Jason Northey, PhD

Title(s)Specialist, Surgery
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #550
San Francisco CA 94143
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    University of California, San Francisco, CA2021Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk. Cell Stem Cell. 2024 Jan 04; 31(1):106-126.e13. Northey JJ, Hayward MK, Yui Y, Stashko C, Kai F, Mouw JK, Thakar D, Lakins JN, Ironside AJ, Samson S, Mukhtar RA, Hwang ES, Weaver VM. PMID: 38181747.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Nat Biotechnol. 2023 Aug 03. Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. PMID: 37537499.
      View in: PubMed   Mentions: 8     Fields:    
    3. A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer. Nat Commun. 2023 06 15; 14(1):3561. Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM. PMID: 37322009; PMCID: PMC10272194.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Extracellular Matrix Glycation and Crosslinking in Mammary Tumor Progression. Methods Mol Biol. 2023; 2614:247-260. Northey JJ, Weaver VM. PMID: 36587129; PMCID: PMC10977607.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Mechanosensitive Steroid Hormone Signaling and Cell Fate. Endocrinology. 2022 08 01; 163(8). Northey JJ, Weaver VM. PMID: 35678467; PMCID: PMC9237634.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells. EMBO J. 2022 09 01; 41(17):e109205. Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM. PMID: 35880301; PMCID: PMC9434103.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    7. Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity. Nat Cancer. 2022 06; 3(6):734-752. Tsai KK, Huang SS, Northey JJ, Liao WY, Hsu CC, Cheng LH, Werner ME, Chuu CP, Chatterjee C, Lakins JN, Weaver VM. PMID: 35618935; PMCID: PMC9246917.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    8. NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation. Transl Oncol. 2022 Feb; 16:101325. Samson S, Northey JJ, Acerbi I, Goga A, Flink CL, Weaver VM, LaBarge MA. PMID: 34974281; PMCID: PMC8728534.
      View in: PubMed   Mentions:
    9. Mechanical Pressure Driving Proteoglycan Expression in Mammographic Density: a Self-perpetuating Cycle? J Mammary Gland Biol Neoplasia. 2021 09; 26(3):277-296. Reye G, Huang X, Haupt LM, Murphy RJ, Northey JJ, Thompson EW, Momot KI, Hugo HJ. PMID: 34449016; PMCID: PMC8566410.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    10. RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers. Cancers (Basel). 2021 Jun 29; 13(13). Reye G, Huang X, Britt KL, Meinert C, Blick T, Xu Y, Momot KI, Lloyd T, Northey JJ, Thompson EW, Hugo HJ. PMID: 34209669; PMCID: PMC8269117.
      View in: PubMed   Mentions: 1  
    11. Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer. J Exp Med. 2021 05 03; 218(5). Drain AP, Zahir N, Northey JJ, Zhang H, Huang PJ, Maller O, Lakins JN, Yu X, Leight JL, Alston-Mills BP, Hwang ES, Chen YY, Park CC, Weaver VM. PMID: 33822843; PMCID: PMC8025243.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    12. Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. J Clin Invest. 2020 11 02; 130(11):5721-5737. Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. PMID: 32721948; PMCID: PMC7598051.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    13. New Horizons in Advocacy Engaged Physical Sciences and Oncology Research. Trends Cancer. 2018 04; 4(4):260-264. Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. PMID: 29606307; PMCID: PMC6932745.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discov. 2017 11; 7(11):1224-1237. Northey JJ, Przybyla L, Weaver VM. PMID: 29038232; PMCID: PMC5679454.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    15. PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs. Cell Metab. 2017 Nov 07; 26(5):778-787.e5. Andrzejewski S, Klimcakova E, Johnson RM, Tabariès S, Annis MG, McGuirk S, Northey JJ, Chénard V, Sriram U, Papadopoli DJ, Siegel PM, St-Pierre J. PMID: 28988825.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    16. Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. Mol Cell Biol. 2016 05 15; 36(10):1509-25. Cyr-Depauw C, Northey JJ, Tabariès S, Annis MG, Dong Z, Cory S, Hallett M, Rennhack JP, Andrechek ER, Siegel PM. PMID: 26976638; PMCID: PMC4859683.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    17. Fighting the force: Potential of homeobox genes for tumor microenvironment regulation. Biochim Biophys Acta. 2015 Apr; 1855(2):248-53. Northcott JM, Northey JJ, Barnes JM, Weaver VM. PMID: 25818365; PMCID: PMC4433566.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    18. A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. J Cell Sci. 2013 May 01; 126(Pt 9):1981-91. Ngan E, Northey JJ, Brown CM, Ursini-Siegel J, Siegel PM. PMID: 23447672; PMCID: PMC3791827.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    19. Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion, and metastasis. J Biol Chem. 2013 Feb 15; 288(7):5210-22. Northey JJ, Dong Z, Ngan E, Kaplan A, Hardy WR, Pawson T, Siegel PM. PMID: 23277357; PMCID: PMC3576125.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    20. Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion. Mol Cell Biol. 2008 May; 28(10):3162-76. Northey JJ, Chmielecki J, Ngan E, Russo C, Annis MG, Muller WJ, Siegel PM. PMID: 18332126; PMCID: PMC2423163.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    21. Targeting aberrant TGF-beta signaling in pre-clinical models of cancer. Anticancer Agents Med Chem. 2007 Sep; 7(5):504-14. Mourskaia AA, Northey JJ, Siegel PM. PMID: 17896911.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
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