James Huang, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
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    Collapse Education and Training
    Harvard College, Cambridge, MAAB06/1986Biochemical Sciences
    Baylor College of Medicine, Houston, TXMD05/1991Medicine
    Johns Hopkins Hospital, Baltimore, MD06/1994Pediatrics Residency
    Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA06/1997Pediatric Hematology/Oncology Fellowship

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients. Pediatr Blood Cancer. 2022 05; 69(5):e29641. Higham CS, Shimano KA, Melton A, Kharbanda S, Chu J, Dara J, Winestone LE, Hermiston ML, Huang JN, Dvorak CC. PMID: 35253361.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    2. Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 11 01; 96(11):1491-1504. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. PMID: 34342889.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    3. Plasma-derived factor X concentrate compassionate use for hereditary factor X deficiency: Long-term safety and efficacy in a retrospective data-collection study. Res Pract Thromb Haemost. 2021 Jul; 5(5):e12550. Huang JN, Liesner R, Austin SK, Kavakli K, Akanezi C. PMID: 34263102; PMCID: PMC8268662.
      View in: PubMed   Mentions: 3  
    4. Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Nat Commun. 2021 02 26; 12(1):1334. Kennedy AL, Myers KC, Bowman J, Gibson CJ, Camarda ND, Furutani E, Muscato GM, Klein RH, Ballotti K, Liu S, Harris CE, Galvin A, Malsch M, Dale D, Gansner JM, Nakano TA, Bertuch A, Vlachos A, Lipton JM, Castillo P, Connelly J, Churpek J, Edwards JR, Hijiya N, Ho RH, Hofmann I, Huang JN, Keel S, Lamble A, Lau BW, Norkin M, Stieglitz E, Stock W, Walkovich K, Boettcher S, Brendel C, Fleming MD, Davies SM, Weller EA, Bahl C, Carter SL, Shimamura A, Lindsley RC. PMID: 33637765; PMCID: PMC7910481.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    5. A study assessing the feasibility of randomization of pediatric and young adult patients between matched unrelated donor bone marrow transplantation and immune-suppressive therapy for newly diagnosed severe aplastic anemia: A joint pilot trial of the North American Pediatric Aplastic Anemia Consortium and the Pediatric Transplantation and Cellular Therapy Consortium. Pediatr Blood Cancer. 2020 10; 67(10):e28444. Pulsipher MA, Lehmann LE, Bertuch AA, Sasa G, Olson T, Nakano T, Gilio A, Burroughs LM, Lipton JM, Huang JN, Dickerson K, Bertaina A, Zhuang C, Malsch M, Fleming M, Weller E, Shimamura A, Williams DA. PMID: 32776425; PMCID: PMC9533334.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study. Haematologica. 2019 10; 104(10):1974-1983. Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. PMID: 30948484; PMCID: PMC6886407.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    7. Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency. Biol Blood Marrow Transplant. 2019 07; 25(7):1355-1362. Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ. PMID: 30876930; PMCID: PMC7384257.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    8. Investigation of Pediatric Anemia in the Commonwealth of the Northern Mariana Islands. Matern Child Health J. 2019 Mar; 23(3):416-421. Lin TF, Huang JN, Cash HL. PMID: 30661189.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Understanding the evolving phenotype of vascular complications in telomere biology disorders. Angiogenesis. 2019 02; 22(1):95-102. Higgs C, Crow YJ, Adams DM, Chang E, Hayes D, Herbig U, Huang JN, Himes R, Jajoo K, Johnson FB, Reynolds SD, Yonekawa Y, Armanios M, Boulad F, DiNardo CD, Dufour C, Goldman FD, Khan S, Kratz C, Myers KC, Raghu G, Alter BP, Aubert G, Bhala S, Cowen EW, Dror Y, El-Youssef M, Friedman B, Giri N, Helms Guba L, Khincha PP, Lin TF, Longhurst H, McReynolds LJ, Nelson A, Olson T, Pariser A, Perona R, Sasa G, Schratz K, Simonetto DA, Townsley D, Walsh M, Stevens K, Agarwal S, Bertuch AA, Savage SA, Clinical Care Consortium for Telomere-associated Ailments (CCCTAA). PMID: 30168024.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    10. Comprehensive Review of Preschool Age Anemia in the Pacific Island Jurisdictions. Hawaii J Med Public Health. 2017 12; 76(12):331-336. Lin TF, Huang JN, Cash HL. PMID: 29242758; PMCID: PMC5725618.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Capacity Building for Rare Bleeding Disorders in the Remote Commonwealth of the Northern Mariana Islands. Am J Public Health. 2016 Apr; 106(4):658-61. Lin TF, Carhill P, Huang JN, Baker JR. PMID: 26890163; PMCID: PMC4816151.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    12. Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Ann Hematol. 2014 Jul; 93(7):1139-48. Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP. PMID: 24577514; PMCID: PMC4467727.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer. 2014 May; 61(5):869-74. Williams DA, Bennett C, Bertuch A, Bessler M, Coates T, Corey S, Dror Y, Huang J, Lipton J, Olson TS, Reiss UM, Rogers ZR, Sieff C, Vlachos A, Walkovich K, Wang W, Shimamura A. PMID: 24285674; PMCID: PMC4280184.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2013 Oct; 98(4):960-71. Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP. PMID: 23945720; PMCID: PMC3778866.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    15. Re: 24-year-old man with previously diagnosed hemophilia. Clin Chem. 2012 Jul; 58(7):1090. Huang JN. PMID: 22745259.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. J Clin Invest. 2012 Jan; 122(1):408-18. Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA. PMID: 22156199; PMCID: PMC3248292.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansCells
    17. Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. PLoS One. 2011; 6(10):e26437. Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA. PMID: 22028878; PMCID: PMC3197646.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    18. Functions of the mitotic B-type cyclins CLB1, CLB2, and CLB3 at mitotic exit antagonized by the CDC14 phosphatase. Fungal Genet Biol. 2011 Oct; 48(10):966-78. Tzeng YW, Huang JN, Schuyler SC, Wu CH, Juang YL. PMID: 21784165.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    19. Pseudotumor of the mandible as first presentation of hemophilia in a 2-year-old male: a case report and review of jaw pseudotumors of hemophilia. Head Neck Pathol. 2011 Sep; 5(3):226-32. Cox DP, Solar A, Huang J, Chigurupati R. PMID: 21567186; PMCID: PMC3173544.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    20. Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover. Bone. 2011 Jun 01; 48(6):1305-12. Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS. PMID: 21443975; PMCID: PMC3095710.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    21. Clinical spectrum and molecular pathophysiology of Shwachman-Diamond syndrome. Curr Opin Hematol. 2011 Jan; 18(1):30-5. Huang JN, Shimamura A. PMID: 21124213; PMCID: PMC3485416.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    22. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010 Sep; 41(9):2108-29. Morgenstern LB, Hemphill JC, Anderson C, Becker K, Broderick JP, Connolly ES, Greenberg SM, Huang JN, MacDonald RL, Messé SR, Mitchell PH, Selim M, Tamargo RJ, American Heart Association Stroke Council and Council on Cardiovascular Nursing. PMID: 20651276; PMCID: PMC4462131.
      View in: PubMed   Mentions: 451     Fields:    Translation:Humans
    23. Factor V deficiency: a concise review. Haemophilia. 2008 Nov; 14(6):1164-9. Huang JN, Koerper MA. PMID: 19141156.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    24. Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J Cell Biol. 2001 Jul 09; 154(1):85-94. Huang JN, Park I, Ellingson E, Littlepage LE, Pellman D. PMID: 11448992; PMCID: PMC2196868.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    25. Low-molecular-weight heparins. Hematol Oncol Clin North Am. 1998 Dec; 12(6):1251-81, vi-vii. Huang JN, Shimamura A. PMID: 9922935.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Selection and analysis of rare second-site suppressors of Drosophila RNA polymerase II mutations. Mol Gen Genet. 1998 Jun; 258(5):457-65. Krasnoselskaya I, Huang J, Jones T, Dezan C, Mortin MA. PMID: 9669327.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    27. APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science. 1997 Feb 28; 275(5304):1311-4. Juang YL, Huang J, Peters JM, McLaughlin ME, Tai CY, Pellman D. PMID: 9036857.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    28. Surface hydrophobicity and water transport of the toad urinary bladder: effects of vasopressin. J Membr Biol. 1988 Dec; 106(2):119-22. Dial EJ, Huang J, O'Neil RG, Hills BA, Lichtenberger LM. PMID: 3147334.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    29. Antagonistic interactions between alleles of the RpII215 locus in Drosophila melanogaster. Genetics. 1988 Aug; 119(4):863-73. Mortin MA, Kim WJ, Huang J. PMID: 3137121; PMCID: PMC1203470.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    30. Monoamine oxidase: an important intracellular regulator of gastrin release in the rat. Gastroenterology. 1986 Apr; 90(4):1018-23. Dial EJ, Huang J, Delansorne R, Lichtenberger LM. PMID: 3081396.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
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