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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. 2021 Apr 29; 184(9):2503-2519.e17.
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS. PMID: 33838111.
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PubMed Mentions:
7 Fields:
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BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2. bioRxiv. 2021 Jan 19.
Tian R, Samelson AJ, Rezelj VV, Chen M, Ramadoss GN, Guo X, Kain AM, Tran QD, Lim SA, Lui I, Nunez J, Rockwood SJ, Liu N, Carlson-Stevermer J, Oki J, Maures T, Holden K, Weissman JS, Wells JA, Conklin B, Vignuzzi M, Kampmann M. PMID: 33501440.
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Pervasive functional translation of noncanonical human open reading frames. Science. 2020 03 06; 367(6482):1140-1146.
Chen J, Brunner AD, Cogan JZ, Nuñez JK, Fields AP, Adamson B, Itzhak DN, Li JY, Mann M, Leonetti MD, Weissman JS. PMID: 32139545.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nat Methods. 2017 Dec; 14(12):1163-1166.
Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK. PMID: 29083402.
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55 Fields:
Translation:
HumansCells
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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21.
Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. PMID: 27984733.
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PubMed Mentions:
208 Fields:
Translation:
HumansAnimalsCells
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CRISPR Immunological Memory Requires a Host Factor for Specificity. Mol Cell. 2016 06 16; 62(6):824-833.
Nuñez JK, Bai L, Harrington LB, Hinder TL, Doudna JA. PMID: 27211867.
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56 Fields:
Translation:
Cells
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Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering. ACS Chem Biol. 2016 Mar 18; 11(3):681-8.
Nuñez JK, Harrington LB, Doudna JA. PMID: 26857072.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering. Cell. 2016 Jan 14; 164(1-2):29-44.
Wright AV, Nuñez JK, Doudna JA. PMID: 26771484.
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PubMed Mentions:
327 Fields:
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HumansAnimalsCells
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Foreign DNA capture during CRISPR-Cas adaptive immunity. Nature. 2015 Nov 26; 527(7579):535-8.
Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA. PMID: 26503043.
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PubMed Mentions:
71 Fields:
Translation:
Cells
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Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity. Nature. 2015 Mar 12; 519(7542):193-8.
Nuñez JK, Lee AS, Engelman A, Doudna JA. PMID: 25707795.
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PubMed Mentions:
126 Fields:
Translation:
Cells
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Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nat Struct Mol Biol. 2014 Jun; 21(6):528-34.
Nuñez JK, Kranzusch PJ, Noeske J, Wright AV, Davies CW, Doudna JA. PMID: 24793649.
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153 Fields:
Translation:
Cells
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Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1. Nat Struct Mol Biol. 2012 Dec; 19(12):1266-72.
Musselman CA, Avvakumov N, Watanabe R, Abraham CG, Lalonde ME, Hong Z, Allen C, Roy S, Nuñez JK, Nickoloff J, Kulesza CA, Yasui A, Côté J, Kutateladze TG. PMID: 23142980.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells