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Iryna Lobach, PhD

Title(s)Associate Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Phone415-476-6115
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    Collapse Biography 
    Collapse Education and Training
    Texas A&M UniversityPhD2006Statistics
    Yale UniversityPostDoc in Statistical Genetics2008Public Health
    Collapse Awards and Honors
    The International Biometric Society2010Best Paper of the Year in Biometrics Journal

    Collapse Overview 
    Collapse Overview
    Dr. Iryna V. Lobach conducts research in applied statistics and supports the biostatistics component of biomedical research.

    Her methodological research interests are motivated by challenges arising in the analyses of how an effect of the genetic basis varies by non-genetic measures (environment), what is traditionally referred to as gene-environment interaction (GxE) analyses. This type of analyses might provide valuable clues to the underlying pathophysiologic mechanisms of complex phenotypes.

    For example, in collaboration with statisticians and biomedical researchers, Dr. Lobach developed an efficient retrospective analysis of case-control genetic studies in situations when the environmental variable is measured with error, e.g. diet or physical activity. Both in theory and in practice, this method improves efficiency of the risk parameter estimates and is capable of correcting coverage of 95% Confidence Intervals from e.g. 68% of the standard approach to the nominal 95% in a practical example of analyses of association between calcium intake and the risk of colorectal adenoma analyses.

    We developed statistical methods to incorporate heterogeneity of the clinical diagnosis characterized by biomarker studies in situations when 1) multiple distinct pathophysiologic mechanisms share symptoms and hence the clinical diagnosis; and 2) substantial segments of the population are undiagnosed. We show that the genetic variant will appear to interact with the environmental variable if the genetic variant affects the pathologically defined disease state and the environmental variable is related to the proportion of cases with that disease state. We then propose a pseudo-likelihood solution and apply the methods to large genome-wide studies of Prostate Cancer and Alzheimer’s disease.

    Recently, we developed case-only estimates of GxE in settings when 1) multiple disease state share the clinical diagnosis, 2) frequencies of the disease state of interest within the clinical diagnosis vary by the E or other variables, 3) both clinical diagnosis and the disease states are common. We show the application to Alzheimer's disease.

    We are also conducting studies to investigate bias in the genetic effect estimates due to omitting a continuous variable. Specifically, we are interested to assess what information is needed to correct the bias if the actual values of the continuous variable are not available to the researcher. For example, many of the genetic databases offer only a brief set of non-genetic variables. We show the application to Alzheimer's disease (https://www.biorxiv.org/content/10.1101/756015v1).

    We have recently studied whether a case-only study of GxE is better than a case-control study in the context when the disease state is common and when the multiple distinct disease states share a clinical diagnosis. We investigated differences in the GxE estimates in the context of Alzheimer's disease (https://www.biorxiv.org/content/10.1101/760322v1).

    Dr. Lobach supports the biostatistics component of multiple biomedical studies through collaboration, consultation (CTSI biostatistics consultant) and mentoring (K-grants, mentoring in the Training in Clinical Research Program).

    Collapse Research 
    Collapse Research Activities and Funding
    Role of the metabolic syndrome profile in genetic susceptibility to Alzheimer's d
    NIH R21AG043710May 15, 2014 - Apr 30, 2018
    Role: Principal Investigator
    Novel Analysis of Gene-Gene and Gene-Environment Interactions in Alcoholism
    NIH R21AA020356Sep 1, 2013 - Aug 31, 2017
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Post-lumpectomy breast calcifications: Can original tumor features assist in determining need for biopsy? Clin Imaging. 2021 Jan 20; 75:16-21. Greenwood HI, Kelil T, Lobach IV, Fong V, Price ER. PMID: 33486147.
      View in: PubMed   Mentions:    Fields:    
    2. Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia. Ann Neurol. 2021 Feb; 89(2):389-401. Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, Spina S, Grinberg LT, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 33219525.
      View in: PubMed   Mentions:    Fields:    
    3. A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease. Sci Transl Med. 2020 Aug 26; 12(558). Davis EJ, Broestl L, Abdulai-Saiku S, Worden K, Bonham LW, Miñones-Moyano E, Moreno AJ, Wang D, Chang K, Williams G, Garay BI, Lobach I, Devidze N, Kim D, Anderson-Bergman C, Yu GQ, White CC, Harris JA, Miller BL, Bennett DA, Arnold AP, De Jager PL, Palop JJ, Panning B, Yokoyama JS, Mucke L, Dubal DB. PMID: 32848093.
      View in: PubMed   Mentions: 1     Fields:    
    4. Pericardial Fat Enhancement: New Computed Tomography Biomarker Influences the Relationship Between Pericardial Fat and Coronary Artery Disease. J Thorac Imaging. 2020 Jul; 35(4):270-275. Kallianos KG, Lorca MC, Moraes GL, Devcic Z, Lobach I, Ordovas KG. PMID: 31913256.
      View in: PubMed   Mentions:    Fields:    
    5. Performance of screening MRI in high risk patients at initial versus subsequent screen. Clin Imaging. 2020 Oct; 66:87-92. PMID: 32460153.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Factors Predicting Metastatic Disease in 68Ga-PSMA-11 PET-Positive Osseous Lesions in Prostate Cancer. J Nucl Med. 2020 Dec; 61(12):1779-1785. Chiu LW, Lawhn-Heath C, Behr SC, Juarez R, Perez PM, Lobach I, Bucknor MD, Hope TA, Flavell RR. PMID: 32303599.
      View in: PubMed   Mentions: 1     Fields:    
    7. A systematic review and meta-analysis examining the effects of cannabis and its derivatives in adults with malignant CNS tumors. Neurooncol Pract. 2020 Jul; 7(4):376-383. PMID: 32765889.
      View in: PubMed   Mentions:
    8. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. 2020 05 06; 106(3):404-420.e8. Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, Chung BHY, Cogné B, Curry C, D'Agostino MD, Di Donato N, Faivre L, Héron D, Innes AM, Isidor B, Keren B, Kimball A, Klee EW, Kuentz P, Küry S, Martin-Coignard D, Mirzaa G, Mignot C, Miyake N, Matsumoto N, Fujita A, Nava C, Nizon M, Rodriguez D, Blok LS, Thauvin-Robinet C, Thevenon J, Vincent M, Ziegler A, Dobyns W, Richards LJ, Barkovich AJ, Floor SN, Silver DL, Sherr EH. PMID: 32135084.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Case-control versus case-only estimates of gene-environment interactions with common and misclassified clinical diagnosis. Genet Epidemiol. 2020 01; 44(1):4-15. Lobach I, Sheng Y, Lobach S, Zablotska L, Huang CY. PMID: 31667895.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer. Oncotarget. 2019 Oct 22; 10(58):6096-6110. Korenchan DE, Bok R, Sriram R, Liu K, Santos RD, Qin H, Lobach I, Korn N, Wilson DM, Kurhanewicz J, Flavell RR. PMID: 31692908.
      View in: PubMed   Mentions: 1     Fields:    
    11. A Simple Approximation to Bias in Gene-Environment Interaction Estimates When a Case Might Not Be the Case. Front Genet. 2019; 10:886. Lobach I, Kim I, Alekseyenko A, Lobach S, Zhang L. PMID: 31681402.
      View in: PubMed   Mentions:
    12. The impact of technical parameters on ablation volume during MR-guided focused ultrasound of desmoid tumors. Int J Hyperthermia. 2019; 36(1):473-476. Bucknor MD, Beroukhim G, Rieke V, Ozhinsky E, Lobach I. PMID: 30922118.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. A simple approximation to bias in the genetic effect estimates when multiple disease states share a clinical diagnosis. Genet Epidemiol. 2019 07; 43(5):522-531. Lobach I, Kim I, Alekseyenko A, Lobach S, Zhang L. PMID: 30888715.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. A simple approximation to the bias of gene-environment interactions in case-control studies with silent disease. Genet Epidemiol. 2019 04; 43(3):292-299. Lobach I, Sampson J, Lobach S, Alekseyenko A, Piryatinska A, He T, Zhang L. PMID: 30623487.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The Gambler's Fallacy in Screening Mammography. J Am Coll Radiol. 2019 Jun; 16(6):830-833. Callen AL, Lobach I, Mesina O, Marcus S, Joe BN, Sickles EA, Greenwood HI. PMID: 30611683.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Female XX sex chromosomes increase survival and extend lifespan in aging mice. Aging Cell. 2019 02; 18(1):e12871. Davis EJ, Lobach I, Dubal DB. PMID: 30560587.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    17. Bias in parameter estimates due to omitting gene-environment interaction terms in case-control studies. Genet Epidemiol. 2018 12; 42(8):838-845. Lobach I. PMID: 30302820.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Microcalcifications Detected at Screening Mammography: Synthetic Mammography and Digital Breast Tomosynthesis versus Digital Mammography. Radiology. 2018 12; 289(3):630-638. Lai YC, Ray KM, Lee AY, Hayward JH, Freimanis RI, Lobach IV, Joe BN. PMID: 30277445.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Case-control studies of gene-environment interactions. When a case might not be the case. PLoS One. 2018; 13(8):e0201140. Lobach I, Sampson J, Alekseyenko A, Lobach S, Zhang L. PMID: 30133451.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Gene-environment interactions in case-control studies with silent disease. Genet Epidemiol. 2018 09; 42(6):551-558. Lobach I, Sampson J, Lobach S, Zhang L. PMID: 29896809.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018 03 01; 75(3):342-352. Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, Yoon SJ, Rosen HJ, Grinberg L, Seeley WW, Miller BL, Jagust WJ, Gorno-Tempini ML. PMID: 29309493.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Synovial Fluid Profile at the Time of Anterior Cruciate Ligament Reconstruction and Its Association With Cartilage Matrix Composition 3 Years After Surgery. Am J Sports Med. 2018 03; 46(4):890-899. Amano K, Huebner JL, Stabler TV, Tanaka M, McCulloch CE, Lobach I, Lane NE, Kraus VB, Ma CB, Li X. PMID: 29364702.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP. Neurology. 2018 01 23; 90(4):e273-e281. Rojas JC, Bang J, Lobach IV, Tsai RM, Rabinovici GD, Miller BL, Boxer AL. PMID: 29282336.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    24. Effect of Background Parenchymal Enhancement on Breast MR Imaging Interpretive Performance in Community-based Practices. Radiology. 2018 03; 286(3):822-829. Ray KM, Kerlikowske K, Lobach IV, Hofmann MB, Greenwood HI, Arasu VA, Hylton NM, Joe BN. PMID: 29072981.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    25. Clustered Microcysts on Breast Ultrasound: What Is an Appropriate Management Recommendation? AJR Am J Roentgenol. 2017 Dec; 209(6):W395-W399. PMID: 28929806.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Altered cargo proteins of human plasma endothelial cell-derived exosomes in atherosclerotic cerebrovascular disease. FASEB J. 2017 08; 31(8):3689-3694. Goetzl EJ, Schwartz JB, Mustapic M, Lobach IV, Daneman R, Abner EL, Jicha GA. PMID: 28476896.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    27. A multicenter study to define sarcopenia in patients with end-stage liver disease. Liver Transpl. 2017 05; 23(5):625-633. PMID: 28240805.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    28. Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8187-E8196. PMID: 27911827.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    29. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 10 04; 87(14):1523. PMID: 27698154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro. J Bone Miner Res. 2016 12; 31(12):2173-2192. PMID: 27345526.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    31. Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease. FASEB J. 2016 12; 30(12):4141-4148. PMID: 27601437.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    32. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. PMID: 27429218.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    33. Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma. J Clin Invest. 2016 09 01; 126(9):3447-52. PMID: 27525433.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    34. Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease. FASEB J. 2016 11; 30(11):3853-3859. PMID: 27511944.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    35. Intravenous heparin dosing strategy in hospitalized patients with atrial dysrhythmias. J Thromb Thrombolysis. 2016 Aug; 42(2):179-85. PMID: 26951166.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy. Parkinsonism Relat Disord. 2016 07; 28:29-35. PMID: 27132501.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    37. Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials. Parkinsonism Relat Disord. 2016 07; 28:41-48. PMID: 27172829.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. Power calculations and placebo effect for future clinical trials in progressive supranuclear palsy. Mov Disord. 2016 05; 31(5):742-7. PMID: 26948290.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Adverse Trends in Ischemic Heart Disease Mortality among Young New Yorkers, Particularly Young Black Women. PLoS One. 2016; 11(2):e0149015. PMID: 26882207.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 Feb 16; 86(7):600-10. PMID: 26802093.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    41. Identifying preoperative language tracts and predicting postoperative functional recovery using HARDI q-ball fiber tractography in patients with gliomas. J Neurosurg. 2016 07; 125(1):33-45. PMID: 26654181.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    42. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug; 72(8):897-904. PMID: 26053119.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    43. Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models. Genetics. 2015 Aug; 200(4):1089-104. PMID: 26058849.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Comparing CSF biomarkers and brain MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Apr; 5(2):116-125. PMID: 26137420.
      View in: PubMed   Mentions:
    45. Diabetes and ischemic heart disease death in people age 25-54: a multiple-cause-of-death analysis based on over 400?000 deaths from 1990 to 2008 in New York City. Clin Cardiol. 2015 Feb; 38(2):114-20. Quinones A, Lobach I, Maduro GA, Smilowitz NR, Reynolds HR. PMID: 25716311.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54. PMID: 25367029.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    47. A risk score for prediction of hyperglycemia at coronary angiography. JACC Cardiovasc Interv. 2014 Oct; 7(10):1199-201. PMID: 25240543.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    48. Generalized functional linear models for gene-based case-control association studies. Genet Epidemiol. 2014 Nov; 38(7):622-637. PMID: 25203683.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    49. Interleukin-6, age, and corpus callosum integrity. PLoS One. 2014; 9(9):e106521. PMID: 25188448.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    50. Spinal cord gray matter atrophy correlates with multiple sclerosis disability. Ann Neurol. 2014 Oct; 76(4):568-80. PMID: 25087920.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    51. Frontal white matter tracts sustaining speech production in primary progressive aphasia. J Neurosci. 2014 Jul 16; 34(29):9754-67. PMID: 25031413.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    52. Divergent CSF t alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2015 Mar; 86(3):244-50. PMID: 24899730.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    53. Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial. Lancet Neurol. 2014 Jul; 13(7):676-85. PMID: 24873720.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCTClinical Trials
    54. From door-to-balloon time to contact-to-device time: predictors of achieving target times in patients with ST-elevation myocardial infarction. Clin Cardiol. 2014 Jul; 37(7):389-94. PMID: 24700343.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    55. Periprocedural glycemic control in patients with diabetes mellitus undergoing coronary angiography with possible percutaneous coronary intervention. Am J Cardiol. 2014 May 01; 113(9):1474-80. PMID: 24630791.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    56. Application of quantitative DTI metrics in sporadic CJD. Neuroimage Clin. 2014; 4:426-35. PMID: 24624328.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    57. Genotype-Based Association Mapping of Complex Diseases: Gene-Gene and Gene-Environment Interactions in Presence of Linkage Disequilibrium. Statistics and Its Interface. 2014; (7):51-60. Lobach, I., Fan, R., Manga, P.
    58. Genotype-based association models of complex diseases to detect gene-gene and gene-environment interactions. Stat Interface. 2014; 7(1):51-60. PMID: 26191336.
      View in: PubMed   Mentions:
    59. Handedness and language learning disability differentially distribute in progressive aphasia variants. Brain. 2013 Nov; 136(Pt 11):3461-73. PMID: 24056533.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    60. Modifiable risk factor burden and the prevalence of peripheral artery disease in different vascular territories. J Vasc Surg. 2013 Sep; 58(3):673-81.e1. PMID: 23642926.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    61. Capgras syndrome in Dementia with Lewy Bodies. Int Psychogeriatr. 2013 May; 25(5):843-9. PMID: 23211760.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    62. Mean platelet volume and long-term mortality in patients undergoing percutaneous coronary intervention. Am J Cardiol. 2013 Jan 15; 111(2):185-9. PMID: 23102880.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    63. Effectiveness of smoking-cessation interventions for urban hospital patients: study protocol for a randomized controlled trial. Trials. 2012 Aug 01; 13:126. PMID: 22852878.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    64. Very long-term clinical follow-up after fractional flow reserve-guided coronary revascularization. J Invasive Cardiol. 2012 Jul; 24(7):309-15. PMID: 22781467.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    65. Inverse relationship between cirrhosis and massive tumours in hepatocellular carcinoma. HPB (Oxford). 2012 Nov; 14(11):741-5. PMID: 23043662.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    66. Genotype-Based Bayesian Analysis of Gene-Environment Interactions with Multiple Genetic Markers and Misclassification in Environmental Factors. J Probab Stat. 2012; 2012. PMID: 26180529.
      View in: PubMed   Mentions:
    67. Risk factors for early-onset and late-onset hepatocellular carcinoma in Asian immigrants with hepatitis B in the United States. Am J Gastroenterol. 2011 Nov; 106(11):1994-2000. PMID: 21912436.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    68. Mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease. Circulation. 2011 Sep 27; 124(13):1414-25. PMID: 21900087.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCTClinical Trials
    69. Blood pressure targets in subjects with type 2 diabetes mellitus/impaired fasting glucose: observations from traditional and bayesian random-effects meta-analyses of randomized trials. Circulation. 2011 Jun 21; 123(24):2799-810, 9 p following 810. PMID: 21632497.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    70. Mexican urban occupational health in the US: a population at risk. J Community Health. 2011 Apr; 36(2):175-9. Gany F, Dobslaw R, Ramirez J, Tonda J, Lobach I, Leng J. PMID: 20614170.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    71. Factors associated with frequent utilization of crisis substance use detoxification services. J Addict Dis. 2011 Apr; 30(2):116-22. PMID: 21491293.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    72. Cancer portal project: a multidisciplinary approach to cancer care among Hispanic patients. J Oncol Pract. 2011 Jan; 7(1):31-8. PMID: 21532808.
      View in: PubMed   Mentions: 11     Fields:    
    73. Semiparametric Bayesian analysis of gene-environment interactions with error in measurement of environmental covariates and missing genetic data. Stat Interface. 2011; 4(3):305-316. PMID: 21949562.
      View in: PubMed   Mentions:
    74. Genotype-based association mapping of complex diseases: gene-environment interactions with multiple genetic markers and measurement error in environmental exposures. Genet Epidemiol. 2010 Dec; 34(8):792-802. Lobach I, Fan R, Carroll RJ. PMID: 21031455.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    75. Normal intima-media thickness on carotid ultrasound reliably excludes an ischemic cause of cardiomyopathy. Am Heart J. 2010 Jun; 159(6):1059-66. Reynolds HR, Steckman DA, Tunick PA, Kronzon I, Lobach I, Rosenzweig BP. PMID: 20569720.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    76. Haplotype-based regression analysis and inference of case-control studies with unphased genotypes and measurement errors in environmental exposures. Biometrics. 2008 Sep; 64(3):673-84. Lobach I, Carroll RJ, Spinka C, Gail MH, Chatterjee N. PMID: 18047538.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    77. Genotype-based Bayesian Analysis of Gene-Environment Interactions with Multiple Genetic Markers and Misclassification in Environmental Factors. Journal of Probability and Statistics. 2012. Lobach, I and Fan, R. View Publication.
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