-
PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription. Sci Rep. 2017 03 27; 7:45394.
Faust TB, Li Y, Jang GM, Johnson JR, Yang S, Weiss A, Krogan NJ, Frankel AD. PMID: 28345603; PMCID: PMC5366948.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. Elife. 2017 03 02; 6.
Elwell CA, Czudnochowski N, von Dollen J, Johnson JR, Nakagawa R, Mirrashidi K, Krogan NJ, Engel JN, Rosenberg OS. PMID: 28252385; PMCID: PMC5364026.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 2017 01 10; 6.
Celona B, Dollen JV, Vatsavayai SC, Kashima R, Johnson JR, Tang AA, Hata A, Miller BL, Huang EJ, Krogan NJ, Seeley WW, Black BL. PMID: 28072389; PMCID: PMC5283830.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands. Mol Pharmacol. 2017 Feb; 91(2):145-156.
Tsvetanova NG, Trester-Zedlitz M, Newton BW, Riordan DP, Sundaram AB, Johnson JR, Krogan NJ, von Zastrow M. PMID: 27879340; PMCID: PMC5267521.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate. Neuron. 2016 Nov 23; 92(4):813-828.
Jayaraman D, Kodani A, Gonzalez DM, Mancias JD, Mochida GH, Vagnoni C, Johnson J, Krogan N, Harper JW, Reiter JF, Yu TW, Bae BI, Walsh CA. PMID: 27974163; PMCID: PMC5199216.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa. Mol Microbiol. 2016 08; 101(4):590-605.
Inclan YF, Persat A, Greninger A, Von Dollen J, Johnson J, Krogan N, Gitai Z, Engel JN. PMID: 27145134; PMCID: PMC4980298.
View in:
PubMed Mentions:
23 Fields:
Translation:
Cells
-
Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. Cell Host Microbe. 2015 Dec 09; 18(6):723-35.
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK. PMID: 26651948; PMCID: PMC4829074.
View in:
PubMed Mentions:
358 Translation:
HumansAnimalsCells
-
Discovery and functional characterization of a neomorphic PTEN mutation. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):13976-81.
Costa HA, Leitner MG, Sos ML, Mavrantoni A, Rychkova A, Johnson JR, Newton BW, Yee MC, De La Vega FM, Ford JM, Krogan NJ, Shokat KM, Oliver D, Halaszovich CR, Bustamante CD. PMID: 26504226; PMCID: PMC4653168.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015 Oct; 21(10):1154-62.
Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. PMID: 26390242; PMCID: PMC4598295.
View in:
PubMed Mentions:
161 Fields:
Translation:
HumansAnimalsCells
-
Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes. PLoS Comput Biol. 2015 Aug; 11(8):e1004362.
Johnson JR, Santos SD, Johnson T, Pieper U, Strumillo M, Wagih O, Sali A, Krogan NJ, Beltrao P. PMID: 26312481; PMCID: PMC4552029.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. Elife. 2015 Aug 22; 4.
Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF. PMID: 26297806; PMCID: PMC4574112.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
-
Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1. Biochemistry. 2015 Jul 28; 54(29):4423-6.
Mark KG, Meza-Gutierrez F, Johnson JR, Newton BW, Krogan NJ, Toczyski DP. PMID: 26161950; PMCID: PMC4816488.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. Cell Host Microbe. 2015 Jul 08; 18(1):109-21.
Mirrashidi KM, Elwell CA, Verschueren E, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, Jäger S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, Penn B, Shales M, Cox JS, Starnbach MN, Derre I, Valdivia R, Krogan NJ, Engel J. PMID: 26118995; PMCID: PMC4540348.
View in:
PubMed Mentions:
78 Translation:
HumansCells
-
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. 2015 May 26; 11(8):1236-50.
Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ. PMID: 25981045; PMCID: PMC4613747.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
-
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314.
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391; PMCID: PMC4426669.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansCells
-
NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer. Cell Rep. 2015 Apr 07; 11(1):98-110.
Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, Krogan NJ, Bivona TG. PMID: 25843712; PMCID: PMC4394036.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansCells
-
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. Mol Cell. 2015 Jan 22; 57(2):329-340.
Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M. PMID: 25616068; PMCID: PMC4305532.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
-
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Mol Cell. 2015 Jan 22; 57(2):349-60.
Davis ZH, Verschueren E, Jang GM, Kleffman K, Johnson JR, Park J, Von Dollen J, Maher MC, Johnson T, Newton W, Jäger S, Shales M, Horner J, Hernandez RD, Krogan NJ, Glaunsinger BA. PMID: 25544563; PMCID: PMC4305015.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
-
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Cancer Discov. 2015 02; 5(2):154-67.
Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. PMID: 25501949; PMCID: PMC4407699.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
-
Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes Dev. 2014 Nov 15; 28(22):2547-63.
Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT. PMID: 25403183; PMCID: PMC4233246.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Mol Cell Biol. 2015 Jan; 35(2):468-78.
Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM. PMID: 25384976; PMCID: PMC4272423.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1. Mol Cell Proteomics. 2015 Jan; 14(1):162-76.
Downey M, Johnson JR, Davey NE, Newton BW, Johnson TL, Galaang S, Seller CA, Krogan N, Toczyski DP. PMID: 25381059; PMCID: PMC4288252.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
-
Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. Nat Protoc. 2014 Nov; 9(11):2539-54.
Morris JH, Knudsen GM, Verschueren E, Johnson JR, Cimermancic P, Greninger AL, Pico AR. PMID: 25275790; PMCID: PMC4332878.
View in:
PubMed Mentions:
62 Fields:
-
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E15-24.
Lu H, Li Z, Xue Y, Schulze-Gahmen U, Johnson JR, Krogan NJ, Alber T, Zhou Q. PMID: 24367103; PMCID: PMC3890890.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014 Jan 24; 343(6169):428-32.
Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. PMID: 24356113; PMCID: PMC3976200.
View in:
PubMed Mentions:
216 Fields:
Translation:
HumansCells
-
Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation. Cell Rep. 2013 Jun 27; 3(6):2168-78.
Haber JE, Braberg H, Wu Q, Alexander R, Haase J, Ryan C, Lipkin-Moore Z, Franks-Skiba KE, Johnson T, Shales M, Lenstra TL, Holstege FC, Johnson JR, Bloom K, Krogan NJ. PMID: 23746449; PMCID: PMC3718395.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. J Mol Biol. 2013 Apr 12; 425(7):1172-82.
Albin JS, Anderson JS, Johnson JR, Harjes E, Matsuo H, Krogan NJ, Harris RS. PMID: 23318957; PMCID: PMC3602375.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. ACS Chem Biol. 2012 Mar 16; 7(3):506-17.
Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. PMID: 22181350; PMCID: PMC3306499.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
-
Global landscape of HIV-human protein complexes. Nature. 2011 Dec 21; 481(7381):365-70.
Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ. PMID: 22190034; PMCID: PMC3310911.
View in:
PubMed Mentions:
319 Fields:
Translation:
HumansCells
-
Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. Mol Cell Proteomics. 2012 Apr; 11(4):M111.015313.
Naji S, Ambrus G, Cimermancic P, Reyes JR, Johnson JR, Filbrandt R, Huber MD, Vesely P, Krogan NJ, Yates JR, Saphire AC, Gerace L. PMID: 22174317; PMCID: PMC3322577.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCells
-
The Anopheles gambiae adult midgut peritrophic matrix proteome. Insect Biochem Mol Biol. 2009 Feb; 39(2):125-34.
Dinglasan RR, Devenport M, Florens L, Johnson JR, McHugh CA, Donnelly-Doman M, Carucci DJ, Yates JR, Jacobs-Lorena M. PMID: 19038338; PMCID: PMC2684889.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
-
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum. BMC Genomics. 2008 Oct 30; 9:513.
Le Roch KG, Johnson JR, Ahiboh H, Chung DW, Prudhomme J, Plouffe D, Henson K, Zhou Y, Witola W, Yates JR, Mamoun CB, Winzeler EA, Vial H. PMID: 18973684; PMCID: PMC2596145.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
-
Proteomic analysis of zygote and ookinete stages of the avian malaria parasite Plasmodium gallinaceum delineates the homologous proteomes of the lethal human malaria parasite Plasmodium falciparum. Proteomics. 2008 Jun; 8(12):2492-9.
Patra KP, Johnson JR, Cantin GT, Yates JR, Vinetz JM. PMID: 18563747; PMCID: PMC2637033.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. Nat Chem Biol. 2008 Jun; 4(6):347-56.
Kato N, Sakata T, Breton G, Le Roch KG, Nagle A, Andersen C, Bursulaya B, Henson K, Johnson J, Kumar KA, Marr F, Mason D, McNamara C, Plouffe D, Ramachandran V, Spooner M, Tuntland T, Zhou Y, Peters EC, Chatterjee A, Schultz PG, Ward GE, Gray N, Harper J, Winzeler EA. PMID: 18454143.
View in:
PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
-
In silico discovery of transcription regulatory elements in Plasmodium falciparum. BMC Genomics. 2008 Feb 07; 9:70.
Young JA, Johnson JR, Benner C, Yan SF, Chen K, Le Roch KG, Zhou Y, Winzeler EA. PMID: 18257930; PMCID: PMC2268928.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
-
Quantitative mass spectrometry identifies insulin signaling targets in C. elegans. Science. 2007 Aug 03; 317(5838):660-3.
Dong MQ, Venable JD, Au N, Xu T, Park SK, Cociorva D, Johnson JR, Dillin A, Yates JR. PMID: 17673661.
View in:
PubMed Mentions:
135 Fields:
Translation:
AnimalsCells
-
Proteomic analysis of Schistosoma mansoni egg secretions. Mol Biochem Parasitol. 2007 Oct; 155(2):84-93.
Cass CL, Johnson JR, Califf LL, Xu T, Hernandez HJ, Stadecker MJ, Yates JR, Williams DL. PMID: 17644200; PMCID: PMC2077830.
View in:
PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
-
A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog. 2006 Jun; 2(6):e57.
Kidgell C, Volkman SK, Daily J, Borevitz JO, Plouffe D, Zhou Y, Johnson JR, Le Roch K, Sarr O, Ndir O, Mboup S, Batalov S, Wirth DF, Winzeler EA. PMID: 16789840; PMCID: PMC1480597.
View in:
PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
-
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog. 2006 Feb; 2(2):e13.
Hu K, Johnson J, Florens L, Fraunholz M, Suravajjala S, DiLullo C, Yates J, Roos DS, Murray JM. PMID: 16518471; PMCID: PMC1383488.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
-
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle. Genome Res. 2004 Nov; 14(11):2308-18.
Le Roch KG, Johnson JR, Florens L, Zhou Y, Santrosyan A, Grainger M, Yan SF, Williamson KC, Holder AA, Carucci DJ, Yates JR, Winzeler EA. PMID: 15520293; PMCID: PMC525690.
View in:
PubMed Mentions:
189 Fields:
Translation:
AnimalsCells
-
Functional characterization of an LCCL-lectin domain containing protein family in Plasmodium berghei. J Parasitol. 2004 Oct; 90(5):1062-71.
Trueman HE, Raine JD, Florens L, Dessens JT, Mendoza J, Johnson J, Waller CC, Delrieu I, Holders AA, Langhorne J, Carucci DJ, Yates JR, Sinden RE. PMID: 15562607.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling. Genome Res. 2004 Jun; 14(6):1052-9.
Sam-Yellowe TY, Florens L, Johnson JR, Wang T, Drazba JA, Le Roch KG, Zhou Y, Batalov S, Carucci DJ, Winzeler EA, Yates JR. PMID: 15140830; PMCID: PMC419783.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
-
The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion. Mol Microbiol. 2004 Apr; 52(1):107-18.
Ling IT, Florens L, Dluzewski AR, Kaneko O, Grainger M, Yim Lim BY, Tsuboi T, Hopkins JM, Johnson JR, Torii M, Bannister LH, Yates JR, Holder AA, Mattei D. PMID: 15049814.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Proteomics in malaria. J Proteome Res. 2004 Mar-Apr; 3(2):296-306.
Johnson JR, Florens L, Carucci DJ, Yates JR. PMID: 15113107.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications. Rapid Commun Mass Spectrom. 2004; 18(18):2162-8.
McDonald WH, Tabb DL, Sadygov RG, MacCoss MJ, Venable J, Graumann J, Johnson JR, Cociorva D, Yates JR. PMID: 15317041.
View in:
PubMed Mentions:
192 Fields:
-
Fourier-transform mass spectrometry for automated fragmentation and identification of 5-20 kDa proteins in mixtures. Electrophoresis. 2002 Sep; 23(18):3217-23.
Johnson JR, Meng F, Forbes AJ, Cargile BJ, Kelleher NL. PMID: 12298093.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
-
Processing complex mixtures of intact proteins for direct analysis by mass spectrometry. Anal Chem. 2002 Jul 01; 74(13):2923-9.
Meng F, Cargile BJ, Patrie SM, Johnson JR, McLoughlin SM, Kelleher NL. PMID: 12141648.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Informatics and multiplexing of intact protein identification in bacteria and the archaea. Nat Biotechnol. 2001 Oct; 19(10):952-7.
Meng F, Cargile BJ, Miller LM, Forbes AJ, Johnson JR, Kelleher NL. PMID: 11581661.
View in:
PubMed Mentions:
80 Fields:
Translation:
Cells