Irene Acerbi, PhD

Title(s)Business Operations Manager, Surgery
SchoolSchool of Medicine
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    Irene Acerbi, Ph.D. is a biomedical engineer by training. After receving her B.sc. at the Polytechnic of Milano, Italy, she started her graduate training at Unit of Biophysics and Bioengineering (UBB) at the University of Barcelona, Spain, where she learned the nanotechniques of atomic force microscopy (AFM). Subsequently, Dr. Acerbi became a joint doctoral student with the UBB of the School of Medicine of the University of Barcelona and the Bioengineering Department at the Polytechnic University of Milano. After obtaining her Ph.D. in Bioengineering, she joined the Center for Bioengineering and Tissue Regeneration at University of California, San Francisco as a postdoctoral researcher in September 2010, and successfully applied the AFM technique on human breast tissue from prophylaxis mastectomy, pre-cancerous lesions, and invasive tumors. Dr. Acerbi's current research project is to identify high-risk populations for developing malignancy so that individuals can benefit from improved monitoring and treatment, sponsored by a three-year Post Doctoral Fellowship by Susan G. Komen Foundation.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nat Mater. 2020 Nov 30. Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. PMID: 33257795.
      View in: PubMed   Mentions:    Fields:    
    2. Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. J Clin Invest. 2020 11 02; 130(11):5721-5737. Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. PMID: 32721948.
      View in: PubMed   Mentions:    Fields:    
    3. Fitbit Usage in Patients With Breast Cancer Undergoing Chemotherapy. Clin Breast Cancer. 2019 12; 19(6):443-449.e1. Dreher N, Hadeler EK, Hartman SJ, Wong EC, Acerbi I, Rugo HS, Majure MC, Chien AJ, Esserman LJ, Melisko ME. PMID: 31285177.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. A breast cancer risk model as a predictor of interval cancer rate and tumor characteristics. Journal of Clinical Oncology. 2018 May 20; 36(15_suppl):1506-1506. Nickolas Dreher, Irene Acerbi, Edward Kenji Hadeler, Yiwey Shieh, Michelle E. Melisko, Athena Investigators and Advocates, Laura Esserman, Laura van 't Veer. .
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    5. Objective assessment of physical activity during chemotherapy for breast cancer. Journal of Clinical Oncology. 2017 May 20; 35(15_suppl):tps6626-tps6626. Michelle E. Melisko, Edward Kenji Hadeler, Sandahl H Nelson, Audrey Lunde, Irene Acerbi, Hope S. Rugo, Melanie Catherine Majure, Amy Jo Chien, Laura Esserman, Sheri J. Hartman. .
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    6. Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. Integr Biol (Camb). 2015 Oct; 7(10):1120-34. PMID: 25959051.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansCells
    7. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nat Med. 2014 Apr; 20(4):360-7. PMID: 24633304.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    8. Advocacy spurs innovation: promoting synergy between physical and biomedical sciences. EPJ Nonlinear Biomedical Physics. 2013 Dec 1; 1(1):1. Susan Samson, Irene Acerbi, Carole Baas, Valerie Weaver, Hope Rugo. .
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    9. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-ß-deficient mouse mammary carcinomas. Cancer Res. 2013 Sep 01; 73(17):5336-46. PMID: 23856251.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    10. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10. PMID: 23843613.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    11. Advocacy spurs innovation: promoting synergy between physical and biomedical sciences. EPJ Nonlinear Biomedical Physics. 2013; 1(1):1-13. Susan Samson, Irene Acerbi, Carole Baas, Valerie Weaver and Hope Rugo. View Publication.
    12. Ionizing Radiation Modifies Tissue Tension, Mechanosignaling, and Apoptosis in Human Breast. International Journal of Radiation Oncology • Biology • Physics. 2012 Nov 1; 84(3):s669. S. Zheng, I. Acerbi, N.Z. Kuhn, A. Au, C.C. Park, V.M. Weaver. .
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    13. 377 Extra-cellular Matrix Stiffness and Immune Cells Infiltrate Are Associated With Breast Tumor Phenotype. European Journal of Cancer. 2012 Jul 1; 48:s91. I. Acerbi, S.Y. Zheng, B. Ruffell, A. Au, Q. Shi, J.T. Liphardt, L.M. Coussens, Y.Y. Chen, E.S. Hwang, V.M. Weaver. .
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    14. 159 The Role of the Biophysical Properties of the Glycocalyx and Extracellular Matrix Tension in Enhancing Glioma Cell Invasion. European Journal of Cancer. 2012 Jul 1; 48:s38-s39. Y.A. Miroshnikova, I. Acerbi, S. Ilkhanizadeh, M.J. Paszek, A. Persson, V.M. Weaver. .
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    15. Integrin-specific mechanoresponses to compression and extension probed by cylindrical flat-ended AFM tips in lung cells. PLoS One. 2012; 7(2):e32261. PMID: 22384196.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Respiratory impedance during weaning from mechanical ventilation in a mixed population of critically ill patients. Br J Anaesth. 2009 Dec; 103(6):828-32. Sellares J, Acerbi I, Loureiro H, Dellaca RL, Ferrer M, Torres A, Navajas D, Farre R. PMID: 19887532.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Obstructive apneas induce early release of mesenchymal stem cells into circulating blood. Sleep. 2009 Jan; 32(1):117-9. Carreras A, Almendros I, Acerbi I, Montserrat JM, Navajas D, Farré R. PMID: 19189787.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    18. Continuous positive airway pressure (CPAP) induces early nasal inflammation. Sleep. 2008 Jan; 31(1):127-31. Almendros I, Acerbi I, Vilaseca I, Montserrat JM, Navajas D, Farré R. PMID: 18220086.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. Upper-airway inflammation triggered by vibration in a rat model of snoring. Sleep. 2007 Feb; 30(2):225-7. Almendros I, Acerbi I, Puig F, Montserrat JM, Navajas D, Farré R. PMID: 17326549.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
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