Jayant Rajan, MD, PhD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Phone628-206-6103
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    I am an infectious diseases physician by training with a background in immunology, epidemiology/biostatistics and computation. My research is largely translational with my primary focus being the use of unbiased serological profiling to understand the humoral immune response to flavivirus infections. I believe that this approach, combined with others can aid us in vaccine design. I am also interested in expanding this technique to other infectious diseases.

    My second area of interest is more computation-focused. In collaboration with other investigators at UCSF, I have developed a gene expression signature that we believe can be an effective tool for TB-screening in people with HIV in TB-endemic areas. This work fits into a larger interest in trying to understand how to more effectively leverage data generated from high throughput assays.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine-induced antibody and T cell immunity and function. JCI Insight. 2022 02 22; 7(4). Sabatino JJ, Mittl K, Rowles WM, McPolin K, Rajan JV, Laurie MT, Zamecnik CR, Dandekar R, Alvarenga BD, Loudermilk RP, Gerungan C, Spencer CM, Sagan SA, Augusto DG, Alexander JR, DeRisi JL, Hollenbach JA, Wilson MR, Zamvil SS, Bove R. PMID: 35030101; PMCID: PMC8876469.
      View in: PubMed   Mentions:
    2. Impact of multiple sclerosis disease-modifying therapies on SARS-CoV-2 vaccine-induced antibody and T cell immunity. medRxiv. 2021 Sep 20. Sabatino JJ, Mittl K, Rowles W, Mcpolin K, Rajan JV, Zamecnik CR, Dandekar R, Alvarenga BD, Loudermilk RP, Gerungan C, Spencer CM, Sagan SA, Augusto DG, Alexander J, Hollenbach JA, Wilson MR, Zamvil SS, Bove R. PMID: 34580672; PMCID: PMC8475959.
      View in: PubMed   Mentions:
    3. Phage display demonstrates durable differences in serological profile by route of inoculation in primary infections of non-human primates with Dengue Virus 1. Sci Rep. 2021 05 24; 11(1):10823. Rajan JV, McCracken M, Mandel-Brehm C, Gromowski G, Pollett S, Jarman R, DeRisi JL. PMID: 34031504; PMCID: PMC8144558.
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    4. ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens. Cell Rep Med. 2020 10 20; 1(7):100123. Zamecnik CR, Rajan JV, Yamauchi KA, Mann SA, Loudermilk RP, Sowa GM, Zorn KC, Alvarenga BD, Gaebler C, Caskey M, Stone M, Norris PJ, Gu W, Chiu CY, Ng D, Byrnes JR, Zhou XX, Wells JA, Robbiani DF, Nussenzweig MC, DeRisi JL, Wilson MR. PMID: 32995758; PMCID: PMC7513813.
      View in: PubMed   Mentions: 20  
    5. A Novel, 5-Transcript, Whole-blood Gene-expression Signature for Tuberculosis Screening Among People Living With Human Immunodeficiency Virus. Clin Infect Dis. 2019 06 18; 69(1):77-83. Rajan JV, Semitala FC, Mehta T, Seielstad M, Montalvo L, Andama A, Asege L, Nakaye M, Katende J, Mwebe S, Kamya MR, Yoon C, Cattamanchi A. PMID: 30462176; PMCID: PMC6579960.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    6. Prevalence and risk factors for latent tuberculosis infection among primary health care workers in Brazil. Cad Saude Publica. 2017 12 18; 33(12):e00154916. Prado TND, Riley LW, Sanchez M, Fregona G, Nóbrega RLP, Possuelo LG, Zandonade E, Locatelli RL, Souza FM, Rajan JV, Maciel ELN. PMID: 29267691.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    7. Differences in the Prevalence of Non-Communicable Disease between Slum Dwellers and the General Population in a Large Urban Area in Brazil. Trop Med Infect Dis. 2017 Sep 16; 2(3). Snyder RE, Rajan JV, Costa F, Lima HCAV, Calcagno JI, Couto RD, Riley LW, Reis MG, Ko AI, Ribeiro GS. PMID: 30270904; PMCID: PMC6082112.
      View in: PubMed   Mentions: 1  
    8. Diabetes increases the risk of recent-transmission tuberculosis in household contacts in São Paulo, Brazil. Int J Tuberc Lung Dis. 2017 08 01; 21(8):916-921. Rajan JV, Ferrazoli L, Waldman EA, Simonsen V, Ferreira P, Telles MA, Riley LW. PMID: 28786800.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    9. Clinical and epidemiological characteristics associated with unfavorable tuberculosis treatment outcomes in TB-HIV co-infected patients in Brazil: a hierarchical polytomous analysis. Braz J Infect Dis. 2017 Mar - Apr; 21(2):162-170. Prado TN, Rajan JV, Miranda AE, Dias ED, Cosme LB, Possuelo LG, Sanchez MN, Golub JE, Riley LW, Maciel EL. PMID: 27936379.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    10. Understanding the barriers to successful adoption and use of a mobile health information system in a community health center in São Paulo, Brazil: a cohort study. BMC Med Inform Decis Mak. 2016 11 17; 16(1):146. Rajan JV, Moura J, Gourley G, Kiso K, Sizilio A, Cortez AM, Riley LW, Veras MA, Sarkar U. PMID: 27855685; PMCID: PMC5114819.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
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