Jean Publicover, PhD
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Title(s) | Assistant Professor, Medicine |
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School | School of Medicine |
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Address | 513 Parnassus Ave, MSB San Francisco CA 94117
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Phone | 415-476-3547 |
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vCard | Download vCard |
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Biography Yale University, New Haven, CT | Ph.D. | 05/2006 | Viral Pathogenesis and Vaccine Development | University of Rochester, Rochester, NY | B.S. | 05/2001 | MIcrobiology |
| 2008 | | UCSF Postdoctoral Research in Hepatology Fellow | | 2008
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| 2011 | A.P. Giannini Foundation Fellow | | 2008
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| 2011 | NIH LRP Pediatric Research Recipient | | 2013
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| 2018 | NIDDK K01 Mentored Research Scientist Development Award | | 2015
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| 2016 | UCSF Liver Center Pilot Feasibility Grant Awardee |
Overview The goal of my research is to identify factors that influence the initiation of effective immune responses to HBV in the liver. Currently, my focus is on understanding the role of the liver as a site of immune priming to hepatotropic pathogens and the influence of commensal bacteria on the liver priming environment. I am also very interested visualizing of immune structures in the liver by immunofluorescent staining of liver tissue.
Research Bibliographic
Altmetrics Details
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Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Integrin avß8-expressing tumor cells evade host immunity by regulating TGF-ß activation in immune cells. JCI Insight. 2018 10 18; 3(20).
Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashimoto M, Ma R, Levine MD, Publicover J, Potts R, Jespersen JM, Campbell MG, Conrad F, Marks JD, Cheng Y, Baron JL, Nishimura SL. PMID: 30333313.
View in: PubMed Mentions: 15 Fields: Translation: HumansAnimalsCells
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An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Sci Transl Med. 2018 03 21; 10(433).
Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL. PMID: 29563320.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
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Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells. Cell Med. 2017; 9(3):117-125.
Fomin ME, Beyer AI, Publicover J, Lu K, Bakkour S, Simmons G, Muench MO. PMID: 28713641.
View in: PubMed Mentions:
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Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man. Hepatology. 2016 Jan; 63(1):260.
Publicover J, Jespersen JM, Johnson AJ, Nishimura SL, Goodsell A, Wakil AE, Rosenthal P, Pai E, Avanesyan L, Cooper S, Baron JL. PMID: 26457468.
View in: PubMed Mentions: Fields: Translation: HumansAnimals
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Production of factor VIII by human liver sinusoidal endothelial cells transplanted in immunodeficient uPA mice. PLoS One. 2013; 8(10):e77255.
Fomin ME, Zhou Y, Beyer AI, Publicover J, Baron JL, Muench MO. PMID: 24167566.
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S-3 Age-dependent hepatic lymphoid organization directs immune priming, cytokine production, and successful immunity to Hepatitis B virus. Cytokine. 2013 Sep 1; 63(3):241.
Jean Publicover, Anuj Gaggar, Stephen Nishimura, Christine M. Van Horn, Amanda Goodsell, Marcus O. Muench, R. Lee Reinhardt, Nico van Rooijen, Adil E. Wakil Marion Peters, Jason G. Cyster, David J. Erle, Philip Rosenthal, Lia Avanesyan, Rosanne Spolski, Warren J. Leonard, Stewart Cooper, Jody L. Baron. .
View in: Publisher Site Mentions:
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Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest. 2013 Sep; 123(9):3728-39.
Publicover J, Gaggar A, Nishimura S, Van Horn CM, Goodsell A, Muench MO, Reinhardt RL, van Rooijen N, Wakil AE, Peters M, Cyster JG, Erle DJ, Rosenthal P, Cooper S, Baron JL. PMID: 23925290.
View in: PubMed Mentions: 37 Fields: Translation: HumansAnimalsCells
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Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012 Jul; 18(7):1060-8.
Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, Baron JL, Moody DB, Liang TJ, Blumberg RS. PMID: 22706385.
View in: PubMed Mentions: 96 Fields: Translation: HumansAnimalsCells
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742 Hepatitis B Virus Infection Leads to Alterations in the Repertoire of Self Lipid Antigens Presented by Hepatocytes and is Associated With Direct and Indirect Activation of Natural Killer T Cells. Gastroenterology. 2012 May 1; 142(5):s-927.
Sebastian Zeissig, Kazumoto Murata, Lindsay Sweet, Jean Publicover, Zongyi Hu, Arthur Kaser, Alexander Arlt, Rainer Günther, Jochen Hampe, Stefan Schreiber, Jody Baron, D. Branch Moody, T Jake Liang, Richard S. Blumberg. .
View in: Publisher Site Mentions:
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Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin avß8-mediated activation of TGF-ß. J Clin Invest. 2011 Jul; 121(7):2863-75.
Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. PMID: 21646718.
View in: PubMed Mentions: 70 Fields: Translation: HumansAnimalsCells
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IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B. J Clin Invest. 2011 Mar; 121(3):1154-62.
Publicover J, Goodsell A, Nishimura S, Vilarinho S, Wang ZE, Avanesyan L, Spolski R, Leonard WJ, Cooper S, Baron JL. PMID: 21393863.
View in: PubMed Mentions: 60 Fields: Translation: HumansAnimalsCells
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Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5839-43.
Rose NF, Publicover J, Chattopadhyay A, Rose JK. PMID: 18391206.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCellsPHPublic Health
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Single-dose, therapeutic vaccination of mice with vesicular stomatitis virus expressing human papillomavirus type 16 E7 protein. Clin Vaccine Immunol. 2008 May; 15(5):817-24.
Liao JB, Publicover J, Rose JK, DiMaio D. PMID: 18337377.
View in: PubMed Mentions: 10 Fields: Translation: AnimalsCells
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Requirement for CD4 T cell help in maintenance of memory CD8 T cell responses is epitope dependent. J Immunol. 2007 May 15; 178(10):6350-8.
Ramsburg EA, Publicover JM, Coppock D, Rose JK. PMID: 17475864.
View in: PubMed Mentions: 19 Fields: Translation: AnimalsCells
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Replication and propagation of attenuated vesicular stomatitis virus vectors in vivo: vector spread correlates with induction of immune responses and persistence of genomic RNA. J Virol. 2007 Feb; 81(4):2078-82.
Simon ID, Publicover J, Rose JK. PMID: 17151110.
View in: PubMed Mentions: 28 Fields: Translation: AnimalsCellsPHPublic Health
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Rapid pathogenesis induced by a vesicular stomatitis virus matrix protein mutant: viral pathogenesis is linked to induction of tumor necrosis factor alpha. J Virol. 2006 Jul; 80(14):7028-36.
Publicover J, Ramsburg E, Robek M, Rose JK. PMID: 16809308.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
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A vesicular stomatitis virus recombinant expressing granulocyte-macrophage colony-stimulating factor induces enhanced T-cell responses and is highly attenuated for replication in animals. J Virol. 2005 Dec; 79(24):15043-53.
Ramsburg E, Publicover J, Buonocore L, Poholek A, Robek M, Palin A, Rose JK. PMID: 16306575.
View in: PubMed Mentions: 63 Fields: Translation: AnimalsCellsPHPublic Health
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A single-cycle vaccine vector based on vesicular stomatitis virus can induce immune responses comparable to those generated by a replication-competent vector. J Virol. 2005 Nov; 79(21):13231-8.
Publicover J, Ramsburg E, Rose JK. PMID: 16227246.
View in: PubMed Mentions: 39 Fields: Translation: AnimalsCellsPHPublic Health
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Characterization of nonpathogenic, live, viral vaccine vectors inducing potent cellular immune responses. J Virol. 2004 Sep; 78(17):9317-24.
Publicover J, Ramsburg E, Rose JK. PMID: 15308726.
View in: PubMed Mentions: 39 Fields: Translation: AnimalsCellsPHPublic Health
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Year | Publications |
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2004 | 1 | 2005 | 2 | 2006 | 2 | 2007 | 1 | 2008 | 2 | 2011 | 2 | 2012 | 2 | 2013 | 3 | 2015 | 1 | 2016 | 1 | 2018 | 2 |
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This graph shows the number and percent of publications by field.
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