Loading...

Jeffrey Milush, PhD

TitleAssociate Professor
SchoolUCSF School of Medicine
DepartmentMedicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-206-3881
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of Texas Southwestern Medical Center, DallasMolecular Microbiology2005Microbiology
    University of Texas Southwestern Medical Center, DallasPostdoctoral StudiesInfectious Diseases
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Role of Monocyte Oxidative Stress and Mineralocorticoid Receptor Signaling on Cardiovascular Disease and Persistent Inflammation in Antiretroviral-Treated HIV+ Persons
    NIH/NHLBI R21HL128123Sep 1, 2015 - Jun 30, 2017
    Role: Principal Investigator
    Molecular effects of mind-body intervention on GC sensitivity and immune function
    NIH/NCCIH K01AT006153Apr 1, 2011 - Mar 31, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Gurfein BT, Hasdemir B, Milush J, Touma C, Palme R, Nixon DF, Darcel N, Hecht FM, Bhargava A. Enriched environment and stress exposure influence splenic B lymphocyte composition. PLoS One. 2017; 12(7):e0180771. PMID: 28704473.
      View in: PubMed
    2. Ribeiro SP, Milush J, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D. Correction: p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2017; 12(4):e0176509. PMID: 28426830.
      View in: PubMed
    3. Tomiyama AJ, Milush J, Lin J, Flynn JM, Kapahi P, Verdin E, Sinclair E, Melov S, Epel ES. Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. Nutr Healthy Aging. 2017 Mar 31; 4(2):147-156. PMID: 28447069.
      View in: PubMed
    4. Pereira Ribeiro S, M Milush J, Cunha-Neto E, G Kallas E, Kalil J, D Passero LF, W Hunt P, G Deeks S, F Nixon D, SenGupta D. p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2016; 11(11):e0166759. PMID: 27861555.
      View in: PubMed
    5. Aschbacher K, Milush J, Gilbert A, Almeida C, Sinclair E, Epling L, Grenon SM, Marco EJ, Puterman E, Epel E, et al. Chronic stress is associated with reduced circulating hematopoietic progenitor cell number: A maternal caregiving model. Brain Behav Immun. 2017 Jan; 59:245-252. PMID: 27622676.
      View in: PubMed
    6. Bersani FS, Wolkowitz OM, Milush J, Sinclair E, Eppling L, Aschbacher K, Lindqvist D, Yehuda R, Flory J, Bierer LM, Matokine I, Abu-Amara D, Reus VI, Coy M, Hough CM, Marmar CR, Mellon SH. A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity. Brain Behav Immun. 2016 Aug; 56:264-70. PMID: 27025668.
      View in: PubMed
    7. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush J, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Obesity (Silver Spring). 2016 Apr; 24(4):794-804. PMID: 26955895; PMCID: PMC4898945 [Available on 04/01/17].
    8. Kuebler PJ, Mehrotra ML, Shaw BI, Leadabrand KS, Milush J, York VA, Defechereux P, Grant RM, Kallás EG, Nixon DF. Persistent HIV Type 1 Seronegative Status Is Associated With Lower CD8+ T-Cell Activation. J Infect Dis. 2016 Feb 15; 213(4):569-73. PMID: 26310308; PMCID: PMC4721903 [Available on 02/15/17].
    9. Kuebler PJ, Mehrotra ML, McConnell JJ, Holditch SJ, Shaw BI, Tarosso LF, Leadabrand KS, Milush J, York VA, Raposo RA, Cheng RG, Eriksson EM, McMahan V, Glidden DV, Shiboski S, Grant RM, Nixon DF, Kallás EG. Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8379-84. PMID: 26100867; PMCID: PMC4500209.
    10. York VA, Milush J, et al. Ex vivo Human Natural Killer (NK) Cell Stimulation and Intracellular IFN? and CD107a Cytokine Staining. Bio Protoc. 2015 Jun 20; 5(12). PMID: 27453912.
      View in: PubMed
    11. Ribeiro SP, Milush J, Cunha-Neto E, Kallas EG, Kalil J, Somsouk M, Hunt PW, Deeks SG, Nixon DF, SenGupta D. The CD8? memory stem T cell (T(SCM)) subset is associated with improved prognosis in chronic HIV-1 infection. J Virol. 2014 Dec; 88(23):13836-44. PMID: 25253339; PMCID: PMC4248986.
    12. Gurfein BT, Davidenko O, Premenko-Lanier M, Milush J, Acree M, Dallman MF, Touma C, Palme R, York VA, Fromentin G, Darcel N, Nixon DF, Hecht FM. Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice. Mol Med. 2014 Apr 22; 20:179-90. PMID: 24687160; PMCID: PMC4002849.
    13. Milush J, López-Vergès S, York VA, Deeks SG, Martin JN, Hecht FM, Lanier LL, Nixon DF. CD56negCD16? NK cells are activated mature NK cells with impaired effector function during HIV-1 infection. Retrovirology. 2013 Dec 18; 10:158. PMID: 24351015; PMCID: PMC3892122.
    14. Milush J, Chen HL, Atteberry G, Sodora DL. Early detection of simian immunodeficiency virus in the central nervous system following oral administration to rhesus macaques. Front Immunol. 2013; 4:236. PMID: 23966995; PMCID: PMC3743037.
    15. Snyder-Cappione JE, Nixon DF, Chi JC, Nguyen ML, Kirby CK, Milush J, Koth LL. Invariant natural killer T (iNKT) cell exhaustion in sarcoidosis. Eur J Immunol. 2013 Aug; 43(8):2194-205. PMID: 23661497; PMCID: PMC3869389.
    16. Batista MD, Tincati C, Milush J, Ho EL, Ndhlovu LC, York VA, Kallas EG, Kalil J, Keating SM, Norris PJ, Chang D, Unemori P, Leslie KS, Maurer T, Liao W, Nixon DF. CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis. PLoS One. 2013; 8(2):e52144. PMID: 23468834; PMCID: PMC3585296.
    17. Perez CL, Milush J, Buggert M, Eriksson EM, Larsen MV, Liegler T, Hartogensis W, Bacchetti P, Lund O, Hecht FM, Nixon DF, Karlsson AC. Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion. AIDS Res Hum Retroviruses. 2013 Mar; 29(3):602-12. PMID: 23140171; PMCID: PMC3581067.
    18. Batista MD, Ho EL, Kuebler PJ, Milush J, Lanier LL, Kallas EG, York VA, Chang D, Liao W, Unemori P, Leslie KS, Maurer T, Nixon DF. Skewed distribution of natural killer cells in psoriasis skin lesions. Exp Dermatol. 2013 Jan; 22(1):64-6. PMID: 23278897; PMCID: PMC3777400.
    19. Gurfein BT, Stamm AW, Bacchetti P, Dallman MF, Nadkarni NA, Milush J, Touma C, Palme R, Di Borgo CP, Fromentin G, Lown-Hecht R, Konsman JP, Acree M, Premenko-Lanier M, Darcel N, Hecht FM, Nixon DF. The calm mouse: an animal model of stress reduction. Mol Med. 2012 May 09; 18:606-17. PMID: 22398685; PMCID: PMC3388136.
    20. de Vos G, Milush J, Aaron J, Pichardo Y, York VA, Nazari R, Rosenstreich D, Nixon DF, Wiznia A. Peripheral CD8+ T-cell levels are decreased in atopic wheezing children aged less than 4 years. J Investig Allergol Clin Immunol. 2012; 22(6):442-4. PMID: 23101192.
      View in: PubMed
    21. Eriksson EM, Milush J, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF. Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Blood. 2012 Jan 19; 119(3):745-55. PMID: 22134167; PMCID: PMC3265199.
    22. Lopez-Vergès S, Milush J, Schwartz BS, Pando MJ, Jarjoura J, York VA, Houchins JP, Miller S, Kang SM, Norris PJ, Nixon DF, Lanier LL. Expansion of a unique CD57?NKG2Chi natural killer cell subset during acute human cytomegalovirus infection. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14725-32. PMID: 21825173; PMCID: PMC3169160.
    23. Durudas A, Chen HL, Gasper MA, Sundaravaradan V, Milush J, Silvestri G, Johnson W, Giavedoni LD, Sodora DL. Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques. Curr HIV Res. 2011 Jul; 9(5):276-88. PMID: 21861823; PMCID: PMC3337698.
    24. Milush J, Mir KD, Sundaravaradan V, Gordon SN, Engram J, Cano CA, Reeves JD, Anton E, O'Neill E, Butler E, Hancock K, Cole KS, Brenchley JM, Else JG, Silvestri G, Sodora DL. Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells. J Clin Invest. 2011 Mar; 121(3):1102-10. PMID: 21317533; PMCID: PMC3049370.
    25. Lopez-Vergès S, Milush J, Pandey S, York VA, Arakawa-Hoyt J, Pircher H, Norris PJ, Nixon DF, Lanier LL. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood. 2010 Nov 11; 116(19):3865-74. PMID: 20733159; PMCID: PMC2981540.
    26. Milush J, Long BR, Snyder-Cappione JE, Cappione AJ, York VA, Ndhlovu LC, Lanier LL, Michaëlsson J, Nixon DF. Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4. Blood. 2009 Nov 26; 114(23):4823-31. PMID: 19805616; PMCID: PMC2786291.
    27. Durudas A, Milush J, Chen HL, Engram JC, Silvestri G, Sodora DL. Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys. J Virol. 2009 Dec; 83(23):12229-40. PMID: 19759147; PMCID: PMC2786739.
    28. Kosub DA, Durudas A, Lehrman G, Milush J, Cano CA, Jain MK, Sodora DL. Gamma/Delta T cell mRNA levels decrease at mucosal sites and increase at lymphoid sites following an oral SIV infection of macaques. Curr HIV Res. 2008 Nov; 6(6):520-30. PMID: 18991617; PMCID: PMC2777980.
    29. Kosub DA, Lehrman G, Milush J, Zhou D, Chacko E, Leone A, Gordon S, Silvestri G, Else JG, Keiser P, Jain MK, Sodora DL. Gamma/Delta T-cell functional responses differ after pathogenic human immunodeficiency virus and nonpathogenic simian immunodeficiency virus infections. J Virol. 2008 Feb; 82(3):1155-65. PMID: 18045946; PMCID: PMC2224435.
    30. Milush J, Reeves JD, Gordon SN, Zhou D, Muthukumar A, Kosub DA, Chacko E, Giavedoni LD, Ibegbu CC, Cole KS, Miamidian JL, Paiardini M, Barry AP, Staprans SI, Silvestri G, Sodora DL. Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host. J Immunol. 2007 Sep 01; 179(5):3047-56. PMID: 17709519.
      View in: PubMed
    31. Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush J, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G. Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys. J Immunol. 2007 Sep 01; 179(5):3026-34. PMID: 17709517; PMCID: PMC2365740.
    32. Apetrei C, Gautam R, Sumpter B, Carter AC, Gaufin T, Staprans SI, Else J, Barnes M, Cao R, Garg S, Milush J, Sodora DL, Pandrea I, Silvestri G. Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys. J Virol. 2007 Aug; 81(15):7913-23. PMID: 17507488; PMCID: PMC1951324.
    33. Milush J, Stefano-Cole K, Schmidt K, Durudas A, Pandrea I, Sodora DL. Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques. J Virol. 2007 Jun; 81(12):6175-86. PMID: 17428863; PMCID: PMC1900075.
    34. Sumpter B, Dunham R, Gordon S, Engram J, Hennessy M, Kinter A, Paiardini M, Cervasi B, Klatt N, McClure H, Milush J, Staprans S, Sodora DL, Silvestri G. Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis. J Immunol. 2007 Feb 01; 178(3):1680-91. PMID: 17237418.
      View in: PubMed
    35. Estes JD, Wietgrefe S, Schacker T, Southern P, Beilman G, Reilly C, Milush J, Lifson JD, Sodora DL, Carlis JV, Haase AT. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J Infect Dis. 2007 Feb 15; 195(4):551-61. PMID: 17230415.
      View in: PubMed
    36. Milush J, Kosub D, Marthas M, Schmidt K, Scott F, Wozniakowski A, Brown C, Westmoreland S, Sodora DL. Rapid dissemination of SIV following oral inoculation. AIDS. 2004 Dec 03; 18(18):2371-80. PMID: 15622313.
      View in: PubMed
    37. Sodora DL, Milush J, Ware F, Wozniakowski A, Montgomery L, McClure HM, Lackner AA, Marthas M, Hirsch V, Johnson RP, Douek DC, Koup RA. Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus. J Virol. 2002 Oct; 76(19):9981-90. PMID: 12208974; PMCID: PMC136511.
    Jeffrey's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP