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Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19. Sci Rep. 2021 Jun 10; 11(1):12310.
Le BL, Andreoletti G, Oskotsky T, Vallejo-Gracia A, Rosales R, Yu K, Kosti I, Leon KE, Bunis DG, Li C, Kumar GR, White KM, García-Sastre A, Ott M, Sirota M. PMID: 34112877.
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Translation:
HumansCells
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Drugs in COVID-19 Clinical Trials: Predicting Transporter-Mediated Drug-Drug Interactions Using In Vitro Assays and Real-World Data. Clin Pharmacol Ther. 2021 07; 110(1):108-122.
Yee SW, Vora B, Oskotsky T, Zou L, Jakobsen S, Enogieru OJ, Koleske ML, Kosti I, Rödin M, Sirota M, Giacomini KM. PMID: 33759449.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19. Res Sq. 2021 Mar 30.
Le BL, Andreoletti G, Oskotsky T, Vallejo-Gracia A, Rosales R, Yu K, Kosti I, Leon KE, Bunis DG, Li C, Kumar GR, White KM, García-Sastre A, Ott M, Sirota M. PMID: 33821262.
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PubMed Mentions:
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Decreased Mortality Rate Among COVID-19 Patients Prescribed Statins: Data From Electronic Health Records in the US. Front Med (Lausanne). 2021; 8:639804.
Maric I, Oskotsky T, Kosti I, Le B, Wong RJ, Shaw GM, Sirota M, Stevenson DK. PMID: 33614688.
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PubMed Mentions:
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Data Integration for Immunology. Annual Review of Biomedical Data Science. 2020 Jul 20; 3(1):1-24.
Silvia Pineda, Daniel G. Bunis, Idit Kosti, Marina Sirota. .
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Meta-Analysis of Vaginal Microbiome Data Provides New Insights Into Preterm Birth. Front Microbiol. 2020; 11:476.
Kosti I, Lyalina S, Pollard KS, Butte AJ, Sirota M. PMID: 32322240.
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PubMed Mentions:
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Electronic Medical Records Enable Precision Medicine Approaches for Celiac Disease. J Pediatr Gastroenterol Nutr. 2018 10; 67(4):434-435.
Kosti I, Sirota M. PMID: 29746345.
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PubMed Mentions: Fields:
Translation:
Humans
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Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. Front Immunol. 2018; 9:993.
Vora B, Wang A, Kosti I, Huang H, Paranjpe I, Woodruff TJ, MacKenzie T, Sirota M. PMID: 29867970.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma. EBioMedicine. 2018 Jan; 27:167-175.
Sharpnack MF, Chen B, Aran D, Kosti I, Sharpnack DD, Carbone DP, Mallick P, Huang K. PMID: 29273356.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):E1375-E1384.
Volodin A, Kosti I, Goldberg AL, Cohen S. PMID: 28096335.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Cross-tissue Analysis of Gene and Protein Expression in Normal and Cancer Tissues. Sci Rep. 2016 05 04; 6:24799.
Kosti I, Jain N, Aran D, Butte AJ, Sirota M. PMID: 27142790.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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A diverse epigenetic landscape at human exons with implication for expression. Nucleic Acids Res. 2015 Apr 20; 43(7):3498-508.
Singer M, Kosti I, Pachter L, Mandel-Gutfreund Y. PMID: 25765649.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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RBPmap: a web server for mapping binding sites of RNA-binding proteins. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W361-7.
Paz I, Kosti I, Ares M, Cline M, Mandel-Gutfreund Y. PMID: 24829458.
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PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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The hnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life cycle stages of the parasite and regulates splicing and mRNA stability. Nucleic Acids Res. 2013 Jul; 41(13):6577-94.
Gupta SK, Kosti I, Plaut G, Pivko A, Tkacz ID, Cohen-Chalamish S, Biswas DK, Wachtel C, Waldman Ben-Asher H, Carmi S, Glaser F, Mandel-Gutfreund Y, Michaeli S. PMID: 23666624.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Trichoderma genomes: a vast reservoir of potential elicitor proteins. Trichoderma: biology and applications. 2013 Jan 1; 195-208.
