Irene Acerbi, PhD

Title(s)Program Manager, Surgery
SchoolSchool of Medicine
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    Irene Acerbi, Ph.D. is a biomedical engineer by training. After receving her B.sc. at the Polytechnic of Milano, Italy, she started her graduate training at Unit of Biophysics and Bioengineering (UBB) at the University of Barcelona, Spain, where she learned the nanotechniques of atomic force microscopy (AFM). Subsequently, Dr. Acerbi became a joint doctoral student with the UBB of the School of Medicine of the University of Barcelona and the Bioengineering Department at the Polytechnic University of Milano. After obtaining her Ph.D. in Bioengineering, she joined the Center for Bioengineering and Tissue Regeneration at University of California, San Francisco as a postdoctoral researcher in September 2010, and successfully applied the AFM technique on human breast tissue from prophylaxis mastectomy, pre-cancerous lesions, and invasive tumors. Dr. Acerbi's current research project is to identify high-risk populations for developing malignancy so that individuals can benefit from improved monitoring and treatment, sponsored by a three-year Post Doctoral Fellowship by Susan G. Komen Foundation.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Acerbi I, Cassereau L, Dean I, Shi Q, Au A, Park C, Chen YY, Liphardt J, Hwang ES, Weaver VM. Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. Integr Biol (Camb). 2015 Oct; 7(10):1120-34. PMID: 25959051; PMCID: PMC4593730.
    2. Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nat Med. 2014 Apr; 20(4):360-7. PMID: 24633304; PMCID: PMC3981899.
    3. Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-ß-deficient mouse mammary carcinomas. Cancer Res. 2013 Sep 01; 73(17):5336-46. PMID: 23856251; PMCID: PMC3766496.
    4. Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10. PMID: 23843613; PMCID: PMC3772386.
    5. Susan Samson, Irene Acerbi, Carole Baas, Valerie Weaver and Hope Rugo.Advocacy spurs innovation: promoting synergy between physical and biomedical sciences. EPJ Nonlinear Biomedical Physics. 2013; 1(1):1-13.
    6. Acerbi I, Luque T, Giménez A, Puig M, Reguart N, Farré R, Navajas D, Alcaraz J. Integrin-specific mechanoresponses to compression and extension probed by cylindrical flat-ended AFM tips in lung cells. PLoS One. 2012; 7(2):e32261. PMID: 22384196; PMCID: PMC3285695.
    7. Sellares J, Acerbi I, Loureiro H, Dellaca RL, Ferrer M, Torres A, Navajas D, Farre R. Respiratory impedance during weaning from mechanical ventilation in a mixed population of critically ill patients. Br J Anaesth. 2009 Dec; 103(6):828-32. PMID: 19887532.
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    8. Carreras A, Almendros I, Acerbi I, Montserrat JM, Navajas D, Farré R. Obstructive apneas induce early release of mesenchymal stem cells into circulating blood. Sleep. 2009 Jan; 32(1):117-9. PMID: 19189787; PMCID: PMC2625316.
    9. Almendros I, Acerbi I, Vilaseca I, Montserrat JM, Navajas D, Farré R. Continuous positive airway pressure (CPAP) induces early nasal inflammation. Sleep. 2008 Jan; 31(1):127-31. PMID: 18220086; PMCID: PMC2225550.
    10. Almendros I, Acerbi I, Puig F, Montserrat JM, Navajas D, Farré R. Upper-airway inflammation triggered by vibration in a rat model of snoring. Sleep. 2007 Feb; 30(2):225-7. PMID: 17326549.
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