID: PMC3041539.
        View in: PubMed   Mentions: 54  
      70. Ontology mapping and data discovery for the translational investigator. Summit Transl Bioinform. 2010 Mar 01; 2010:66-70. Wynden R, Weiner MG, Sim I, Gabriel D, Casale M, Carini S, Hastings S, Ervin D, Tu S, Gennari JH, Anderson N, Mobed K, Lakshminarayanan P, Massary M, Cucina RJ. PMID: 21347152; PMCID: PMC3041530.
        View in: PubMed   Mentions: 4  
      71. The human studies database project: federating human studies design data using the ontology of clinical research. Summit Transl Bioinform. 2010 Mar 01; 2010:51-5. Sim I, Carini S, Tu S, Wynden R, Pollock BH, Mollah SA, Gabriel D, Hagler HK, Scheuermann RH, Lehmann HP, Wittkowski KM, Nahm M, Bakken S. PMID: 21347149; PMCID: PMC3041546.
        View in: PubMed   Mentions: 18  
      72. Formal representation of eligibility criteria: a literature review. J Biomed Inform. 2010 Jun; 43(3):451-67. Weng C, Tu SW, Sim I, Richesson R. PMID: 20034594; PMCID: PMC2878905.
        View in: PubMed   Mentions: 81     Fields:    Translation:Humans
      73. Development and evaluation of a study design typology for human research. AMIA Annu Symp Proc. 2009 Nov 14; 2009:81-5. Carini S, Pollock BH, Lehmann HP, Bakken S, Barbour EM, Gabriel D, Hagler HK, Harper CR, Mollah SA, Nahm M, Nguyen HH, Scheuermann RH, Sim I. PMID: 20351827; PMCID: PMC2815479.
        View in: PubMed   Mentions: 7     Fields:    Translation:Humans
      74. Compliance of clinical trial registries with the World Health Organization minimum data set: a survey. Trials. 2009 Jul 22; 10:56. Moja LP, Moschetti I, Nurbhai M, Compagnoni A, Liberati A, Grimshaw JM, Chan AW, Dickersin K, Krleza-Jeric K, Moher D, Sim I, Volmink J. PMID: 19624821; PMCID: PMC2734552.
        View in: PubMed   Mentions: 38     Fields:    Translation:Humans
      75. Synergies and distinctions between computational disciplines in biomedical research: perspective from the Clinical andTranslational Science Award programs. Acad Med. 2009 Jul; 84(7):964-70. Bernstam EV, Hersh WR, Johnson SB, Chute CG, Nguyen H, Sim I, Nahm M, Weiner MG, Miller P, DiLaura RP, Overcash M, Lehmann HP, Eichmann D, Athey BD, Scheuermann RH, Anderson N, Starren J, Harris PA, Smith JW, Barbour E, Silverstein JC, Krusch DA, Nagarajan R, Becich MJ, CTSA Biomedical Informatics Key Function Committee. PMID: 19550198; PMCID: PMC2884382.
        View in: PubMed   Mentions: 18     Fields:    Translation:Humans
      76. Unintended consequences of health information technology: a need for biomedical informatics. J Biomed Inform. 2010 Oct; 43(5):828-30. Bernstam EV, Hersh WR, Sim I, Eichmann D, Silverstein JC, Smith JW, Becich MJ. PMID: 19508898; PMCID: PMC2891863.
        View in: PubMed   Mentions: 4     Fields:    Translation:Humans
      77. Keeping raw data in context. Science. 2009 Feb 06; 323(5915):713. Sim I, Chute CG, Lehmann H, Nagarajan R, Nahm M, Scheuermann RH. PMID: 19197039.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      78. Changes to NIH grant system may backfire. Science. 2008 Nov 21; 322(5905):1187-8. Karp PD, Sherlock G, Gerlt JA, Sim I, Paulsen I, Babbitt PC, Laderoute K, Hunter L, Sternberg P, Wooley J, Bourne PE. PMID: 19023064.
        View in: PubMed   Mentions:    Fields:    
      79. Characterizing primary care research: PCROM versus BRIDG. AMIA Annu Symp Proc. 2008 Nov 06; 1145. Speedie SM, Taweel A, Sim I, Arvanitis TN, Arvanitis T, Delaney B, Peterson KA. PMID: 18998919.
        View in: PubMed   Mentions:    Fields:    
      80. An interactive tool for visualizing design heterogeneity in clinical trials. AMIA Annu Symp Proc. 2008 Nov 06; 298-302. Hernandez ME, Carini S, Storey MA, Sim I. PMID: 18998925; PMCID: PMC2656051.
        View in: PubMed   Mentions: 4     Fields:    
      81. Automated information extraction of key trial design elements from clinical trial publications. AMIA Annu Symp Proc. 2008 Nov 06; 141-5. de Bruijn B, Carini S, Kiritchenko S, Martin J, Sim I. PMID: 18999067; PMCID: PMC2655966.
        View in: PubMed   Mentions: 22     Fields:    
      82. Publication of clinical trials supporting successful new drug applications: a literature analysis. PLoS Med. 2008 Sep 23; 5(9):e191. Lee K, Bacchetti P, Sim I. PMID: 18816163; PMCID: PMC2553819.
        View in: PubMed   Mentions: 70     Fields:    Translation:Humans
      83. The Primary Care Research Object Model (PCROM): a computable information model for practice-based primary care research. J Am Med Inform Assoc. 2008 Sep-Oct; 15(5):661-70. Speedie SM, Taweel A, Sim I, Arvanitis TN, Delaney B, Peterson KA. PMID: 18579829; PMCID: PMC2528032.
        View in: PubMed   Mentions: 6     Fields:    Translation:Humans
      84. Reporting the findings of clinical trials: a discussion paper. Bull World Health Organ. 2008 Jun; 86(6):492-3. Ghersi D, Clarke M, Berlin J, Gülmezoglu A, Kush R, Lumbiganon P, Moher D, Rockhold F, Sim I, Wager E. PMID: 18568282; PMCID: PMC2647457.
        View in: PubMed   Mentions: 15     Fields:    Translation:Humans
      85. Trial registration for public trust: making the case for medical devices. J Gen Intern Med. 2008 Jan; 23 Suppl 1:64-8. Sim I. PMID: 18095047; PMCID: PMC2150638.
        View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
      86. [Principles of the international registry of protocols and clinical trial results based on health interventions in human beings: Ottawa Declaration (part 1)]. Rev Panam Salud Publica. 2006 Jun; 19(6):413-6. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C, en nombre del grupo de Ottawa. PMID: 16968596.
        View in: PubMed   Mentions:    Fields:    Translation:Humans
      87. Clinical trial registration: transparency is the watchword. Lancet. 2006 May 20; 367(9523):1631-3. Sim I, Chan AW, Gülmezoglu AM, Evans T, Pang T. PMID: 16714166.
        View in: PubMed   Mentions: 54     Fields:    Translation:Humans
      88. Assessing clinical trial results. Science. 2006 Apr 21; 312(5772):365-6; author reply 365-6. Chan AW, Sim I, Gülmezoglu AM, Unterlerchner P, Karam G, Pang T. PMID: 16634140.
        View in: PubMed   Mentions:    Fields:    Translation:Humans
      89. International clinical trial registration: any progress? Wien Klin Wochenschr. 2006 Feb; 118(1-2):1-2. Gülmezoglu AM, Sim I. PMID: 16489516.
        View in: PubMed   Mentions: 1     Fields:    
      90. A taxonomic description of computer-based clinical decision support systems. J Biomed Inform. 2006 Dec; 39(6):656-67. Berlin A, Sorani M, Sim I. PMID: 16442854.
        View in: PubMed   Mentions: 32     Fields:    Translation:Humans
      91. National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge. OMICS. 2006; 10(2):185-98. Rubin DL, Lewis SE, Mungall CJ, Misra S, Westerfield M, Ashburner M, Sim I, Chute CG, Solbrig H, Storey MA, Smith B, Day-Richter J, Noy NF, Musen MA. PMID: 16901225.
        View in: PubMed   Mentions: 46     Fields:    
      92. RuleEd, a web-based semantic network interface for constructing and revising computable eligibility rules. AMIA Annu Symp Proc. 2006; 1051. Olasov B, Sim I. PMID: 17238670; PMCID: PMC1839587.
        View in: PubMed   Mentions: 4     Fields:    
      93. Beyond trial registration: a global trial bank for clinical trial reporting. PLoS Med. 2005 Nov; 2(11):e365. Sim I, Detmer DE. PMID: 16220999; PMCID: PMC1255763.
        View in: PubMed   Mentions: 19     Fields:    Translation:Humans
      94. The value of electronic health records in solo or small group practices. Health Aff (Millwood). 2005 Sep-Oct; 24(5):1127-37. Miller RH, West C, Brown TM, Sim I, Ganchoff C. PMID: 16162555.
        View in: PubMed   Mentions: 52     Fields:    Translation:Humans
      95. Principles for international registration of protocol information and results from human trials of health related interventions: Ottawa statement (part 1). BMJ. 2005 Apr 23; 330(7497):956-8. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C. PMID: 15845980; PMCID: PMC556346.
        View in: PubMed   Mentions: 72     Fields:    Translation:Humans
      96. Quantifying the gap between proof and practice. Evid Based Cardiovasc Med. 2004 Dec; 8(4):287-90. Sim I, Cummings SR. PMID: 16379955.
        View in: PubMed   Mentions:    Fields:    
      97. An ontology of randomized controlled trials for evidence-based practice: content specification and evaluation using the competency decomposition method. J Biomed Inform. 2004 Apr; 37(2):108-19. Sim I, Olasov B, Carini S. PMID: 15120657.
        View in: PubMed   Mentions: 23     Fields:    
      98. Physicians' use of electronic medical records: barriers and solutions. Health Aff (Millwood). 2004 Mar-Apr; 23(2):116-26. Miller RH, Sim I. PMID: 15046136.
        View in: PubMed   Mentions: 213     Fields:    Translation:Humans
      99. EyePACS: an open source clinical communication system for eye care. Stud Health Technol Inform. 2004; 107(Pt 1):207-11. Cuadros J, Sim I. PMID: 15360804.
        View in: PubMed   Mentions: 4     Fields:    Translation:Humans
      100. Electronic medical records in solo/small groups: a qualitative study of physician user types. Stud Health Technol Inform. 2004; 107(Pt 1):658-62. Miller RH, Sim I, Newman J. PMID: 15360895.
        View in: PubMed   Mentions: 6     Fields:    Translation:Humans
      101. Trial bank publishing: phase I results. Stud Health Technol Inform. 2004; 107(Pt 2):1476-80. Sim I, Carini S, Olasov B, Jeng S. PMID: 15361060.
        View in: PubMed   Mentions: 2     Fields:    
      102. Characteristics of outpatient clinical decision support systems: a taxonomic description. Stud Health Technol Inform. 2004; 107(Pt 1):578-81. Berlin A, Sorani M, Sim I. PMID: 15360878.
        View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      103. A new framework for describing and quantifying the gap between proof and practice. Med Care. 2003 Aug; 41(8):874-81. Sim I, Cummings SR. PMID: 12886168.
        View in: PubMed   Mentions:    Fields:    Translation:Humans
      104. A framework for classifying decision support systems. AMIA Annu Symp Proc. 2003; 599-603. Sim I, Berlin A. PMID: 14728243; PMCID: PMC1480261.
        View in: PubMed   Mentions: 6     Fields:    
      105. SysBank: a knowledge base for systematic reviews of randomized clinical trials. AMIA Annu Symp Proc. 2003; 804. Carini S, Sim I. PMID: 14728309; PMCID: PMC1479927.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      106. The Trial Bank system: capturing randomized trials for evidence-based medicine. AMIA Annu Symp Proc. 2003; 1076. Sim I, Olasov B, Carini S. PMID: 14728579; PMCID: PMC1479965.
        View in: PubMed   Mentions: 6     Fields:    Translation:Humans
      107. Antibiotic treatment of acute bronchitis in smokers: a systematic review. J Gen Intern Med. 2002 Mar; 17(3):230-4. Linder JA, Sim I. PMID: 11929510; PMCID: PMC1495016.
        View in: PubMed   Mentions: 9     Fields:    Translation:Humans
      108. Electronic trial banks: a complementary method for reporting randomized trials. Med Decis Making. 2000 Oct-Dec; 20(4):440-50. Sim I, Owens DK, Lavori PW, Rennels GD. PMID: 11059477.
        View in: PubMed   Mentions: 15     Fields:    Translation:Humans
      109. Meta-analyses and large randomized, controlled trials. N Engl J Med. 1998 Jan 01; 338(1):61; author reply 61-2. Sim I, Lavori P. PMID: 9424568.
        View in: PubMed   Mentions:    Fields:    
      110. Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death. Circulation. 1997 Nov 04; 96(9):2823-9. Sim I, McDonald KM, Lavori PW, Norbutas CM, Hlatky MA. PMID: 9386144.
        View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
      111. Growing pains of meta-analysis. BMJ. 1996 Sep 21; 313(7059):702-3. Sim I, Hlatky MA. PMID: 8819428; PMCID: PMC2352128.
        View in: PubMed   Mentions: 3     Fields:    
      112. S12 Standardized computer-based reporting of clinical trials: In support of meta-analysis. Contemporary Clinical Trials. 1996 Apr 1; 17(2):s44. Sim SI. .
        View in: Publisher Site   Mentions:
      113. A meta-analysis of randomized trials comparing coronary artery bypass grafting with percutaneous transluminal coronary angioplasty in multivessel coronary artery disease. Am J Cardiol. 1995 Nov 15; 76(14):1025-9. Sim I, Gupta M, McDonald K, Bourassa MG, Hlatky MA. PMID: 7484855.
        View in: PubMed   Mentions: 5     Fields:    Translation:Humans
      114. A trial bank model for the publication of clinical trials. Proc Annu Symp Comput Appl Med Care. 1995; 863-7. Sim I, Rennels G. PMID: 8563415; PMCID: PMC2579216.
        View in: PubMed   Mentions: 3     Fields:    Translation:Humans
      115. Physician's information customizer (PIC): using a shareable user model to filter the medical literature. Medinfo. 1995; 8 Pt 2:1447-51. Pratt W, Sim I. PMID: 8591472.
        View in: PubMed   Mentions: 1     Fields:    
      116. The NGF complex from the African rat Mastomys natalensis. Neurochem Res. 1991 Jun; 16(6):603-12. Burcham TS, Sim I, Bolin LM, Shooter EM. PMID: 1791910.
        View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
      117. Synthesis and antiviral activity of metabolites of rimantadine. J Med Chem. 1990 Jul; 33(7):1992-5. Manchand PS, Cerruti RL, Martin JA, Hill CH, Merrett JH, Keech E, Belshe RB, Connell EV, Sim IS. PMID: 2362279.
        View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
      118. Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. Int J Hyperthermia. 1987 Mar-Apr; 3(2):123-32. Lepock JR, Cheng KH, Al-Qysi H, Sim I, Koch CJ, Kruuv J. PMID: 3036971.
        View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
      119. Estrous cycle variations in cholecystokinin and substance P concentrations in discrete areas of the rat brain. Neuroendocrinology. 1986; 42(3):226-31. Frankfurt M, Siegel RA, Sim I, Wuttke W. PMID: 2419781.
        View in: PubMed   Mentions: 5     Fields:    Translation:Animals
      120. Cholecystokinin and substance P concentrations in discrete areas of the rat brain: sex differences. Brain Res. 1985 Dec 09; 358(1-2):53-8. Frankfurt M, Siegel RA, Sim I, Wuttke W. PMID: 2416392.
        View in: PubMed   Mentions: 6     Fields:    Translation:Animals