B. A. Horwitz, I. Kosti, F. Glaser, M Mala. .
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Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi. PLoS Pathog. 2012; 8(12):e1003037.
Ohm RA, Feau N, Henrissat B, Schoch CL, Horwitz BA, Barry KW, Condon BJ, Copeland AC, Dhillon B, Glaser F, Hesse CN, Kosti I, LaButti K, Lindquist EA, Lucas S, Salamov AA, Bradshaw RE, Ciuffetti L, Hamelin RC, Kema GH, Lawrence C, Scott JA, Spatafora JW, Turgeon BG, de Wit PJ, Zhong S, Goodwin SB, Grigoriev IV. PMID: 23236275.
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PubMed Mentions:
183 Fields:
Translation:
AnimalsCells
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Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. mBio. 2012; 3(5):e00259-12.
Martinez DA, Oliver BG, Gräser Y, Goldberg JM, Li W, Martinez-Rossi NM, Monod M, Shelest E, Barton RC, Birch E, Brakhage AA, Chen Z, Gurr SJ, Heiman D, Heitman J, Kosti I, Rossi A, Saif S, Samalova M, Saunders CW, Shea T, Summerbell RC, Xu J, Young S, Zeng Q, Birren BW, Cuomo CA, White TC. PMID: 22951933.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimals
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An integrated regulatory network reveals pervasive cross-regulation among transcription and splicing factors. PLoS Comput Biol. 2012; 8(7):e1002603.
Kosti I, Radivojac P, Mandel-Gutfreund Y. PMID: 22844237.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Characterization of coding synonymous and non-synonymous variants in ADAMTS13 using ex vivo and in silico approaches. PLoS One. 2012; 7(6):e38864.
Edwards NC, Hing ZA, Perry A, Blaisdell A, Kopelman DB, Fathke R, Plum W, Newell J, Allen CE, S G, Shapiro A, Okunji C, Kosti I, Shomron N, Grigoryan V, Przytycka TM, Sauna ZE, Salari R, Mandel-Gutfreund Y, Komar AA, Kimchi-Sarfaty C. PMID: 22768050.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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ARTS, the unusual septin: structural and functional aspects. Biol Chem. 2011 Aug; 392(8-9):783-90.
Mandel-Gutfreund Y, Kosti I, Larisch S. PMID: 21824006.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. Genome Biol. 2011; 12(4):R40.
Kubicek CP, Herrera-Estrella A, Seidl-Seiboth V, Martinez DA, Druzhinina IS, Thon M, Zeilinger S, Casas-Flores S, Horwitz BA, Mukherjee PK, Mukherjee M, Kredics L, Alcaraz LD, Aerts A, Antal Z, Atanasova L, Cervantes-Badillo MG, Challacombe J, Chertkov O, McCluskey K, Coulpier F, Deshpande N, von Döhren H, Ebbole DJ, Esquivel-Naranjo EU, Fekete E, Flipphi M, Glaser F, Gómez-Rodríguez EY, Gruber S, Han C, Henrissat B, Hermosa R, Hernández-Oñate M, Karaffa L, Kosti I, Le Crom S, Lindquist E, Lucas S, Lübeck M, Lübeck PS, Margeot A, Metz B, Misra M, Nevalainen H, Omann M, Packer N, Perrone G, Uresti-Rivera EE, Salamov A, Schmoll M, Seiboth B, Shapiro H, Sukno S, Tamayo-Ramos JA, Tisch D, Wiest A, Wilkinson HH, Zhang M, Coutinho PM, Kenerley CM, Monte E, Baker SE, Grigoriev IV. PMID: 21501500.
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PubMed Mentions:
164 Fields:
Translation:
AnimalsCellsPHPublic Health
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SFmap: a web server for motif analysis and prediction of splicing factor binding sites. Nucleic Acids Res. 2010 Jul; 38(Web Server issue):W281-5.
Paz I, Akerman M, Dror I, Kosti I, Mandel-Gutfreund Y. PMID: 20501600.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Comparative analysis of fungal protein kinases and associated domains. BMC Genomics. 2010 Feb 24; 11:133.
Kosti I, Mandel-Gutfreund Y, Glaser F, Horwitz BA. PMID: 20178650.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells